Clinical trials: Paroxysmal Arrhythmia
Atrial Fibrillation (AF)
Assessment of Catheter Tissue Contact in PFA
Pulmonary vein isolation remains the cornerstone of invasive treatment for atrial fibrlllation. Despite recent technological advances in the field of pulsed field ablation (PFA) pulmonary vein isolation durability and arrhythmia…
- Trial name
- ASSESS PFA (NCT07721948)
- Testing
- Electrode tissue contact assessment during pulsed field ablation
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Persistent Atrial Fibrillation, Long-standing Persistent Atrial Fibrillation
Pulmonary Vein Antrum Isolation (PVAI) Plus Scar Homogenization and Non-PV Triggers Ensure Long-term Recurrence-free Survival in Non-paroxysmal Atrial Fibrillation
This study aims to examine the long-term success rate of catheter ablation in non-paroxysmal atrial fibrillation patients using different ablation strategies such as : (i) pulmonary vein antrum isolation (PVAI) + isolation of…
- Trial name
- TANTRA (NCT01672138)
- Testing
- Pulmonary Vein Antrum Isolation, scar homogenization, Non-PV triggers ablation
- Where
- 2 sites in United States
- Volunteers
- 186 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Atrial Fibrillation
Evaluation of Proper Radiofrequency Catheter Ablation Strategy for the Patients Who Were Changed to Paroxysmal Atrial Fibrillation From Persistent Atrial Fibrillation
1. Purpose of the study 1) To compare clinical outcome, procedure time, complication rate of patients who were changed to paroxysmal atrial fibrillation from persistent atrial fibrillation between ablation with conventional…
- Trial name
- NCT02176616
- Testing
- linear ablation, pulmonary vein isolation
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Yonsei University
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias
The primary purpose of this Registry is to assess procedural safety and long-term effectiveness of catheter ablations in the treatment of subjects with PAF, PsAF, and VA.
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Ventricular Arrhythmia
- Trial name
- REAL Registry (NCT04088071)
- Testing
- Catheter ablation
- Where
- 75 sites in United States, Canada
- Volunteers
- 20,000 people
- Sponsor
- Heart Rhythm Clinical and Research Solutions, LLC
Atrial Fibrillation
To Evaluate the Impact of Oral Flecainide on Quality of Life in Patients With Paroxysmal Atrial Fibrillation
The purpose of this study is to evaluate the management of paroxysmal atrial fibrillation with controlled release flecainide on patient's quality of life.
- Trial name
- NCT00189319
- Testing
- Flecainide controlled release
- Where
- France
- Volunteers
- 200 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Paroxysmal Atrial Fibrillation
Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation as First-line Therapy
Cryoballoon ablation of paroxysmal atrial fibrillation can be used as first-line therapy compared to second choice after failed medical therapy
- Trial name
- C-frost (NCT01920295)
- Testing
- Cryoballoon ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuksek Ihtisas Hospital
Paroxysmal Atrial Fibrillation, Indications for CABG
Botulinum Toxin Injection in Epicardial Fat Pads To Treat Atrial Fibrillation After Cardiac Surgery
The aim of this prospective randomized double-blind study was to compare the efficacy and safety of Botulinum toxin injection in epicardial fat pads for preventing recurrences (in early postoperative period) of atrial…
- Trial name
- NCT01842529
- Testing
- botulinum toxin injection, 0.9% normal saline injection, Implantable loop recorder
- Where
- 3 sites in United States, Russia
- Volunteers
- 60 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Essential Hypertension, Atrial Fibrillation
Efficacy of Perindopril to Prevent Recurrence of Atrial Fibrillation in Patients With Essential Hypertension
The purpose of this 7- to 13-month study is to determine the efficacy of 8 mg/day oral perindopril to prevent the recurrence of atrial fibrillation (AF) in patients with essential hypertension.
- Trial name
- CTAF-2 (NCT00461903)
- Testing
- Perindopril
- Where
- Canada
- Volunteers
- 316 people
- Sponsor
- Montreal Heart Institute
Paroxysmal Atrial Fibrillation
TactiFlex Paroxysmal Atrial Fibrillation IDE Trial
Prospective non-randomized parallel-assignment multi-center clinical investigation. The study design includes two subject cohorts: 1) Paroxysmal Atrial Fibrillation Main Study, and 2) Paroxysmal Atrial Fibrillation High Standard…
- Trial name
- NCT04356040
- Testing
- TactiFlex SE, TactiFlex SE - High Standard Power
- Where
- 45 sites in United States, Australia and 8 more
- Volunteers
- 355 people
- Sponsor
- Abbott Medical Devices
Paroxysmal Atrial Fibrillation
Clinical Investigation of the VytronUS Ablation System for Treatment of Paroxysmal Atrial Fibrillation
The study is a single center, open-label, single arm, prospective pre-market study designed to assess the safety and efficacy of the VytronUS Ablation System (VAS) for the treatment of atrial fibrillation in patients with drug…
- Trial name
- VALUE (NCT03639597)
- Testing
- VytronUS Ablation System
- Where
- Czechia
- Volunteers
- 53 people
- Sponsor
- VytronUS, Inc.