Clinical trials: Paroxysmal Atrial Fibrillation (PAF)
Atrial Fibrillation
Efficacy and Safety Study of an Antiarrhythmic Drug to Treat Atrial Fibrillation in Patients With Pacemakers
The purpose of this study is to determine the safety and efficacy of an investigational antiarrhythmic drug (ATI-2042) in the treatment of atrial fibrillation in patients with a dual chamber pacemaker.
- Trial name
- NCT00389792
- Testing
- ATI-2042, ATI-2042 200 mg
- Where
- 40 sites in United States, Canada
- Volunteers
- 72 people
- Sponsor
- ARYx Therapeutics
CBT
Effects of Cognitive Behavior Therapy on Quality of Life in Paroxysmal Atrial Fibrillation Patients
Health-Related Quality of Life (HRQoL) was commonly impaired in atrial fibrillation patients. Depression, anxiety, and illness perception are psychological correlates of HRQoL.
- Trial name
- NCT05893615
- Testing
- Cognitive Behaviour Therapy
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Peking University People's Hospital
Non-paroxysmal Atrial Fibrillation
LAA Clipping Versus NOACs to Prevent Stroke in Non-paroxysmal Atrial Fibrillation.
This trial is designed to examine the hypothesis that thoracoscopic LAA clipping is superior to NOACs for stroke, systemic embolism, all-cause mortality, major bleeding events and clinically relevant nonmajor bleeding events in…
- Trial name
- NCT06021808
- Testing
- Thoracoscopic LAA clipping, Novel oral anticoagulant
- Where
- China
- Volunteers
- 290 people
- Sponsor
- China National Center for Cardiovascular Diseases
Paroxysmal Atrial Fibrillation (PAF)
Sphere-9 PAF China Study
The goal of this clinical trial is to find out if the Sphere-9 Catheter and Affera Integrated Mapping and Ablation System is safe and works to treat recurrent symptomatic paroxysmal atrial fibrillation (PAF) in adults who have…
- Trial name
- NCT07789925
- Testing
- Catheter ablation using Sphere-9™ Catheter and Affera™ Integrated Mapping and Ablation System
- Where
- 10 sites in China
- Volunteers
- 180 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Paroxysmal Atrial Fibrillation
Atrial Fibrillation Force Contact Ablation Study
This study will be divided into two phases. The purpose of the Phase I registry is to assess the current force being used for ablation of symptomatic paroxysmal AF in a wide range of operators in different Canadian centres with…
- Trial name
- CAFCAS (NCT01693107)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Atrial Fibrillation Paroxysmal
Posterior Wall Substrate Modification Using Irreversible Electroporation for Paroxysmal Atrial Fibrillation
The purpose of this study is to compare the efficacy and safety between pulmonary vein isolation (PVI) alone versus PVI with left atrial (LA) posterior wall isolation (PWI) using pulsed-field ablation (PFA) in the treatment of…
- Trial name
- (SMILE-AF) (NCT06364215)
- Testing
- Farapulse PFA, Pulmonary Vein Isolation alone, Farapulse PFA, Pulmonary Vein Isolation and Left atrial Posterior Wall Isolation
- Where
- 18 sites in United States
- Volunteers
- 198 people
- Sponsor
- Jorge Romero
Paroxysmal Atrial Fibrillation (PAF)
Grid eXplore Mapping Study
The purpose of the trial is to find out if the Grid X Mapping Catheter and EnSite X EP System with EnSite X Software v3.1.1, the devices that are being studied, are safe and effective in treating Chinese patients who have atrial…
- Trial name
- NCT07421076
- Testing
- Grid X and EnSite X v3.1.1 Software
- Where
- 5 sites in China
- Volunteers
- 200 people
- Sponsor
- Abbott Medical Devices
Paroxysmal Atrial Fibrillation
A RWS of the FARAPULSE in A Chinese Population With PAF
The real world study is a retrospective and/or prospective, single-center, single-arm observational study to observe the safety and effectiveness of the FARAPULSE Pulsed Field Ablation System for treatment of recurrent…
- Trial name
- NCT05493852
- Testing
- FARAPULSE Pulsed Field Ablation System
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Boston Scientific Corporation
Paroxysmal Atrial Fibrillation
Electrical Coupling Information From The Rhythmia HDx System And DirectSense Technology In Subjects With Paroxysmal Atrial Fibrillation
The objective of the study is to collect data on the use of the Rhythmia HDx mapping system running commercially available Software Version 2.0 or any future commercially available Software Version with DirectSense technology and…
- Trial name
- LOCALIZE (NCT03232645)
- Testing
- Ablation procedure
- Where
- 6 sites in France, Germany and 2 more
- Volunteers
- 62 people
- Sponsor
- Boston Scientific Corporation
Paroxysmal Atrial Fibrillation, Cryptogenic Stroke
Smartwatch and External Holter Monitoring to Detect Atrial Fibrillation in Patients With Cryptogenic Stroke
Stroke recurrence largely depends on the detection of the cause and the control of vascular risk factors, with occult atrial fibrillation (AF) being one of the most important.
- Trial name
- SMARTTHUNDER (NCT05565781)
- Testing
- ECG smartwatch, Insertable Cardiac Monitor (ICM), External ECG Monitoring
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Atrial Fibrillation
CLOSE to CURE Study
Title: CLOSE-guided pulmonary vein isolation (PVI) as Cure for Paroxysmal Atrial Fibrillation ('CLOSE to CURE' study) Design: This is a prospective, observational, single-center, unblinded, clinical 3-year study.
- Trial name
- NCT02925624
- Testing
- Pulmonary vein isolation
- Where
- Belgium
- Volunteers
- 105 people
- Sponsor
- AZ Sint-Jan AV
Atrial Fibrillation, Paroxysmal Atrial Fibrillation
A Study of the Acceptability and Performance of Wearables for Atrial Fibrillation Screening in Older Adults
--- Background and study aim Atrial fibrillation (AF) is an irregular heart rhythm which causes a five-fold increase in the risk of stroke. Approximately one in ten people aged over 70 have AF.
- Trial name
- NCT04715555
- Testing
- Electrocardiogram monitoring, Electrocardiogram recording, Photoplethysmogram monitoring
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- University of Cambridge
Atrial Fibrillation
Comparison of Different Ablation Surgeries on Left Atrial Reverse Remodeling in Patients With Atrial Fibrillation
The goal of this Ambispective cohort Study is to compare in patients with paroxysmal atrial fibrillation undergo pulse field ablation and radiofrequency ablation, respectively.
- Trial name
- NCT06307860
- Testing
- pulsed field ablation, radiofrequency ablation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yun Wan
Atrial Fibrillation and Flutter, Atrial Fibrillation
HIgh Power Short Duration Radiofrequency Ablation or Cryoballoon Ablation for Paroxysmal Atrial Fibrillation
Pulmonary vein isolation (PVI) using the cryoballoon has been proven equal to RF-PVI and is widely used. High Power Short Duration Ablation in RF-PVI has been successfully tested in several trials.
- Conditions
- Atrial Fibrillation and Flutter, Atrial Fibrillation, Paroxysmal Atrial Fibrillation
- Trial name
- HIPAF (NCT04855890)
- Testing
- Ablation
- Where
- Germany
- Volunteers
- 170 people
- Sponsor
- Universitätsklinikum Köln
Paroxysmal Atrial Fibrillation
Guided Radiofrequency Ablation Using the CARTO® 3 and NavX™ Systems for the Treatment of Paroxysmal Atrial Fibrillation
The purpose of this study is to determine the change in median radiation exposure time and median procedure time following guided radiofrequency (RF) ablation among subjects undergoing treatment for paroxysmal atrial fibrillation…
- Trial name
- CO1 (NCT01036724)
- Testing
- Cardiac Mapping
- Where
- 6 sites in Canada
- Volunteers
- 107 people
- Sponsor
- Biosense Webster, Inc.
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Real-world Experience of Catheter Ablation Using Novel Ablation Technologies for the Treatment of Atrial Fibrillation
The primary purpose of this registry is to obtain real-world clinical experience for the latest and future ablation technologies when used in conjunction with the Carto system in the treatment of patients with atrial fibrillation…
- Trial name
- NOVEL AF (NCT05006456)
- Testing
- Catheter ablation
- Volunteers
- 4,000 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation
Singapore Atrial Fibrillation Study
Atrial fibrillation is a common disease in the aging population that has severe implication if left untreated as it leads to embolic stroke and other embolic phenomenon.
- Trial name
- SAFS (NCT02791022)
- Testing
- SPYDER ECG sensor
- Where
- Singapore
- Volunteers
- 2,500 people
- Sponsor
- National Heart Centre Singapore
Paroxysmal Atrial Fibrillation (PAF), Atrial Flutter
Home Monitor for AA Burden Detection IIT in TWN
Primary Endpoint: Early detection rate in Atrial Arrhythmia (AA) burden Data transmission success rate for overall number of atrial burden collection during the monitoring period Secondary Endpoints: Atrial burden occurrence at…
- Trial name
- FF108 (NCT07572279)
- Where
- 4 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation
Effect of Structural Remodeling on Scar Formation as Assessed by DE-MRI of the Left Atrium
The purpose of this study is to evaluate the impact of pre-ablation fibrosis on scar formation in the left atrium of the heart. This will be assessed by delayed enhancement magnetic resonance imaging and will be looked at in…
- Trial name
- RADAR (NCT01187914)
- Volunteers
- 40 people
- Sponsor
- University of Utah