Clinical trials: Patient-Reported Outcomes
Locoregional Recurrence, Breast Cancer
Postoperative Re-irradiaTion With and Without HYPERthermia, or Surgery Only: Toxicity, Quality of Life and Survival in Patients With Locoregional Recurrent Breast Cancer
In the Netherlands, breast cancer patients with locoregional recurrence (LRR) and intermediate- and high-risk factors are treated with surgery with or without postoperative re-irradiation with or without hyperthermia.
- Conditions
- Locoregional Recurrence, Breast Cancer, Re-irradiation, Hyperthermia
- Trial name
- RT-HYPE (NCT06452485)
- Testing
- No interventions, patient-reported outcomes (PROMs) and toxicity will be collected in both groups.
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Amsterdam UMC, location VUmc
Lung Cancer
Predicting Symptom Trajectories After Thoracoscopic Lung Cancer Surgery Using an Interpretable Machine Learning Model
Patients suffer from a variety of symptoms after thoracoscopic surgery. However, there is a lack of validated predictive tools to identify potentially high-risk patients.
- Trial name
- NCT06771947
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Guangdong Provincial People's Hospital
Edentulous
a 10-year Follow-up Study of a Randomized Clinical Trial
In this study, the investigators propose a 10-year follow up study of participants in a randomized clinical trial to compare the oral health-related quality of life (OHRQoL), as well as general and related satisfaction of…
- Trial name
- NCT02289443
- Testing
- complete denture
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Nihon University
Stress Urinary Incontinence, Pelvic Organ Prolapse
Return to Physical Activity After Retropublic Transvaginal Sling and Laparoscopic Sacrocolpopexy
Advice on how long to limit physical activity after pelvic floor surgery ranges from 2 to 12 weeks and rests mainly on local tradition rather than data.
- Trial name
- RETURN (NCT07913815)
- Testing
- Questionnaire and Physical Exam
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Public Healthcare Centre of the Ministry of Interior and Administration
Chronic Myeloid Leukemia
Patient Reported Outcomes in Chronic Myeloid Leukemia
Although the impact of disease and treatment related burden on health-related quality of life (HRQOL) in patients with solid tumours has been well studied, with several clinical trials that included HRQOL as an endpoint, the…
- Trial name
- NCT01252589
- Testing
- HRQOL questionnaire
- Where
- 14 sites in United States, Austria and 8 more
- Volunteers
- 480 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Hip Pain Chronic
Long-term Follow up of Patients With Longstanding Hip and Groin Pain
In this longitudinal cohort study including young to middle aged people with longstanding hip and groin pain (LHGP) referred to tertiary care, we will collect data of patient reported symptoms, function and quality of life three…
- Trial name
- Lund LHGP (NCT03490071)
- Where
- Sweden
- Volunteers
- 58 people
- Sponsor
- Lund University
Trigeminal Neuralgia
Defining Core Outcome Sets in Trigeminal Neuralgia
The aim of this study is to determine what patients with trigeminal neuralgia (TN), clinicians and researchers in the field, consider to be the most important outcomes to be expected after undergoing treatment for trigeminal…
- Trial name
- TRINCOS (NCT04272385)
- Testing
- Observational
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University College, London
Thyroid Diseases
Health-Related Quality of Life for Thyroid Patients
Background: Thyroid diseases are frequent. They include both metabolic changes and gland enlargement (goitre). Previous research and clinical suspicion indicate that the life quality of many patients is reduced despite successful…
- Trial name
- NCT00150033
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Odense University Hospital
Cancer
Electronic Symptom Follow-up of Cancer Patients
Use of ePROs in oncological care have resulted in improvement of QoL, decreased ER visits, and improvement of overall survival. Furthermore, ePRO follow-up resulted in better QoL, improved ECOG status and more active cancer…
- Trial name
- NCT04081558
- Testing
- Electronic patient reported outcomes tool
- Where
- 2 sites in Finland
- Volunteers
- 43 people
- Sponsor
- Oulu University Hospital
Alveolar Bone Loss in Mandible, Guided Bone Regeneration
Clinical and Patient-reported Outcomes of Guided Versus Freehand Harvesting Of Positioning of Autogenous Bone Shells
When people lose teeth or have gum disease, the jawbone can shrink over time. This shrinkage makes it difficult for dentists to place dental implants because implants need a strong and stable base of bone.
- Conditions
- Alveolar Bone Loss in Mandible, Guided Bone Regeneration, Dental Implant
- Trial name
- guided (NCT07381608)
- Testing
- Free hand shell technique, Guided shell technique
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shalash Dental education
Colon Cancer, Gastric Cancer
A Novel Patient Engagement Platform Among Patients With Gastrointestinal Malignancies
A randomized control trial to evaluate the feasibility of implementing a patient educational platform (PEP) for patients with gastrointestinal malignancies undergoing active chemotherapy treatment.
- Conditions
- Colon Cancer, Gastric Cancer, Pancreas Cancer, Rectal Cancer
- Trial name
- NCT04316078
- Testing
- patient engagement platform
- Where
- Israel
- Volunteers
- 126 people
- Sponsor
- Sheba Medical Center
Idiopathic Pulmonary Fibrosis
To Assess the Efficacy of the Investigational Products Compared to Placebo in Participants With IPF
A participant- and investigator-blinded, randomized, placebo-controlled, multicenter, platform study to investigate efficacy, safety, and tolerability of various single treatments in participants with idiopathic pulmonary fibrosis
- Trial name
- NCT05497284
- Testing
- LTP001, Standard of Care (SoC)
- Where
- 15 sites in United States, Argentina and 5 more
- Volunteers
- 46 people
- Sponsor
- Novartis Pharmaceuticals
Enhanced Recovery After Surgery
Self-reported Outcomes of Patients in ERAS Nursing
We aimed to evaluate the effect of ERAS nursing program on self-reported outcomes of patients undergoing minimally invasive lung cancer surgery, and compared the differences in length of hospital stay, complications, and…
- Trial name
- NCT05528484
- Testing
- ERAS nursing, non eras nursing
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University
Hepatectomy, Pain, Postoperative
Spinal Anesthesia For Enhanced Recovery After Liver Surgery
This project proposes to compare epidural versus spinal anesthesia in patients having liver resection surgery. The investigators hypothesize that spinal anesthesia will result in improved blood pressure control postoperatively…
- Conditions
- Hepatectomy, Pain, Postoperative, Liver Neoplasms
- Trial name
- SAFER-L (NCT03715517)
- Testing
- Continuous thoracic epidural analgesia, Spinal anesthesia with intrathecal morphine, Bupivacaine 0.75% in Dextrose Inj 8.25%
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- University of Manitoba
High-risk Non-muscle Invasive Bladder Cancer
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)
Researchers are looking for new ways to treat high-risk non muscle invasive bladder cancer (HR NMIBC). NMIBC is cancer in the tissue that lines the inside of the bladder but has not spread to the bladder muscle or outside of the…
- Trial name
- NCT03711032
- Testing
- Pembrolizumab, BCG
- Where
- 209 sites in United States, Australia and 28 more
- Volunteers
- 1,397 people
- Sponsor
- Merck Sharp & Dohme LLC
All Conditions of Integrative Medicine Clinic Patients
Registry for Integrative Medicine Interventions Effectiveness
This registry will perform prospective surveillance of participants attending collaborating Integrative Medicine clinic sites for clinical services.
- Trial name
- PRIMIER (NCT01754038)
- Where
- 14 sites in United States
- Volunteers
- 5,069 people, healthy volunteers welcome
- Sponsor
- BraveNet
Stroke
Patient Reported Outcomes in Stroke Care
The presented study is an explorative prospective study. First, it focusses on the longitudinal analysis of outcome quality in stroke treatment (12 months).
- Trial name
- EPOS (NCT03795948)
- Testing
- PROMs
- Where
- Germany
- Volunteers
- 975 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hip Fractures, Hip Hemiarthroplasty
Observational Study to Evaluate Long-Term Outcome in Hip Hemiarthroplasty
This PMCF study is designed to collect safety and efficacy data on hip hemiarthroplasty surgeries with Corin BiPolar-i shell and the Oceane+ or Meije Duo femoral stem up to 10 years.
- Conditions
- Hip Fractures, Hip Hemiarthroplasty, Osteoarthritis, Hip, Avascular Necrosis of Hip
- Trial name
- NCT05686278
- Testing
- Bipolar i and cemented stem (Océane+ or Meije)
- Where
- 4 sites in France
- Volunteers
- 368 people
- Sponsor
- Corin
Hemophilia
Canadian CHO-KLAT/H-FIT Study - Quality of Life of, and Burden of Caring for, Persons With Hemophilia
The primary goal of this observational study is to determine if: health-related quality of life of boys with moderate/severe hemophilia A who are followed in Canadian pediatric hemophilia treatment centres is significantly…
- Trial name
- NCT06191068
- Where
- Canada
- Volunteers
- 190 people
- Sponsor
- The Hospital for Sick Children
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