Clinical trials: Patient Reported Outcomes, open to volunteers
Hemodialysis
Physical Activity Prescription Program for Hemodialysis Patients
The goal of this clinical trial is to compare the efficacy of a standard intradialytic exercise program (control group) to an individualized, patient-centered, "Move-More" physical activity intervention (intervention group) in…
- Trial name
- Move More (NCT06830993)
- Testing
- "Move More" Personalized Exercise Program, Intradialytic Exercise Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arizona
Prospective
A Register Based Prospective Study During Implementation of a New Cup
In a prospective register-based study, we aim to evaluate the implant survival, clinical outcomes and X-ray findings by following a cohort of patients operated with the Trident II cup.
- Trial name
- NCT04350255
- Testing
- Total hip arthroplasty
- Where
- Sweden
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Dental Implant, Implant Therapy
Do Immediate Digital Workflows Increase Patient Value?
This two-center randomized controlled trial will evaluate whether an immediate digital posterior implant workflow provides greater patient-defined value than a delayed digital workflow in adults requiring single posterior implant…
- Conditions
- Dental Implant, Implant Therapy, Immediate Dental Implant Placement, Delayed Implant
- Trial name
- ITI PROM RCT (NCT07656597)
- Testing
- Immediate digital posterior implant workflow, Delayed digital posterior implant workflow
- Where
- 2 sites in Germany, Hong Kong
- Volunteers
- 50 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
COPD, Nurse-Patient Relations
Effectiveness of Motivational Interviewing in Patients With COPD
To determine the effect of motivational interviewing based on Pender's health promotion model on patient-reported outcomes in patients with COPD.
- Trial name
- NCT06783582
- Testing
- Motivational interviewing based on Pender's health promotion model
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zeynep Yildirim
Frailty, Delirium Confusional State
Patients With Long-stay at ICU: Factors and Evaluation - Feasibility Study
Every year, many critically ill patients are admitted to an intensive care unit (ICU). Most stay only a few days, but a smaller group stays much longer.
- Conditions
- Frailty, Delirium Confusional State, Persistent Critical Illness, Post-Intensive Care Syndrome
- Trial name
- LIFE-ICU (NCT07851974)
- Where
- 4 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Uppsala University
Osteoarthritis, Knee
Effects of Different Collagen Formulations on Knee Osteoarthritis
The purpose of this study is to evaluate and compare the effects of two different collagen supplement formulations on pain, physical function, and overall quality of life in adults with knee osteoarthritis.
- Trial name
- NCT07800780
- Testing
- 10g Hydrolyzed Collagen, 5g Bioactive Collagen Peptide
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Cihangir Türemiş
Diagnosis of Cancer
Eortc MoBilE Device (EMBED)
This study is a longitudinal observational study that will investigate the feasibility of using mobile devices for the assessment of HRQoL and physical activity in adult cancer patients undergoing treatment.
- Trial name
- EMBED (NCT07711080)
- Volunteers
- 137 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Chronic Lymphocytic Leukaemia (CLL), Multiple Myeloma (MM)
Developing a Patient-Reported Outcome (PRO) Screening Measure for Infections and Measuring Quality of Life in Hematological Patients With Secondary Immunodeficiency (SID) Across the Treatment Trajectory - The PRO SID Project
The goal of this observational study is to improve the treatment of hematological patients with secondary immunodeficiency (SID) by developing a patient-reported outcome (PRO) instrument to detect clinically diagnosed infections.
- Conditions
- Chronic Lymphocytic Leukaemia (CLL), Multiple Myeloma (MM), Secondary Immunodeficiency (SID)
- Trial name
- PRO-SID (NCT06821880)
- Where
- 5 sites in Austria, Germany
- Volunteers
- 120 people
- Sponsor
- Medical University Innsbruck
Lower Lip Tissue Loss, Cancer
Functional and Aesthetic Outcomes Following Lower Lip Reconstruction
This retrospective study, aims to evaluate the functional and aesthetic results of lower lip reconstructions, incorporating both patient experiences and the analysis of physicians and surgeons working on facial issues (plastic…
- Trial name
- REFEPLI (NCT07298070)
- Testing
- Patient-Reported Outcome Questionnaire (post-operative)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hôpital NOVO
Facial Vascularized Composite Allotransplantation, Functional Recovery
Facial Vascularized Composite Allotransplantation: A Study Evaluating Safety, Functional Outcomes, and Patient-Reported Psychosocial Outcomes
The primary objective of this study is to evaluate the 5-year (60-month) allograft survival rate of facial vascularized composite allotransplantation performed under the standardized CONSORT clinical protocol.
- Trial name
- NCT07810764
- Testing
- Facial Vascularized Composite Allotransplantation (VCA)
- Where
- 9 sites in United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Breast Neoplasms, Breast Cancer
PROVIDENCE - Prospective Non-interventional Study (NIS) to Examine Patient-reported Outcomes and Real-world Clinical Data in Patients With HER2-positive, HER2-low or HER2-ultralow Unresectable or Metastatic Breast Cancer Treated With Trastuzumab Deruxtecan
This is a prospective non-interventional, multicenter study observing patient reported outcomes as well as real-world efficacy and safety of trastuzumab deruxtecan (T-DXd) in patients with documented Human epidermal growth factor…
- Conditions
- Breast Neoplasms, Breast Cancer, Neoplasm Metastasis
- Trial name
- PROVIDENCE (NCT05573893)
- Where
- 109 sites in Germany
- Volunteers
- 800 people
- Sponsor
- AstraZeneca
Benign Prostatic Hyperplasia
Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia Using Patient-Reported Outcomes
The goal of this project is to use newly developed patient-reported outcomes to improve the clinical care of patients with benign prostatic hyperplasia.
- Trial name
- NCT05898932
- Testing
- Medical Management, Surgical Management
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Well-Being, Psychological
Evaluation of Patient-Reported Outcomes Measurement Information System (PROMIS)-29 v2.1 for Postpartum Women
There is no widely used, statistically validated assessment for physical and mental health for the short- to medium-term in a postpartum population.
- Trial name
- NCT06002763
- Testing
- PROMIS-29 v2.1 (Patient-Reported Outcomes Measurement Information System), WHOQoLBREF (World Health Organization Quality of Life Brief Version), EQ-5D-3L1 (not an acronym)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Meniscus Tear
Novel Bioactive Sleeve on Pain and PROMs
A novel bioactive sleeve will be compared to a placebo sleeve with a similar look and feel to assess pain outcomes, patient reported outcome measures, and effectiveness of healing based on range of motion.
- Trial name
- NCT06041321
- Testing
- Reparel Sleeve
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs)
Validation of the EQ-5D-Y-3L and EQ-5D-Y-5L for Paediatric Patients in China
The goal of this observational study is to validate the EQ-5D-Y-3L and EQ-5D-Y-5L in measuring health-related quality of life (HRQoL) for paediatric patients with different health conditions in China.
- Conditions
- Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs), Pneumonia Childhood, Neuroblastoma (NB)
- Trial name
- NCT06873672
- Where
- China
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital
Hip Injuries and Disorders, Hip Fractures
Intramedullary Nail Versus Hip Arthroplasty in Unstable Trochanteric Hip Fractures
A hip fracture is a large burden to the patient with increased mortality, pain and increased need for daily assistance. Trochanteric fractures of the femur (FTF) represents about 35% of the hip fractures.
- Trial name
- TUFHIPRCT (NCT04868305)
- Testing
- Intramedullary nail, Hip arthroplasty
- Where
- Norway
- Volunteers
- 170 people
- Sponsor
- Helse Stavanger HF
Friedreich Ataxia
Patient-reported, Health Economic and Psychosocial Outcomes in Friedreich Ataxia
The PROFA study is an international, multi-centric observational and validation study to assess the patient-reported, psychosocial and economic outcomes of patients with Friedreich Ataxia (FA).
- Trial name
- PROFA (NCT05943002)
- Where
- 6 sites in Austria, France and 1 more
- Volunteers
- 200 people
- Sponsor
- German Center for Neurodegenerative Diseases (DZNE)
Palliative Care Referral, Advanced Cancer
Electronic Patient Reporting of Symptoms and Unmet Needs to Connect Patients With Advanced Cancer to Palliative Care Services
This study is testing whether electronic surveys can help patients with advanced cancer report their symptoms and care needs so their doctors can connect them to palliative/supportive care services sooner.
- Conditions
- Palliative Care Referral, Advanced Cancer, Palliative Care, Health Services, Metastatic Cancer (Different Solid Tumour Types)
- Trial name
- PRO-CONNECT (NCT07195513)
- Testing
- ePRO-Directed Referral and Navigation to Palliative/Supportive Care, ePRO Symptom Monitoring with Usual Palliative Care Referral
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
TNBC - Triple-Negative Breast Cancer
Real-world Patient-reported Outcome of Sacituzumab Govitecan in Chinese Metastatic Breast Cancer
A real-world, multicenter, prospective study to evaluate the patient-reported outcome in Chinese patients who received sacituzumab govitecan or chemotherapy of the physician's choice for metastatic breast cancer progressing on…
- Trial name
- NCT07551050
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Fudan University
Stroke, Stroke, Acute Ischemic
NeuroAiD Patient-Reported Outcomes in Patients With Mild to Moderate Ischemic Stroke
This is a randomized, controlled, open-label study of MLC901 (NeuroAiD™ II) in patients with mild to moderate ischemic stroke. Eligible participants will be randomized in a 1:1 ratio to receive MLC901 in combination with standard…
- Conditions
- Stroke, Stroke, Acute Ischemic, Stroke, Ischemic, Stroke, Cryptogenic
- Trial name
- NAiD-PRO (NCT07828210)
- Testing
- MLC901, Standard treatment for acute ischemic stroke
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- EVD Pharmacy and Medical Company Limited