Clinical trials: Patients Died in Intensive Care Unit (ICU)
Pregnancy, Postpartum
Organ Dysfunction Score for Obstetric Patients
The goal of this observational study is to develop and evaluate an organ dysfunction score adapted to pregnancy and early puerperium (SOFA-OBS) that also incorporates a non-invasive tool to evaluate respiratory function (pulse…
- Conditions
- Pregnancy, Postpartum, Organ Dysfunction, Critical Care, Intensive Care
- Trial name
- SOFA-OBS (NCT07068022)
- Testing
- Organ dysfunction score adjusted to obstetric patients (SOFA-OBS)
- Where
- 18 sites in Argentina, Ecuador and 2 more
- Volunteers
- 130 people
- Sponsor
- Daniela Vasquez
Sepsis, ARDS
Microcirculation and Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit
As medicine advances, many lives can be saved in the intensive care unit. However, when multiple organ failure occurs, the mortality rate of patients increases dramatically.
- Conditions
- Sepsis, ARDS, Liver Failure, Renal Failure
- Trial name
- NCT00808691
- Testing
- Critical care
- Where
- Taiwan
- Volunteers
- 124 people
- Sponsor
- National Taiwan University Hospital
Brain Injury, Coma
Brain Death and Organ Donation in Tunisian Intensive Care Units
The goal of this observational study was to identify factors associated with the progression to brain death in critically ill patients with severe brain injuries in Tunisian intensive care units (ICUs).
- Conditions
- Brain Injury, Coma, Organ Transplants
- Trial name
- BDOD-TN (NCT06948669)
- Where
- Tunisia
- Volunteers
- 104 people
- Sponsor
- Faculty of Medicine, Sousse
Sepsis
Safety of Heparin in Patients With Septic Shock
Sepsis is a syndrome comprised of a systemic inflammatory response, signs of tissue hypoperfusion, and organ in the setting of presumed infection.
- Trial name
- NCT01234285
- Testing
- heparin
- Where
- United States
- Sponsor
- University of Colorado, Denver
Diarrhea, Death
Lactobacillus Preparation on the Incidence of Diarrhea
The purpose of this trial is to clarify the impact of lactobacillus preparation on the incidence of diarrhea in ICU-admitted patients.
- Conditions
- Diarrhea, Death, Pneumonia
- Trial name
- NCT01792739
- Testing
- Lactobacillus casei variety rhamnosus granules
- Where
- 3 sites in South Korea
- Volunteers
- 124 people
- Sponsor
- Seoul National University Hospital
Burden, Dependency, Mortality
Burden, Mortality and Supply Costs in Intensive Care Unit Patients
This study systematically observes in a pragmatic trail under real world conditions the association between strategies of therapy (maximal therapy, withhold, withdraw) and treatment success in three endpoint related initial risk…
- Conditions
- Burden, Dependency, Mortality, End-of-life Care, Intensive Care Unit
- Trial name
- PLV_Ulm (NCT04094428)
- Where
- Germany
- Volunteers
- 700 people
- Sponsor
- University of Ulm
Family of Dying Patient in the ICU
A Communication Strategy for Families of Patients Dying in the ICU
Decisions to limit life sustaining treatments are made for most patients dying in the ICU, usually with input from the family. The well-being of the family may be jeopardized by involvement in the decision-making process and…
- Trial name
- NCT00331877
- Testing
- family conference with bereavement information leaflet
- Volunteers
- 136 people
- Sponsor
- Famirea Study Group
Physiological Dead Space, Ventilation-Perfusion Mismatch
Correlation of EtCO₂- and P(A-a)O₂-Based Dead Space Calculations in Mechanically Ventilated ICU Patients
This study aims to evaluate two different methods for calculating physiological dead space in adult patients undergoing invasive mechanical ventilation in the intensive care unit (ICU).
- Conditions
- Physiological Dead Space, Ventilation-Perfusion Mismatch, Mechanical Ventilation, Enghoff Correction
- Trial name
- CODE-EtA (NCT06947486)
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Karadeniz Technical University
Osteoarticular Infections, Intensive Care Patients
Prosthetic Joint Infection : Lessons From Deceased Patients in Critical Care.
This is an observational, retrospective, multicenter study based on the use of demographic, clinical and biological data from deceased patients admitted between 2018 and 2022 to critical care with a principal or associated…
- Conditions
- Osteoarticular Infections, Intensive Care Patients, Prosthetic Joint Infection
- Trial name
- OASIS² (NCT07107685)
- Testing
- Global cohort
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression, Depressive Symptoms
ICU Family Communication Study
The purpose of this study is to improve care in the Intensive Care Unit (ICU) by focusing on communication with family members of patients who are too sick to make decisions about their own care while they are in the ICU.
- Conditions
- Depression, Depressive Symptoms, Anxiety, Stress Disorders, Post-Traumatic
- Trial name
- NCT00720200
- Testing
- Facilitator-Based intervention, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 593 people
- Sponsor
- University of Washington
Respiratory Complications, Pneumonia
Incidence and Complications of Post-extubation and Post-tracheostomy Dysphagia in Adult Patients in the Critical Care Unit
Acquired Swallowing Disorder in ICU (ICU-ASD), also known as postextubation dysphagia, is a multicausal problem experienced by survivors in intensive care units (ICUs) when the efficiency, safety of swallowing, or both are…
- Conditions
- Respiratory Complications, Pneumonia, Quality of Lifte, Death
- Trial name
- NCT06583824
- Volunteers
- 414 people
- Sponsor
- Complejo Hospitalario Universitario de Albacete
Intensive Care Unit Stay, Death
Team Elements Associated With Mortality in Intensive Care
The individual characteristics and interactions of health care workers in intensive care units may influence patient safety. This study aims to quantify the influence of team familiarity among the members of medical and nursing…
- Trial name
- TEAMIC (NCT03162146)
- Testing
- Deaths in intensive care unit
- Where
- France
- Volunteers
- 43,378 people
- Sponsor
- Hospices Civils de Lyon
Palliative Care
Proactive Palliative Care Intervention in a Surgical ICU: Influence on Family Satisfaction and Patient Distress
Patients will be identified according to pre-defined trigger criteria for a palliative intervention. One hundred patients of a control group will receive standard intensive care treatment (Usual Care Group).
- Trial name
- PALL-ICU (NCT03287323)
- Testing
- Proactive Palliative Care
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Johannes Gutenberg University Mainz
Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder)
Evaluation of the Patient Deterioration Warning System
The overall goal of the project is to reduce the number of unexpected patient deteriorations by 50% at Emergency Departments (ED) by investigating if the novel Patient Deterioration Warning Systems (PDWS), can improve clinicians'…
- Conditions
- Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder), Cardiac Arrest (Disorder), Patient Died in Hospital (Finding)
- Trial name
- PDWS (NCT03375658)
- Testing
- PDWS Intervension
- Where
- 2 sites in Denmark
- Volunteers
- 6,500 people
- Sponsor
- University of Southern Denmark
Ventilator Associated Pneumonia, Death
Futility of Exhaled Breath Condensate pH Measurements in Ventilated Patients in Intensive Care Unit (ICU)
Measurement of pH in Exhaled breath condensate has been mentioned as a robust variable from lung inflammation. It is non-invasive and reproducible.
- Trial name
- NCT01393431
- Where
- Argentina
- Volunteers
- 34 people
- Sponsor
- Universidad Nacional de Rosario
SARS-CoV-2, Covid19
Pathological Findings of Fatal COVID-19
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new coronavirus discovered in December 2019 in Wuhan, China and currently responsible of a worldwide outbreak and the death of more than 55,000 patients in…
- Conditions
- SARS-CoV-2, Covid19, Pathology, Intensive Care Units
- Trial name
- HISTOCOVID (NCT04675281)
- Testing
- 2 post-mortem transcutaneous lung biopsies (1 anterior ; 1 posterior) using anatomical landmarks
- Where
- 44 sites in France
- Volunteers
- 170 people
- Sponsor
- Nantes University Hospital
Acute Kidney Failure, Renal Replacement Therapy for Acute Kidney Injury in ICU
Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)
The STEPCARE-MAKE study is a predefined sub-study of the large Sedation, TEmperature and Pressure after Cardiac Arrest and REsuscitation (STEPCARE) trial, which evaluates the effects of three interventions in comatose adult…
- Conditions
- Acute Kidney Failure, Renal Replacement Therapy for Acute Kidney Injury in ICU, Sedation in Intensive Care Unit Patients, Sedation in the ICU
- Trial name
- STEPCARE-MAKE (NCT07579390)
- Testing
- Feedback-controlled temperature device, High MAP, Deep sedation
- Where
- 52 sites in Australia, Belgium and 12 more
- Volunteers
- 3,500 people
- Sponsor
- Helsinki University Central Hospital
Invasive Mechanical Ventilation, Ventilation-Perfusion Mismatch
Physiological Dead Space and Intensive Care Mortality in Mechanically Ventilated Patients
This study investigates the relationship between physiological dead space and clinical outcomes, specifically mortality and discharge status, in adult patients receiving invasive mechanical ventilation in the intensive care unit…
- Conditions
- Invasive Mechanical Ventilation, Ventilation-Perfusion Mismatch, ICU Mortality, Critical Illness
- Trial name
- IRIS-MAP (NCT06963944)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Karadeniz Technical University
Terminal Illness, Intensive Care Unit Syndrome
End Of Life in the Critically Ill patiEnt
The purpose of this multicentric study is to evaluate the perception of the quality of the end of life in intensive care units seen from the side of the caregivers, trough the CAESAR scale.
- Trial name
- EOLE (NCT03392857)
- Testing
- Assessment by caregivers of the quality of the end of life in intensive care units
- Where
- 112 sites in France
- Volunteers
- 514 people
- Sponsor
- French Society for Intensive Care
Shock, Death
Polish Nationwide Register of Hospitalized Patients in Cardiac Intensive Care Units
Cardiac Intensive Care Units (CICUs) provide care for a diverse patient population. Understanding the clinical characteristics, analysis of treatment modalities, and prognosis of patients hospitalized in the CICU are important to…
- Conditions
- Shock, Death, Cardiac Intensive Care Unit, Treatment Complication
- Trial name
- POL-CICU (NCT06371677)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw