Clinical trials: Parturition
Infant, Newborn, Infant, Low Birth Weight
Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia
This study tested whether Neonatal Intensive Care Unit (NICU) teams trained in benchmarking -- comparing care practices between different NICUs to see which practices prevent bronchopulmonary dysplasia (BPD) -- and quality…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- Benchmarking (NCT00067613)
- Testing
- Benchmarking Management Practices, Standard Management Practices
- Where
- 17 sites in United States
- Volunteers
- 4,095 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
HIV/AIDS, Infant Morbidity
Assessing the Feasibility, Acceptability and Effects Of HIV Birth Testing In Maternity Settings In Zimbabwe
This study aims to assess the feasibility and, acceptability and effects of implementing HIV testing at birth testing using point-of-care (POC) HIV nucleic acid testing (NAT) in maternity settings.
- Conditions
- HIV/AIDS, Infant Morbidity, Perinatal HIV Infection, HIV Infections
- Trial name
- NCT04206241
- Testing
- Point of care early infant diagnosis (POC EID)
- Where
- 10 sites in Zimbabwe
- Volunteers
- 278,833 people, healthy volunteers welcome
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Overconsumption, Obesity
Nutri-score Labels on the Nutritional Quality of Out-of-home Food Selection
Participants will be asked to make hypothetical food choices in an online simulation study of an OOH delivery app. This study will be a three-arm randomised controlled design, with intervention type as the 3-level grouping…
- Trial name
- NCT07423845
- Testing
- Labelling condition - Calorie labelling, Labelling condition - Nutri-score labelling, Labelling condition: Nutri-score labelling + educational intervention
- Where
- United Kingdom
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Caesarean Section, Mother-Child Relations
Effect of Mother's Push at Cesarean Delivery Mother's PUSHING AT CS A RANDOMIZED CONTROLLED TRIAL
The purpose of this study is to assess the safety and efficacy of the mother's active pushing during cesarean delivery.
- Conditions
- Caesarean Section, Mother-Child Relations, Post Operative Pain, Postpartum Depression
- Trial name
- NCT05520580
- Testing
- Mother's push during CS
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Preeclampsia, Preterm Birth
Biobank on Prematurity, Preeclampsia and Other Pregnancy Complications
The Biobank includes data and biological specimens of women from three original studies: 1) First-trimester Prediction of Preeclampsia (PREDICTION Study, NCT02189148), 2) Pre-Eclampsia And growth Retardation, an evaluative…
- Conditions
- Preeclampsia, Preterm Birth, Pregnancy Complications, Fetal Anomalies
- Trial name
- NCT02744365
- Testing
- Observational
- Where
- Canada
- Volunteers
- 7,845 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Mindfulness, Pregnancy
The Effect of Mindfulness-Based Pregnancy Education Program on Stress, Birth Fear and Birth Self-Efficacy in Pregnants
The research will be carried out to determine the effect of mindfulness-based pregnancy education program on stress, fear of childbirth and birth self-efficacy in pregnant women.
- Conditions
- Mindfulness, Pregnancy, Stress, Childbirth
- Trial name
- NCT05507307
- Testing
- mindfulness-based pregnancy education program.
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Inonu University
Induced Vaginal Delivery
Newborn Pain and Stress Levels in Oxytocin Induction at Birth
The aim of the study is to compare pain and stress levels in the early neonatal period in newborns with and without oxytocin induction. The research was conducted in a case-control study design.
- Trial name
- NCT06474000
- Testing
- Oxytocin induction group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Child Maltreatment, Domestic Violence
Efficacy of Group Attachment Based Intervention for Vulnerable Families
The study examines the effectiveness of parent-child Group Attachment Based Intervention (GABI) in reducing risk of maltreatment in infants and toddlers compared with parenting skills classes.
- Trial name
- NCT01641744
- Testing
- Systematic Training for Effective Parenting (STEP), Group Attachment Based Intervention (GABI)
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Fetal Distress, Perinatal Asphyxia
Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource Settings
The PRISM pilot feasibility study consists of two phases to determine: 1) to delivery practices, rates of primary and secondary outcomes, and feasibility of enrollment rates, and 2) to assess the feasibility and acceptability of…
- Conditions
- Fetal Distress, Perinatal Asphyxia, Birth Asphyxia, Stillbirth
- Trial name
- PRISM (NCT05946681)
- Where
- Zambia
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Contraception, Contraception Behavior
Birth Control to Improve Birth Spacing
This study aims to investigate the drivers of postpartum contraceptive use with a prospective cohort. The study will clarify the role of contraceptive knowledge, attitudes, norms, and self-efficacy in driving intention to…
- Conditions
- Contraception, Contraception Behavior, Knowledge, Attitudes, Practice, Birth Spacing
- Trial name
- BIBS (NCT05240066)
- Where
- 2 sites in United States
- Volunteers
- 1,341 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
COVID-19 Pneumonia, COVID-19 Pandemic
Corona Virus Disease 2019 Cohort Study
The goal of this observational study is to learn about the influence of Corona Virus Disease 2019 on obstetric outcome and offspring development.
- Conditions
- COVID-19 Pneumonia, COVID-19 Pandemic, COVID-19
- Trial name
- NCT06927622
- Where
- 5 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shandong University
Labour Pains, Massage
Effect of Nonpharmacological Methods on The Active Phase Of Labour
The aim of this clinical trial is to evaluate the effects of methods such as exercise and hot showers applied during the active phase of labour on labour pain, labour duration, mode of delivery, newborn health, and the labour…
- Conditions
- Labour Pains, Massage, Exercise
- Trial name
- EFPCMUAPLBO (NCT07060339)
- Testing
- Exercise Programme, Hot Shower Programme, Combined Application (Exercise + Hot Shower)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Prematurity, Neonatal Sepsis
Defects in Opsonophagocytosis in Premature Infants
The purpose of the study is to characterize innate immune function of premature infants, and identify defects that may be responsible for the development of bacterial sepsis.
- Trial name
- NCT00866567
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Breastfeeding, Prematurity
Facilitation and Barriers to Breastfeeding in the NICU
To date, there is a paucity of research focusing on maternal breastfeeding goals, how these goals may change after an unexpected event such as a preterm birth, and how mothers of ill and preterm infants define breastfeeding…
- Trial name
- NCT00527956
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Obesity, Labor Induction
Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial
Obese pregnant women (BMI ≥ 30 kg/m2) are more likely than their normal-weight counterparts to require induction of labor because of increased rates of obstetric complications including pregnancy related hypertensive disorders…
- Conditions
- Obesity, Labor Induction, Cesarean Delivery
- Trial name
- CROWN (NCT02639429)
- Testing
- Vaginal Misoprostol, Foley Balloon + Vaginal Misoprostol
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Very Preterm Infants
Plasma Protein Levels and Very Preterm Birth
The primary aim of this study is to investigate the relationship between early plasma protein levels and hemodynamics in very preterm infants during postnatal transition.
- Trial name
- ProHémie (NCT02007902)
- Testing
- Evaluation of the relationship plasma protein levels - neonatal hemodynamics
- Where
- 2 sites in France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Stillbirth, Infant, Low Birth Weight
UniSA BackOff! Study: Adelaide PrenaBelt Trial
Stillbirth (SB) is a devastating complication of pregnancy and contributes to over 2 million deaths globally every year. Over 20 million infants are born every year with low birth weight (LBW), which is associated with a twenty…
- Conditions
- Stillbirth, Infant, Low Birth Weight, Infant, Very Low Birth Weight, Sleep-Disordered Breathing
- Trial name
- NCT04437407
- Testing
- PB2-1 prototype, PB2-2 prototype, PB2-3 prototype
- Where
- Australia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Pregnancy, Stillbirth
Zambian Preterm Birth Prevention Study
This prospective non-intervention cohort study will enroll women in the first or early second trimester of pregnancy and follow them through delivery (or end of pregnancy) and 1 year postpartum.
- Conditions
- Pregnancy, Stillbirth, Preterm Birth
- Trial name
- ZAPPS (NCT02738892)
- Where
- 2 sites in Zambia
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections
Love Infection: A Dramatized Story Intervention (Telenovela/Soap Opera) for HIV Prevention
Purpose: To test the feasibility, acceptability of the IA intervention (four telenovela episodes), assessment of the mechanisms of action (self-efficacy, narrative engagement, and emotional elicitation) and conduct a randomized…
- Trial name
- IA (NCT05358366)
- Testing
- Infeccion de Amor (Love Infection)
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Contraception
Prospective Multi-Center Trial for FemBloc Permanent Birth Control
Prospective, multi-center, international, unblinded, single-arm trial of subjects undergoing FemBloc followed by ultrasound confirmation test.
- Trial name
- FINALE (NCT05977751)
- Testing
- FemBloc
- Where
- 12 sites in United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
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