Clinical trials: Pathology
Metabolic Disease, Inflammation
Effects of Salmon Fishmeal Ex Vivo (FishMeal Ex Vivo)
Diabetes contributes significantly to the burden of disease in Norway and cardiovascular disease is the main cause of mortality. Both lean and fatty fish are shown to have beneficial health effects.
- Conditions
- Metabolic Disease, Inflammation, Endocrine; Obesity
- Trial name
- NCT04078958
- Testing
- Salmon fishmeal, Whey
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Hand Massage
The Effect of the Hand Massage A Women Undergoing Brachytherapy
Background Gynecologic cancers are among the ten most common cancers among women. During brachytherapy, women can have pain and situational anxiety due to the treatment.
- Trial name
- NCT05937607
- Testing
- Hand massage
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Hernia, Ventral, Neuromuscular Blockade
Prospective Randomized Trial of Moderate vs Deep Neuromuscular Blockade During Laparoscopic Ventral Hernia Repair
The proposed study aims to assess the effect of different levels of muscle relaxation on the success of low-pressure insufflation, surgical conditions and patient recovery following laparoscopic repair of a ventral hernia (VHR)…
- Conditions
- Hernia, Ventral, Neuromuscular Blockade, Pneumoperitoneum
- Trial name
- NCT03201744
- Testing
- Patients will be randomized to moderate (TOF 1-2) or deep (post tetanic count 1-2) relaxation. Low pressure insufflation (start pressure set at 8 mm Hg)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stony Brook University
COPD Exacerbation
Mast Cells and Its Proteases in COPD
Mast cells proteases such as chymase and tryptase will be studied in the tissue of small and large airways in COPD patients
- Trial name
- NCT06392334
- Testing
- Biopsy
- Where
- Russia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Voronezh N.N. Burdenko State Medical Academy
Overweight and Obesity, Health Behavior
Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II
College students are in a newly independent phase of life; many of whom encounter unhealthy dietary decision- making, barriers to physical activity, and poor sleep behaviors.
- Conditions
- Overweight and Obesity, Health Behavior, Sleep Deprivation
- Trial name
- NCT02996864
- Testing
- Healthy Detours App, Fat Secret App
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Tourette Syndrome, Habit Reversal Training
Extinction Learning in Adults With Tourette Syndrome
Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still…
- Conditions
- Tourette Syndrome, Habit Reversal Training, Tic Disorders, Tics
- Trial name
- NCT04498364
- Testing
- Habit Reversal Training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Postoperative Pain
Efficacy of Modified Thoracoabdominal Nerves Block Through Perichondrial Approach in Total Laparoscopic Hysterectomies
TAPA is a new analgesic block technique that involves the injection of local anesthetics into the thoracoabdominal nerves using a perichondrial approach.
- Trial name
- NCT06116409
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Anosognosia, Alzheimer's Disease
Functional Magnetic Resonance Imaging (fMRI) of Anosognosia in Amnestic Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)
This is a three year fMRI study conducted at the University of Wisconsin (UW) Hospital and the William. S. Middleton VA Hospital.
- Conditions
- Anosognosia, Alzheimer's Disease, Mild Cognitive Impairment
- Trial name
- NCT00908999
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy, Obesity
Effect of Ghrelin on Sympathetic Nervous System
Ghrelin is a newly discovered peptide that is secreted by the stomach. Its main role is to stimulate food intake but recent studies indicate that it also acts on the cardiovascular system to confer beneficial effects.
- Trial name
- NCT00912587
- Testing
- ghrelin
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Baker Heart and Diabetes Institute
Chronic Kidney Diseases, Hemodialysis Complication
Exposure Of Bisphenol Analogues In Chronic Kidney Disease and Dialysis Patients
In this retrospective study, the serum levels of Bisphenol A (BPA) and three BPA analogs, namely, bisphenol B (BPB), bisphenol S (BPS), and bisphenol F (BPF), in patients with CKD, patients on dialysis therapy and healthy control…
- Trial name
- NCT04100421
- Where
- China
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Obesity, Metabolic Syndrome
Impact of Metabolic Flexibility on Changes in Metabolic Health
Metabolic flexibility is the capacity to adapt fuel oxidation to fuel availability so that ATP synthesis can match its cellular demands.
- Trial name
- METPROS (NCT06340321)
- Testing
- Metabolic flexibility in the fasted state, Metabolic flexibility in euglycemic-hyperinsulinemic clamp, Metabolic flexibility in the metabolic chamber
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Back Pain
Muscle Activation Characteristics During Spinal Manipulation in Healthy and Low Back Pain Participants
To characterize muscle activity through electromyography (EMG) of the lumbar spine during high velocity, low amplitude (HVLA) spinal manipulation according to parameters of practitioner contact (location, applied force) in…
- Trial name
- NCT03483714
- Testing
- Spinal Manipulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Denver
Adult Women
Interoceptive Awareness and Dream Themes
Individual differences in reported dream themes may reflect not only waking emotional and cognitive experiences but also characteristic ways of attending to, interpreting, and regulating bodily signals.
- Trial name
- NCT07716514
- Where
- Turkey (Türkiye)
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Scarring
Dose Ranging Study to Evaluate the Safety and Tolerability of SCX-001 Cream in Healthy Volunteers With Induced Dermal Incisions
The purpose of this study is to assess the safety and local tolerability of two different concentrations of of SCX-001 cream, as compared to placebo, when topically applied twice a day for 21 days to artificially induced dermal…
- Trial name
- NCT03036306
- Testing
- SCX-001
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- ScarX Corp
Gonorrhea Female, Chlamydia Females
The Integrated Female Sexually Transmitted Infection Testing for HIV Epidemic Control Through PrEP (IN-STEP) Study
Globally, new HIV infections are concentrated in eastern and southern Africa where the infections are largely acquired by women outside of known key populations.
- Conditions
- Gonorrhea Female, Chlamydia Females, Syphilis Female, Trichomonas Vaginalis
- Trial name
- IN-STEP (NCT06743204)
- Testing
- Self-Reported Risk Screening for PrEP and Diagnostic STI testing, Self-reported risk screening for PrEP and syndromic management for STIs
- Where
- Uganda
- Volunteers
- 5,560 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity
CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users
This study aims to assess the impact of GLP-1 receptor agonists, semaglutide and tirzepatide, on food cravings and diet quality in individuals with overweight or obesity.
- Trial name
- NCT06467604
- Testing
- Surveys, Indirect Calorimetry, Body composition
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Cardiac Arrhythmia
Maestro Handheld Cardiac Monitor Validation
The purpose of this study is to demonstrate that the Maestro hand held heart monitor can accurately diagnose Atrial Fibrillation, atrial flutter or normal sinus rhythm in patients.
- Trial name
- NCT02977104
- Testing
- Maestro ECG
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity, Knee Osteoarthritis
BLOOM Forward: Investigating Weight Loss Impact on TJAC Patients
The goal of this clinical trial is to prospectively assess the efficacy of the BLOOM program, a comprehensive weight loss dietary and lifestyle program, in a population of patients living with obesity and awaiting hip or knee…
- Conditions
- Obesity, Knee Osteoarthritis, Hip Osteoarthritis, Arthroplasty Complications
- Trial name
- NCT06103552
- Testing
- Building Lifestyle Options for Orthopedic Mobility (BLOOM)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Invasive Group B Streptococcus Disease
Antibody Levels Associated With Reduced Risk of Invasive Group B Streptococcus Disease in Infants Aged Less Than 90 Days
Compare anticapsular antibody levels against Group B Streptococcus at delivery in mothers and their infants who develop disease versus those who do not.
- Trial name
- NCT02099149
- Where
- South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novartis
Clinical Infection, Microbial Colonization
Effect of Gut Microbiota and Fecal Inflammatory Marker on Childhood Gastroenteritis
Childhood gastroenteritis establishes gastrointestinal disease and increase the economic burden, and the pediatric population is especially vulnerable to these gastrointestinal infections.
- Conditions
- Clinical Infection, Microbial Colonization, Gastroenteritis, Inflammatory Response
- Trial name
- NCT03856138
- Where
- Taiwan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital