Clinical trials: Patients Undergoing Laparoscopic Surgery
Hypotension During Surgery
Effect of Titrated Administration of Ciprofol on Perioperative Hypotension in Elderly Patients Undergoing Laparoscopic Abdominal Surgery: A Randomized Controlled Trial
Elderly patients are frequently burdened with age-associated comorbidities and frailty, accompanied by physiological changes such as vascular stiffening, cardiac dysfunction, and impaired autonomic regulation.
- Trial name
- TAPH (NCT07328958)
- Testing
- titrated anesthesia
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Gastric Cancer, Laparoscopic Surgery
Early Jejunostomy Nutrition Minimizes Time to Chemotherapy
Adjuvant chemotherapy (AC) for gastric cancer is known to improve prognosis, and longer time to AC is associated with worse survival.
- Conditions
- Gastric Cancer, Laparoscopic Surgery, Chemotherapy
- Trial name
- NCT01766765
- Testing
- Jejunostomy, Early oral nutrition
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jinling Hospital, China
Atelectasis, Pulmonary Complications
Low-Flow Anesthesia and Perioperative Atelectasis in Laparoscopic Bariatric Surgery
The goal of this clinical trial is to learn whether low-flow anesthesia reduces perioperative atelectasis compared to normal-flow anesthesia in adults undergoing laparoscopic bariatric surgery.
- Conditions
- Atelectasis, Pulmonary Complications, Ultrasonography, Bariatric Surgery
- Trial name
- NCT07041567
- Testing
- Sevoflurane with normal-flow anesthesia, Sevoflurane with low-flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Anesthesia
TEAS to Improve Outcome During Emergence From General Anesthesia After Robotic Surgery
This study is to observe whether transcutaneous electrical stimulation at specific acupoints could improve the quality of emergence in patients undergoing robotic laparoscopic gynecologic surgery.
- Trial name
- TIGER (NCT02323958)
- Testing
- acupoint stimulation, non-acupoint stimulation, electrode attached
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Air Force Military Medical University, China
Postoperative Pain
Percutaneous Ketamine Versus Lidocaine or Placebo, for Post-Surgery Analgesia, in Patients Undergoing Laparoscopic Partial Lung Resection
Since VAT bears with it severe postopearive pain, and since ketamine has been shown to be an optimal analgesics adjuvant for postoperative pain, we wish to assess to effects of ketamie vs.
- Trial name
- NCT00822133
- Testing
- lidocaine, ketamine, non-active drug cream
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Low-flow Anesthesia
High vs. Low Flow Sevoflurane Anesthesia in Pediatric Laparoscopic Surgery: Recovery, Hemodynamics, and Cost Comparison
The primary objective of our study is to compare the effects of different flow rates of the routinely used inhalation agent, sevoflurane, on postoperative recovery times in pediatric patients undergoing elective laparoscopic…
- Trial name
- NCT06676969
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Postoperative Pain
Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy Surgery
The primary purpose of this study is to determine if CR845 is effective in treating the pain associated with a laparoscopic hysterectomy.
- Trial name
- NCT01361568
- Testing
- CR845
- Where
- 18 sites in United States
- Volunteers
- 203 people
- Sponsor
- Cara Therapeutics, Inc.
Gallbladder Disease
Effect IV Ibuprofen and Inflammatory Responses
This study is being done because the investigators wish to study ways to improve recovery after surgery. Injury, including surgical injury, causes inflammation.
- Trial name
- NCT01938040
- Testing
- ibuprofen
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Laparoscopic Surgery
The Impact of Anesthesia and Positioning on Cerebral Blood Flow and Pressure in Patients Undergoing Laparoscopic Surgery
The aim of this observational study was to understand the effect of ReverseTrendelenburg position, Trendelenburg position on intracranial pressure and carotid blood flow in patients undergoing laparoscopic surgery.
- Trial name
- NCT06669689
- Testing
- operating position, pneumoperitoneum
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiaguang Duan
Postoperative Pain
Melatonin and Its Effect on the Perioperative Opioid Needs in Pediatric Patients Undergoing Laparoscopic Surgery.
To study the role of Preoperative Melatonin adminsteration in pediatric patients undergoing laparoscopic surgeries regarding its analgesic and sedative effects
- Trial name
- NCT05728892
- Testing
- Melatonin 3 MG
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cholecystectomy, Elective Surgery
Comparison Of Dexmedetomidine and Fentanyl In Attenuation Of Hemodynamic Response To Direct Laryngoscopy And Intubation In Patient Undergoing Laparoscopic Cholecystectomy.
Compare effects of intravenous dexmedetomidine and fentanyl in attenuation of intubation response in a patient undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04089592
- Testing
- Dexmedetomidine, Fentanyl
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Anesthesia, Regional Anesthesia
M-Tapa Block vs External Oblique Intercostal Block for Laparoscopic Sleeve Gastrectomy Surgery
In obese patients, adequate pain relief in the postoperative period is an important parameter that affects patient comfort and hospital stay.
- Conditions
- Anesthesia, Regional Anesthesia, Postoperative Pain
- Trial name
- NCT05939635
- Testing
- Bilateral ultrasound guided external oblique intercostal block (EOIB), Bilateral ultrasound guided Modified thoracoabdominal nerves block through perichondrial approach(M-TAPA) block, IV morphine patient-controlled analgesia (PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ondokuz Mayıs University
Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
Application of a New Surgical Technique in Proximal Gastrectomy: a Prospective, Multicenter Randomized Controlled Study
This is a prospective study using a multicenter, randomized, controlled, open label, and efficacy validated approach.At present, there is no universally recognized optimal method for gastrointestinal reconstruction after proximal…
- Trial name
- NCT06679244
- Testing
- Totally laparoscopic proximal gastrectomy with Hao's esophagogastrostomy by fissure technique, Totally laparoscopic proximal gastrectomy with double-tract reconstruction
- Where
- 3 sites in China
- Volunteers
- 52 people
- Sponsor
- Huashan Hospital
Fatigue Symptom, Blood Pressure Variability
Association Between Intraoperative Mean Arterial Pressure Variability and Postoperative Fatigue in Patients Undergoing Laparoscopic Abdominal Surgery
This prospective cohort study aims to investigate the relationship between intraoperative mean arterial pressure (MAP) variability and postoperative fatigue syndrome (POFS) in elderly patients (≥18 years) undergoing laparoscopic…
- Trial name
- NCT07481006
- Where
- China
- Volunteers
- 366 people
- Sponsor
- The First People's Hospital of Lianyungang
Neuromuscular Blockade
Deep vs Moderate Block: Impact on Operating Conditions & Patient Satisfaction
This study compares surgeon's satisfaction of operating conditions and patient's satisfaction following laparoscopic gynecological surgeries in two groups of patients, half of whom will receive deep neuromuscular blockade and the…
- Trial name
- NCT02794714
- Testing
- Deep neuromuscular blockade, Moderate neuromuscular blockade
- Sponsor
- Kuala Lumpur General Hospital
Gynecologic Laparoscopic Surgery, Hysterectomy
Impact of Nociceptive-Level (NOL) Intraoperative Guided Analgesia During Gynecological Laparoscopic Surgery Under General Anesthesia
The aim of the present study is to show that the use of the NOL device in addition to the Standard of Care (based on mean arterial blood pressure and heart rate values) to guide the administration of opioids compared to the…
- Conditions
- Gynecologic Laparoscopic Surgery, Hysterectomy, Oophorectomy
- Trial name
- NOLGYN (NCT03776838)
- Testing
- Intravenous Fentanyl guided by SoC+NOL, Intravenous Fentanyl guided by SoC
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
ESPB With Dexmetomidine May Provide Analgesia
Analgesic Efficacy of Adding Different Doses of Dexmedetomidine as Adjuvants With Bupivacaine vs.Bupivacaine Only in Ultrasound-guided Erector Spinae Plane Block in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery. A Randomized Controlled Double Blinded Study.
Analgesic Efficacy of adding different doses of dexmedetomidine as adjuvants with bupivacaine vs. bupivacaine only in ultrasound-guided erector spinae plane block in morbidly obese patients undergoing Laparoscopic Bariatric…
- Trial name
- NCT07380503
- Testing
- Analgesic Efficacy of adding different doses of dexmedetomidine
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Nausea and Vomiting
The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
This study was designed to compare the effects of gabapentin and ramosetron on PONV in patients undergoing laparoscopic gynecologic surgery.
- Trial name
- PONV (NCT02617121)
- Testing
- Gabapentin, Ramosetron, Gabapentin and Ramosetron
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
Prospective Comparison of Surgical Outcomes With Using Integrated Robotic Technology Versus Conventional Laparoscopy for Gastric Cancer Surgery
Despite the theoretical superiority of robotic technology, surgical outcomes following robotic surgery have shown little benefit over conventional laparoscopic surgery.
- Trial name
- NCT03396354
- Testing
- Integrated robotic surgery, Conventional laparoscopic surgery
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Yonsei University
Laparoscopic Sleeve Gastrectomy, Subcostal Transversus Abdominis Plane Block
Unilateral TAP Block for Laparoscopic Gastric Sleeve Surgery
The study team will be assessing if the unilateral subcostal transversus abdominis plane (TAP) block can decrease pain and improve outcomes following laparoscopic sleeve gastrectomy surgeries.
- Trial name
- NCT03856788
- Testing
- Saline, Bupivacaine
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Icahn School of Medicine at Mount Sinai