Clinical trials: Parturition
Premature Birth
Cerclage On LOw Risk Singletons: Cervical Cerclage for Prevention of Spontaneous Preterm Birth in Low Risk Singleton Pregnancies With Short Cervix
The aim of this study is to evaluate the efficacy of cervical cerclage in prevention of spontaneous preterm birth in singleton pregnancies with a short transvaginal cervical length (<=25mm) and without prior spontaneous preterm…
- Trial name
- COLORS (NCT03251729)
- Testing
- Cervical cerclage, Vaginal progesterone
- Where
- 3 sites in United States, Italy
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Pain
Does a Perioperative Course of Gabapentin Improve Analgesia After Cesarean Delivery?
Gabapentin has been very effective at treating pain after knee and hip operations, hysterectomies, and many other types of operations.
- Trial name
- NCT01848119
- Testing
- Gabapentin, lactose
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Premature Birth of Newborn
Skin Maturation in Premature Infants
The skin barrier lipids will be lower in premature infants than in full term infants and will become normal over 3-4 months after birth.
- Trial name
- NCT01619228
- Where
- 2 sites in United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Labor, Pregnancy
The Effects of Warm Showers Application in Birth on Birth Pain, Birth Satisfaction and Birth Results
The use of non-pharmacological methods in labor pain is very important in order to improve the birth process, increase comfort and provide relaxation.
- Conditions
- Labor, Pregnancy, First Stage of Labor
- Trial name
- NCT05335681
- Testing
- Warm Showers Application
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Caesarean Section, Pregnant Women
Effects of Acupressure Applied Before Cesarean Delivery on Anxiety, Physiological Parameters and Fetal Heart Rate
Cesarean section is the most commonly preferred surgical method in cases where vaginal birth is not possible or complications that may endanger the health of the mother and baby occur.
- Conditions
- Caesarean Section, Pregnant Women, Anxiety Disorder
- Trial name
- NCT06953037
- Testing
- acupressure
- Where
- 2 sites in Cyprus
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Labor Pain
Parturient Controlled Epidural Analgesia (PCEA) With or Without a Basal Infusion for Early Labor
Patient Controlled Epidural Analgesia is a widely used and effective means of adult pain management. However, Parturient Controlled Epidural Analgesia (PCEA) is a relatively new approach to pain control for the women in labor.
- Trial name
- NCT00871442
- Testing
- No Basal Infusion, Basal infusion, PCEA solution (bupivacaine and fentanyl)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neil Roy Connelly, MD
Skin Irritation, Sensitization
A Skin Irritation Assessment of Once-Weekly Corplex™ Donepezil Transdermal Delivery System
A study to assess the skin irritation and sensitization potential of Corplex™ Donepezil Transdermal Delivery System (TDS)
- Trial name
- NCT03397862
- Testing
- Donepezil TDS, Vehicle TDS
- Where
- 2 sites in United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Corium, Inc.
Opioid Use, Unspecified
Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery
This is a randomized controlled trial assessing the utility of an educational video on pain management after a cesarean section to reduce opioid use.
- Trial name
- NCT03959969
- Testing
- Educational video, Standard of care, Ibuprofen
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Fetal Macrosomia, Abdominal Wall Mass
Fetal Front-abdominal Wall Thickness and Perinatal Outcome
Abnormal fetal development such as macrosomia can cause some complications on both fetus and mother.The measurement of fetal anterior abdominal wall thickness (FAWT) is an easy examination that it can be obtained during an…
- Conditions
- Fetal Macrosomia, Abdominal Wall Mass, Perinatal Problems
- Trial name
- NCT03232294
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Hyperfibrinolysis, Cesarean Section Complications
The Incidence of Hyperfibrinolysis During Vaginal Delivery and Cesarean Section
This study aims to find out if there are common major changes in coagulation immediately after delivery of the newborn during Cesarean (C) -section and vaginal birth.
- Conditions
- Hyperfibrinolysis, Cesarean Section Complications, Coagulation Defect; Bleeding, Peripartum Haemorrhage
- Trial name
- NCT05975112
- Testing
- Coagulation tests (TEG, Levels of F1, F2, hs-D-dimer, Plasminogen, PAI 1+2), SpHb before discharge
- Where
- Austria
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Painless Vainal Labour
DEXMEDETOMIDINE in NORMAL VAGINAL DELIVERY
compare the effect of intravenous and epidural dexmetomidine as an adjuvant to local anesthetics in epidural labor analgesia in normal labor
- Trial name
- NCT05840328
- Testing
- Dexmedetomidine Injection [Precedex], Bupivacaine Injection
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Antenatal Care and Delivery
Increasing Women's Access to Skilled Pregnancy Care to Reduce Maternal Mortality in Nigeria
Background: Nigeria has the second highest absolute number of maternal deaths and perinatal deaths in the world. The country contributes 14% of all maternal deaths worldwide, second only to India.
- Trial name
- NCT02643953
- Testing
- Incentives, Community
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Vaccine Refusal, Covid19
Project 2VIDA! COVID-19 Vaccine Intervention Delivery for Adults in Southern California
The United States (U.S.) is the country with the largest number of infections and deaths due to COVID- 19 and racial/ethnic minorities are disproportionately affected.
- Trial name
- 2VIDA! (NCT05022472)
- Testing
- COVID-19 Individual Awareness and Education., COVID-19 Community Outreach & Health Promotion., COVID-19 Individual Health Education & Linkages to Medical and Supportive Services.
- Where
- 6 sites in United States
- Volunteers
- 1,051 people, healthy volunteers welcome
- Sponsor
- Britt Skaathun
Temperature Regulation; Disorder, Fetus or Newborn
Effect of Drying Before Plastic Wrapping on Thermal Losses in Very Preterm Infants at Birth
This is a multicenter, unblinded, randomized controlled trial comparing drying vs. not drying before plastic wrapping for the thermoregulation of very preterm infants at birth.
- Trial name
- NEODRY (NCT05740072)
- Testing
- Drying before wrapping, No drying before wrapping
- Where
- Italy
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Dental Phobia, Dental Anxiety
"Study of Pain Perception Using Computer-Controlled Versus Conventional Local Anaesthesia in Children Undergoing Molar Extraction
This clinical trial aims to compare pain perception in children during dental procedures when using a computer-controlled local anesthesia device versus a traditional syringe.
- Conditions
- Dental Phobia, Dental Anxiety, Dental Anesthesia, Dental Anesthesia Efficacy
- Trial name
- CCLAD-Pain (NCT07056101)
- Testing
- A conventional dental syringe, GENI High-Speed Injection, GENI Moderate-Speed Injection
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tarek MHD kher al saka amini
Anemia of Prematurity, Very Low Birth Weight Infant
Iron Supplementation and Intestinal Health
This is a randomized double-blinded study of enteral iron supplementation in Very Low Birth Weight infants. The subjects will be randomized into low dose (2 mg/kg/day) and high dose (6 mg/kg/day) of daily iron supplementation.
- Trial name
- NCT04497012
- Testing
- 2mg/kg/day Iron Sulfate, 6 mg/kg/day Iron Sulfate
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Preterm Birth
Interdisciplinary E-health Based Follow-up of Preterm Born Children
The aim of the study is to assess mental and somatic symptoms of preterm born children at the ages of 2, 5 and 10 by a multidisciplinary team and to evaluate an app that screens for these symptoms.
- Trial name
- NeoUp (NCT06345664)
- Testing
- Diagnostics and intervention recommendations
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Insulin Dependent Diabetes Mellitus, Feeding and Eating Disorders
The diabEAT Study: Insulin dElivery Technologies And eaTing Behaviours in People With Type 1 Diabetes
Type 1 diabetes is an autoimmune health condition that requires daily injections of insulin. Insulin allows the body to use energy from carbohydrates in food.
- Conditions
- Insulin Dependent Diabetes Mellitus, Feeding and Eating Disorders, Eating Behavior, Type 1 Diabetes
- Trial name
- NCT07348432
- Testing
- Automated Insulin Delivery (AID) Systems, Carbohydrate Counting Inaccuracy Percentage
- Where
- Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- McGill University
Contraception
Home or Office Visit for the Insertion of Implantable Birth Control
This is a pilot study in which women who desire an etonogestrel implant will be randomized to either a home or office insertion visit.
- Trial name
- NCT01816932
- Testing
- Home Visit, Office visit
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
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