Clinical trials: Patient-Reported Outcomes
Multiple Sclerosis
Acupressure in MS Patients
This study aims to evaluate the effects of acupressure therapy on patients with Multiple Sclerosis (MS). MS is a chronic autoimmune disease affecting the central nervous system, characterized by inflammation, demyelination, and…
- Trial name
- APEX-MS (NCT06755463)
- Testing
- Self-acupressure education
- Volunteers
- 82 people
- Sponsor
- Abant Izzet Baysal University
Knee Arthroplasty, Total, Telerehabilitation
Action Observation Therapy Via Telerehabilitation on Total Knee Arthroplasty Surgery
The goal of this clinical trial is to compare patient-reported and performance-based outcomes of patients followed with a standard exercise program based on telerehabilitation and patients followed with action observation therapy…
- Trial name
- NCT06162208
- Testing
- Standard exercise program based on telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Pamukkale University
Dental Caries, Primary Teeth
Non-Restorative Versus Conventional Caries Treatment in Primary Teeth: A Randomized Controlled Trial
Dental caries is common in young children, and treatment of cavities in primary teeth can be challenging. Conventional treatment usually involves removal of carious tooth tissue and placement of a restoration.
- Trial name
- NRCT (NCT07866755)
- Testing
- Non-restorative caries treatment (NRCT), CT
- Where
- Slovenia
- Volunteers
- 96 people
- Sponsor
- Lenka Likar Ostrc, DMD
Breast Cancer, Colon Cancer
Testing a Spanish Version of a Patient Toxicity Questionnaire
Background: The Common Terminology Criteria for Adverse Events (CTCAE) is a list of toxicities and side effects that may occur when people are having cancer treatment.
- Conditions
- Breast Cancer, Colon Cancer, Lung Cancer, Lymphoma
- Trial name
- NCT01517152
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- National Cancer Institute (NCI)
Inflammatory Bowel Disease (IBD)
Translating Scientific Evidence Into Practice Using Digital Medicine and Electronic Patient Reported Outcomes
Delivery of healthcare has been traditionally limited to in-person visits or hospitalizations, while patients spend the majority of their time at home or work. Digital Medicine (e.g.
- Trial name
- NCT04345393
- Testing
- Digital Transformation Network (DTN) Program
- Where
- 4 sites in United States
- Volunteers
- 659 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Obstructive Pulmonary Disease
REported Outcomes in COPD With Trixeo in Real worlD in Germany
Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms (including breathlessness, cough, and sputum production), which has a substantial impact on health-related quality of life (HRQoL).
- Trial name
- RECORD (NCT05311306)
- Where
- 62 sites in Germany
- Volunteers
- 475 people
- Sponsor
- AstraZeneca
Thyroid Diseases
Health-Related Quality of Life for Thyroid Patients
Background: Thyroid diseases are frequent. They include both metabolic changes and gland enlargement (goitre). Previous research and clinical suspicion indicate that the life quality of many patients is reduced despite successful…
- Trial name
- NCT00150033
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Odense University Hospital
Acute Myeloid Leukemia (AML)
Feasibility Pilot Exploring Variability in Biomarkers and PROs in AML
This research study is being conducted to help understand how the symptoms during treatment for acute myeloid leukemia (AML) may be affected by metabolism and how best to study this association.
- Trial name
- NCT04908852
- Testing
- Blood Sample Collection - Observational Study, Symptom questionnaires - Observational Study
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
HIV/AIDS
The I-Score Study: Developing a New Patient-Reported Tool for the Routine HIV Care of Patients on Antiretroviral Therapy
The purpose of this Canada-France study is to develop and validate a multidimensional patient-reported measure of perceived barriers to antiretroviral therapy adherence for HIV-positive patients undergoing treatment that will be…
- Trial name
- NCT02586584
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Dr. Bertrand Lebouche
Gastrointestinal Cancer, Urologic Cancer
Palliative Radiotherapy in Symptomatic Pelvic Soft Tissue Tumors
PALLSOFT is a randomized, open-label, non-inferiority phase III, multicenter, national trial that will investigate whether the patient-reported symptomatic effect of palliative radiotherapy delivered in 1-2 fractions is…
- Conditions
- Gastrointestinal Cancer, Urologic Cancer, Gynecologic Cancer
- Trial name
- PALLSOFT (NCT06398314)
- Testing
- Palliative radiotherapy
- Where
- 11 sites in Norway
- Volunteers
- 200 people
- Sponsor
- Sykehuset Telemark
Extended Depth-of-Focus Intraocular Lens, Cataract
Visual and Patient-Reported Outcomes After Bilateral Non-Diffractive EDOF IOL Implantation
This study evaluates visual outcomes and patient-reported satisfaction following bilateral cataract surgery using a non-diffractive extended depth-of-focus (EDOF) intraocular lens (AcrySof IQ Vivity).
- Conditions
- Extended Depth-of-Focus Intraocular Lens, Cataract, Visual Acuity
- Trial name
- EDOF-Visual (NCT07457216)
- Testing
- AcrySof IQ Vivity EDOF Intraocular Lens
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
HIV/AIDS and Infections, Patient Preference
Patient-Reported Outcomes HIV BItherapy
HIV Treatment simplification strategies that involve switching cART regimens from four or three antiretrovirals to two in virologically suppressed patients living with HIV are now available in order to reduce long-term toxicity…
- Trial name
- PROBI (NCT04788784)
- Where
- 3 sites in France
- Volunteers
- 250 people
- Sponsor
- University Paris 7 - Denis Diderot
Kidney Maintenance Transplant
Measurement of Patient Reported Outcomes in Renal Transplant Patients With and Without Gastrointestinal (GI) Symptoms (PROGIS)
The purpose of this study is to assess the impact that GI complaints have on patient reported outcomes in renal transplant recipients and to determine if there is improvement in patient reported outcomes when patients are…
- Trial name
- NCT00150007
- Testing
- Enteric-coated Mycophenolate sodium (EC-MPS)
- Volunteers
- 335 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure, Coronary Artery Disease
The Helios Heart Registry: A Standardized Registry for Patients With Specific Cardiac Diseases
Investigator-initiated, prospective, non-randomized, open label, non-interventional multicenter registry to evaluate current treatment of three major cardiovascular disease entities in clinical practice using a standardized…
- Conditions
- Heart Failure, Coronary Artery Disease, Atrial Fibrillation
- Trial name
- H²-Registry (NCT04844944)
- Where
- 10 sites in Germany
- Volunteers
- 24,000 people
- Sponsor
- Helios Health Institute GmbH
Metastatic Renal Cell Carcinoma, Kidney Neoplasm
Individualized Treatment Strategy for Patients With Metastatic Non-clear Cell Renal Cell Carcinoma
The purpose of the open-label INDIGO-study is to examine whether a first line individualized treatment strategy based on DNA and RNA analyses from the patient's tumor is feasible.
- Conditions
- Metastatic Renal Cell Carcinoma, Kidney Neoplasm, Urologic Neoplasms, Urogenital Neoplasms
- Trial name
- INDIGO (NCT04644432)
- Testing
- Medication (A specification is listed under each arm), Patient reported outcomes measurement
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Herlev and Gentofte Hospital
Postpartum Complication
Healing, Equity, Advocacy and Respect for Mamas
The goal of the proposed research is to test the comparative effectiveness of AIM safety bundles for post-partum women delivered in-person vs.
- Trial name
- HEAR4Mamas (NCT06273436)
- Testing
- H.E.A.R. for Mamas
- Where
- United States
- Volunteers
- 2,894 people
- Sponsor
- Medical University of South Carolina
Neuropathic Pain
The Effect of Central Sensitization and Neuropathic Pain After Total Knee Arthroplasty
It has been well known that central sensitization (CS) is a risk factor for inferior outcomes following total knee arthroplasty (TKA).
- Trial name
- NCT05581836
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- The Catholic University of Korea
Rosacea, Erythema
Patient-Reported Outcome Of Facial Erythema (PROOF)
The purpose of the study is to evaluate the patient-reported outcomes (feedbacks of patients)of a new drug for the treatment of erythema of rosacea (central facial redness).
- Trial name
- PROOF (NCT01885000)
- Testing
- Brimonidine tartrate was applied cutaneously once daily for 8 days., Brimonidine tartrate vehicle was applied cutaneously once daily for 8 days.
- Where
- 14 sites in Germany, Sweden and 1 more
- Volunteers
- 92 people
- Sponsor
- Galderma R&D
Pleural Effusion, Dyspnea
Thoracentesis: Symptoms and Prediction of the Need for Therapeutic Thoracentesis
Recurrent fluid surrounding the lungs is associated with poor quality of life, the main symptom being dyspnea. These patients are in need of recurrent removal of the fluid using drainage.
- Conditions
- Pleural Effusion, Dyspnea, Patient Reported Outcomes, Diaphragm Movement
- Trial name
- NCT04236934
- Testing
- Assesment of diaphragm shape and diaphragm movement (by M-mode and the AREA-method) by ultrasound before and after thoracentesis
- Where
- 2 sites in Denmark
- Volunteers
- 107 people
- Sponsor
- Naestved Hospital
Hepatitis C, Chronic
Real World Study: Genotype 1 Chronic Hepatitis C Virus Treatment and Evaluation of Real World SVR and PRO
This is a Phase IV, open-label, multi-center study to evaluate the real world sustained virological response rate, subject adherence, and subject reported outcomes during and after treatment of non-cirrhotic genotype 1 chronic…
- Trial name
- NCT02461745
- Testing
- ombitasvir, paritaprevir/r, dasabuvir + ribavirin, ombitasvir, paritaprevir/r, dasabuvir
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Kaiser Permanente
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