Clinical trials: Parturition
Premature Birth
Interdisciplinary Hospital-home Intervention on Motor Development in Premature Children
Motor development of the premature infant often exhibits deviations that trigger functional limitations and disability. In Colombia, one out of every five births corresponds to premature babies.
- Trial name
- NCT04563364
- Testing
- Interdisciplinary hospital-home intervention, Convencional treatment
- Where
- Colombia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad de la Sabana
Hiv
Testing Two Models of PrEP Delivery in OBGYN Clinics
The HIV Center for Clinical and Behavioral Studies, the Albert Einstein College of Medicine and the Alliance for Positive Change will test two healthcare models that integrate PrEP into OBGYN services.
- Trial name
- NCT05015855
- Testing
- NP-PC PrEP, OBGYN-PrEP
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Obstetric Labor, Premature
Inflammation and Cell Maturation in Preterm Delivery Placentas - in Vitro and in Vivo Effect of Progesterone
The aim of this study is to investigate the In Vitro and In Vivo effect of progesterone on immature myeloid cells (IMC), inflammation characteristics and maturation into dendritic cells (DC).
- Trial name
- NCT03211338
- Testing
- Culture with progesterone, Culture without progesterone, Culture with growth factors
- Where
- Israel
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Nicotine Labeling for E-cigarettes
Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes
Current labels for the nicotine in e-cigarette/vaping products do not sufficiently convey information to the public. The aims of this study include developing and validating two new types of labels for the nicotine in vaping…
- Trial name
- NCT07553585
- Testing
- Updated Labeling
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Yale University
Bronchopulmonary Dysplasia (BPD), Chronic Lung Disease of Newborn
Long-Term Burden of BPD and Health-Related Quality of Life (BronQ Family)
The objective of this study is to examine the long-term impact of having a child with Bronchopulmonary Dysplasia (BPD) on the parents and caregivers from the time of diagnosis through adulthood.
- Conditions
- Bronchopulmonary Dysplasia (BPD), Chronic Lung Disease of Newborn, HRQOL (Health Related Quality Of Life)
- Trial name
- BronQ Family (NCT07134387)
- Testing
- N/A, no intervention, participation in survey
- Where
- Germany
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Global Foundation for the Care of Newborn Infants
Smoking, Smoking Cessation
Alternate Nicotine Delivery Systems and Airway Epithelial Biology
Cigarette smoking evokes major changes in the biology of the airway epithelium, the cell population that takes the brunt of the stress of cigarette smoke and the cell population central to the pathogenesis of chronic obstructive…
- Trial name
- NCT01974063
- Where
- 2 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Wheelchair Users
Effects of the WHO 8-step Wheelchair Service Delivery Process on Wheelchair Users in El Salvador: a Cohort Study
The objective of this study was to test the hypotheses that wheelchair-related health, wheelchair skills, wheelchair use, poverty probability, and quality of life would improve; and that the number of wheelchair repairs required…
- Trial name
- WUV (NCT04936087)
- Testing
- The World Health Organization 8 steps for manual wheelchair service delivery
- Where
- 13 sites in El Salvador
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Momentum Wheels for Humanity
Preterm Labor, Preterm Delivery
Two Methods of Diagnosing Preterm Labor
Use of modern diagnostic tools e.g. fetal fibronectin and ultrasound measurement of cervical length to diagnose preterm labor can result in improved outcomes compared to traditional diagnosis based on digital examination to…
- Trial name
- NCT01431885
- Testing
- Diagnosis by cervical length and fibronectin, Cervical change
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Low-Birth-Weight Infant
Implementation Research of Kangaroo Mother Care in Rural Pakistan.
Pakistan has a high neonatal mortality rate (55/1000 live birth)(1) and each year more than 200,000 newborns die. In rural Pakistan, more than 50% deliveries occur at home and majority by unskilled birth attendants(2).
- Trial name
- KMC (NCT03545204)
- Testing
- Kangaroo Mother Care Package, Routine Standard Care
- Where
- 2 sites in Pakistan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Childhood Infections
The Investigation of Methods to Capture Acute Respiratory and Gastrointestinal Infections of Children Aged 1 to 3 Years
This study serves as a feasibility study for a birth cohort study to investigate the influence of the sequence and load of infections and vaccinations on the development of the immune system of children.
- Trial name
- NCT02081833
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Helmholtz Centre for Infection Research
Prematurity
Different Intervention Models of Premature Infants Based on the ICF Biopsychosocial Model
Prematurity is an important risk factor for delayed neuropsychomotor development. The main objective of this study is to analyze the impact of different intervention models on the neuropsychomotor development of premature babies…
- Trial name
- NCT05989438
- Testing
- Orientations for families, Professional stimulation more orientations for families.
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Preterm Birth
Impact of Dietary Sodium Supplementation on Growth & Intestinal Microbiome
The purpose of this project is to determine the direct impact of sodium supplementation in preterm infants and to see the overall improvement of their growth and health status.
- Trial name
- NCT05546814
- Testing
- Sodium algorithm
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Suicide, Adolescent Behavior
Adapting the Suicide Safety Planning Intervention for Delivery to Adolescents in Mozambican Primary Care Settings
Globally, suicide is ranked as the second leading cause of death for youth ages 10-24 years, and more than 75% of all deaths by suicide occur in low- and middle-income countries (LMIC).
- Trial name
- NCT05346133
- Testing
- Suicide Prevention Intervention for Adolescents
- Where
- 2 sites in Mozambique
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Columbia University
Newborn; Vitality, Premature Infants
Infant Crying, a Bioacoustic Prognostic Signal for Neurodevelopment
Crying is a vital communication signal for the baby. Product of a complex physiological process, it reflects not only the organization and functioning of the cortical central nervous system and the function of sympathetic and…
- Conditions
- Newborn; Vitality, Premature Infants, Infant Development
- Trial name
- BABYCRY_1000 (NCT06332521)
- Testing
- Acoustic signal analysis method
- Where
- France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pregnancy
Behavioral and Environmetal Factors and Time to Delivery
This study, conducted at the Naval Medical Center in San Diego, CA, will determine if having vaginal intercourse in the last weeks of pregnancy decreases the risk of having a prolonged pregnancy.
- Trial name
- NCT00740506
- Testing
- Frequency of Intercourse
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV Prevention
Paper Applicator Acceptability Study
To assess the acceptability of a user-filled, paper, applicator for delivery of tenofovir (TFV) gel among women at high risk of acquiring human immunodeficiency virus (HIV) in rural KwaZulu-Natal, South Africa.
- Trial name
- NCT02179138
- Testing
- TFV 1% gel
- Where
- South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- CONRAD
Pain, Labor Pain
Effect of Using a Birth Ball on Birth Satisfaction and Pain in Pregnant Women During Labor
H0: There is no difference between birth satisfaction and pain levels of pregnant women who used and did not use a birth ball during labor.
- Conditions
- Pain, Labor Pain, Satisfaction
- Trial name
- NCT05312502
- Testing
- Birth Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Premature Birth, Birth Weight
Fresh RX: NHS 2020
This study is an evaluation of the Fresh Rx: Nourishing Healthy Starts program administered by Operation Food Search, a St. Louis-based nonprofit organization.
- Conditions
- Premature Birth, Birth Weight, Post Partum Depression, Health Care Utilization
- Trial name
- NCT04845230
- Testing
- FreshRx Nourishing Healthy Starts
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Influenza (Pandemic)
Safety Study of an Influenza Vaccine Against a Potential Pandemic Strain of Flu
The purpose of this study is to evaluate how well the vaccine is tolerated at sites where administrations are given, any effects it may have on subjects' wellbeing and whether it can produce antibody responses in the body that…
- Trial name
- NCT00347529
- Testing
- pPML7789 with and without pPJV2012 administered by PMED
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- PowderMed
HIV/AIDS
The Deliver Health Study
The investigators hypothesize that routing algorithm based ART delivery will be acceptable, efficient and improve health outcomes, specifically through meeting client needs, retaining HIV-positive persons in care, and achieving…
- Trial name
- NCT04027153
- Testing
- Fee based delivery
- Where
- South Africa
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Washington
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