Clinical trials: Pathological Conditions, Anatomical
Pancreatic Fistula
Ultrasound Elastography for Prediction of Postoperative Pancreatic Fistula
The purpose of this study is to assess the value of preoperative objective modalities such as endoscopic ultrasound elastography and magnet resonance imaging in predicting development of postoperative pancreatic fistula in…
- Trial name
- PMPPOPF (NCT02589379)
- Testing
- Pancreatic Resection
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- University of Zurich
Alopecia, Alopecia, Androgenetic
Safety and Pharmacokinetics Study of New Formulation of Bimatoprost in Patients With Alopecia
This study will investigate the safety, tolerability, and pharmacokinetics of new formulation of bimatoprost following topical application in patients with alopecia.
- Conditions
- Alopecia, Alopecia, Androgenetic, Baldness
- Trial name
- NCT01189279
- Testing
- bimatoprost Formulation A, bimatoprost Formulation B, bimatoprost Formulation C
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Allergan
Hypothermia
Study of Heat and Intravenous Fluids for Exogenous Rewarming
The purpose of this study is to compare two novel active rewarming techniques in mildly hypothermic people. Volunteers will undergo 3 cooling trials in a circulating bath at 14 degrees celsius and will then be rewarmed with…
- Trial name
- SHIVER (NCT02339103)
- Testing
- Warmed IV fluids, Warmed perfusion pads
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stanford University
Stricture, Esophageal Stricture
Collagenase Clostridium Histolyticum for Refractory Iatrogenic Esophageal Strictures
In this open-label pilot study we want to investigate whether intralaesional injection with collagenase clostridium histolyticum (XiapexR) into the esophageal stricture followed by dilation 24 hours later improves the outcome of…
- Conditions
- Stricture, Esophageal Stricture, Anastomotic, Collagenosis
- Trial name
- NCT03898661
- Testing
- Collagenase histiolyticum
- Where
- Belgium
- Volunteers
- 2 people
- Sponsor
- University Hospital, Ghent
Lumbar Disc Herniation
Impact of Transforaminal Epidural Steroid Injection in Lumbar Disc Prolpse on Micro RNA-155 Serum Level
Chronic pain could be considered a brain disease as it can affect multiple aspects of brain function, chemistry, neural networks and structure. Pain is associated with impaired cognitive function (1).
- Trial name
- NCT05626283
- Testing
- transforaminal epidural injection., micro RNA-155 serum level
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Renal Stone Disease
Direct In-Scope Suction Versus Standard Flexible Ureterorenoscopy
This prospective study aims to compare the clinical, perioperative, and postoperative outcomes of flexible ureterorenoscopy using a direct in-scope suction system (DISS) with standard flexible ureterorenoscopy in patients…
- Trial name
- NCT07864194
- Testing
- Standard flexible ureterorenoscope, Flexible ureterorenoscope with direct in-scope suction
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hitit University
Colonic Polyps
High Definition Endoscopy With i-Scan for Small Colonic Polyp Evaluation: The HiScope Study
Current standard practice is to remove all colonic polyps found during colonoscopy as it has not been possible to distinguish between polyps with some malignant potential (adenomatous) and those with negligable malignant…
- Trial name
- HiSCOPE (NCT01761279)
- Testing
- High definition white light endoscopy
- Volunteers
- 84 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Parastomal Hernia
HyPER - Hybrid Parastomal Endoscopic Repair
Retrospective single-center study analyzing long-term outcomes of Hybrid Parastomal Endoscopic Repair (HyPER) in 200 patients with symptomatic parastomal hernias, including recurrence, complications, and quality of life.
- Trial name
- HyPER (NCT07064694)
- Testing
- Hybrid Parastomal Endoscopic Repair (HyPER)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Swissmed Hospital
Sarcopenia, Sarcopenic Obesity
Effects of Sarcopenia on General Health Status in Elderly: a Population-based Study
This is a observational study, that aimed to determine the prevalence of sarcopenia using European Wording Group on Sarcopenia in Older People (EWGSOP) algorithm in a general elderly population in Algarve region (Portugal).
- Conditions
- Sarcopenia, Sarcopenic Obesity, Frailty
- Trial name
- NCT05918159
- Testing
- Sarcopenia Assessment
- Where
- Portugal
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Universidade do Algarve
Obesity, Compensated Cirrhosis
OPTIMIzing muScle Preservation in paTients wIth Cirrhosis
Patients with obesity and cirrhosis benefit from weight loss but are prone to sarcopenia (loss of muscle mass, strength, and function).
- Conditions
- Obesity, Compensated Cirrhosis, Sarcopenia
- Trial name
- OPTIMISTIC (NCT05367596)
- Testing
- Continuous Energy Restriction (CER), Alternate Day Modified Fasting (ADMF), Group Health Education Sessions
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Kidney Stone
Effects of Abdominal Cushion on PCNL in Prone Position
Percutaneous nephrolithotomy (PCNL) is the first choice for the treatment of ≥ 2cm renal stones. The positions of PCNL includes supine, prone and lateral. PCNL has been performed in my center for nearly twenty years.
- Trial name
- NCT03797027
- Testing
- Percutaneous Nephrolithotomy without an abdominal cushion, Percutaneous Nephrolithotomy with an 5 cm abdominal cushion
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Rectal Fistula
Mesenchymal Stem Cells (MSCs) for Perianal Fistula
OSSM-001 will be evaluated in a double blind, randomized phase I safety study of a single injection of 100 and 300 million bone marrow derived MSCs in 16 patients with refractory perianal fistulas in the setting of Crohn's…
- Trial name
- NCT05407766
- Testing
- OSSM-001
- Sponsor
- Ossium Health, Inc.
Pelvic Organ Prolapse
Guided IMagery and Patient Satisfaction (GIMPS) Following Urogynecological Surgery
We hypothesize that women who use GIM pre-operatively will feel more prepared for surgery, have less anxiety on the day of surgery and have higher satisfaction scores 6 weeks after surgery compared to women who undergo our…
- Trial name
- GIMPS (NCT02165280)
- Testing
- Guided IMagery (GIM)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Loyola University
Arteriovenous Fistula
Dexmedetomidine and Propofol As Sole Sedative Agent for Patients Undergoing Arteriovenous Fistula Surgery
The investigators designed a prospective randomized study to compare the conventionally used sedative drug propofol with a latest alternative dexmedetomidine (DEX), in patients with end-stage renal disease undergoing…
- Trial name
- NCT02447796
- Testing
- Propofol, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Hair Loss/Baldness
Role of Bandage After FUE Hair Transplantation
The aim of this interventional study is to determine the role of bandage on the follicular donor sites on the scalp after FUE hair transplantation.
- Trial name
- NCT05984862
- Testing
- Bandage
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pak Medical and Diagnostic Center
Hernia, Ventral, Hernias Intestinal
Optimization of Surgical Treatment of Patients With Incisional Ventral Hernias
The goal of our work of optimization of the treatment of postoperative hernias is to improve the results of treatment of patients with median and median-lateral postoperative hernias of medium (W2) and large (W3) sizes by…
- Conditions
- Hernia, Ventral, Hernias Intestinal, Hernia Abdominal Wall
- Trial name
- NCT05734222
- Testing
- A new method of repair of the abdominal wall of mid-lateral postoperative ventral hernias
- Where
- Russia
- Volunteers
- 110 people
- Sponsor
- Samara State Medical University
Urolithiasis
Study of Tomography of Nephrolithiasis Evaluation
This is a multi-center, randomized controlled trial of ultrasonography (ultrasound) compared to computed tomography (CT) for the initial emergency room evaluation of patients with suspected renal colic.
- Trial name
- STONE (NCT01451931)
- Testing
- Point-of-care Ultrasound, Radiology Ultrasound, Radiology CT
- Where
- 15 sites in United States
- Volunteers
- 2,776 people
- Sponsor
- University of California, San Francisco
Stroke, Plaque, Atherosclerotic
ParisK: Correlation of Imaging Techniques With Histology
The possibility to identify the risk of rupture of a carotid plaque will have tremendous impact in clinical decision making. A vulnerable plaque is considered to have a large lipid rich necrotic core (LRNC), a thin fibrous cap…
- Trial name
- ParisK (NCT01709045)
- Testing
- Magnetic Resonance Imaging (MRI), Dual-Energy Computed Tomography (DECT), Ultrasound
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Chest Pain, Stenosis
Diagnosis of Myocardial Ischemia With MCG Using SPECT as a Reference Standard
This is a prospective clinical study aiming to investigate the efficacy of Magnetocardiography (MCG) in detecting myocardial ischemia in patients of a suspected non-ST-elevation-acute coronary syndrome (NSTE-ACS) by using Single…
- Conditions
- Chest Pain, Stenosis, Myocardial Ischemia
- Trial name
- NCT06255769
- Testing
- Magnetocardiography, Single photon emission computed tomography (SPECT)
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Qilu Hospital of Shandong University
Common Bile Duct Stone
Treatment of Common Bile Duct Stones
ABSTRACT Introduction: Common bile duct (CBD) stone is a common clinical situation, especially in Asia area. Laparotomy and laparoscopic surgical procedure are often used for treatment.
- Trial name
- NCT03442205
- Testing
- LC + LCBDE + ENBD + primary closure of CBD, ERCP technique + LC, LC + LCBDE + primary closure of CBD
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
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