Clinical trials: Patients Undergoing General Anesthesia
Supraglottic Airway Device
A Comparison of the I-gel and Self-pressurised Air-Q Intubating Laryngeal Airway (Air-Q sp) in the Elderly Patients
Supraglottic airway devices (SADs) are well established in anesthetic practice. Among these devices, the i-gel has been typically widely used.
- Trial name
- NCT02260427
- Testing
- Insertion of the i-gel, Insertion of the air-Q sp
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Hypovolemia
Fluid Responsiveness Using Forehead Sensor in Children
Forehead sensor can predict the more accurate fluid responsiveness than finger sensor in children
- Trial name
- forehead (NCT03132480)
- Testing
- fluid resuscitation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Neurocognitive Disorders, HbA1c
HbA1c and Neurocognitive Disorders
Preliminary evidence suggest a possible relationship between HbA1c and perioperative neurocognitive disorders (NCD). We are going to investigate whether the preoperative value of HbA1c in patients undergoing elective non-cardiac…
- Trial name
- NCT04736277
- Testing
- Preoperative HbA1c
- Where
- Greece
- Volunteers
- 288 people
- Sponsor
- University of Thessaly
Postoperative Nausea and Vomiting
Drug and Dose Adjustment in Preventing Postoperative Nausea and Vomiting
The aim is to evaluate the effectiveness of different regimens of prophylactic Ondansetron, Dexamethasone, or both, on the incidence and severity of post-operative nausea and vomiting.
- Trial name
- NCT04719741
- Testing
- Parallel Assignment
- Where
- Jordan
- Volunteers
- 1,000 people
- Sponsor
- Jordan Hospital
Airway Management, Respiration, Artificial
Non-inferiority Trial Between Sotair® Device Attached to Manual Resuscitator Versus Mechanical Ventilation
Effective respiratory ventilation is achieved by moving the right amount of air in and out of the lungs while keeping the pressures at a safe level.
- Trial name
- NCT06117683
- Testing
- ADULT Sotair Device
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- Rhode Island Hospital
Perioperative Anxiety, Postoperative Pain
Perioperative Effect of Music in Patients Undergoing General Anesthesia
Anxiety is a transient emotional state characterized by feelings of tension, apprehension, nervousness, fear, and heightened activation of the autonomic nervous system in response to a specific current or potential event or…
- Trial name
- EMBAG (NCT05572437)
- Testing
- Music Therapy
- Where
- Spain
- Volunteers
- 151 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Postoperative Delirium, Hemodynamic Instability
Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies
In the PATHFINDER 2 trial, the study investigators will test the intraoperative EEG-guided multimodal general anesthesia (MMGA) management strategy in combination with a postoperative protocolized analgesic approach to: 1.
- Conditions
- Postoperative Delirium, Hemodynamic Instability, Pain, Neurocognitive Dysfunction
- Trial name
- PATHFINDERII (NCT05279898)
- Testing
- EEG Monitoring, Ropivacaine, Ketamine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Pain, Abdominal Surgery by Laparotomy
Rectus Sheath Block as an Adjunct to General Anesthesia for Midline Laparotomy Pain
This study evaluates whether adding an ultrasound-guided rectus sheath block (RSB) to general anesthesia can improve pain control after midline laparotomy.
- Trial name
- RSB-MIDLINE (NCT07393763)
- Testing
- Ultrasound-guided rectus sheath block
- Where
- Indonesia
- Volunteers
- 46 people
- Sponsor
- Udayana University
General Anesthesia Versus Spinal Anesthesia on BNP Hormone Levels Preoperatively and Postoperatively in Parturient Cardiac Patient Undergoing C.S
Effect of Different Types of Anesthesia on Perioperative Brain Natriuretic Peptide Levels in Parturient Cardiac Patient Undergoing Elective Cesarean Section
comparing the effect of general anesthesia versus spinal anesthesia on brain natruretic peptide hormone levels preoperatively and postoperatively in parturient cardiac patient undergoing cesarean section
- Trial name
- NCT03460184
- Testing
- G.A Group A:
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia
Study of the Efficacy and Safety of Remimazolam in General Anesthesia in Adults Undergoing Cardiac Surgery
This study investigates the use of remimazolam as a sedative/hypnotic in general anesthesia. Remimazolam or propofol will be administered together with fentanyl/sufentanil/remifentanil as opioid analgesics and a neuromuscular…
- Trial name
- NCT02523859
- Testing
- Propofol, Remimazolam
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Paion UK Ltd.
Anesthesia, Asthma
Effect of Dexmedetomidine on Levels of Plasma Inflammatory Factor in Asthma Patients Undergoing General Anesthesia
The study try to illustrate the possible mechanisms of tending to induce airway spasms and the impact of dexmedetomidine on inflammatory reaction in general anesthesia patients with asthma，by detecting the differences of plasma…
- Trial name
- NCT02289391
- Testing
- Anesthesia induction, Anesthesia maintenance, Assisted anesthesia
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
General Anesthesia, Elective Laparoscopic Cholecystectomy
The Effect of Positive End-Expiratory Pressure Levels on Perfusion Index and Neurocognitive Functions in Geriatric Patients
With the increasing geriatric population, age-related physiological changes and common comorbidities increase the risk of surgical and anesthesia-related complications in this patient group.
- Trial name
- NCT07505550
- Testing
- PEEP levels
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Ankara City Hospital Bilkent
Prostate Tumor
Remimazolam Versus Propofol for General Anesthesia Induction in Patients on Renin-angiotensin System Blockers Undergoing Robot-assisted Laparoscopic Prostatectomy
The investigators conduct a random assignment into either the remimazolam group or the propofol group. Depending on the group assignment, either remimazolam (0.2 mg/kg) or propofol (1.0 mg/kg) is administered.
- Trial name
- NCT06093971
- Testing
- remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Yonsei University
Asana Adjustment
Effects of Postural Adjustment on Hemodynamics in Patients Undergoing Prone Spine Surgery Under General Anesthesia
The prone position is a special position often used for spinal surgery. As a special position of general anesthesia, after induction of general anesthesia, severe hemodynamic fluctuations often occur when the supine position is…
- Trial name
- NCT05749978
- Testing
- Asana adjustment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhuan Zhang
Breast Cancer
Comparison of Paravertebral Block With General Anesthesia in Patients Undergoing Breast Cancer Surgery
The purpose of this project is to determine if there is a difference between paravertebral block and general anesthesia in terms of time to discharge from the Post-Anesthesia Care Unit and pain level in patients undergoing…
- Trial name
- NCT00645138
- Testing
- Paravertebral Block, General Anesthesia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University
Temperament, Trauma (Including Fractures)
How Personality Type Affects Pain and the Need for General Anesthesia in Patients Receiving an Arm Nerve Block for Wrist Fracture Surgery
This study looked at whether a person's emotional personality type affects how they experience pain and how well a regional anesthesia technique works during arm surgery.
- Trial name
- NCT07450768
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Anesthesia
High Flow Oxygen in Patients Undergoing Surgery Under General Anesthesia
Preoxygenation remains an important determinant of morbidity and mortality in anesthesia despite advances in mask ventilation and difficult intubation management. 1.
- Trial name
- OPTIFLOW (NCT03554863)
- Testing
- Nasal High Flow Oxygen, Facial Mask
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- CMC Ambroise Paré
Anesthesia, General, Anesthesia, Spinal
The Effect of General and Spinal Anesthesia on Neutrophil-to-lymphocyte Ratio
The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV)…
- Conditions
- Anesthesia, General, Anesthesia, Spinal, Umbilical Cord
- Trial name
- NCT05409885
- Testing
- General anesthesia, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Hypotension
Efficacy of Dexamethasone in Attenuation of Postinduction Hypotension in Geriatric Patients Undergoing General Anesthesia
Geriatric patients who undergo general anesthesia experience post induction hypotension which is treated with intravenous fluids and ephedrine.
- Trial name
- NCT04908592
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Ultrasound Guided L1,L2 Paravertebral Block
Effect of Ultrasound Guided L1,L2 Paravertebral Block in Decrease the Requirements for Hypotensive Drugs During General Anesthesia in Patients Undergoing Hip Surgeries.
The paravertebral block (PVB) is a block of the mixed nerve soon after it exits the intervertebral foramen.(2) It provides intense unilateral analgesia of long duration and has become the primary anesthetic for many…
- Trial name
- NCT03422354
- Testing
- Ultrasound guided PVB with General Aneasthesia, Ultrasound, Paravertebral block
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cairo University