Clinical trials: Partial Nephrectomy
Urologic Cancer
Preoperative Guided Imagery in Patients Undergoing Urologic Surgery
This is a prospective randomized controlled trial of patients undergoing major urologic-oncologic surgery at the University of California, San Francisco (UCSF) Medical Center and the Helen Diller Family Comprehensive Cancer…
- Trial name
- NCT05072639
- Testing
- Guided Meditation
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- University of California, San Francisco
Renal Cell Carcinoma
Oncological and Perioperative Outcomes of Laparoscopic Versus Robotic Partial Nephrectomy for Treatment of Renal Tumors.
partial nephrectomy offers lower renal function impairment and equivalent oncological survival outcomes compared with radical nephrectomy in those with T1 tumors.
- Trial name
- NCT06424080
- Testing
- laparoscopic partial nephrectomy, robotic partial nephrectomy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Menoufia University
Kidney Neoplasm
A Pilot Study of Renal Hypothermia During Partial Nephrectomy
Renal hypothermia may preserve renal function in patients who require partial nephrectomy. In preparation for a definitive randomized controlled trial this pilot study will assess feasibility and variance data to be used for…
- Trial name
- NCT00888641
- Testing
- Hypothermia
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Acute Kidney Injury
Circulatory Management and Acute Kidney Injury in Patients Undergoing Partial Nephrectomy
The purpose of this study is to investigate whether circulatory management based on LiDCOrapid hemodynamic monitoring can reduce the incidence of acute kidney injury in patients undergoing partial nephrectomy when compared with…
- Trial name
- NCT02803372
- Testing
- Goal-directed circulatory management, Routine circulatory management
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University First Hospital
Robotic-Assisted Laparoscopic Partial Nephrectomy, Hemostatic Agents
Evaluation of Hemostatic Agents in Robotic-assisted Laparoscopic Partial Nephrectomy
The aim of this study is to evaluate whether Hemostatic Agents (HA) make a significant clinical difference in patient outcomes when used for Robotic-Assisted Laparoscopic Partial Nephrectomy (RALPN).
- Conditions
- Robotic-Assisted Laparoscopic Partial Nephrectomy, Hemostatic Agents, Renal Malignant Tumor
- Trial name
- NCT03528057
- Testing
- Hemostat
- Where
- United States
- Sponsor
- Northwestern University
Partial Nephrectomy, Kidney Cancer
Use of Human Dehydrated Amnion/Chorion (DHACM) Allograft in Partial Nephrectomy
After partial nephrectomy, kidney function decreases by about 10% overall and by about 20% in the operated kidney. This is primarily due to the loss of healthy parenchymal volume during resection of the tumor.
- Conditions
- Partial Nephrectomy, Kidney Cancer, Renal Function Aggravated
- Trial name
- NCT03323021
- Testing
- Dehydrated human amnion/chorion membrane, Standard of Care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- MiMedx Group, Inc.
Kidney Cancer
Effect of Papaverine on Renal Artery Blood Flow Volume
The purpose of this study is to evaluate the effect of papaverine on renal artery blood flow after declamping of renal artery.
- Trial name
- NCT04162834
- Testing
- Papaverine, Normal saline
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Asan Medical Center
Kidney Cancer
International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors
Partial nephrectomy (PN) is the standard treatment for localized renal masses and should be preferred in clinical T1 (<7 cm tumor diameter) renal tumors over radical nephrectomy (RN) whenever technically feasible.
- Trial name
- i-RECORd (NCT05363657)
- Testing
- Partial Nephrectomy (PN), Radical Nephrectomy (RN), Ablation therapy (AT)
- Where
- 37 sites in United States, Austria and 11 more
- Volunteers
- 10,000 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Renal Cell Carcinoma (RCC)
ClAmpless, Sutureless PartIAl Nephrectomy for Renal Masses
During partial nephrectomy surgery, efforts at minimizing ischemia while maximizing renal parenchymal volume are desirable to preserve renal function1,2.
- Trial name
- CASPIAN (NCT06722807)
- Testing
- sutureless, clampless partial nephrectomy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Florida
Kidney Tumor
Mixed Reality Technology in Laparoscopic Partial Nephrectomy
The aim of our study was: a) to evaluate the usefulness of the MR model for renal pedicle exposure and identification of the tumor's exact location during LPN, and b) to evaluate the subjective utility of the MR model as an…
- Trial name
- NCT05015179
- Testing
- mixed reality technology in laparoscopic partial nephrectomy
- Where
- Russia
- Volunteers
- 47 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Neoadjuvant Therapy of Non-metastatic Locally Advanced Renal Cell Carcinoma
Toripalimab Combined With Axitinib as Neoadjuvant Therapy in Patients With Non-metastatic Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinoma
This study is design to prospectively investigate the safety and efficacy of Toripalimab combined with Axitinib in downsizing tumors in patients with nonmetastatic biopsy-proven clear cell renal cell carcinoma.
- Trial name
- NCT04118855
- Testing
- Toripalimab, Axitinib
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Renal Cell Carcinoma (RCC), Renal Function Abnormal
Ischemic Preconditioning Reduces the Severity of Acute Kidney Injury After Partial Nephrectomy
It is demonstrated that remote ischemic preconditioning can alleviate the degree of acute renal injury on the operated side in patients undergoing partial nephrectomy.
- Trial name
- NCT07497958
- Testing
- Ischemic preconditioning, NO ischemic preconditioning
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Sun Yat-sen University
Reperfusion Injury
Remote Ischaemic PreConditioning (RIPC) in Partial Nephrectomy for the Prevention of Ischemia/Reperfusion Injury
"Remote Ischaemic PreConditioning" (RIPC) is performed prior to partial nephrectomy. Postoperative calprotectin dynamics and Blood Oxygen-Level-Dependent (BOLD) MRI are used to to demonstrate the potential renoprotective effect…
- Trial name
- NCT03068689
- Testing
- RIPC
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Subcutaneous Emphysema
SurgiQuest AirSeal in Robotic Partial Nephrectomy - (TARPAN Study)
A MULTI-CENTER, PROSPECTIVE, RANDOMIZED, CONTROLLED STUDY TO EVALUATE PHYSICIAN PREFERENCE RELATED TO THE USE OF THE SURGIQUEST AIRSEAL INSUFFLATION SYSTEM (AIS) VS.
- Trial name
- TARPAN (NCT02262884)
- Testing
- SurgiQuest AirSeal Insufflation System (AIS), Conventional Insufflation System (CIS)
- Where
- 3 sites in United States
- Volunteers
- 189 people
- Sponsor
- SurgiQuest, Inc.
Renal Cell Carcinoma
Robotic-assisted vs. Open Partial Nephrectomy
ROBOCOP is an open-label, randomized controlled feasibility trial comparing robotic-assisted and open partial nephrectomy in preparation for a confirmative phase III randomized controlled trial.
- Trial name
- ROBOCOP (NCT04534998)
- Testing
- Partial nephrectomy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Universitätsmedizin Mannheim
Renal Cell Carcinoma
The Evaluation of Functional Parenchymal Volume and Split Renal Function Before and After Partial Nephrectomy
The study aims to compare pre- and postoperative 3D renal function results of patients who underwent on-clamp and off-clamp partial nephrectomy.
- Trial name
- NCT04798963
- Testing
- On-clamp partial nephrectomy, Off-clamp partial nephrectomy
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Liver and Kidney Tumours
Thermal Ablation in Larger Liver and Kidney Tumours
This is a clinical research study designed to determine the safety and efficacy of the application of a unique interstitial radio frequency thermal therapy for the treatment of large tumours in the kidney or liver.
- Trial name
- NCT01720706
- Testing
- RFA Loosely wound thermal coil
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
Kidney Cancer, Prostate Cancer
Effect of Perioperative Intravenous Lidocaine Infusion in Robotic-Assisted Urologic Surgery
Controlling pain is fundamental during and after surgical procedures. This study examines pain associated with robotic assisted surgery on prostate cancer or a kidney mass.
- Trial name
- NCT03824808
- Testing
- Lidocaine Hydrochloride 0.8% in Dextrose 5% Solution, 0.9% Sodium Chloride Injection
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Missouri-Columbia
Kidney Tumor
Virtual Interactive 3D Modelling to Improve Outcomes in Robotic-Assisted Partial Nephrectomy
The primary objective is to determine if 3D modelling shortens total console operation time as a surrogate endpoint for clinical outcomes like perioperative complications and morbidity in robotic-assisted partial nephrectomy.
- Trial name
- 3DPN (NCT06056505)
- Testing
- partial kidney nephrectomy, DaVinci Robot, Innersight 3D software
- Where
- 10 sites in Germany
- Volunteers
- 370 people
- Sponsor
- University of Leipzig
Cancer of Kidney
Microwave Coagulation in Partial Nephrectomy Protocol
Partial nephrectomy (kidney removal) is a standard therapy for clinical T1 renal (kidney) tumors. The goals of surgery are to accurately remove the tumor with no cancer cells at the edge of the remaining tissue, to limit blood…
- Trial name
- NCT01931462
- Testing
- Microwave pre-coagulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Wisconsin, Madison