Clinical trials: Patient Outcomes
Inflammatory Disease, Immune System Disorder
Cross-condition Validation of the Steroid PRO
Testing a questionnaire about treatment with steroids for skin, lung or gastric conditions
- Conditions
- Inflammatory Disease, Immune System Disorder, Gastrointestinal Diseases, Dermatologic Disease
- Trial name
- NCT06314451
- Testing
- Cognitive Interview
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Patient Reported Outcome Measures, Recovery of Function
FIT Study (Functional Outcomes In Trauma Study)
Why? There is not much information in the UK on how well patients who sustain major trauma function afterwards. Major trauma is defined as significant injuries with a calculated 'injury severity score' (ISS) over 15.
- Conditions
- Patient Reported Outcome Measures, Recovery of Function, Rehabilitation, Disability Evaluation
- Trial name
- NCT04074382
- Testing
- Online Questionnaires, Qualitative Interviews
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Trauma, Shock, Traumatic
Discriminant Ability of the Shock Index, Modified Shock Index, and Reverse Shock Index Multiplied by the Glasgow Coma Scale on Mortality in Adult Trauma Patients: A PATOS Study
We evaluated a cohort of adult trauma patients transported to emergency departments. The first vital signs were used to calculate the SI, MSI, and rSIG.
- Conditions
- Trauma, Shock, Traumatic, Morality
- Trial name
- NCT05549986
- Testing
- Observational
- Volunteers
- 105,641 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
HIV/AIDS
Outcomes of Differentiated Models of Antiretroviral Treatment (ART) Provision
The aim of this study is to evalulate the effectiveness and cost-effectiveness of three models of ART provision for stable ART patients.
- Trial name
- [MMD] (NCT03438370)
- Testing
- Three monthly ART supply at CAGs, Six monthly ART supply at outreaches
- Where
- Lesotho
- Volunteers
- 5,760 people, healthy volunteers welcome
- Sponsor
- Equip, Lesotho
Infertility, Endometriosis
Comparison Elagolix vs Depot Leuprolide Prior to Frozen Embryo Transfers in Patients With Endometriosis
Patients who have been previously surgically diagnosed with endometriosis and have embryos predicted to be euploid after in vitro fertilization will be divided into 2 groups via randomization.
- Trial name
- NCT04445025
- Testing
- Elagolix 200 MG, Leuprolide Acetate 3.75 MG/ML, Lab work
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Reproductive Medicine
Kidney Transplant Rejection
Evaluation of Patient Outcomes From the Kidney Allograft Outcomes AlloSure Registry
This is an observational study to evaluate safety and efficacy outcomes in renal transplant recipients in whom post-transplant care is managed using AlloSure®.
- Trial name
- KOAR (NCT03326076)
- Testing
- Donor-derived cell-free DNA (AlloSure®), Standard care, Peripheral blood gene expression profiling (AlloMap Kidney)
- Where
- 72 sites in United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- CareDx
Outcomes
Prognostic Value of Preoperative 6-Minute Walk Test for Laparoscopic Gastrointestinal Surgery
6-minute walk test (6MWT) is widely used in cardiopulmonary surgery as a prognostic marker. This prospective cohort study aims to find whether 6MWT will be a good prognostic factor for patients who will undergo laparoscopic…
- Trial name
- NCT03711526
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cataract Senile, Endophthalmitis
Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus Levofloxacin
Comparative safety study of intracameral levofloxacin versus moxifloxacin for postoperative infection prophylaxis
- Conditions
- Cataract Senile, Endophthalmitis, Antibiotic Side Effect, Safety Issues
- Trial name
- NCT04403334
- Testing
- Levofloxacin Ophthalmic, Moxifloxacin Ophthalmic
- Where
- Philippines
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Peregrine Eye and Laser Institute
Ingrown Toenail
P : Ingrown Toenail Patient I : Bird Flap Surgery C : Noel Winograd Method O : Recurrence, Complications, Functional Outcome, Pain,
The treatment of ingrown toenails is highly diverse, with numerous surgical techniques described in the literature alongside conservative approaches.
- Trial name
- ITN (NCT06862232)
- Testing
- Modified Winograd "Bird Flap" Technique, Classic Winograd Technique, Modified Noel Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kutahya City Hospital
Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia
Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS
This phase II trial studies the effect of venetoclax together with busulfan, cladribine, and fludarabine in treating patients with high-risk acute myeloid leukemia or myelodysplastic syndrome who are undergoing stem cell…
- Conditions
- Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome
- Trial name
- NCT04708054
- Testing
- Busulfan, Cladribine, Fludarabine Phosphate
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Aortic Valve Disease
Optimizing Health Outcomes in Patients With Symptomatic Aortic Valve Disease
Disease of the aortic heart valve is both common and progressively disabling, with no effective medical treatment. In November 2011, the United States Food and Drug Administration (U.S.
- Trial name
- PCORI-AVR (NCT02266251)
- Where
- United States
- Volunteers
- 273,365 people, healthy volunteers welcome
- Sponsor
- Duke University
Quality of Life
Transplantoux Health Evaluation Study
The primary aim is to evaluate the short- and long-term effect of the 'Transplantoux' exercise training intervention in solid organ transplant recipients with matched control sample of transplant recipients in view of selected…
- Trial name
- THES (NCT02533245)
- Testing
- Home-based indiviualized exercise training program, Supervised group training sessions, Climb of the Mont Ventoux
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Peri-Implantitis
ICG-PDT, Periimplantitis, Diabetes Mellitus
In this study, the effect of photodynamic therapy (indocyanine green mediated) on the clinical, biological and inflammatory aspects was assessed in diabetic patients having peri-implantitis
- Trial name
- NCT04833569
- Testing
- ICG-PDT, peri-implant mechanical debridement
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Saud University
Osteo Arthritis Knee
Incorporating Patient-Reported Outcomes Into Shared Decision Making With Patients With Osteoarthritis of the Hip or Knee
Osteoarthritis (OA) of the knee constitutes a major public health problem. Treatment options for knee OA range from lifestyle changes to pharmacological management to total knee replacement surgery.
- Trial name
- NCT04805554
- Testing
- Joint Insights decision aid
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Sleep Apnea, Hypersomnia
Patient Outcomes in Unattended and In- Lab Polysomnography
This randomized controlled study will directly evaluate whether unattended polysomnography (level 2 sleep study) in individuals referred for sleep apnea or hypersomnia, including those with comorbidities of insomnia and…
- Trial name
- NCT05230394
- Testing
- Attended Polysomnography in the Lab, Unattended Polysomnography in the Home
- Where
- Canada
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Cerebra Medical
Carpal Tunnel Syndrome (CTS)
Pain Neuroscience Education Versus Kinesio Tape on Functional Outcomes in Patients With Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is one of the most common compressive neuropathies of the upper limb, characterized by pain, numbness, and functional impairment due to median nerve compression at the wrist.
- Trial name
- CP syndrome (NCT07539480)
- Testing
- group A: pain neuroscience education (PNE), group B: Patients receive Kinesio Taping
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Middle East University
Patient Satisfaction
Patient Satisfaction and Clinical Experience of Dentists
Rehabilitation of the edentulous patients has always been a challenge. The success of this treatment modality is not only affected by the patients' acceptance of his new dentures, but on his ability to use them which depends to a…
- Trial name
- NCT05076968
- Testing
- Complete denture fabrication
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Covid19, Corona Virus Infection
Functional Recovery of Hospitalised Patients With COVID-19: The COREG Extension Study
Older adults and those with chronic underlying health conditions are the most susceptible to COVID-19 and its complications. Although there has been a rapid response to studying the effects of COVID-19 in the acute stages, little…
- Conditions
- Covid19, Corona Virus Infection, Mobility Limitation, Frailty
- Trial name
- NCT04602260
- Where
- Canada
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- McMaster University
Female Breast Carcinoma, Healthy Subject
Technology and Health Communication in Improving Health Outcomes in Patients Scheduled for Mammography
This pilot clinical trial studies how well technology and health communication works in improving health outcomes in patients scheduled for mammography screening.
- Trial name
- NCT04290585
- Testing
- Questionnaire Administration, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center