Clinical trials: Patient Preference, open to volunteers
Covid-19 Vaccination
Effect of Messaging on Pragmatic Outcomes Within an Integrated Healthcare System
COVID-19 vaccination among patients at high risk for severe disease has declined in the United States since 2022. Prior research, including discrete choice experiments (DCEs), has demonstrated that vaccine preferences are…
- Trial name
- EMPOWeR (NCT07838038)
- Testing
- Vaccine choice message, Vaccine choice + platform-framed message, Vaccine choice + HCP trust-framed message
- Where
- United States
- Volunteers
- 1,300,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Acute Appendicitis
Patient Choice Between Antibiotics and Appendectomy in Uncomplicated Appendicitis (FRENCH 47 - ALACARTE)
The ALACARTE study evaluates a strategy in which patients with acute uncomplicated appendicitis are given the choice between appendectomy and antibiotic therapy alone.
- Trial name
- ALACARTE (NCT07857252)
- Testing
- Shared decision-making, amoxicillin-clavulanate, Appendectomy
- Where
- France
- Volunteers
- 560 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Dental Caries
Er:YAG Laser for Dental Cavity Preparation
The goal of this clinical trial is to compare Er:YAG laser cavity preparation with conventional rotary instruments in adults who have permanent premolars planned for extraction as part of orthodontic treatment.
- Trial name
- NCT07831720
- Testing
- Er:YAG Laser, Conventional Rotary Cavity Preparation
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ho Chi Minh City Odonto-Stomatology Hospital
Family Members, Critical Illness
The VIP3 (Very Old Intensive Care Patients) Study: Family Involvement in Treatment Decisions for Old ICU Patients
The demographics of the global population is changing with increasing numbers of elderly and co-morbid patients. As a result, more elderly patients will be admitted to the Intensive Care Unit (ICU), which will bring several…
- Conditions
- Family Members, Critical Illness, Frailty, Communication
- Trial name
- VIP3 (NCT07035951)
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- St George's, University of London
Solid Tumors
Physician and Patient Preferences for Cell Therapies in Advanced Solid Tumors
Cell therapies - including chimeric antigen receptor T-cell (CAR-T) therapy, tumor-infiltrating lymphocyte (TIL) therapy, T-cell receptor-engineered T-cell (TCR-T) therapy, and natural killer (NK) cell therapy - are emerging…
- Trial name
- NCT07813000
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 1,020 people
- Sponsor
- Zhejiang University
Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Rehabilitation
Factors Associated With Acceptance of Home-Based Pulmonary Telerehabilitation in COPD
Pulmonary rehabilitation improves symptoms, exercise capacity, and quality of life in people with chronic obstructive pulmonary disease (COPD), but access and participation may be limited by travel, organizational, logistical…
- Trial name
- ACCEPT-TR (NCT07747571)
- Testing
- No intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- ADIR Association
Neoplams, Physician-Patient Relations
One-Page Truth-Telling Aid for Cancer Disclosure
The goal of this clinical trial is to learn whether a one-page communication aid can improve communication between physicians and patients with cancer during cancer-related truth-telling consultations.
- Conditions
- Neoplams, Physician-Patient Relations, Communication Research, Disclosure
- Trial name
- NCT07730164
- Testing
- One-Page Truth-Telling Aid, Blank Sheet
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Chang Gung University
Patient Preference
Tradeoffs in Patient Decision Making About Rectal Cancer Treatment: Benefits Compared to Quality Of Life.
This study is aiming to look into patients' treatment preferences and their socio economic background as well as the exploration of thought processes leading to these preferences.
- Trial name
- Pathos (NCT04925154)
- Testing
- The only intervention will be the information brochure that will be given after the first questionnaire.
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Treatment-Resistant Major Depressive Disorder
Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
The goal of this pilot clinical trial is to learn whether it is feasible to individually tailor psilocybin-assisted psychotherapy (PAP) for people with treatment-resistant depression (TRD) based on their personal preferences.
- Trial name
- PPP (NCT07373535)
- Testing
- Psilocybin 25mg, Music-centered psilocybin-assisted therapy, Mindfulness-centered psilocybin-assisted therapy
- Where
- 2 sites in Canada
- Volunteers
- 16 people
- Sponsor
- Kyle Greenway
Health Care Costs, Delivery of Health Care
Advancing Decisions About Virtual Service Encounters
Expanded availability of virtual care encounters in Primary Care provides new opportunities to improve Veterans' outcomes by aligning encounter modalities with their needs and preferences.
- Trial name
- ADViSE (NCT06539988)
- Testing
- Clinician Coaching Sessions, Personalized text messages to patients
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- VA Office of Research and Development
Gynecologic Cancers
Interest in Nighttime Day Hospital Chemotherapy Infusions Among Gynecologic Cancer Patients
This observational study aims to assess the interest of patients with gynecologic cancers in a nighttime Day Hospital service for the administration of long-duration chemotherapy infusions.
- Trial name
- CHeMoON (NCT07483905)
- Testing
- online survey
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans 3.0
Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Hypertension
- Trial name
- EMPOWER (NCT07356479)
- Testing
- EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- VA Office of Research and Development
Goals of Care, Patient Preference
Eliciting Informed Goals of Care in Elderly Patients
Patient-centered medical care considers a patient's values and goals for their health and well-being. Healthcare providers use this information to formulate a medical care plan that is aligned with these expectations.
- Conditions
- Goals of Care, Patient Preference, End of Life
- Trial name
- ASKMEGOC (NCT06002113)
- Testing
- GOCD Tool, Usual care
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Royal Victoria Hospital, Canada
Generalized Anxiety Disorder (GAD)
The Effect of Patient Preference for Treatment Model in Internet Delivered Cognitive Behavior Therapy for Generalized Anxiety Disorder
The goal of this clinical trial is to investigate the effect of allowing patients to choose between two internet-based cognitive behavioral treatments (ICBT) for generalized anxiety disorder (GAD).
- Trial name
- ORIGAMI (NCT07201844)
- Testing
- Metacognitive Internet delivered Cognitive Behavior Therapy, Intolerance of uncertainty based Internet delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 440 people
- Sponsor
- Karolinska Institutet
Acute Stroke
Factors and Preferences in Patient Selection of Rehabilitation Care Following Acute Stroke: A Predictive Correlational Study.
Background and Purpose Patients with stroke have to receive the rehabilitation care after medical condition has stabilized. In recent years, the long-term care policy offers more options available for rehabilitation care after…
- Trial name
- NCT07089095
- Testing
- questionnaire
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Informed Consent, Preference, Patient
Patient Preferences on Same-day Bilateral Intravitreal Dexamethasone Injections
Intravitreal injections with dexamethasone implant (Ozurdex®) provide a reasonable and long-lasting treatment option in the cases of diabetic macular edema, as well as macular edema resulting from retinal vein occlusion and…
- Trial name
- NCT06894017
- Testing
- Ozurdex (dexamethasone)
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cancer, Gastrointestinal Cancer
Quality of Care in Relationship to Aborted Cancer Surgery
Surgery is often a central curative treatment for gastrointestinal tumors. Surgical treatment of diagnosed cancer tumors is decided after a comprehensive assessment of the patient's physical status, radiological assessments and…
- Trial name
- NCT05808712
- Testing
- validation
- Where
- 2 sites in Sweden
- Volunteers
- 350 people
- Sponsor
- Linkoeping University
IUD, Analgesia
TENS Unit for Analgesia During IUD Insertion
Subjects will be screened over the phone or in Tufts GYN clinic for participation in the study. If eligible and interested in participating, written informed consent (and assent if applicable) will be obtained.
- Conditions
- IUD, Analgesia, Patient Preference, Pain, Acute
- Trial name
- NCT06240260
- Testing
- TENS (transcutaneous electrical nerve stimulation) unit, Standard care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Patient Preference
CT-Angiography Plaque Characteristics and Events in Deferral Patients by Invasive Fractional Flow Reserve
Fractional flow reserve (FFR)-guided PCI for chronic coronary syndromes (CCS) is reported to improve the outcomes compared with angiography-guided PCI.
- Trial name
- CAPTURE (NCT06508697)
- Testing
- invasive coronary angiography (ICA) with fractional flow reserve (FFR) pressure measurement
- Where
- Japan
- Volunteers
- 400 people
- Sponsor
- Fujita Health University