Clinical trials: Patient Cataract, open to volunteers
Cataract, Fuchs Endothelial Corneal Dystrophy
Partial Range Of Field IOLs in DMEK-Enabled Procedures
Study Overview This study aims to evaluate the visual outcomes, quality of vision, and patient satisfaction after receiving an extended range PRoF intraocular lens (IOL) during triple Descemet Membrane Endothelial Keratoplasty…
- Trial name
- PROFIDE (NCT07441616)
- Testing
- combined cataract and lamellar endothelial keratoplasty
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Presbyopia Correction, Presbyopia
Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match
The purpose of the study is to evaluate the binocular clinical endpoints of distance, intermediate, and near vision and patient reported outcomes utilizing mini-monovision versus mix-match approaches for the correction of…
- Conditions
- Presbyopia Correction, Presbyopia, Dysphotopsia, Visual Acuity
- Trial name
- NCT07860567
- Testing
- TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Dr. Daniel H. Chang, MD
Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery
Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts.
- Trial name
- NCT06781970
- Testing
- Oral Vitamin C
- Where
- 2 sites in Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Lens Diseases
Evaluating Presbyopia-Correcting IOLs in Complex Cataract Cases With Anterior Segment Abnormalities
The goal of cataract surgery has evolved from simply restoring sight to providing clear and comfortable full-range vision. Traditionally, monofocal IOLs remain the routine choice for special cases with anterior segment…
- Trial name
- NCT07321756
- Testing
- Unilateral Posterior Chamber Implantation of Presbyopia-Correcting IOL, Unilateral Posterior Chamber Implantation of Monofocal IOL
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataract
Comparing Monofocal IOLs in Highly Myopic Cataract Patients
Comparison of Postoperative Outcomes in Patients with High Myopia Undergoing Cataract Surgery Implanted with Extended Depth of Focus Intraocular Lens (ICB00) and Monofocal Intraocular Lens (ZCB00)
- Trial name
- NCT06905938
- Testing
- no intervention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
IOL, Cataract
Clinical Outcomes of Patients with LAL+ in At Least One Eye
The objective of this study is to collect data on bilateral pseudophakic patients implanted with the RxSight Light Adjustable Lens+ (LAL+) in at least one eye
- Trial name
- NCT06650358
- Testing
- Light Adjustable Lens+
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Frank A. Bucci, Jr., M.D.
Primary Open-Angle Glaucoma (POAG), Cataract
Aqueous Humor and Ocular Tissue Analysis in Glaucoma and Cataract
This observational study will compare proteomic and elemental profiles of aqueous humor and ocular tissues in patients with primary open-angle glaucoma (POAG) and cataract versus cataract controls without glaucoma.
- Trial name
- NCT07462000
- Testing
- Phacoemulsification With Intraocular Lens Implantation and Deep Sclerectomy, Phacoemulsification With Intraocular Lens Implantation
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Military Institute od Medicine National Research Institute
Cataract
Effect of Surgical Planning Prompts on Elective Surgery Acceptance Rate
This randomized, double-blind, controlled trial investigates whether prompting patients facing elective cataract surgery to articulate their specific conditions for choosing surgery (a structured self-reflection intervention…
- Trial name
- NCT07544641
- Testing
- Structured Surgical Planning Self-Reflection
- Volunteers
- 268 people
- Sponsor
- Tongji University
Cataract
Outcomes of Clareon PanOptix Pro in Patients With Prior Myopic Refractive Surgery
This study is a Single center, single arm, prospective, observational study of clinical outcomes following bilateral cataract surgery and Clareon PanOptix Pro implantation.
- Trial name
- NCT06555289
- Testing
- Clareon PanOptix Pro IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Juliette Eye Institute Research Center
High Myopia, Cataract
The Role of Capsular Tension Rings in Intraocular Lens Stability in High Myopia Cataract Patients: A Prospective Self-Controlled Study
Study Purpose: This prospective, self-controlled clinical study aims to evaluate the impact of capsular tension rings (CTR) on intraocular lens (IOL) stability in high myopia patients undergoing bilateral cataract surgery.
- Trial name
- NCT07052825
- Testing
- CTR implantation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jin Yang
Cataract, Hypertension
Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery
Cataract surgery in elderly patients with controlled hypertension carries a risk of hemodynamic instability, particularly fluctuations in mean arterial blood pressure (MAP).
- Trial name
- NCT07080229
- Testing
- Intranasal dexmedetomidine, Intranasal normal saline
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Suez Canal University
Pseudoexfoliation Syndrome, Cataract
Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation Syndrome
This prospective study aims to evaluate the influence of corneal biomechanical properties on surgically induced astigmatism following standard phacoemulsification cataract surgery in patients with pseudoexfoliation syndrome…
- Conditions
- Pseudoexfoliation Syndrome, Cataract, Astigmatism
- Trial name
- NCT07722247
- Testing
- phacoemulsification cataract surgery
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- Kata Culina
Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer
The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients
The study was designed as a prospective, observational study. Pediatric patients under 18 years of age scheduled for peripheral vascular access placement during day-case surgery or non-operating room anesthesia (NORA) will be…
- Conditions
- Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer, Cataract, Crohn's Disease
- Trial name
- NCT07315711
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sibel Seçkin Pehlivan
Deprivation Amblyopia, Congenital Cataract
Augmented Reality Training for Amblyopia After Congenital Cataract Surgery
This study will evaluate whether augmented reality training is effective and safe for treating unilateral amblyopia after congenital cataract surgery in children.
- Trial name
- NCT07693790
- Testing
- Augmented Reality Amblyopia Training, Conventional Patching
- Volunteers
- 88 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
Clinical Outcomes of Sedation in Cataract Surgery Performed Under Topical Anesthesia
This study aims to evaluate the clinical outcomes of different sedation strategies in patients undergoing cataract surgery performed under topical anesthesia.
- Trial name
- SADCAT (NCT07347886)
- Testing
- Normal Saline, Midalozam, Fentanyl (IV)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University - Cerrahpasa
Cataract and IOL Surgery, Cataract Surgery Anesthesia
The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage
The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon.
- Conditions
- Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
- Trial name
- NCT07223866
- Testing
- High IOP Setting, Low IOP Setting
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Matthew Rauen
Ophthalmology, Cataract Surgery Anesthesia
An Extension Test of Whether to Use Oral Anti-anxiety Drugs (Alprazolam) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction
Phacoemulsification is one of the most used surgical methods for cataract surgery today, and the surgeries are under the anesthetic and sedative to make it comfortable and safe for patients.
- Conditions
- Ophthalmology, Cataract Surgery Anesthesia, Oral Anxiolytic, Satisfaction Survey
- Trial name
- NCT06874452
- Testing
- Alprazolam (Xanax)
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Hospital
Cataract, Intraocular Lens
Phacoemulsification and Intraocular Lens Implantation: Patient Registry
The aim of the study is to create a patient registry that will allow for comparison of cataract treatment outcomes using phacoemulsification with implantation of different types of intraocular lenses.
- Trial name
- NCT07276217
- Testing
- Intraocular lens
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Sensor Cliniq
Recruitment of Participants
Study of the Correlation Between Preoperative Precise Biometrics, Spatial Assessment and Postoperative Visual Quality in Cataract Patients
This study summarizes the experience of precision treatment and postoperative management of various types of cataract, and intend to further improve the quality of Clinical Cataract diagnosis and treatment.
- Trial name
- NCT04833491
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health