Clinical trials: Patients Undergoing Invasive Cardiac Procedures
Cardiovascular Complications, Hemorrhagic Complications
Prospective Cohort of Patient With Coronary Stents Undergoing Non Cardiac Surgery
Non cardiac surgery in patients with coronary stents is complicated with cardiovascular and hemorrhagic events associated with perioperative management of antiplatelet agents.
- Trial name
- RECO (NCT01045850)
- Where
- 53 sites in France
- Volunteers
- 1,312 people
- Sponsor
- University Hospital, Grenoble
Angina (Stable), Percutaneous Coronary Intervention (PCI)
Advanced Invasive Diagnosis Strategy for Post-PCI Patients With Stable Coronary Syndromes Undergoing Coronary Angiography
AID Post-PCI Angina is as an observational, prospective, single-cohort, multicenter study designed to investigate the causes and origins of post-PCI angina by using the advance invasive diagnosis (AID) strategy combining with…
- Conditions
- Angina (Stable), Percutaneous Coronary Intervention (PCI), INOCA (Ischemia With Non Obstructive Coronary Artery Disease), Chronic Coronary Syndrome
- Trial name
- NCT07638137
- Testing
- An advanced invasive diagnosis (AID) strategy combining with angiography derived physiology (ADP)
- Where
- 5 sites in Spain
- Volunteers
- 246 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
Atrial Flutter
Cardiac Electrophysiological Study
The purpose of the study is to measure the effects of AZD1305 on cardiac electrophysiological properties and intracardiac pressures
- Trial name
- NCT00616629
- Testing
- AZD1305
- Where
- 13 sites in Denmark, Finland and 2 more
- Volunteers
- 55 people
- Sponsor
- AstraZeneca
Patients Undergoing Invasive Cardiac Procedures, Radiation Exposure
Reducing Radiation Exposure to Operators During Invasive Cardiac Procedures
The primary objective of this study is to determine if a novel lead-based arm board is effective at reducing radiation dose to the operator during invasive cardiac procedures.
- Trial name
- RADAR (NCT03605030)
- Testing
- Novel Lead Based Armboard, Standard Armboard
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- London Health Sciences Centre
Genetic Polymorphism
The Role of Platelet Surface α2β1 Integrin Expression as a Risk Factor in Thrombotic and/or Bleeding Complications
This study will begin to define these critical determinants for patients undergoing procedures in the hybrid interventional cardiology/cardiac surgery suite.
- Trial name
- NCT00603148
- Where
- United States
- Volunteers
- 475 people
- Sponsor
- Vanderbilt University
Heart Failure With Severe Tricuspid Regurgitation
TRICuspid Intervention and Invasive Hemodynamic Monitoring in Heart Failure
Tricuspid regurgitation (TR) is a severe and highly prevalent disease that leads to right-sided heart failure. The severity of TR is associated with increasing morbidity and mortality.
- Trial name
- TRIC-I-HF 2 (NCT07442903)
- Testing
- Pulmonary artery sensor system
- Where
- 2 sites in Germany
- Volunteers
- 45 people
- Sponsor
- LMU Klinikum
Thrombosis, Cancer
Safety of Perioperative Anticoagulation Management in People With Active Cancer Undergoing Cancer-Related Surgery or Procedures (ACE-HIGH Study)
The purpose of this study is to help find how safe current practices are when managing blood thinners in people with cancer who are having surgery or medical procedures.
- Conditions
- Thrombosis, Cancer, Thrombosis, Deep Vein, Atrial Fibrillation (AF)
- Trial name
- ACE-HIGH (NCT07372716)
- Testing
- standardized perioperative anticoagulation management Guideline
- Where
- Canada
- Volunteers
- 700 people
- Sponsor
- Ottawa Hospital Research Institute
Anxiety State, Invasive Procedure
Effect of Information Given and Music on the Care of Patient Who Will Undergo Coronary Angiography
Today, due to the increasing frequency of cardiovascular diseases the number of coronary angiography performed has also risen. This invasive procedure has an effect on patients which causes anxiety.
- Trial name
- NCT04276506
- Testing
- music group, information group
- Where
- Cyprus
- Volunteers
- 184 people
- Sponsor
- Eastern Mediterranean University
Intraoperative Hypotension, Acute Kidney Injury
Non-invasive Measurement of the Hypotension Prediction Index for the Reduction of Intraoperative Hypotension
In order to reduce the incidence of IOH, various goal-directed therapy (GDT) protocols have already been introduced with success regarding the reduction of postoperative AKI and MINS.
- Conditions
- Intraoperative Hypotension, Acute Kidney Injury, Myocardial Injury After Non-cardiac Surgery
- Trial name
- Clearsight (NCT06291714)
- Testing
- GDT-based hemodynamic management based on Clearsight device
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University of Giessen
Cardiac Surgical Procedure
Postoperative Patency of Internal Jugular Vein After Neck Cannula Insertion
The number of patients undergoing Minimally Invasive Cardiac Surgery (MICS) is increasing each year. MICS procedures on atrioventricular valves are usually performed without conventional sternotomy, an alternative approach is…
- Trial name
- NCT02456259
- Testing
- Neck cannula insertion
- Where
- Czechia
- Volunteers
- 110 people
- Sponsor
- University Hospital Hradec Kralove
Angina Pectoris
Comparison of Loading Strategies With Antiplatelet Drugs in Patients Undergoing Elective Coronary Intervention
Use of high loading doses of clopidogrel (antiplatelet drug) just before coronary interventions is associated with improved outcomes after coronary stenting.
- Trial name
- SASSICAIA (NCT02548611)
- Testing
- Prasugrel, Clopidogrel
- Where
- 5 sites in Germany, Hungary
- Volunteers
- 795 people
- Sponsor
- LMU Klinikum
Atrial Fibrillation, Coronary Artery Disease
Comparison Between Direct Oral Anticoagulation (DOAC) Interruption and DOAC Continuation in Patients Undergoing Elective Invasive Coronary Angiography or Percutaneous Coronary Intervention
A prospective, multicenter, 1:1 randomized, investigator initiated study. Goal of this study is to examine the safety of uninterrupted periprocedural DOAC use.
- Conditions
- Atrial Fibrillation, Coronary Artery Disease, Anticoagulants
- Trial name
- SLIM-2 (NCT04977076)
- Testing
- Uninterrupted DOAC use, Interrupted DOAC use
- Where
- Netherlands
- Volunteers
- 1,270 people
- Sponsor
- Zuyderland Medisch Centrum
Bariatric Surgery, Hemodynamics
Non-invasive Assessment of Cardiac Output and Fluid Responsiveness in Bariatric Surgery
Comparability of discontinuous non-invasive (sphygomanometric) and continuous semi-invasive and invasive (Masimo©; Nexfin© Monitoring ; FloTrac © Edwards Lifesciences) beat to beat measurement methods for the determination of…
- Trial name
- NCT03184272
- Testing
- baseline alert 1, Anti-Trendelenburg-position (ATB), ATB in narcosis
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Schleswig-Holstein
Major Abdominal Surgeries, Mechanical Ventilation
Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study
This study will include patients aged 50 and older scheduled for elective abdominal oncologic surgery, classified as ASA II and III due to increased anaesthetic and surgical risk. Gender will not be a stratification factor.
- Trial name
- IMMEDIUM (NCT07339449)
- Testing
- Multimodal monitoring
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital Dubrava
Cardiac Surgical Procedures, Continuous Positive Airway Pressure
Effects of Non-invasive Ventilation in Patients Undergoing Heart Surgery
The goal of this randomized controlled clinical trial is to compare effects of non-invasive ventilation with different modalities (notably CPAP and BIPAP) in patients undergoing heart surgery.
- Conditions
- Cardiac Surgical Procedures, Continuous Positive Airway Pressure, BIPAP Biphasic Intermittent Positive Airway Pressure
- Trial name
- NCT05966337
- Testing
- CPAP, BIPAP, Usual care in phisicaltherapy
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Myocardial Infarction
Studying the Effectiveness of Early Invasive Treatment in Elderly Patients With High-risk Non-ST-segment Elevation Acute Coronary Syndrome.
The goal of this is observational study is to compare about MACE events and predisposing factors related to MACE events in elderly patients with high-risk non-ST acute coronary syndromes receiving early versus late invasive…
- Trial name
- NCT06486233
- Where
- Vietnam
- Volunteers
- 385 people
- Sponsor
- Gia Dinh People Hospital
Arrhythmia
A Multi-centre Study Comparing the Effects of AZD2927 and Placebo on the Electrical Activity in the Heart in Patients
Medical Products Agency
- Trial name
- NCT01396226
- Testing
- AZD2927
- Where
- 5 sites in Norway, Sweden
- Volunteers
- 20 people
- Sponsor
- AstraZeneca
Cardiac Surgical Procedures, High-risk Surgical Patient
A New Non-invasive Marker to Detect Silent Hypoxia in Patients Undergoing Cardiac Surgery
In patients undergoing cardiac surgery under cardiopulmonary bypass, some organs like brain and heart are preserved while others (skin, gut and skeletal muscle) are being underperfused.
- Conditions
- Cardiac Surgical Procedures, High-risk Surgical Patient, Anaerobic Threshold
- Trial name
- NCT01560611
- Testing
- Near infrared spectroscopy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France