Clinical trials: Partial-thickness Burn Wounds
Acute Deep Partial Thickness Thermal Burns
Applying Platelet Rich Plasma (PRP) Gel to Acute Deep Partial Thickness Thermal Injuries
The study will examine the safety of using a concentration of proteins from a patient's own blood, referred to as platelet rich plasma or (PRP) and applying it to a second degree burn wound.
- Trial name
- NCT02169362
- Testing
- Autologous Platelet Rich Plasma (PRP) Gel (Magellan® Bio-Bandage™)
- Where
- 8 sites in United States
- Volunteers
- 36 people
- Sponsor
- Arteriocyte, Inc.
Burns
Medihoney and Santyl for Burn Injuries
This study is designed to assess the efficacy of MEDIHONEY® Gel with Active leptospermum honey dressing relative to SANTYL® ointment dressing on time to heal, bacterial growth in the wound, patient satisfaction, and treatment…
- Trial name
- MSBI (NCT02250183)
- Testing
- MEDIHONEY® GEL WITH ACTIVE LEPTOSPERMUM HONEY, Santyl
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Skin Wound, Burns
StrataGraft Safety, Tolerability and Efficacy in Pediatric Subjects
Autografting is a surgical procedure to transplant healthy skin (donor skin) from another part of the participant's own body (donor site) to the burned part. Autografting is the usual treatment for DPT burns.
- Conditions
- Skin Wound, Burns, Trauma-related Wound
- Trial name
- StrataSTEPS (NCT05517902)
- Testing
- StrataGraft
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Skin Burn Degree Second
Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds
The purpose of this study is to determine the extent to which Keramatrix dressing promotes the healing of second-degree burn wounds in pediatric patients.
- Trial name
- NCT01790763
- Testing
- Keramatrix, Mepilex
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Burn
Use of Amnion on Partial Thickness Burns
To determine if Amnion, used on partial thickness burn injuries would provide an improvement in rate of healing, pain control and scarring as compared to standard medical treatments.
- Trial name
- Amnion (NCT00674999)
- Testing
- Amnion, Polysporin/Bacitracin/Mycostatin
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns, Electrical Burn
The Treatment Challenges and Limitation in High-Voltage Pediatric Electrical Burn at Rural Area
A case of high-voltage pediatric electrical burn involving a fully conscious 13-year old boy who was admitted to the emergency room after being electrocuted by high-voltage power cable, with superficial partial thickness burn…
- Conditions
- Burns, Electrical Burn, Burn Degree Second, Burn Scar
- Trial name
- NCT04772573
- Where
- Indonesia
- Volunteers
- 1 people
- Sponsor
- S.K. Lerik General Hospital
Burns, Burn Degree Second
A Study to Evaluate the Safety, Tolerability and Efficacy in Patients With Burn(s)
For Phase 1, researchers will explore the safety, and tolerability of PMS-101 and determine the recommended Phase 2 dose (RP2D) using the donor site.
- Trial name
- NCT06440239
- Testing
- PMS-101, Standard treatment
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Primoris Therapeutics
Burns
Oleogel-S10 Versus Standard of Care in Healing of Grade 2a Burn Wounds
The main goal of this phase III clinical trial is to show safety and efficacy of Oleogel-S10 in the acceleration of wound healing of grade 2a burn wounds.
- Trial name
- NCT01657292
- Testing
- Oleogel-S10 ointment, Octenilin® wound gel
- Where
- 9 sites in Germany, Sweden and 2 more
- Volunteers
- 61 people
- Sponsor
- Birken AG
Burns
Pediatric Burn Treatment Using Tilapia Skin as a Xenograft for Superficial-Partial Thickness Wounds
This study aims to evaluate the efficacy of Nile tilapia skin as a xenograft for the treatment of partial-thickness burn wounds in children.
- Trial name
- NCT04391582
- Testing
- Tilapia skin, silver sulfadiazine cream 1%
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
Thermal Burn
Safety and Feasibility of ADRCs Treatment To Patients With Thermal Wounds
The primary objective of the protocol is to evaluate preliminary safety and feasibility of ADRCs via intravenous delivery in the treatment of deep partial and full thickness thermal wounds.
- Trial name
- NCT03435172
- Testing
- Device-ADRCs intravenously infusion
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Cytori Therapeutics
Burn Degree Second, Burn Degree Third
Biological Skin Graft With Keratinocyte-stem Cell Co-cultre for Burn Patients
The goal of this clinical trial is to test whether artificial skin graft can substitute autologous skin graft in current burn treatment.
- Trial name
- NCT05652816
- Testing
- Split-thickness skin graft, Artificial skin graft, Artificial skin graft co-culture
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Indonesia
Impact of ROM Exercises on Pain and Functional Ability in Patients With Second -Degree Burns
Impact of Range of Motion Exercises on Pain and Functional Ability
The goal of this quasi-experimental study is to evaluate the effect of range of motion (ROM) exercises on pain and functional ability among adult patients of both genders with second-degree burn injuries affecting the upper…
- Trial name
- ROM-SDB (NCT07883863)
- Testing
- Range of Motion exercises
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Second-degree Burn Wounds, Skin Graft Wounds
Efficacy of a Transparent Silicone Membrane With Physical Microstructure for Second-degree Burn Wounds and Skin Graft Wounds
The goal of this clinical trial is to comparison of physical microstructure-modified transparent silicone films and current conventional trauma dressings for second-degree burn wounds and post-skin graft wounds.The main question…
- Trial name
- NCT06170008
- Testing
- Physical microstructure-modified transparent silicone film sheet, Decellularized pig skin, Vaseline gauze
- Volunteers
- 40 people
- Sponsor
- Changhai Hospital
Burn Scar, Burns
Shock Wave Therapy Versus Conventional Physical Therapy for Partial- Thickness Forearm Burn Scars
Burn injuries can lead to significant physical and psychological challenges, particularly when they result in scarring. Burn scars can lead to a variety of complications that significantly impact a patient's quality of life1.
- Trial name
- NCT07234305
- Testing
- Shock wave, Traditional Physical Therapy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- MTI University
Burns, Second Degree Burn
4-Aminopyridine to Treat Skin Burns
Many patients suffer from traumatic burns and current treatments do not increase the regenerative potential of either skin grafts or the remaining uninjured skin.
- Conditions
- Burns, Second Degree Burn, Wounds and Injuries
- Trial name
- NCT06596434
- Testing
- Drug: 4-Aminopyridine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- John Elfar
Burns
Comparison of Wound Bed Establishment in Facial Burns
Forty percent of patients admitted to the contributing regional burn unit over a five month period received facial burns (n=14).
- Trial name
- NCT01668030
- Testing
- Enzymatic agent, Bacitracin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Louisville
Burn
A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-BI-101 Clinical Trial
This is an open-label follow up study to evaluate the safety for the subjects with ALLO-ASC-DFU treatment in phase 1 clinical trial(ALLO-ASC-BI-101) for 23 months.
- Trial name
- NCT03183622
- Testing
- ALLO-ASC-DFU
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Anterogen Co., Ltd.
Burns
The Effect of Two Versus Ten Days Application of Flammacerium in Partial Thickness Burns
The objective of the proposed study is to assess whether the application of flammacerium for 2 days is as good as, or even better than, the application of flammacerium for 10 days regarding woundhealing in partial thickness burns.
- Trial name
- NCT00156988
- Testing
- cerium nitrate-silver sulfadiazine (cerium-flamazine)
- Where
- Netherlands
- Sponsor
- Association of Dutch Burn Centres
Burn Wound and Skin Graft Healing
Healing of Burns and the Effect of Shockwave Therapy on the Recovery of Skin Grafts
The study is to review whether musculoskeletal shockwave therapy (ESWT) can speed up the healing of second-degree burns as well as skin-graft donor sites.
- Trial name
- NCT01242423
- Testing
- extracorporeal shockwave therapy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Unfallkrankenhaus Berlin
Burn Degree Second, Burn Degree Third
The Effect of Reflexology Massage and Passive Music Therapy Intervention Before Burn Dressing
Reflexology massage applied before burn dressing reduces pain, anxiety and sleep problems
- Trial name
- NCT04200053
- Testing
- Reflexology massage, Reflexology massage and passive music
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi