Clinical trials: Pathological Fractures
Elbow Fracture
The Post-Operative Pain Management of Pediatric Supracondylar Elbow Fractures
The goal of this study is to compare different ways of treating pain after surgery. This research study involves subjects who have a supracondylar elbow fracture and need surgery.
- Trial name
- NCT01328782
- Testing
- Oxycodone with Acetaminophen, Bupivacaine 0.25%, Ropivacaine 0.20%
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Colorado, Denver
Delirium
Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period
Delirium (acute confusion) is a highly prevalent condition among hospitalized elders with substantial morbidity within the hospital and beyond.
- Trial name
- SHARP (NCT00586196)
- Testing
- donepezil
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Beth Israel Deaconess Medical Center
Serratus Anterior Plane Block, Thoracic Paravertebral Block
Ultrasound- Guided Continuous Serratus Anterior Plane Block Versus Ultrasound- Guided Continuous Thoracic Paravertebral Block in Multiple Traumatic Rib Fractures.
The aim of this study is to compare the analgesic efficacy of ultrasound guided continuous SAP block and ultrasound guided continuous TPVB in patients with multiple traumatic rib fractures.
- Conditions
- Serratus Anterior Plane Block, Thoracic Paravertebral Block, Ultrasound, Multiple Traumatic Rib Fractures
- Trial name
- NCT04710823
- Testing
- Thoracic paravertebral block, Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Hip Fracture, Frailty
Starting a Testosterone and Exercise Program After Hip Injury
This study is a randomized controlled double-blinded multi-center clinical trial enrolling female hip fracture patients who are 65 and older.
- Conditions
- Hip Fracture, Frailty, Sarcopenia
- Trial name
- STEP-HI (NCT02938923)
- Testing
- Testosterone, Supervised exercise training, Home exercise program
- Where
- 8 sites in United States
- Volunteers
- 129 people
- Sponsor
- Washington University School of Medicine
Postoperative Pain
Morphine Added to Ropivacaine for FICB for Postoperative Analgesia
prospective, randomized double blinded study to investigate the effects of morphine as an adjuvant to ropivacaine on FICB
- Trial name
- NCT03875274
- Testing
- Ropivacaine, Morphine, Ropivacaine, Saline
- Where
- Nepal
- Volunteers
- 70 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Hip Fractures, Blood Loss
Safety and Efficacy of Oral TXA in Reducing Blood Loss and Transfusion in Hip Fractures
The primary objective of this study is to assess the safety and efficacy of Tranexamic acid (TXA) in reducing blood loss and transfusion requirements for patients with osteoporotic hip fractures.
- Trial name
- NCT02908516
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Osteoarthritis, Rheumatoid Arthritis
Project JAY THA Registration Study
This is a prospective, randomized, multicenter clinical study in Chinese subjects to compare the safety and efficacy of the Delta PLUS Femoral Head and SL-TWIN Stem with BIOLOX forte ball head and SL-PLUS Stem in total hip…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- NCT02347384
- Testing
- Delta PLUS Femoral Head + SL-TWIN Stem, BIOLOX forte ball head + SL-PLUS Stem
- Where
- 4 sites in China
- Volunteers
- 100 people
- Sponsor
- Smith & Nephew Orthopaedics (Beijing) Limited
Elbow Dislocation, Heterotopic Ossification
Tranexamic Acid Prophylaxis for Heterotopic Ossification in Elbow Fracture-Dislocation Surgery
Heterotopic ossification (HO) following elbow fracture-dislocation is a well-recognized condition that can lead to reduced range of motion, increased pain, and the necessity for repeat surgeries.
- Trial name
- NCT06088407
- Testing
- with Tranexamic acid
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Osteoporosis, Osteoporotic Fractures
Osteoporosis and Knee Insufficiency Fracture
Osteoporosis is a systemic bone disease characterized by low bone mass and microarchitectural deterioration of bone tissue with consequent bone fragility and susceptibility to fracture.
- Conditions
- Osteoporosis, Osteoporotic Fractures, Osteonecrosis
- Trial name
- NCT02332681
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- University of Sao Paulo General Hospital
Foot Fracture, Ankle Fractures
Use of Sterile HemaClear Tourniquet Below Calf Versus Pneumatic Tourniquet at the Thigh for Ankle and Foot Surgery
This is a Randomized controlled trial evaluating the effects of the use of Sterile HemaClear Tourniquet Below Calf Versus Pneumatic Tourniquet at the Thigh for Ankle and Foot Surgery The trial will randomize 60 patients into an…
- Conditions
- Foot Fracture, Ankle Fractures, Ankle Injuries, Foot Injuries and Disorders
- Trial name
- HemaClear (NCT04818775)
- Testing
- HemaClear, Pneumatic Tourniquet
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital do Coracao
Chronic Kidney Diseases, Hyperparathyroidism, Secondary
Analysis of Bone Microarchitecture With HR-pQCT of Patients With Chronic Kidney Disease (CKD) Candidates for Renal Transplantation
While the duration of renal transplant function has increased over the last decade kidney transplanted patients (KTP) still exhibit a fracture risk 4 times higher than in the general population.
- Trial name
- TRANSBONE (NCT02523209)
- Testing
- HR-pQCT, DEXA
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sarcopenia, Hip Fracture
Hyperprotein Nutritional Intervention in Elderly Patients With Hip Fracture and Sarcopenia
1. RATIONALE The unique characteristic of our study lies in the attempt to reverse the functional impairment experienced by sarcopenic patients with hip fracture using nutritional intervention.
- Trial name
- HIPERPROT (NCT01404195)
- Testing
- Ensure Plus Advance
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital Viamed Valvanera, Spain
Spondylolisthesis, Neurologic Deficits
A Postmarket Surveillance Study of the Paradigm Spine Dynamic Stabilization System (DSS)
The purpose of the Post-Market Surveillance study is to evaluate safety.
- Conditions
- Spondylolisthesis, Neurologic Deficits, Kyphosis, Pseudarthrosis
- Trial name
- DSS (NCT01461005)
- Testing
- Dynamic Stabilization System (DSS)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Paradigm Spine
Delirium
Hip Fracture Surgery in Elderly Patients
The objective of this study is to evaluate the incidence of Post-Operative Delirium (POD), diagnosed with the Confusion Assessment Method (CAM), in elderly patients undergoing hip fracture surgery under general anaesthesia with…
- Trial name
- HIPELD (NCT01199276)
- Testing
- Xenon, Sevoflurane
- Where
- 13 sites in Belgium, France and 4 more
- Volunteers
- 256 people
- Sponsor
- Air Liquide Santé International
Humerus Fracture, Rotator Cuff Injuries
Myofascial Release in Shoulder Pathologies
Shoulder pathology has a high prevalence in the field of musculoskeletal diagnoses, as well as being a common etiology in cases of disability. Passive and active-assisted kinesitherapy are used in the physiotherapy protocol.
- Trial name
- NCT04944446
- Testing
- Treatment
- Where
- Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Hip Fractures, Pain, Acute
PENG: an Estimation of ED50 in Neck of Femur Fracture
The effective dose of local anaesthetic used in PENG blocks to achieve analgesia in patients with fractured neck of femur is unknown.
- Trial name
- NCT05095025
- Testing
- Bupivacaine Hydrochloride 20ml injectate
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- University College Cork
Hip Fractures, Analgesia
Postop Pain Control in Hip Fracture Surgery: Fascia Iliaca Compartment Block Versus Fracture Block
The investigators propose to investigate the effect of intraoperative FICB and intrafragmentary fracture blockade on postoperative pain and opiate consumption using a randomized controlled trial study design.
- Conditions
- Hip Fractures, Analgesia, Opioid Use, Pain, Postoperative
- Trial name
- NCT04335461
- Testing
- Cephalomedullary nailing of extracapsular hip fracture, cephalomedullary nail, Regional Anesthetics
- Where
- United States
- Sponsor
- Montefiore Medical Center
Bacterial Infection
Study to Assess Safety and Clinical Activity of Local MBN-101 in Treatment of Infected Bone Sites
This study evaluates the safety and clinical benefit of MBN-101 administered intraoperatively to osteosynthesis or osteomyelitis sites for patients diagnosed with an orthopedic infection, with or without orthopaedic hardware.
- Trial name
- NCT02436876
- Testing
- MBN-101
- Where
- 6 sites in United States
- Volunteers
- 29 people
- Sponsor
- Microbion Corporation
Hip Fracture, Analgesia
Ultrasound Percapsular Nerve Group Block VS Fascia Iliaca Block for Hip Fracture
Spinal anesthesia (SA) is a widely accepted anesthetic technique for hip fracture repair among elderly. Positioning for SA can be extremely painful. Effective management of pain is important for these patients comfort.
- Conditions
- Hip Fracture, Analgesia, Acute Pain
- Trial name
- NCT04285333
- Testing
- fascia iliaca block, percapsular nerve group block
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University Tunis El Manar
Hip Fractures, Pain, Postoperative
The Effect of TENS on Pain and Analgesic Consumption
The surgical treatment of an individual with osteoarthritis and hip fracture is provided by hip replacement surgery. While restructuring the joint surfaces with surgery, it is aimed to provide both hip joint movements and to…
- Conditions
- Hip Fractures, Pain, Postoperative, Analgesia
- Trial name
- NCT05939804
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University