Clinical trials: Patient-Centered Outcomes Research
Stroke, Ischemic Stroke
Patient-centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research
PROSPER (Patient-centered Research into Outcomes Stroke patients Prefer and Effectiveness Research) is a three year research project to create a national, sustainable model to improve decision-making and patient-centered stroke…
- Trial name
- PROSPER (NCT02146274)
- Where
- United States
- Volunteers
- 1,877 people
- Sponsor
- Duke University
Metastatic Pancreatic Cancer, Unresectable Pancreatic Cancer
EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options
The objective of this study is to improve the chemotherapy decision making process for Latinos with advanced gastrointestinal cancers.
- Conditions
- Metastatic Pancreatic Cancer, Unresectable Pancreatic Cancer, Metastatic Colorectal Cancer
- Trial name
- NCT03602885
- Testing
- Usual chemotherapy education (CE), Chemotherapy education intervention (CEI)
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Diabetes Mellitus
Improving Diabetes Care Through Effective Personalized Patient Portal Interactions
Patient-facing eHealth technologies, such as online patient portals, connect patients with the healthcare system, help them access their health information, and support self-management of health conditions.
- Trial name
- NCT02953262
- Testing
- My HealtheVet Brochure, My HealtheVet Training Guide for Veterans Living with Diabetes, My HealtheVet Group Training
- Where
- 2 sites in United States
- Volunteers
- 275 people
- Sponsor
- VA Office of Research and Development
Obesity
Short- and Long-Term Effects of Antibiotics on Childhood Growth
The objectives of the proposed study are to assess the effects of different types, timing, and amount of antibiotic use in the first two years of life with (Specific Aim 1) body mass index (BMI) and obesity at ages 5 and 10 years…
- Trial name
- ABX (NCT02744846)
- Testing
- Antibiotics exposure
- Volunteers
- 681,739 people
- Sponsor
- Harvard Pilgrim Health Care
Lumbar Spinal Stenosis
Vertos Mild - Post Market Patient Outcomes
This is a single-center study evaluating the outcomes of patients with painful lumbar spinal stenosis who were treated with the mild procedure (minimally invasive lumbar decompression.
- Trial name
- NCT01076244
- Testing
- Minimally Invasive Lumbar Decompression
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Center for Pain Relief, Inc.
Chronic Disease, Patient Outcome Assessment
Consumer Health IT Tools: Impact on Experience, Access, and Outcomes for Patients With Complex Chronic Conditions
Patient use of health IT tools to interact with healthcare providers and delivery systems, including exchanging secure messages with their medical providers and using other web-based tools, has great potential to increase patient…
- Conditions
- Chronic Disease, Patient Outcome Assessment, Electronic Health Records
- Trial name
- NCT02292940
- Volunteers
- 168,477 people
- Sponsor
- Kaiser Permanente
Type 2 Diabetes Mellitus
Impact of Medicaid Health Home on Patients With Diabetes in New York City
Type 2 diabetes is common in the United States; about 1 in 10 people have the disease. Diabetes can cause devastating health events, such as hospitalizations, kidney failure, blindness, amputation, heart attack, stroke, painful…
- Trial name
- NCT02713321
- Where
- United States
- Volunteers
- 96,759 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Sickle Cell Disease
Comparison of Patient Centered Outcomes for People With Sickle Cell Disease in the Acute Care Setting
The Emergency Department has been the standard location where patients with Sickle Cell Disease (SCD) go to seek care for the treatment of acute painful events.
- Trial name
- ESCAPED (NCT02411396)
- Where
- 3 sites in United States
- Volunteers
- 483 people
- Sponsor
- Johns Hopkins University
Depression, Information Dissemination
Community Partners in Care is a Research Project Funded by the National Institutes of Health
CPIC is a community initiative and research study funded by the NIH. CPIC was developed and is being run by community and academic partners in Los Angeles underserved communities of color.
- Conditions
- Depression, Information Dissemination, Social Determinants of Health
- Trial name
- CPIC (NCT01699789)
- Testing
- Quality Improvement Program, Resources for Services Expert Team, Community Engagement and Planning Council
- Where
- United States
- Volunteers
- 1,246 people
- Sponsor
- RAND
Other Cancer, Gastrointestinal Cancer
Symptom Management Implementation of Patient Reported Outcomes in Oncology
Deficits in the management of common symptoms cause substantial morbidity for cancer patients.Because the health care delivery system is structured to be reactive and not proactive, there are missed opportunities to optimize…
- Conditions
- Other Cancer, Gastrointestinal Cancer, Thoracic Cancer, Gynecologic Cancer
- Trial name
- SIMPRO (NCT03850912)
- Testing
- Stakeholder Survey (Control Period), Stakeholder Survey (Intervention Period), Qualitative Interview
- Where
- 6 sites in United States
- Volunteers
- 42,808 people
- Sponsor
- Dana-Farber Cancer Institute
Type 2 Diabetes, Comparative Effectiveness of Glycemia-lowering Medications
A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes
The GRADE Study is a pragmatic, unmasked clinical trial that will compare commonly used diabetes medications, when combined with metformin, on glycemia-lowering effectiveness and patient-centered outcomes.
- Trial name
- GRADE (NCT01794143)
- Testing
- Sulfonylurea (glimepiride), DPP-4 inhibitor (sitagliptin), GLP-1 receptor agonist (liraglutide)
- Where
- 36 sites in United States
- Volunteers
- 7,850 people
- Sponsor
- GRADE Study Group
Post Partum Depression
Improving Outcomes for Low-Income Mothers With Depression
This is a randomized comparative effectiveness trial to improve outcomes among pregnant and post-partum women with symptoms of depression.
- Trial name
- NCT03221556
- Testing
- Engagement-Focused Care Coordination (EFCC), Problem Solving Education (PSE)
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- Boston Medical Center
Attention Deficit and Disruptive Behavior Disorders, Attention Deficit Disorder With Hyperactivity
Effectiveness of the Quotient® ADHD Assessment in a System of Care
The study goal is to examine whether the use of an objective computerized neuroassessment (the Quotient System) for Attention-Deficit/Hyperactivity Disorder (ADHD) is related to improved outcomes among pediatric patients being…
- Trial name
- NCT02094612
- Testing
- Quotient®, Usual Clinic ADHD Care
- Where
- 3 sites in United States
- Volunteers
- 207 people
- Sponsor
- Kaiser Permanente
Physical Disability
Understanding Disparities in Healthcare and Primary Care Provider Quality
The project proposes to fill gaps in the understanding of disparities in healthcare and primary care provider (PCP) quality from the perspectives of adult Medicare beneficiaries with disabilities compared to those without…
- Trial name
- NCT02626910
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Musculoskeletal Pain, Chronic Pain
N-of-1 Trials Using mHealth in Chronic Pain
Chronic musculoskeletal pain is an important problem, and treatments are often prescribed in a "trial and error" fashion. Clinicians prescribe a treatment to a patient and then wait and see if the treatment is successful.
- Trial name
- PREEMPT (NCT02116621)
- Testing
- Trialist Intervention, smartphone
- Where
- 2 sites in United States
- Volunteers
- 215 people
- Sponsor
- University of California, Davis
Concept Mapping Versus Interviews
Concept Mapping as a Scalable Method for Identifying Patient-Important Outcomes
The goal of this study is to improve the methods with which researchers identify patient centered outcomes for use in research. Specifically, the investigators will test the application of concept mapping as compared to…
- Trial name
- VOICe (NCT02792777)
- Testing
- Interviews, Concept Mapping (CM)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Thomas Jefferson University
Treatment Resistant Depression, Major Depressive Disorder
Optimizing Outcomes of Treatment-Resistant Depression in Older Adults
The purpose of this research study is to assess which antidepressants work the best in older adults who have treatment-resistant depression (TRD).
- Conditions
- Treatment Resistant Depression, Major Depressive Disorder, Treatment-Refractory Depression, Late Life Depression
- Trial name
- OPTIMUM (NCT02960763)
- Testing
- Aripiprazole Augmentation, Bupropion Augmentation, Switch to bupropion
- Where
- 5 sites in United States, Canada
- Volunteers
- 742 people
- Sponsor
- Washington University School of Medicine
Metastatic Colorectal Cancer, Metastatic Pancreatic Cancer
Improving Informed Consent for Palliative Chemotherapy
Patients are routinely asked to sign an "informed consent" document prior to starting chemotherapy, indicating they understand the risks and benefits of treatment.
- Conditions
- Metastatic Colorectal Cancer, Metastatic Pancreatic Cancer, Unresectable Pancreatic Cancer
- Trial name
- NCT02282722
- Testing
- Investigational informed consent for chemotherapy, Usual, standard-of-care informed consent for chemotherapy
- Where
- 8 sites in United States
- Volunteers
- 216 people
- Sponsor
- Dana-Farber Cancer Institute
Contraception, Contraception Behavior
Patient-Centered Reproductive Decision Support Tool for Women Veterans
The investigators have developed a web-based decision support tool to help women Veterans get the information and care they need to achieve their reproductive goals, whether that includes optimizing their health before desired…
- Conditions
- Contraception, Contraception Behavior, Prepregnancy Health, Reproductive Health
- Trial name
- MyPath (NCT04584294)
- Testing
- MyPath Web-Based Informational and Decision Support Tool
- Where
- 12 sites in United States
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Quality of Life, Cancer
Evaluating Cancer Survivorship Care Models
The Evaluating Cancer Survivorship Care Models project is an innovative 3-year study that is collecting data to help understand how to best deliver follow-up care to cancer survivors.
- Trial name
- NCT02362750
- Testing
- Consultative Specialized Survivorship Clinic (CSSC), Longitudinal Specialized Survivorship Clinic (LSSC), Oncology Embedded Survivorship Clinic (OESC)
- Where
- United States
- Volunteers
- 991 people
- Sponsor
- George Washington University