Clinical trials: Patients Undergoing Laparoscopic Surgery
Laparoscopic Surgery, Target Controlled Infusion
Comparison of Target Controlled Infusion Anesthesia and Inhalation Anesthesia in Pediatric Laparoscopic Surgeries
Comparison of Target Controlled Infusion Anesthesia and Inhalation Anesthesia in Pediatric Laparoscopic Surgeries
- Trial name
- NCT06571682
- Testing
- Target Controlled Infusion, Inhalation anesthetic
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Dexmedetomidine, Hemodynamics
Preoperative Nebulized Dexmedetomidine on Hemodynamic Changes in Laparoscopic Bariatric Surgery.
This randomized study aims to evaluate the effect of preoperative dexmedetomidine nebulization on blunting hemodynamic response for laryngoscope, intubation and pneumoperitoneum in morbidly obese patients undergoing laparoscopic…
- Conditions
- Dexmedetomidine, Hemodynamics, Laparoscopic Bariatric Surgery
- Trial name
- NCT06014359
- Testing
- Saline, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Postoperative Nausea and Vomiting
Midazolam Versus Dexamethasone-ondansetron in Preventing Postoperative Nausea-vomiting for Laparoscopic Surgeries
Postoperative nausea and vomiting(PONV) affects 11 to 60 % of patients undergoing surgery and is a major cause of postoperative morbidity.
- Trial name
- NCT03603119
- Testing
- Normal saline, Midazolam, Dexamethasone, ondansetron
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institute of Liver and Biliary Sciences, India
Patients Undergoing Laparoscopic Surgery
Quantitative Analysis of EEG Changes in Response to Nociception
This study will quantify the nociception using Analgesia Nociception Index (ANI) during general anesthesia and analyze the differences in EEG depending on the degree of nociception.
- Trial name
- NCT06342570
- Testing
- There is no Intervention name to describe.
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Gangnam Severance Hospital
Obesity, Bariatric Surgery Candidate
Effects of Recruitment Manouever on Oxygenation, Oxygen Reserve Index and Postoperative Pulmonary Complications
General anesthesia and mechanical ventilation decrease pulmonar volume; attenuate small airway closure, atelectasis, and increase the rate of hypoxia and postoperative pulmonary complications.
- Trial name
- NCT05705245
- Testing
- recruitment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Balikesir University
Prostate Cancer
The Effect of Propofol Based Total Intravenous Anesthesia on Oxidative Stress and Nitric Oxide
Robot assisted laparoscopic radical prostatectomy(Robot-LRP) requires pneumoperitoneum and trendelenburg position which result in oxidative stress and inflammatory response.
- Trial name
- NCT02149628
- Testing
- propofol, Desflurane
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Optic Nerve Sheath Diameter
Changes of Optic Nerve Sheath Diameter Between Obese and Non-obese Patients Undergoing Laparoscopic Gynecological Surgery
This study aims to compare the change of optic nerve sheath diameter in obese and non-obese patients undergoing laparoscopic gynecological surgery in a steep Trendelenburg position.
- Trial name
- NCT04427085
- Testing
- Ultrasound assessment of optic nerve sheath diameter
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- SMG-SNU Boramae Medical Center
Post Operative Pain
A Comparison Between The Efficacy of Modified Thoracoabdominal Plane Block Via Perichondral Approach (M-TAPA) And External Oblique Intercostal Plane Block (EOIPB) in Patients Undergoing Laparoscopic Cholecystectomy Surgeries (LC)
Because laparoscopic procedures have a number of benefits over open procedures, they have completely changed the surgical industry.(1) Laparoscopic cholecystectomy (LC) is a minimally invasive technique that usually yields less…
- Trial name
- NCT06810206
- Testing
- Bilateral Ultrasound Guidance M-TAPA, Bilateral Ultrasound Guidance EOIPB
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery
Effect of Subanesthetic Dose of Esketamine on Sleep Quality and Recovery of Gastrointestinal Function in Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery in the Early Postoperative Period
Patients undergoing gynecological surgery are at high risk of developing postoperative sleep disorders. Intraoperative opioid use is detrimental to the patient's postoperative recovery of gastrointestinal function.
- Trial name
- NCT05715671
- Testing
- esketamine
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Zhuan Zhang
General Anesthesia, Elective Laparoscopic Cholecystectomy
The Effect of Positive End-Expiratory Pressure Levels on Perfusion Index and Neurocognitive Functions in Geriatric Patients
With the increasing geriatric population, age-related physiological changes and common comorbidities increase the risk of surgical and anesthesia-related complications in this patient group.
- Trial name
- NCT07505550
- Testing
- PEEP levels
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Ankara City Hospital Bilkent
Obesity, Bariatric Surgery
Comparison of Epidural and Intravenous Analgesia in Laparoscopic Sleeve Gastrectomy Patients
This retrospective observational study aimed to compare the effects of epidural analgesia and intravenous analgesia on early postoperative pulmonary function in patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy
- Trial name
- EAvs IV in LSG (NCT07712224)
- Testing
- Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution), Intravenous analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
PEEP by Lung Ultrasound, PEEP With Dynamic Compliance
Postoperative Diaphragm Function in Pediatric Laparoscopic Abdominal Surgery Using Compliance and PEEP Guided by Lung Ultrasound
Protective ventilation strategies and alveolar recruitment maneuvers (ARM) are employed in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) to improve oxygenation, prevent alveolar collapse…
- Trial name
- NCT07126067
- Testing
- Lung Ultrasound and PEEP Application, Application of PEEP with Dynamic Compliance
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Konya City Hospital
Glycopyrrolate
Effect of Perioperative Use of Glycopyrrolate on Lung Function in Patients Under General Anesthesia
Gastrointestinal tumor is one of the highest incidence of malignant tumors in our country, with the incidence increasing year by year.
- Trial name
- NCT05693246
- Testing
- Glycopyrrolate, normal saline
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Zhuan Zhang
Kidney Cancer
Hydroxyethyl Starch and Renal Function After Laparoscopic Nephrectomy
The purpose of this project is to investigate if hydroxyethyl starch (HES) is potential nephrotoxic and examine the effects on the circulation and kidneys during administration of HES during surgery.
- Trial name
- VONE (NCT01486550)
- Testing
- Voluven (Hydroxyethyl starch 130/0,4), Sodium Chloride 9mg/ml
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Regional Hospital Holstebro
Analgesic Efficacy of M-TAPA Block Accomplished Prior to Surgery in Patients Undergoing Laparoscopic Gynecological Surgeries
Modified Thoracoabdominal Nerves Block Through Perichondrial Approach: a New Strategy With a Wide Range of Utilization in Laparoscopic Gynecological Surgeries.
The current study was to assess the analgesic effects of the modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) block in patients undergoing gynecological laparoscopic surgeries.The primary goal was to…
- Trial name
- NCT06039423
- Testing
- The M-TAPA block, Ketorolac
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Anesthesia, Surgery--Complications
Intraoperative Protective Ventilation for Obese Patients Undergoing Gynaecological Laparoscopic Surgery
Background. The use of a comprehensive strategy providing low tidal volumes, peep and recruiting maneuvers in patients undergoing open abdominal surgery improves postoperative respiratory function and clinical outcome.
- Trial name
- Inprove4large (NCT03157479)
- Testing
- Intravenous anesthetic, Crystalloid Solutions, Esophageal pressure measurement
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Catholic University of the Sacred Heart
Postoperative Nausea and Vomiting, Colorectal Neoplasms
Acupuncture for Postoperative Nausea and Vomiting in Patients Undergoing Colorectal Surgery
Background: PONV is one of the prevalent discomforts in the early phase of recovery after surgery. Evidence suggests that the stimulation of the P6 acupuncture point can reduce the occurrence of PONV.
- Trial name
- AcuPONV (NCT02509143)
- Testing
- High-dose acupuncture with intravenous infusion of ramosetron, P6 stimulation with intravenous infusion of ramosetron, Intravenous infusion of ramosetron
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Pusan National University Yangsan Hospital
Cholelithiasis
Effects of Postoperative Video-assisted Early Mobilization on Recovery Outcomes
This randomized controlled trial aims to evaluate the effects of video-assisted early mobilization education on postoperative recovery in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07512024
- Testing
- Video-Assisted Early Mobilization Training
- Volunteers
- 44 people
- Sponsor
- Muş Alparslan University
Postoperative Pain
Ultrasound Guided Transversus Abdominis Plane Block in Pediatric Surgery
The primary objective of this study is to assess differences in postoperative pain experienced by pediatric patients having transversus abdominis plane block block with bupivacaine (0.125% and 0.25%) compared with control group…
- Trial name
- NCT02723487
- Testing
- Bupivacaine 0.125%, Bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Abdelrady S Ibrahim, MD
Robotic Surgical Procedures
Haemodynamic Changes During Robotic Prostatectomy
The aim of the study is to analyse the haemodynamic and ventilatory changes in patients undergoing robotic prostatectomy, compared to standard laparoscopic prostatectomy.
- Trial name
- NCT04235387
- Where
- 2 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Czech Technical University in Prague