Clinical trials: Patients Undergoing Laparoscopic Surgery
Sore Throat, Pain
Post Operative Sore Throat and Dexamethasone
Sore throat is a common postoperative complaint that can lead to morbidity and patient dissatisfaction . The incidence of sore throat has been reported to be between 6% and 90% even under optimal intubating conditions.
- Trial name
- NCT01052038
- Testing
- Dexamethasone 0.05mg/kr administration, Dexamethasone 0.1mg/kg
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Colorectal Cancer
RADOX' Reduced Abdominal Distension and Oxygen Delivery
The use of laparoscopic surgery is continuing to increase in colorectal resection and expected reach 80% in the next 10 years. Although laparoscopic (keyhole) or minimally invasive surgery can lead to faster recovery it can also…
- Trial name
- RADOX (NCT02045680)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Dr Michael Scott
Gallstone Disease, Postoperative Pain
TENS for Anxiety, Pain, and Satisfaction After Laparoscopic Cholecystectomy
This study is designed to evaluate whether Transcutaneous Electrical Nerve Stimulation (TENS) can improve recovery for patients undergoing laparoscopic gallbladder removal surgery (laparoscopic cholecystectomy).
- Conditions
- Gallstone Disease, Postoperative Pain, Surgical Anxiety, Patient Satisfaction After Laparoscopic Cholecystectomy
- Trial name
- TENS-LC (NCT07307703)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Emergence Agitation, Remimazolam Besylate
Effect of Rematazolam Besylate, Propofol, and Sevoflurane Perioperative Sedation on Incidence of Emergence Agitation and Hemodynamics in Patients Undergoing Laparoscopic Abdominal Surgery
Emergence agitation (EA) is a transient, self-limited, non-fluctuating state of psychomotor excitement, which closely revolves around the emergence of general anesthesia.
- Conditions
- Emergence Agitation, Remimazolam Besylate, Perioperative Sedation, Laparoscopic Abdominal Surgery
- Trial name
- NCT05624424
- Testing
- Rematazolam Besylate, Propofol, Sevoflurane
- Where
- 6 sites in China
- Volunteers
- 1,317 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Postoperative Hypoxemia
Postoperative SpO₂/FiO₂ Ratio and Analgesic Methods in Laparoscopic Surgery
This prospective observational study aims to evaluate the association between postoperative oxygenation, assessed by the SpO₂/FiO₂ ratio, and body mass index (BMI), STOP-BANG score, and postoperative analgesic methods in patients…
- Trial name
- NCT07401589
- Testing
- Standard of Care
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istinye University
Atelectasis, Postoperative Pulmonary Complications (PPCs)
Automated Intraoperative Lung Recruitment Maneuvers in Major Laparoscopic Surgery
Laparoscopic colorectal surgery is associated with an increased risk of intraoperative atelectasis due to pneumoperitoneum, Trendelenburg positioning, and prolonged anesthesia duration.
- Trial name
- NCT07349784
- Testing
- Automated Intraoperative Lung Recruitment Maneuvers
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue
The Effect of TEAS on the Quality of Early Recovery
During the past four decades, gynecologic laparoscopy has evolved from a limited method to an advanced operative approach that frequently serves as a substitute for laparotomy.
- Conditions
- C.Delivery; Surgery (Previous), Gynecological, Inappropriate Device Stimulation of Tissue, Delayed Emergence From Anesthesia
- Trial name
- NCT02619578
- Testing
- TEAS, Con, propofol, remifentanil, vecuronium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guizhou Provincial People's Hospital
Female Patients Undergoing Laparoscopic Abdominal Surgery
Palonestron, Granisetron and Ramosetron for Prevention of Postoperative Nasea and Voming After Laparoscopic Abdominal Surgery
We compared the prophylactic anti-emetic efficacy of ramosetron, a newly developed 5-HT3 antagonist, granisetron and ondansetron in patients at high-risk for postoperative nausea and vomiting after laparoscpic abdominal surgery.
- Trial name
- NCT01752374
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Gachon University Gil Medical Center
C.Surgical Procedure; Gastrointestinal
Triple Therapy for Postoperative Nausea and Vomiting in Laparoscopic Gastrointestinal Surgery
Postoperative nausea and vomiting (PONV) are common in patients, especially in patients at high risk. PONV may result in prolonged hospital stay and threaten patients' life.
- Trial name
- NCT04853147
- Testing
- palonosetron, dexamethasone, and fosaprepitant dissolved in 0.9% NaCl, palonosetron, dexamethasone, and 0.9% NaCl
- Where
- China
- Volunteers
- 1,154 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Atelectasis, Atelectases, Postoperative Pulmonary
Evaluation of Effect of Different Ventilator Mods on Atelectasis in Patients Undergoing Laparoscopic Surgery
In this study researchers aim to evaluate effect of different ventilation modalities on the developments of atelectasis by using ultrasound.
- Trial name
- PCV-VG (NCT03614845)
- Testing
- VCV, PCV-VG, lung ultrasonography
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Breast Lumpectomy, Laparoscopic Cholecystectomy
De-Implementation of Low-value Testing in Patients Undergoing Low-Risk Surgery
This trial aims to evaluate the effectiveness of a multi-level, multi-component de-implementation strategy to reduce unnecessary preoperative testing.
- Conditions
- Breast Lumpectomy, Laparoscopic Cholecystectomy, Inguinal Hernia Repair
- Trial name
- NCT06934564
- Testing
- Active de-Implementation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Michigan
Mechanical Ventilation During Anesthesia
Lung Ultrasound Versus Dynamic Lung Compliance to Detect the Optimum PEEP After Alveolar Recruitment for Patients Undergoing Laparoscopic Gastric Sleeve Surgery
The aim of this study is to evaluate The role of transthoracic lung US as a clinical tool in Comparison to dynamic lung compliance for detection of optimum PEEP for obese patients undergoing laparoscopic gastric sleeve surgery.
- Trial name
- NCT04704596
- Testing
- anesthesia ventilator machine, lung ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Postoperative Pain, Ventral Hernia
Mesh Fixation With Intraperitoneal Tisseel
The purpose of this study is to determine whether mesh fixation in laparoscopic umbilical hernia repair with fibrin glue is superior to tacks in terms of postoperative pain and recovery.
- Trial name
- MEFIXIT (NCT00842842)
- Testing
- tack fixation of mesh, glue fixation of mesh
- Where
- 4 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Herlev Hospital
Atelectasis, Perioperative Oxygenation
Individualized vs Standard PEEP and Oxygen Reserve Index in Laparoscopic Hernia Surgery
During laparoscopic surgery under general anesthesia, lung function can be affected by increased abdominal pressure and patient positioning.
- Conditions
- Atelectasis, Perioperative Oxygenation, Laparoscopic Inguinal Hernia Repair, Mechanical Ventilation
- Trial name
- NCT07775573
- Testing
- Standard PEEP Ventilation, Individualized PEEP Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Aminophylline, Chronic Obstructive Pulmonary Disease
Aminophylline on Perioperative Lung Mechanics in COPD Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery
The aim of this study is to evaluate the usefulness of adding aminophylline to dexmedetomidine intravenous infusion intraoperatively on oxygenation and lung mechanics in chronic obstructive pulmonary disease (COPD) morbidly obese…
- Conditions
- Aminophylline, Chronic Obstructive Pulmonary Disease, Obese, Laparoscopic Bariatric Surgery
- Trial name
- NCT06125665
- Testing
- Aminophylline-Dexmedetomidine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Laparoscopy
Data Collection of Demographics and Perioperative Care of Patients Undergoing Laparoscopic Surgery
The goal of this clinical research study is to collect information on patients who had or are going to have laparoscopy performed at M. D. Anderson.
- Trial name
- NCT00490126
- Testing
- Laparoscopic Surgery Data Collection
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
Laparoscopic Surgery, Pediatrics
Effect of Palonosetron, Ondansetron and Dexamethasone in the Prevention of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) is an important outcome for the patient; patients generally rate PONV as worse than postoperative pain.
- Conditions
- Laparoscopic Surgery, Pediatrics, Nausea and Vomiting, Postoperative, Antiemetics
- Trial name
- NCT05439798
- Testing
- Ondansetron+Dexamethasone, Palonosetron+Dexamethasone, Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Selcuk University
Prostate Cancer Adenocarcinoma, Erectile Dysfunction Following Radical Prostatectomy
Use of Indocyanine Green in Robotic Prostate Surgeries
Imaging of the vascular nerve bundle using Indocyanine Green
- Trial name
- NCT05960149
- Testing
- using Indocyanine Green, Nerve-sparing robot-assisted laparoscopic radical prostatectomy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Neuromuscular Blockade
Deep Neuromuscular Blockade on Postoperative Pain
This study aims to investigate the impact of varying degrees of neuromuscular blockade on postoperative pain in pediatric patients aged over 2 months to under 7 years undergoing laparoscopic surgery under general anesthesia.
- Trial name
- NCT06679569
- Testing
- rocuronium 0.2 mg/kg/hr continuous infusion, rocuronium 0.6 mg/kg/hr continuous infusion
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Seoul National University Hospital
Laparoscopic Cholecystectomy, Ultrasonography
Ultrasonography vs Intraoperative Laparoscopic Cholecystectomy for Gall Stone Disease
This research is designed to correlate between intraoperative status of gallstone disease patients with their USG findings. The key question it aims to answer is: Does the ultrasonography predict laparoscopic cholecystectomy will…
- Conditions
- Laparoscopic Cholecystectomy, Ultrasonography, Difficult Surgery
- Trial name
- NCT07530874
- Testing
- laparoscopic cholecystectomy
- Where
- Nepal
- Volunteers
- 130 people
- Sponsor
- Nepal Medical College and Teaching Hospital