Clinical trials: Patients Undergoing Elective Craniotomy
Patients Undergoing Elective Craniotomy
Efficacy of Adding Low Dose Ketamine or Fentanyl to Propofol-dexmedetomidine as Total Intravenous Anesthesia
Efficacy of adding low dose ketamine or fentanyl to propofol-dexmedetomidine as total intravenous anesthesia for patients undergoing craniotomy in supra tentorial brain tumor
- Trial name
- TIVA (NCT06031883)
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Skull Pin Insertion
The Lowest Effective Dose of Dexmedetomidine in Attenuating the Hemodynamic Responses During Skull Pin Insertion in Patients Undergoing Elective Craniotomy
Skull pins are used to immobilize the head during craniotomy. Fixation of skull pins causes acute hemodynamic changes which may affect cerebral autoregulation and hence cerebral blood flow.
- Trial name
- NCT03738059
- Testing
- Dexmedetomidine Injection [Precedex], normal saline 0.9%
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Craniotomy
Scalp Block in Elective Craniotomy for Tumor Dissection Trial
This study was designed to evaluate the effect of scalp block combined with general anesthesia on the intraoperative consumption of fentanyl and time of extubation of patients undergoing elective craniotomy.
- Trial name
- NCT03776617
- Testing
- scalp block
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- George Papanicolaou Hospital
Stress
Effects of TEAS on Stress Response During Extubation of General Anesthesia in Elderly Patients
Elderly patients have an increased risk of stress responses during extubation after general anaesthesia for an elective supratentorial craniotomy.
- Trial name
- NCT02533388
- Testing
- Hwato Electronic Acupuncture Treatment Instrument
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Brain Edema Caused by Drugs, Cerebral Oxygenation
Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive Outcome
The brain is a metabolic active organ with constant energy demands. Brain oxygen supply is secured via cerebral circulation. Brain tumor surgery is commonly associated with the tumor's underlying pathophysiology including brain…
- Trial name
- TIVolBrain (NCT06779890)
- Testing
- Sevoflurane, Desflurane
- Where
- 2 sites in Greece
- Volunteers
- 84 people
- Sponsor
- Georgia Tsaousi
Brain Tumor
Influences of Propofol and Sevoflurane Anesthesia in Brain Tumor
In the preoperative waiting area, the patients are randomly assigned and divided into two groups according to the allocation sequence table (corresponding to 1:1 randomization) generated by the computer.
- Trial name
- anesthetics (NCT05141877)
- Testing
- Propofol, Sevoflurane
- Where
- Taiwan
- Volunteers
- 706 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Aneurysm Cerebral
Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy
This study is looking at how taking aspirin regularly affects bleeding during and after brain surgery. Specifically, it focuses on patients who are having elective surgery to clip a brain aneurysm.
- Trial name
- ASPRIN (NCT07086183)
- Testing
- Observation
- Where
- 3 sites in United States, Italy and 1 more
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Patients Undergoing Elective Craniotomy
Conversion From Total Intravenous Anesthesia Technique to Desflurane Anesthesia for Long Duration Neurosurgery
Since neurological testing during neurosurgery, such as somato-sensory evoked potentials, motor-evoked potentials, auditory evoked potentials and visual evoked potentials are well maintained their wave-form reactivity with total…
- Trial name
- NCT01985854
- Testing
- Propofol, Desflurane
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Tokyo Women's Medical University
Adult Brain Tumor
Light Sedation or Intubated General Anesthesia in Patients With Brain Cancer Undergoing Craniotomy
This randomized clinical trial studies light sedation compared with intubated general anesthesia (a loss of feeling and a complete loss of awareness that feels like a very deep sleep) in reducing complications and length of…
- Trial name
- NCT02193568
- Testing
- Arm I (light sedation), Arm II (intubated general anesthesia)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Supratentorial Brain Tumor
Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy
Introduction: Scalp incision is a powerful nociceptive stimulus that can exacerbate rapid changes in hemodynamic and sympathetic activity.
- Trial name
- NCT05763836
- Testing
- Ibuprofen 800 Mg in 8 mL INTRAVENOUS INJECTION [Caldolor], Scalp nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ankara University
Brain Tumour
Scalp Nerve Block and Opioid Consumption in Brain Surgery
Anterior scalp block with 0.5% plain Marcaine 20 ml. may reduce the intraoperative opioid consumption in neurosurgical patients who undergoing the supratentorial craniotomy compared to those who receive 0.9% normal saline…
- Trial name
- NCT02057367
- Testing
- Scalp block with 0.5% plain Marcaine, Scalp block with 0.9% normal saline
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Regional Cerebral Oxygen Saturation
Effect of Different Positive End Expiratory Pressures on Regional Cerebral Oxygen Saturation
The goal of this prospective single-blind randomized clinical trial is to compare the effect of two different positive end expiratory pressure (PEEP) levels on regional cerebral oxygen saturation in patients scheduled for…
- Trial name
- NCT05961917
- Testing
- 5 cmH2O Positive end-expiratory pressure (PEEP), 10 cmH2O Positive end-expiratory pressure (PEEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bozyaka Training and Research Hospital