Clinical trials: Patient Noncompliance
Colorectal Cancer
Adherence to Minimally Invasive Testing
Colorectal cancer (CRC) screening has been demonstrated to reduce long term disease burden and costs. Unfortunately, less than 65 % of age-eligible persons in the US are actually screened for CRC.
- Trial name
- ADMIT (NCT02251782)
- Testing
- Epi proColon Test, Fecal Immunochemical Test (FIT)
- Where
- 2 sites in United States
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Epigenomics, Inc
Anxiety Postoperative, Patient Non-Compliance
Psychological and Physical Distress and Care Needs in Operable Lung Cancer Patients Receiving Surgery
The lung cancer is the most has the life minacity in all kinds of cancers, and it also remains the most common cause of cancer-related death in the world.
- Conditions
- Anxiety Postoperative, Patient Non-Compliance, Psychological Distress
- Trial name
- NCT01362842
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Schizophrenia, Schizo Affective Disorder
Financial Incentives to Improve Acceptance of Antipsychotic Injections
There is a lack of incentive approach for patients who suffer from schizophrenia yet lack the insight to accept treatment. Most existing approaches involve coercion and involuntary hospitalizations.
- Conditions
- Schizophrenia, Schizo Affective Disorder, Bipolar I Disorder
- Trial name
- NCT03192631
- Testing
- Financial incentive
- Volunteers
- 20 people
- Sponsor
- Focus Community Mental Health Team
Compliant Behavior, Self-Control
Episodic Future Thinking and Compassion
During the COVID-19 (Coronavirus Disease 2019) pandemic, public health departments have issued guidelines to limit viral transmission.
- Conditions
- Compliant Behavior, Self-Control, Impulsive Behavior
- Trial name
- NCT05031559
- Testing
- Episodic Future Thinking, Compassion Training
- Where
- United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Monash University
Child Development Disorders, Pervasive
Randomized Trial of Parent Training for Young Children With Autism
The purpose of this 24 week study is to determine whether a new Parent Training program is effective in reducing disruptive behaviors in young children with pervasive developmental disorders.
- Trial name
- RUBI (NCT01233414)
- Testing
- Parent Training, Psychoeducational Program
- Where
- 6 sites in United States
- Volunteers
- 180 people
- Sponsor
- Yale University
Spinal Cord Injury, Acute, Professional-Patient Relations
Effectiveness of Psycho-emotional Support in Acute Spinal Cord Injury. ESPELMA Project
The purposes of the ESPELMA project are twofold: 1) To increase acute spinal cord injury patients' satisfaction with treatment while hospitalization and 2) To increase mastery among rehabilitation professionals with regard to the…
- Conditions
- Spinal Cord Injury, Acute, Professional-Patient Relations, Sensitivity Training Groups, Patient Non-Compliance
- Trial name
- ESPELMA (NCT01889940)
- Testing
- Training for professionals (Spinal Cord Injury Unit staff).
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Hypertension
Group Visits to Improve Hypertension Management
This study investigates group medical visits as a quality improvement strategy for hypertension. It studies group visits in which patients see their own primary care provider together with other patients who have hypertension.
- Trial name
- NCT00129493
- Testing
- Group medical visits
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- US Department of Veterans Affairs
Bipolar Disorder
Customized Medication Adherence Enhancement for Adults With Bipolar Disorder
This study is a modular intervention that is intended to improve treatment adherence among individuals with bipolar disorder on atypical antipsychotic therapy who have been identified as having treatment adherence problems.
- Trial name
- UH CAE (NCT00830310)
- Testing
- Psychoeducation module, Substance use module, Improved communication/rapport with provider module
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University Hospitals Cleveland Medical Center
Diabetes Mellitus, Type 1, Noncompliance, Patient
Feasibility and Effectiveness of Real-time, Remote Continuous Glucose Monitoring in Adolescents With Poorly Controlled Type 1 Diabetes
Adolescents with Type 1 Diabetes (age 13-18 years, T1D duration >6 months managed on insulin) and poor glycemic control will wear a blinded CGM to obtain baseline data.
- Trial name
- NCT04540536
- Testing
- Continuous Glucose Monitoring, Secure texting
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Patient Non-compliance
Promoting Engagement in the Drug Resistant TB/HIV Care Continuum in South Africa
The goals of this research are to understand adherence and retention in care for multi-and extensively drug-resistant tuberculosis (M/XDR-TB) patients using a mixed methods approach.
- Trial name
- PRAXIS (NCT03162107)
- Where
- South Africa
- Volunteers
- 199 people
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
Schizophrenia
Patient-Centered Medication Adherence Intervention for Schizophrenia
Efficacious antipsychotic medication treatments for schizophrenia are available; however , antipsychotic regimens frequently do not achieve their potential because of poor medication adherence.
- Trial name
- AMAIS (NCT00144027)
- Testing
- Antipsychotic medication adherence intervention
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- US Department of Veterans Affairs
Patient Non-adherence
Adherence to Lenalidomide Treatment in Multiple Myeloma - Prevalence, Characteristics and Clinical Significance
we intend to evaluate the association between non-adherence to Lenalidomide in Multiple Myeloma (MM) patients and overall response rates and time to progression (TTP).
- Trial name
- NCT02733224
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
Patient Noncompliance
Customized Adherence Enhancement Plus Long-acting Injectable Antipsychotic
Psychotropic medications are a cornerstone of treatment for individuals with schizophrenia and schizoaffective disorder, however rates of full or partial non-adherence can exceed 60%.
- Trial name
- CAE-L (NCT01152697)
- Testing
- haloperidol decanoate, haloperidol, Customized Adherence Enhancement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University Hospitals Cleveland Medical Center
Hypertension
Pharmacy Implementation Trial: Adherence to Antihypertensive Therapy
The purpose of this study is to determine the effectiveness of maximal support of community pharmacies to implement a pharmaceutical care model for establishing and - if necessary - improving adherence to antihypertensive…
- Trial name
- NCT00460343
- Testing
- extensive implementation programme, control
- Volunteers
- 57 people
- Sponsor
- Radboud University Medical Center
Older Adults (65 Years and Older)
Quantifying the Attentive Behaviors of Older Adults During Over-the-counter Drug Selection
Per-capita consumption of medication is higher in older adults than any other sector of the population. In fact, it has been estimated that although older adults comprise 13% of the population they take 34% of all prescriptions…
- Trial name
- NCT02188134
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Medication Errors
Improving Parental Understanding of Medication Instructions Through a Pictogram-Based Intervention
Liquid medication administration errors are common, and place children at risk for adverse events. Caregivers with low socioeconomic status (SES), low education and poor health literacy skills are at increased risk for errors.
- Trial name
- NCT00537433
- Testing
- Pictogram
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Bipolar Disorder, Schizophrenia
Event Marker Ingested To Trigger Event Recorder 3.0 Psychiatry Study
Feasibility study of using a digital health feedback system (DHFS) to monitor medication-taking and physiologic and behavioral parameters in patients with bipolar disorder or schizophrenia.
- Trial name
- EMITTER3PSY (NCT01804257)
- Testing
- Digital Health Feedback System
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Proteus Digital Health, Inc.
Disruptive Behavior, Aggression
Cognitive-Behavioral Therapy for Disruptive Behavior in Children and Adolescents
This is a randomized controlled study of cognitive-behavioral therapy (CBT) for disruptive behavior such as irritability, anger and aggression in children and adolescents.
- Conditions
- Disruptive Behavior, Aggression, Anger, Irritability
- Trial name
- RDoC-CBT (NCT01965184)
- Testing
- Cognitive-Behavioral Therapy for Anger and Aggression, Supportive Psychotherapy (SPT)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Yale University
Patient Noncompliance, Health Literacy
Impact of Health Literacy and Other Factors on Glaucoma Patient Adherence in South India
The purpose of this study is to determine how health literacy impacts glaucoma patient adherence (as measured by following up with the doctor) in Tamil Nadu, India.
- Conditions
- Patient Noncompliance, Health Literacy, Glaucoma
- Trial name
- NCT00694876
- Where
- India
- Volunteers
- 250 people
- Sponsor
- Robin, Alan L., M.D.
Patient Non-Compliance, Schizophrenia and Related Disorders
Study on Psychoeducation Enhancing Results of Adherence in Schizophrenia
Background: Psychosis in the spectrum of schizophrenia (PSS) are severe mental disorders, with a high impact on disability and participation. Poor adherence to pharmacotherapy negatively impacts on the course and outcome of PSS.
- Trial name
- SPERA-S (NCT01433094)
- Testing
- Falloon et al. Psychoeducation Program, Generic Treatment
- Where
- 8 sites in Italy
- Volunteers
- 112 people
- Sponsor
- University of Cagliari