Clinical trials: Partial
INCOMPLETE SPINAL CORD INJURY (ASIA D)
Effects of 6 Weeks High-intensity Interval Training Among Spinal Cord Injury
The training consists of 6 weeks of functional electrical stimulation leg cycling exercise (FES-LCE) program. The training program comprises of 2 visits per week. Each visit consists of FES-LCE for 45 minutes.
- Trial name
- NCT03837834
- Testing
- Functional Electrical Stimulation Leg Cycling Exercise
- Where
- Malaysia
- Volunteers
- 8 people
- Sponsor
- Universiti Teknologi Mara
Acromegaly
Phase II Study With ITF2984 in Acromegalic Patients
The purpose of this study is to investigate in acromegalic patients the effect of different doses of ITF2984 on GH and IGF-1 concentrations and to investigate safety and tolerability of three different doses of ITF2984.
- Trial name
- POC (NCT02111044)
- Testing
- Octreotide, ITF2984 500 mcg, ITF2984 1000 mcg
- Where
- 26 sites in Czechia, France and 7 more
- Volunteers
- 48 people
- Sponsor
- Italfarmaco
Depressive Disorder, Major
A Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive Disorder
The primary purpose is to study the efficacy, safety, and tolerability of LY2216684 as an adjunctive treatment for participants with major depressive disorder (MDD), who were identified as partial responders to an adequate course…
- Trial name
- NCT00840034
- Testing
- LY2216684
- Where
- 24 sites in United States
- Volunteers
- 227 people
- Sponsor
- Eli Lilly and Company
Tooth Loss, Partial Edentulism in the Maxilla or in the Mandible
Evaluation of Autogenous Bone Graft on Immediate Dental Implant Osseointegration Using Piezosurgery
This clinical study aims to evaluate the clinical and radiographic outcomes of immediate dental implant placement in mandibular premolar sites.
- Trial name
- ABG-IDIP (NCT07705399)
- Testing
- Immediate implant with autogenous bone graft, Immediate implant without bone graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Burn
Feasibility Study: Enzymatic Debridement in Patients With Partial Thickness Burns
Burns represent one of the most severe and dreaded traumas. Burned and traumatized tissue is known as eschar. The dead eschar, if not removed, often becomes heavily contaminated and is the source of local and/or systemic…
- Trial name
- NCT00898521
- Testing
- DGD
- Where
- 2 sites in India, Israel
- Volunteers
- 36 people
- Sponsor
- MediWound Ltd
Dysfunctional Voiding, Urinary Dysfunction
At-Home Diaphragmatic Interventions for Voiding Abnormalities (DIVA)
The goal of the DIVA trial is to test the effectiveness of at-home diaphragmatic breathing exercises with bladder hygiene education in female patients with symptoms of difficulty urinating (dysfunctional voiding).
- Trial name
- DIVA (NCT06165731)
- Testing
- Diaphragmatic Breathing Exercises, Bladder Hygiene Education
- Where
- 2 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Duke University
Sprain
Efficacy Study of a Sensory Feedback Knee Orthosis in Patients Suffering From Unoperated Severe Knee Sprain
Ortheses are commonly used for the repair of damage to the musculoskeletal system. However, immobility, by itself, causes serious side effects that require long and costly rehabilitation.
- Trial name
- ORTHOSENS (NCT01508728)
- Testing
- ORTHOSENS orthosis
- Where
- 3 sites in France
- Volunteers
- 104 people
- Sponsor
- Thuasne
Dental Caries
Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites
The purpose of this study is to determine the difference in success when placing implants immediately into an extraction site compared to delaying the implant placement until the extraction site has healed.
- Trial name
- NCT00067392
- Testing
- Dental Implant
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Depression
Repeated Partial Sleep Deprivation to Augment SSRI Response in Depression
The purpose of the study is to determine whether changing sleep patterns improves response to an antidepressant medication.
- Trial name
- NCT01545843
- Testing
- Sleep scheduling, Fluoxetine
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Michigan
Depressive Disorder
The Effect of Minocycline on Relapse After Successful Intravenous Ketamine/Minocycline-induced Symptoms Response in Subjects With Depression
The purpose of this study is to assess whether the antidepressant effect from intravenous (IV) ketamine treatment can be maintained by minocycline compared to placebo after IV ketamine treatment is stopped.
- Trial name
- NCT01809340
- Testing
- Minocycline, Ketamine
- Where
- 12 sites in Belgium, France and 2 more
- Volunteers
- 29 people
- Sponsor
- Janssen Research & Development, LLC
Subacromial Impingement Syndrome, Partial Thickness Rotator Cuff Tear
Treatment of the Rotator Cuff Disease With Platelet Rich Plasma Injection
The purpose of this investigator initiated study is to clinically evaluate the efficacy of a new treatment for subacromial impingement syndrome and partial thickness rotator cuff tears.
- Trial name
- NCT01123889
- Testing
- platelet rich plasma injection, corticosteroid injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Loma Linda University
Breast Cancer, Radiation Toxicity
Accelerated Partial Breast Irradiation With 3D-CRT and IMRT
The purpose of this study is to determine in a phase II clinical trial whether accelerated partial breast irradiation after breast conserving surgery using 3 dimensional external beam radiotherapy (3D-CRT) and intensity modulated…
- Conditions
- Breast Cancer, Radiation Toxicity, Side Effects
- Trial name
- APERT (NCT02003560)
- Testing
- accelerated partial breast irradiation
- Where
- Hungary
- Volunteers
- 90 people
- Sponsor
- National Institute of Oncology, Hungary
Meniscus Tear
Motor and Sensory Deficits Following Partial Meniscectomy
To determine changes in thigh muscle function and knee pain after a partial meniscectomy surgery and to also determine the effects of applying electrical stimulation to the knee to determine if this improves thigh muscle function…
- Trial name
- NCT02100059
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Creighton University
PaO2/FiO2 Ratio
The Effect of FiO2 on PaO2/FiO2 Ratio
The PaO2/FiO2 ratio is frequently used to determine the severity of lung injury in mechanically ventilated patients. However, several mathematical models have shown that PaO2/FiO2 ratio depends on FiO2.
- Trial name
- NCT03156218
- Testing
- Modulation of FiO2
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Amsterdam UMC, location VUmc
Pediatric Burns
Silver in Partial Thickness Pediatric Burns
Most burns in children are due to scalds and with proper dressings will heal on their own without the need for surgery such as skin grafting.
- Trial name
- NCT06971562
- Testing
- Aquacel AG, Aquacel
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Rectocele; Female, Rectocele and Incomplete Uterine Prolapse
3D vs 2D-laparoscopy for Rectocele and Rectal Prolapse Correction: a Prospective, Randomized, Single Center Study
The aim is to compare proximate and remote results of 3D and conventional 2D laparoscopic interventions in terms of efficacy and safety in treatment of symptomatic rectocele and rectal prolapse.
- Conditions
- Rectocele; Female, Rectocele and Incomplete Uterine Prolapse, Rectocele and Complete Uterovaginal Prolapse, Rectal Prolapse
- Trial name
- LARC (NCT04817150)
- Testing
- Laparoscopic ventral mesh rectopexy
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexander Khitaryan
Drug Resistant Epilepsy, Temporal Lobe Epilepsy
The GABAergic Inhibitory System in Drug Resistant Epilepsy
This study aims to investigate the effect of lovastatin on neurotransmission and neuroinflammation in patients with temporal lobe onset drug resistant epilepsy.
- Trial name
- NCT06789497
- Testing
- Lovastatin 60 MG
- Where
- Portugal
- Volunteers
- 5 people
- Sponsor
- University of Coimbra
Healthy
T/QT Study to Investigate the Effect of Relacorilant on Cardiac Repolarization in Healthy Volunteers
This dedicated T/QT study will investigate the effect of relacorilant on cardiac repolarization in healthy participants.
- Trial name
- NCT04795479
- Testing
- Relacorilant, Moxifloxacin
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Corcept Therapeutics
Breast Cancer
Hypofractionated PBI After BCS for Low-risk Breast Cancer Patients
The study was designed to evaluate the feasibility and safety of hypofractionated partial breast irradiation after breast-conserving surgery for low-risk breast cancer patients.
- Trial name
- NCT03411174
- Testing
- hypofractionated partial breast irradiation
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Fudan University
Dental Implant, Soft Tissue
Effect of Bone-related and Soft-tissue-related Variables on the Marginal Bone Loss of Platform-matched and Platform Switched Dental Implants
In this clinical trial the effect of the implant-abutment morphology (platform-switched vs platform matched) will be assessed in both soft tissue (soft tissue thickness) and hard tissue (marginal bone loss) outcomes.
- Conditions
- Dental Implant, Soft Tissue, Partial-edentulism, Bone Loss
- Trial name
- NCT05670340
- Testing
- Switched Prosthetic Profile, Matched Prosthetic Profile
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Salamanca