Clinical trials: Paternal Age
We Will Retrospectively Assess Our Databases in Our Clinic, Instituto Valenciano de Infertilidad in Valencia (Spain)
Influence of Paternal Age on Assisted Reproduction Outcome
In the recent years, there is an increasing tendency to the parenthood delay in developed countries, and there is not enough information available regarding the influence of the male's age on fertility.
- Conditions
- We Will Retrospectively Assess Our Databases in Our Clinic, Instituto Valenciano de Infertilidad in Valencia (Spain), Searching for Assisted Reproduction Procedures, IUI Standard IVF/ICSI Cycles and Ovum Donation IVF/ICSI Cycles
- Trial name
- MALE AGING (NCT00510861)
- Where
- Spain
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility, Male
The Paternal Clock: Uncovering the Consequences of Advanced Paternal Age on Sperm DNA Fragmentation
Sperm DNA fragmentation (SDF) serves as a marker for chromatin and DNA damage in sperm. Assessing sperm DNA integrity is crucial in male fertility evaluation since high levels of SDF are associated with a greater number of…
- Trial name
- Paternal Clock (NCT05894356)
- Testing
- Study chart review
- Where
- Canada
- Volunteers
- 4,250 people
- Sponsor
- Clinique Ovo
Male Infertility, Advanced Paternal Age
Effectiveness of Live Motile Sperm Sorting Device on IVF Outcomes in Advanced Paternal Age
Male infertility contributes significantly to infertility, particularly in advanced paternal age men where sperm DNA fragmentation is increased.
- Conditions
- Male Infertility, Advanced Paternal Age, Assisted Reproductive Technology
- Trial name
- IVF (NCT07605182)
- Testing
- LensHooke® CA0 sperm sorting device, Density Gradient Centrifugation
- Where
- Vietnam
- Volunteers
- 378 people
- Sponsor
- Vietnam Military Medical University
Trisomy 21
Paternal Age and Fetal Aneuploidy
Trisomy 21, commonly known as down syndrome, is the most common chromosomal abnormality in humans. Advanced maternal age (AMA) is a well-recognized risk factor for trisomy 21, with the risk increasing significantly beyond the age…
- Trial name
- NCT05981521
- Testing
- Optimo prenatal screening test
- Where
- Canada
- Volunteers
- 7,141 people
- Sponsor
- Clinique Ovo
Fertility Issues, Single-Gene Defects
Whole Genome Sequencing (WGS) on IVF Embryos and Individual Patients
This research project aims to utilise recent advances in whole genome sequencing of preimplantation genetic diagnosis embryos to investigate the impact of paternal age on de novo mutation rates in IVF embryos.
- Trial name
- EmbryoWGS (NCT05739890)
- Testing
- Embryo genome sequencing, Parents genome sequencing
- Where
- 4 sites in United States, Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- GenEmbryomics Pty. Ltd
Infertility (IVF Patients), Oocyte Competence
The EPIC Study: Exploring Paternal Age and the Influence on Blastocyst Culture
This study aims to assess the effect of age of the male partner and the reproductive ability of sperm prepared via sperm selection devices (Zymot) compared to routine embryologist selected sperm after density gradient…
- Conditions
- Infertility (IVF Patients), Oocyte Competence, Sperm DNA Fragmentation, Paternal Age
- Trial name
- EPIC (NCT06629766)
- Testing
- Microfluidic sperm separation device, Density grade centrifugation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Reproductive Medicine Associates of New Jersey