Clinical trials: Particulate Matter
Blood Pressure, Lung Function
The Use of Air Cleaners to Mitigate Cardiopulmonary Health Impact of Indoor Exposure to Particles and Phthalates
This study aims to evaluate whether a short-term intervention strategy using air cleaner reduces indoor exposure to airborne particles (particulate matter with an aerodynamic diameter ≤2.5μm, PM2.5) and phthalates and improves…
- Conditions
- Blood Pressure, Lung Function, Inflammation, Oxidative Stress
- Trial name
- NCT03500614
- Testing
- Air cleaner use method 1, Air cleaner use method 2
- Where
- China
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Peking University
Asthma
Asthma & Exposure to Peaks in Particulate Air Pollution
We are testing the following two hypotheses: 1) Peaks in hourly exposures to airborne particulate matter (PM) of outdoor origin will be more closely associated with acute asthmatic responses to particles than 24-hour average…
- Trial name
- NCT00013728
- Volunteers
- 24 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Childhood Asthma
A Community-based Participatory Research (CBPR) Intervention for Childhood Asthma Using Air Filters and Air Conditioners
The burden of childhood asthma is borne disproportionately by children living in poverty and in urban centers, many of whom are from communities of color and are at greater risk for environmental exposures.
- Trial name
- CAAA (NCT00839046)
- Testing
- Community Health Worker Intervention, Air Filter, Air Filter and Air Conditioner
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Michigan
Cardiovascular Diseases (CVD), Metabolic Syndrome
Ambient Air and Noise Effect on Cardiovascular Health Risk and Lifestyle Intervention to Attenuate It (METSGREEN)
This study, combining both an observational study and an interventional clinical trial, aims to assess how exposure to ultrafine particulate matter (PM0.1) and noise pollution affects the risk of cardiovascular diseases and…
- Conditions
- Cardiovascular Diseases (CVD), Metabolic Syndrome, Air Pollution Exposure, Environmental Exposure
- Trial name
- METSGREEN (NCT07111208)
- Testing
- Green Space Activity Group - Daily Physical Activity, Mediterranean Diet Group - Dietary Intervention
- Where
- 2 sites in Lithuania
- Volunteers
- 180 people
- Sponsor
- Regina Grazuleviciene
Inadequate or Impaired Respiratory Function
The Differential Pattern of Deposition of Nano Particles in the Airways of Exposed Workers
Investigation of the differences between the levels of extracellular and intracellular nano-particles in workers exposed to environmental particles during their employment to enhance understanding the process of penetration of…
- Trial name
- Nanoexposure (NCT01599845)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pregnant Women
Impact of UFPs and MNPs on Fetal Health
This project aims at unravelling mechanisms by which exposure to air pollution (in particular Ultrafine Particulate (UFP, PM0.1), and micro nano plastic's) interferes with the normal foetus development, with a short-term causal…
- Trial name
- UPRISE (NCT07238608)
- Where
- Spain
- Volunteers
- 1,600 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Asthma in Children
Home Air in Agriculture: Pediatric Intervention Trial
This study seeks to reduce exposure to asthmagens in the homes of a community of Latino children residing in an area of intense agricultural production in Eastern Washington by testing the effectiveness of an intervention (high…
- Trial name
- HAPI (NCT04919915)
- Testing
- HEPA air cleaner
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Washington
Asthma in Children, Pollution; Exposure
AIM to Improve Asthma: Airflow Improvements During Meal-Prep
The investigators propose a pilot trial of kitchen ventilation in the homes of children using a youth engaged research strategy.
- Trial name
- AIM (NCT04464720)
- Testing
- Cooking Ventilation Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Berkeley
Acute Coronary Syndrome, Heart Failure
Effect of Air Pollution in the Haifa Bay Area on Cardiovascular Morbidity and Mortality
The association between exposure to ambient air pollution and pulmonary disease has been well established.To date no study has assessed the burden of cardiovascular disease in Israel and its relation to ambient air pollution.
- Conditions
- Acute Coronary Syndrome, Heart Failure, Arrhythmia
- Trial name
- NCT01325155
- Volunteers
- 5,000 people
- Sponsor
- Rambam Health Care Campus
Cognitive Function, Cardiopulmonary Function
Commuter Air Pollution Intervention Study
Traffic related air pollution is a well-recognised and much studied contributor to smog and is linked to a number of adverse health outcomes.
- Conditions
- Cognitive Function, Cardiopulmonary Function, Saliva Stress Hormones, Air Pollution Exposure
- Trial name
- CAPI (NCT02277002)
- Testing
- Cabin Air Filtration
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Health Canada
Behavior Change
Evaluation of Report-Back Strategies for Long-term and Short-term Exposure Information in Rural Tribal Populations
The goal of this study is to evaluate different ways to provide feedback about environmental sampling results to participants. Specifically, the study will look at exposures with long-term risk (radon) and short-term risk (indoor…
- Trial name
- NCT06593340
- Testing
- Messenger 1, Messenger 2, Format 1
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Utah
COPD, Particulate Matter Induced Inflammation of the Lung
Efficacy and Feasibility of Ectoin® Inhalation Solution in Inflammatory Obstruction and Ageing of the Lung
To investigate the physical inflammation inhibition effects of EIL (Ectoin-Hydro-Complex) in subjects of the established SALIA-cohort and the preventive effects on lung function decline.
- Trial name
- EFECT (NCT01225965)
- Testing
- Ectoin Inhalation Solution
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Bitop AG
Pneumococcal Carriage, Particulate Matter
Indoor Air Pollution (IAP) Carriage Study
Personal exposure to Indoor Air Pollution (IAP) is a known risk factor of severe pneumonia, which is the number one killer of children under five in developing countries.
- Trial name
- NCT01660659
- Testing
- Biomass Briquettes and Rocket stove
- Where
- The Gambia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Pregnancy, Preeclampsia
Impact of Particulate Matter on Mothers and Babies in Antwerp (IPANEMA)
Introduction: An emerging body of evidence indicates that there is an association between air pollution exposure in pregnancy and adverse pregnancy outcomes (Rudra, Williams, Sheppard , Koenig, \& Schiff, 2011; Dadvand, et al.…
- Trial name
- IPANEMA (NCT02592005)
- Testing
- amount of fine dust and other environmental exposure
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Cardiopulmonary Function, Child
Health Benefits of Air Purifiers in Primary School Students
This study aims to explore changes in cardiopulmonary function and other health indicators in primary school students with the intervention of air purifiers on a randomized controlled trial.
- Trial name
- NCT05016271
- Testing
- Air purifier and fresh air ventilation systems with high-efficiency particulate air (HEPA) filters, Air purifier and fresh air ventilation systems without high-efficiency particulate air (HEPA) filters
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Fudan University
Autonomic Nervous System Imbalance, Blood Pressure
Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators
An intervention study to assess the short-term cardiovascular effects of reducing personal air pollution exposure by wearing particulate filtering respirators.
- Conditions
- Autonomic Nervous System Imbalance, Blood Pressure, Inflammation, Vasoconstriction
- Trial name
- NCT02238028
- Testing
- Wear respirator
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Fudan University
Cardiometabolic Health
Reducing Particulate Matter-associated Cardiovascular Health Effects for Seniors
Exposure to fine particulate matter (PM2.5) air pollution is an established risk factor for cardiovascular (CV) morbidity.
- Trial name
- RAPIDS2-Ypsi (NCT04103346)
- Testing
- air filtration with air purifier with hepa filter
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cardiorespiratory and Vascular Dysfunction, Obstructive Airway Disease
World Trade Center Particulate Matter Induced Cardiorespiratory and Vascular Dysfunction: a MultiOmic Approach (CaRVD)
Particulate matter (PM) associated cardiorespiratory and vascular dysfunction (CaRVD) poses a significant global health burden. The World Trade Center (WTC) destruction on September 11, 2001 led to an intense deposition of…
- Trial name
- NCT05215171
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Allergic Rhinitis
Controlled Exposure to Diesel Exhaust in Subjects With Allergic Rhinitis
Proximity to traffic, particularly to diesel-powered heavy-duty vehicles, has been associated with inducing and enhancing allergies in children and adults.
- Trial name
- DALLER (NCT01617330)
- Testing
- Bronchoscopy
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- University Hospital, Umeå
Air Pollution
Particulate Matter, Blood Pressure, and the Sympathetic Nervous System
Healthy volunteers will be exposed to ambient air near a roadway under the conditions of with and without a facemask and their responses will be evaluated.
- Trial name
- PM-SNS (NCT03079843)
- Testing
- exposure to particulate matter with N 95 facemask, exposure to particulate matter with no face mask
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan