Clinical trials: Partial Rotator Cuff Tears, active
Rotator Cuff Tear, Rotator Cuff Syndrome
Lyophilized Platelet-Rich Plasma Lysate vs Dextrose Prolotherapy for Partial Rotator Cuff Tears
The goal of this clinical trial is to learn whether lyophilized platelet-rich plasma (PRP) lysate can improve shoulder symptoms, shoulder muscle strength, and tendon tear size in adults with partial-thickness rotator cuff tears…
- Conditions
- Rotator Cuff Tear, Rotator Cuff Syndrome, Rotator Cuff Arthropathy of Right Shoulder, Rotator Cuff Arthropathy of Left Shoulder
- Trial name
- NCT07789951
- Testing
- PRP lysate, Hypertonic dextrose
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- Taichung Veterans General Hospital
Rotator Cuff Injuries
Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears
The purpose of the study is to assess whether the REGENETEN™ Bioinductive Implant allows patients to get back to their everyday activities quicker than if the tendon is repaired by the standard repair technique 'Completion and…
- Trial name
- IMPACT (NCT05444465)
- Testing
- Isolated Bioinductive Repair, Completion and Repair
- Where
- 20 sites in United States, Australia and 4 more
- Volunteers
- 234 people
- Sponsor
- Smith & Nephew, Inc.
Partial Supraspinatus Tear, Rotator Cuff Tears (RCTs)
Platelet-Rich Plasma for Partial Rotator Cuff Tears
The goal of this clinical trial is to learn whether platelet-rich plasma (PRP) injection, made from a participant's own blood, can help heal the tendon and improve shoulder symptoms in people with partial tears of the…
- Conditions
- Partial Supraspinatus Tear, Rotator Cuff Tears (RCTs), Rotator Cuff Injury
- Trial name
- OPTIMISE (NCT07659600)
- Testing
- Platelet-Rich Plasma (PRP) Injections
- Volunteers
- 100 people
- Sponsor
- Universidade Nova de Lisboa
Supraspinatus Tear
Novel Treatment for Rotator Cuff Tears
The focus of this study is to examine changes in pain scores, strength, and range of motion over time following an ultrasonic tenotomy on a partial tear (<50%) of the supraspinatus tendon of the rotator cuff.
- Trial name
- NCT05590494
- Testing
- Ultrasonic tenotomy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Rotator Cuff Tear, Rotator Cuff Tendinitis
Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears
The purpose of this investigation is to evaluate the safety and superior effectiveness in functional improvement in patients with partial-thickness rotator cuff tears (PTRCTs) after the administration of a single injection of…
- Trial name
- NCT03752827
- Testing
- Adipose Derived Regenerative Cells, Corticosteroid
- Where
- 14 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- InGeneron, Inc.
Partial Thickness Rotator Cuff Tear
A Phase 2b/3 Study of TPX-115 on Partial-thickness Rotator Cuff Tear
Rotator cuff tear is one of the most common shoulder diseases and conservative treatment is commonly used for tears involving ≤50% of tendon thickness.
- Trial name
- NCT06414005
- Testing
- TPX-115
- Where
- 2 sites in South Korea
- Volunteers
- 166 people
- Sponsor
- Tego Science, Inc.
Partial Rotator Cuff Tears, Rotator Cuff Injuries
Concentric vs Eccentric Full Can Exercise in Partial Rotator Cuff Tears
This study aims to compare the effects of concentric and eccentric full can exercises on supraspinatus muscle architecture in individuals with partial rotator cuff tears.
- Conditions
- Partial Rotator Cuff Tears, Rotator Cuff Injuries, Shoulder Pain Syndrome
- Trial name
- FULLCAN-PRCT (NCT07587931)
- Testing
- Concentric Full Can Exercise, Eccentric Full Can Exercise, Standard Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Firat University
Rotator Cuff Tears
Effect of Central Sensitization on Response to Physical Therapy in Patients With Partial Supraspinatus Tear
This prospective observational study aims to investigate whether central sensitization influences the response to physical therapy in patients with partial supraspinatus tendon tears.
- Trial name
- NCT07664137
- Testing
- Standard Physical Therapy and Rehabilitation
- Volunteers
- 60 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Massive Rotator Cuff Tear
Effects Of Biceps Transposition Without Tenotomy For Augmentation Of Massive Rotator Cuff Repairs
This prospective, single-arm interventional study will evaluate the effects of long head of the biceps tendon (LHBT) transposition without tenotomy as an augmentation technique for arthroscopic partial repair in adults with…
- Trial name
- ROTATORCUFF (NCT07375277)
- Testing
- LHBT Transposition Augmentation
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Balikesir Ataturk City Hospital
Partial Rotator Cuff Tears (PRCTs)
High-frequency Short-course Extracorporeal Shock Wave Therapy for Partial Rotator Cuff Tears: Study Protocol for a Multicenter, Randomized, Controlled Trial
This is a multicenter, randomized controlled clinical study exploring three different extracorporeal shock wave therapy (ESWT) regimens for patients with partial rotator cuff tears, a common cause of chronic shoulder pain and…
- Trial name
- NCT07673055
- Testing
- Arm 1 Intervention Name: High-frequency short-course extracorporeal shock wave therapy Arm 2 Intervention Name: High-frequency intensive extracorporeal shock wave therapy Arm 3 Intervention Name: Conv
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Rotator Cuff Disease
Umbilical Cord-derived Mesenchymal Stem Cell Injectables for the Regeneration of Partial-thickness Rotator Cuff Tears
The purpose of this study is to evaluate umbilical cord-derived mesenchymal stem cell injectables for the regeneration of partial-thickness rotator cuff tears
- Trial name
- NCT07605559
- Testing
- umbilical cord-derived mesenchymal stem cell, Normal Saline
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Kyoung Hwan Koh
Partial Rotator Cuff Tears
Effect of Perturbation Exercise Protocol in Patients With Partial Rotator Cuff Tear: A Single-Blind Randomized Controlled Trial
Partial rotator cuff tears negatively affect shoulder stability, proprioception, and neuromuscular control. Perturbation-based rehabilitation has been shown to enhance reflex muscle activation and dynamic joint stabilization…
- Trial name
- NCT07482735
- Testing
- Conventional physiotherapy, Perturbation exercise protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Rotator Cuff Tears, Rotator Cuff Injuries
Arthroscopic Rotator Cuff Repair With Long Head of Biceps Transposition and Acellular Dermal Matrix Augmentation for Large to Massive Incompletely Repairable Rotator Cuff Tears
Large-to-massive rotator cuff tears of the shoulder with poor tendon and muscle quality often cannot be fully repaired back to its footprint, and they have a high risk of re-tear.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Massive Rotator Cuff Tear
- Trial name
- SCR-ADM-repair (NCT07875556)
- Testing
- Rotator Cuff Repair, Long Head of the Biceps Tendon Transposition, Acellular Dermal Matrix (Allograft) Augmentation
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Tam Anh Research Institute
Partial Rotator Cuff Tears, Rotator Cuff Tendinopathy
Intralesional Versus Perilesional 5% Dextrose Injection in Partial Rotator Cuff Tears
This prospective, randomized, double-blind controlled clinical trial aims to compare the clinical and ultrasonographic outcomes of intralesional and perilesional 5% dextrose injection in patients with partial rotator cuff tears.
- Conditions
- Partial Rotator Cuff Tears, Rotator Cuff Tendinopathy, Shoulder Pain Chronic, Supraspinatus Tendon Tear
- Trial name
- NCT07688902
- Testing
- Intralesional 5% Dextrose Injection, Perilesional 5% Dextrose Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara City Hospital Bilkent
Partial Thickness Rotator Cuff Tears
Efficacy and Safety Study of TPX-115 on Partial-thickness Rotator Cuff Tear
The goal of this study is to evaluate the efficacy and safety of allogeneic dermal fibroblasts (TPX-115) compared to placebo in patients with Partial-Thickness Rotator Cuff Tear(PTRCT).
- Trial name
- NCT07219654
- Testing
- TPX-115, Cryopreserving hyaluronic acid medium, Saline
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Tego Science, Inc.
Rotator Cuff Tear
Superior Capsular Reconstruction vs. Partial Repair for Massive Rotator Cuff Tears
Little evidence exists to guide treatment in patients with massive irreparable rotator cuff tears (MRCTS). Arthroscopic partial rotator cuff repair (PRCR) has the longest record of use.
- Trial name
- SCR (NCT03617562)
- Testing
- Superior Capsular Reconstruction, Partial Repair
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Sunnybrook Health Sciences Centre
High-grade Partial or Full Thickness Rotator Cuff Tears
Cold and Compression After Rotator Cuff Repair (RCR)
The purpose of this study is to compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and cold/compression groups pre-surgically, daily after surgery for 14…
- Trial name
- NCT07516327
- Testing
- SOC (Standard of care), Cold and Compression
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ochsner Health System
Partial Thickness Rotator Cuff Tear
A Longitudinal, Multi-Center Safety Study of Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears
This is a longitudinal follow-up study of the RC-002 study, in which up to 246 subjects assigned to two randomization arms will be enrolled: an adipose-derived regenerative cell (ADRC) injection arm (ADRC treatment arm) and the…
- Trial name
- NCT05400798
- Testing
- Adipose Derived Regenerative Cells, Corticosteroid
- Where
- 11 sites in United States
- Volunteers
- 246 people
- Sponsor
- InGeneron, Inc.
Rotator Cuff Tears
Effect of Motor Imagery Training on Pain, Functionality, Proprioception and Kinesiophobia in Partial Rotator Cuff Tear
The aim of this study is to investigate the effects of motor imagery training on pain, functionality, proprioception and kinesiophobia in patients with partial rotator cuff tears.
- Trial name
- NCT06875895
- Testing
- Traditional Physiotherapy, Motor Imagery Training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kutahya Health Sciences University
Rotator Cuff Injuries
Evaluation Of Outcomes Following Rotator Cuff Repair Using the REGENETEN Bioinductive Implant
This prospective, single-arm, multicenter registry is being conducted to collect real world post-market data from patients who are undergoing rotator cuff repair using the REGENETEN◊ Bioinductive Implant System.
- Trial name
- RePaRe (NCT06857084)
- Testing
- Arthroscopic rotator cuff repair with REGENETEN Bioinductive Implant augmentation
- Where
- 22 sites in Australia, Germany and 2 more
- Volunteers
- 400 people
- Sponsor
- Smith & Nephew, Inc.