Clinical trials: Patient Specific Implant
Fibula / Surgery, Surgical Flaps
Novel Application of a Low-cost Alternative to Patient Specific Implants (PSI) in Mandibular Free Fibula Flap Reconstruction by Reverse Engineering of Stock Plates: A Pilot Validation Study
Stock reconstruction plates have been used for decades and represent a tried-and-true alternative to custom plating. Stock plates are readily available, are cost effective, and can be accurately bent before surgery, particularly…
- Conditions
- Fibula / Surgery, Surgical Flaps, Computer-Aided Design, Mandibular Reconstruction* / Methods
- Trial name
- NCT05672056
- Testing
- Computer guided placement of a stock plate pre-bent on a 3D printed model
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ridge Augmentation
Assessment of Digital and Clinical Workflow Using Patient Specific Sticky Bone /Implant Housing PEEK Shell in Anterior Atrophic Maxilla: A Case Series
10 Patients having horizontally deficient anterior maxillary areas will be recruited and a preoperative CBCT will be done. The plan is to graft the defective ridges with simultaneously placing dental implants using a PEEK shell…
- Trial name
- NCT05624697
- Testing
- sticky bone housed in PEEK Shell
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Orbital Floor Reconstruction, PEEK IMPLANTS
Patient-specific PEEK Implants for Post-maxillectomy Orbital Floor Reconstruction
The study aims to evaluate the utilization of Patient-specific PEEK implantsd in reconstruction of orbital floor after maxilla ablation surgery
- Conditions
- Orbital Floor Reconstruction, PEEK IMPLANTS, MAXILLECTOMY
- Trial name
- NCT07789392
- Testing
- Patient-specific PEEK implants
- Where
- Egypt
- Volunteers
- 6 people
- Sponsor
- Alexandria University
Partially Edentulous Patients, Implant Stability
Comparative Clinical Study of Implant Stability and Peri-implant Bone Loss in Two Implant Designs
This clinical study was conducted to evaluate the effect of different dental implant designs on implant stability and peri-implant bone levels during the early healing phase.
- Conditions
- Partially Edentulous Patients, Implant Stability, Peri-implant Marginal Bone Loss
- Trial name
- NCT07557836
- Testing
- Double-threaded straight-body dental implant, Triple-threaded conical-body dental implant
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Career Postgraduate Institute of Dental Science and Hospital Lucknow
Osteotomy, Malalignment, Bone
Comparison Between TOMOFIX and BodyCAD Fine Osteotomy
This is a single centre, randomised, patient blinded pilot study that will assign 40 participants with medial knee osteoarthritis undergoing medial opening wedge high tibial osteotomy (MOWHTO) to either current standard of care…
- Conditions
- Osteotomy, Malalignment, Bone, Osteoarthritis, Knee
- Trial name
- NCT06250530
- Testing
- High tibial osteotomy using TOMOFIX, High tibial osteotomy using BodyCAD
- Volunteers
- 40 people
- Sponsor
- Western University, Canada
Osteoarthritis
Study Comparing Fit of the iTotal Versus Standard Total Knee Implants
This study compares intraoperative fit of the patient-specific iTotal knee replacement to other standard knee replacement implants
- Trial name
- NCT01861028
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Restor3D
Mandibular Dislocation
Evaluation of Patient Satisfaction Using Autogenous Inlay (Sandwich) Eminoplasty Versus Patient Specific Poly Ether-ether Ketone (PEEK) Onlay Implant
Aim of the study: The aim is minimize morbidity in treatment of TMJ dislocation. Hypothesis: Alternate hypothesis that treatment tmj dislocation with PEEK eminoplasty will be more efficient than using autogenous inlay technique…
- Trial name
- NCT03994692
- Testing
- PEEK eminoplasty, autogenous onlay grafting eminoplasty
- Volunteers
- 7 people
- Sponsor
- Cairo University
Immediate Implant Placement in Mandibular Molar Extraction Sockets
Computer Guided Immediate Implant Placement in Mandibular Molars Using Patient Specific 3D Printed Polylactic Acid Graft Versus Conventional Immediate Implant Placement With Xenograft
This randomized controlled clinical trial will evaluate a computer-guided immediate implant placement technique in non-restorable mandibular molars using a patient-specific 3D-printed polylactic acid (PLA) graft and implant…
- Trial name
- RCT (NCT07774052)
- Testing
- Patient-Specific 3D-Printed PLA Socket Guide and Root-Form Scaffold, Conventional Immediate Implant Placement
- Where
- Egypt
- Volunteers
- 17 people
- Sponsor
- Mahmoud Fawzy Mahmoud Mohamed
T-cell Lymphoma, NK-Cell Lymphoma
A Registry for People With T-cell Lymphoma
The purpose of this registry study is to create a database-a collection of information-for better understanding T-cell lymphoma.
- Conditions
- T-cell Lymphoma, NK-Cell Lymphoma, T-cell Prolymphocytic Leukemia, T-cell Large Granular Lymphocytic Leukemia
- Trial name
- NCT05978141
- Testing
- Optional Blood Sample and Nail Sample
- Where
- 26 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Retrognathia, Malocclusion, Angle Class II
Maxillary Patient Specific Implants in Bimaxillary Orthognathic Surgery
Orthognathic surgery is a type of jaw surgery where a surgeon cuts the bones of the upper and lower jaw and places them better. There are two ways they can put the bones in the correct place and keep them in place after the…
- Trial name
- NCT06297109
- Testing
- Patient-specific implants, Conventional mini-plates
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Temporal Hollowing
Patient Specific PEEK Implants for Immediate Restoration of Temporal Fossa After Maxillary Reconstruction With Temporalis Muscle Flap
Study conducted on patients with major maxillary defects indicating the need of reconstruction with full temporalis muscle flap; or any lesion indicating major maxillary resection and immediate reconstruction with total…
- Trial name
- NCT05240963
- Testing
- Temporal PEEK implant
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cartilage Lesion
A Talus Implant in Patients Between 20-60 Years of Age Followed up for a Minimum of 2 Years After Surgery
The project will investigate safety, feasibility and efficiency when using Episurf Episeal talus implant in patients with osteochondral ankle injuries.
- Trial name
- NCT06932380
- Testing
- Talus prosthesis
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Vestre Viken Hospital Trust
Craniofacial Surgery, Virtual Surgical Planning
Accuracy of Virtual Surgical Planning and Patient Specific Implants in Craniomaxillofacial Reconstruction
The sample will consist of 10 patients who will need reconstruction of craniomaxillofacial deformities and defects. The patients will be operated in the Maxillofacial and Plastic Surgery Department, Faculty of Dentistry…
- Trial name
- NCT06970730
- Testing
- virtual surgical planning and patient specific implants in craniomaxillofacial reconstruction
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Hams Hamed Abdelrahman
Chin Microgenia
The Degree of Accuracy of Patient-specific PEEK Implant to Restore Chin Deficiency
computer guided patient-specific PEEK implant will be used to augment patients with chin deficiency or chin asymmetry.
- Trial name
- NCT03577210
- Testing
- augmentation genioplasty
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Osteoarthritis, Hip, Rheumatoid Arthritis
Acetabular Shell Positioning Using Patient Specific Instruments
The proposed study is a double-blinded randomized controlled trial comparing patient specific instruments with solely standardized instruments and pre-operative planning used for the placement of the acetabular cup prosthesis…
- Conditions
- Osteoarthritis, Hip, Rheumatoid Arthritis, Avascular Necrosis
- Trial name
- NCT01791738
- Testing
- Acetabular positioning system
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The Cleveland Clinic
Unspecified Adult Solid Tumor, Protocol Specific, Vascular Access Device Complications
Study Comparing Two Types of Ports in Patients With Cancer Receiving Intravenous Chemotherapy
RATIONALE: Giving chemotherapy drugs through an implanted port reduces the need for multiple needle sticks. It is not yet known whether one type of port is more effective than another in reducing infections and other side effects…
- Trial name
- NCT00607880
- Testing
- vascular access device placement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Cleft Lip and Palate
Patient Specific Implant Versus Miniplates for Advancement of Hypoplastic Maxilla
Distraction osteogenesis is the treatment of choice in management of severe maxillary anteroposterior deficiency allowing for a progressive bone generation and simultaneous expansion of the surrounding scarred soft tissue \&…
- Trial name
- NCT06292234
- Testing
- PSI, Conventional miniplates
- Volunteers
- 20 people
- Sponsor
- Cairo University
Edentulous Alveolar Ridge Atrophy, ATROPHYC EDENTULOUS JAW
Assessment of the Accuracy of Full Digital Workflow in Patient Specific Submerged Subperiosteal Implants: A Case Series Study
custom made subperiosteal implants will be designed using the patients' CT data and will be inserted with the help of a surgical guide and loaded by a screw retained full arch prosthesis. accuracy will be assessed
- Conditions
- Edentulous Alveolar Ridge Atrophy, ATROPHYC EDENTULOUS JAW, Edentulous Maxilla, Edentulous Alveolar Ridge In Mandible
- Trial name
- NCT07014527
- Testing
- Patient specific subperiosteal implants
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Carmustine Implants in Treating Patients With Brain Metastases
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving the drugs in different ways may kill more tumor cells.
- Trial name
- NCT00003878
- Testing
- polifeprosan 20 with carmustine implant, conventional surgery
- Where
- 11 sites in United States
- Sponsor
- New Approaches to Brain Tumor Therapy Consortium
Knee Osteoarthritis
A Prospective Study to Evaluate the iTotal Knee and iPoly XE Tibial Inserts
This study is designed to evaluate the clinical outcomes of subjects who have recently undergone surgery with the iTotal® Cruciate Retaining (CR) Total Knee Replacement System (KRS) who have also had iPoly XE Tibial Inserts…
- Trial name
- NCT03289754
- Testing
- iPoly XE tibial insert with ConforMIS iTotal KRS
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- Restor3D