Clinical trials: Pathological Conditions, Anatomical
Muscle Loss
Muscle Mass and Body Composition
ICUacquired weakness is a common complication of critical illness, particularly in patients receiving mechanical ventilation and/or suffering from conditions leading to the systemic inflammatory response syndrome.
- Trial name
- NCT03184623
- Testing
- muscle mass measurement
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- Frisius Medisch Centrum
Pancreatic Cystic Lesion
Antibiotic Prophylaxis for Endoscopic Ultrasound Guided Fine Needle Aspiration of Pancreatic Cystic Lesions
The purpose of this study is to determine whether the use of antibiotic prophylaxis is appropriate when performing a pancreatic cyst fine needle aspiration guided by endoscopic ultrasonography.
- Trial name
- NCT02261896
- Testing
- Ciprofloxacin
- Where
- Spain
- Volunteers
- 226 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Infraclavicular Brachial Plexus Block
2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula
Will the technique of adding lidocaine to bupivacaine fasten the onset of bupivacaine alone for infraclavicular brachial plexus block in end-stage renal disease (ESRD) patient?
- Trial name
- NCT00993746
- Testing
- Bupivacaine plus lidocaine, Bupivacaine 30 ml
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
Pain Alleviation, Dilatation and Evacuation
Use of Nitrous Oxide for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Dilatation and Evacuation
A randomised control study aiming to examine whether inhaled N2O/O2 during cervical preparation for second trimester dilatation and evacuation with osmotic dilators (laminaria) alleviates pain and is superior to placebo.
- Conditions
- Pain Alleviation, Dilatation and Evacuation, Laminaria Placement, Nitrous Oxide
- Trial name
- NCT05579288
- Testing
- Nitrous oxide (N2O/O2), Oxygen (O2)
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Hiatus Hernia
Hiatus Hernia in Old
hiatus hernia in frail patient is common and requires suregry
- Trial name
- NCT06935617
- Testing
- nissein
- Volunteers
- 266 people
- Sponsor
- Zagazig University
Congenital Diaphragmatic Hernia
Microbiome and Volatile Organic Compounds in Patients With CDH
Despite improved prenatal diagnostics and therapeutic possibilities, congenital diaphragmatic hernia (CDH) represents a cross-disciplinary challenge.
- Trial name
- CDHVOCS (NCT03787160)
- Testing
- initial VOC, initial fecal microbiome, initial pulmonary microbiome
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Pelvic Organ Prolapse, Urinary Incontinence
Intelligent Diagnosis and Treatment System for Pelvic Floor Dysfunction in Elderly Women
The aim of this study is to propose an intelligent diagnosis and treatment system for for pelvic floor dysfunction in elderly women.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Diagnosis
- Trial name
- NCT06372340
- Testing
- Personalized pelvic floor rehabilitation program generated by the intelligent diagnosis and treatment system., Standard pelvic floor muscle training(PFMT) program
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Zenker Diverticulum
Endoscopic Treatment of Zenker's Diverticulum (ZENKTUN)
Prospective comparative observational study in numerous reference centers in France, comparing Tunnelization (Z-POEM) versus Non-Tunnelization Techniques according to the usual practices.
- Trial name
- NCT06594718
- Testing
- Endoscopic diverticulotomy with Z-POEM, Endoscopic diverticulotomy using a non-tunnelization technique
- Volunteers
- 128 people
- Sponsor
- Société Française d'Endoscopie Digestive
Gingivitis, Plaque
Clinical Study of Toothpaste Containing Zinc Lactate as Compared to Colgate Cavity Protection Toothpaste.
The objective of this six-month clinical research study is to evaluate the clinical efficacy of two dentifrices - Toothpaste containing zinc lactate and Colgate Cavity Protection Toothpaste in reducing gingivitis and dental…
- Trial name
- NCT06563518
- Testing
- Meridol, Colgate Cavity Protection
- Where
- Thailand
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Lower Ureteric Stones
Efficacy of Antihistamine Drugs as Medical Expulsive Therapy Alone or in Combination With Alpha Blockers: A Prospective Randomized Controlled Study
we investigate the Efficacy of Antihistamine Drugs as Medical Expulsive Therapy Alone or in Combination with Alpha Blockers in distal ureter stone
- Trial name
- NCT06754410
- Testing
- Tamsulosin, Cetirizine, Cetirizine + Tamsulosin
- Where
- Egypt
- Volunteers
- 480 people
- Sponsor
- South Valley University
Catheter Blockage, Oncology
A Novel Ureteric Stent in Kidney Stone Patients and Oncology Patients Compared to a Conventional JJ Stent
Urological stents and catheters often lead to inflammation, causing pain and infection in the urinary tract. Moreover, 80% of stents are associated with pain, negatively impacting on QoL and mental health.
- Conditions
- Catheter Blockage, Oncology, Kidney Stone
- Trial name
- CASSETTE (NCT06815120)
- Testing
- Experimental ureteric stent with specially shaped side-holes that prevent stagnation points (i.e., areas of low flow that cause particles to settle and E&B), Qualitative interview
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Southampton
Perianal Fistula, Perianal Crohn Disease
Regenerative Therapy With Autologous Stromal Vascular Fraction Derived Mesenchymal Stem Cells and Platelet-rich Plasma to Treat Complex Perianal Diseases
Consecutive patients with complex anal fistula were prospectively followed for 12 months. Routine MRI was performed before and at 4 and 12 months after surgery. Continence was assessed likewise using a validated questionnaire.
- Conditions
- Perianal Fistula, Perianal Crohn Disease, Anal Fissure, Rectovaginal Fistula
- Trial name
- NCT05709717
- Testing
- Regenerative therapy with SVF-PRP to supplement perianal surgery
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Kantonsspital Winterthur KSW
Congenital Diaphragmatic Hernia
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)
Despite advances in prenatal diagnosis and postnatal therapies, including extracorporeal membrane oxygenation (ECMO), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity…
- Trial name
- FETO (NCT02710968)
- Testing
- 11540KE and Balt Goldbal 2 balloon
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Johns Hopkins University
Herniated Disc
Nucleoplasty for Contained Herniated Lumbar Discs
This is a prospective randomised double blind comparison trial. Fifty patients will be included, 25 in the nucleoplasty treatment group, 25 in the control group. The nucleoplasty group will undergo the nucleoplasty treatment.
- Trial name
- NCT00124774
- Testing
- Nucleoplasty
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Rijnstate Hospital
Vaginal Prolapse
Comparison of Two Vaginal Mesh Kits in the Management of Vaginal Prolapse
Our study is a non-randomized prospective study compared two groups matched for anterior/apical POP-Q grade: 84 received Elevate Ant™ single-incision mesh (group A) and 42 Perigee™ transvaginal mesh (group B).
- Trial name
- ELEPE (NCT03187574)
- Testing
- Elevate Ant™, Perigee™
- Volunteers
- 126 people
- Sponsor
- Hospices Civils de Lyon
Lumbar Disc Herniation With Radiculopathy
Comparison of the Effectiveness of Ultrasound-Guided Periradicular Injections in Patients With Lumbar Radicular Pain
This study aims to compare the effects of different ultrasound-guided periradicular injection solutions in patients with chronic unilateral radicular pain caused by a single-level lumbar disc herniation.
- Trial name
- NCT07771374
- Testing
- Lidocaine Hydrochloride 2% Injection Solution, Dexamethasone 4 Mg/mL Injectable Solution, Dextrose 5% Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Gastric (Stomach) Cancer, Frailty
Skeletal Muscle Mass Used to Assess Frailty in Older Gastric Cancer Patients
The primary aim of this study was to quantify the diagnosis of pre-surgical skeletal muscle mass in elderly gastric cancer patients and to analyse its correlation with frailty.
- Conditions
- Gastric (Stomach) Cancer, Frailty, Sarcopenia, Malnutrition Elderly
- Trial name
- NCT06763068
- Testing
- Skeletal muscle mass and frailty
- Where
- China
- Volunteers
- 575 people
- Sponsor
- Nanjing Medical University
Urinary Calculi
Use of a Ureteral Access Sheath During Ureteroscopy and Its Effect on Stone Free Rate
Patients with upper ureteral or renal stones will be randomized to undergoing ureteroscopy with or without a ureteral access sheath.
- Trial name
- NCT00199524
- Testing
- Navigator Ureteral Access Sheath
- Where
- 5 sites in Canada
- Volunteers
- 44 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Breast Cancer, Chemotherapy Effect
Effects of Creatine Supplementation in Breast Cancer Survivors
The purpose of this study is to test the hypothesis that creatine will accelerate adaptations associated with exercise in breast cancer survivors recently completing chemotherapy.
- Conditions
- Breast Cancer, Chemotherapy Effect, Muscle Weakness, Muscle Loss
- Trial name
- NCT04207359
- Testing
- Creatine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Skin Aging, Hair and Scalp Health
CyanthOx™ Capsule Efficacy Study
The goal of this clinical trial is to learn whether daily intake of CyanthOx™80 capsules can improve skin, scalp, hair, and selected blood biomarkers in healthy adults after 12 weeks.
- Conditions
- Skin Aging, Hair and Scalp Health, Hair Loss
- Trial name
- NCT07774117
- Testing
- CyanthOx™80 Group
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy ＆ Science
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