Clinical trials: Patients Undergoing Spine Surgery
Diet, Carbohydrate Loading
Carbohydrate Loading and Elderly Patients Undergoing Spine Surgery
Carbohydrate loading, the consumption of carbohydrates prior to surgery, is an example of preoperative nutrition that has provided many benefits to surgical patients.
- Trial name
- NCT05778487
- Testing
- Gatorade Thirst Quencher
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- Horizon Health Network
Dysphagia
Effects of 3% Sodium Chloride on Post-operative Dysphagia Following Anterior Cervical Spine Surgery
Post-operative dysphagia is a significant issue following anterior cervical spine surgery. The investigators are studying the effects of perioperative 3% sodium chloride, given over a period of 24 hours, on post-operative…
- Trial name
- NCT03677310
- Testing
- 3% Sodium Chloride, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Pain
Effect of Perioperative Intravenous Lidocaine on Postoperative Quality of Recovery in Patients Undergoing Spine Surgery
Acute postoperative pain is an unpleasant, unwanted sensory and emotional experience for the patient. The investigators seek to determine if the addition of systemic lidocaine can improve the quality of recovery after spine…
- Trial name
- NCT01930877
- Testing
- Lidocaine
- Where
- United States
- Sponsor
- Baylor College of Medicine
Opoid Managment, Pain Management
Effect of Opioid-Sparing Anesthesia on Postoperative Opioid Consumption and Pain in Elderly Patients Undergoing Spine Surgery
The goal of this clinical trial is to learn if an anesthesia management strategy called opioid-sparing anesthesia could help reduce postoperative opioid consumption, pain intensity and enhance recovery in elderly patients…
- Trial name
- NCT07588802
- Testing
- Opioid-Sparing Protocol, Routine anesthesia protocol
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Lumbar Spine Surgery, Hemodynamic Changes
IVC Collapsibility Index in Lumbar Stabilization Surgery
This study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia.
- Conditions
- Lumbar Spine Surgery, Hemodynamic Changes, Intravascular Volume Status
- Trial name
- NCT07549165
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Spinal Surgery, Prone Position
A Prospective Observational Study on Factors Affecting Optic Nerve Sheath Diameter and Visual Acuity in Prone Spinal Surgery
The prone position in spinal surgery can alter intracranial pressure and optic nerve sheath diameter (ONSD) and potentially lead to visual complications.
- Trial name
- PRONE-ONSD (NCT07395115)
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Istanbul University - Cerrahpasa
Spine Surgery
The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.
This study will investigate whether a combination of three anesthetic medications will reduce intraoperative and postoperative pain in patients undergoing complex spine surgery, and whether it will reduce the use of opioid pain…
- Trial name
- NCT07365800
- Testing
- Methadone-dexmedetomidine-ketamine combination
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- University of Missouri-Columbia
Pain, Postoperative, Postoperative Nausea and Vomiting
Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery
There will be two groups in this study: one group will be given the standard infusion of naloxone, a drug which helps reduce side effects from opioids needed after surgery, and the other group will receive a higher dose.
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Scoliosis
- Trial name
- NCT01531439
- Testing
- Naloxone
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Children's Mercy Hospital Kansas City
Ileus
Effect of Chewing Gum on Post-operative Ileus (GUMPI)
The purpose of this study is to determine whether chewing gum post-operatively decreases the time to first flatus or defecation in patients undergoing spine surgery as a indirect indicator of post-operative ileus.
- Trial name
- GUMPI (NCT02847364)
- Testing
- chewing gum
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Artifical Intelligence, Bispectral Index
Bispectral Index in Patients Undergoing Vertebral Surgery Using Artificial Intelligence Programs: A Methodological Study
This study aims to interpret the Bispectral Index (BIS) monitoring method, which we routinely use for monitoring in scoliosis surgery, with artificial intelligence (AI) tools and to determine the accuracy and reliability of AI…
- Conditions
- Artifical Intelligence, Bispectral Index, Spine
- Trial name
- BIS (NCT07650604)
- Testing
- CHATGPT Group, GEMİNİ group, COPİLOT group
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Antalya Health Sciences University
Spinal Diseases
Effect of PEEP on Intraoperative Hypothermia
Intraoperative hypothermia is associated with many clinical adverse outcomes. Many techniques were applied to prevent intraoperative hypothermia, and positive end-expiratory pressure (PEEP) has been known to blunt intraoperative…
- Trial name
- NCT02416557
- Testing
- PEEP
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Seoul National University Hospital
Obesity & Overweight, Lumbar Spine Surgery
Sevoflurane vs Propofol Anesthesia in Obese Patients Undergoing Lumbar Surgery
This randomized, single-center, single-masked clinical trial aims to compare the immunomodulatory effects of sevoflurane-based inhalational anesthesia and propofol-based total intravenous anesthesia in obese patients undergoing…
- Trial name
- NCT07611240
- Testing
- Propofol (Astra-Zeneca), Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Degenerative Lumbar Spine Diseases, Lumbar Spinal Instability
Role of Intraoperative Computed Tomography in Assessment of Spine Instability in Lumbar Degenerative Disease
This study examines how well computed tomography (CT) imaging performed during spine surgery - known as intraoperative CT - can detect instability in the lower (lumbar) part of the spine.
- Conditions
- Degenerative Lumbar Spine Diseases, Lumbar Spinal Instability, Degenerative Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- INSIGHT-CT (NCT07644507)
- Testing
- Intraoperative Computed Tomography (O-arm)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
POCD, Anemia
The Impact of Perioperative Transfusion on Postoperative Cognitive Dysfunction
Although blood transfusion is a representative treatment for acute anemia due to blood loss during surgery, it is also a powerful risk factor for postoperative cognitive dysfunction.
- Conditions
- POCD, Anemia, Transfusion
- Trial name
- NCT04155489
- Testing
- blood transfusion
- Where
- South Korea
- Volunteers
- 148 people
- Sponsor
- Gangnam Severance Hospital
Spine Surgery
Effect of TIVA With Magnesium Sulfate on IONM in Patients Undergoing Spine Surgery
Anesthesia for neurosurgery requires balancing deep and effective anesthesia as well as postoperative analgesia versus the risks of delayed recovery and postoperative respiratory depression.
- Trial name
- NCT04716439
- Testing
- Spine Surgery
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- King Khalid University Hospital
PONV
Effect of Combination Dexmedetomidine Added to Fentanyl-based Intravenous Patient-controlled Analgesia on Nausea Vomiting in Highly Susceptible Patients Undergoing Lumbar Spinal Surgery: Prospective Double Blinded Randomized Controlled Trial
The aim of this study is to test the hypothesis that addition of dexmedetomidine to fentanyl-based intravenous patient controlled analgesia (PCA) reduces requirement of fentanyl bolus and consequent postoperative nausea and…
- Trial name
- NCT01840254
- Testing
- dexmedetomidine, normal saline
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Postoperative Pain, Lumbar Spine Surgery
Postoperative Pain Monitoring With ANI in Lumbar Spine Surgery
This study aims to compare two different pain management methods in patients undergoing elective lumbar spine surgery. Patients are randomly assigned to receive either an ultrasound-guided erector spinae plane block (ESPB) or…
- Trial name
- SPINE-ANI (NCT07455565)
- Testing
- Erector Spinae Plane Block, Intravenous Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Akdeniz University Hospital
Postoperative Pain
Analgesic Efficacy of the Erector Spinae Plane Block Using Bupivacaine Versus Bupivacaine/Magnesium Sulphate in Patients Undergoing Lumbar Spine Surgery
Introduction: Severe postoperative pain following spine surgery is a significant cause of morbidity, extended length of facility stay, and marked opioid usage The analgesic regime for postoperative pain usually includes…
- Trial name
- NCT04433624
- Testing
- Group (B)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Spine Surgery
Safety of Tranexamic Acid in Reducing Bleeding in Adults Undergoing Spinal Surgery
Spinal fusion surgery can be associated with significant blood loss requiring allogeneic blood transfusion. Tranexamic acid is a synthetic amino acid with antifibrinolytic action that has been shown to reduce perioperative blood…
- Trial name
- NCT00444470
- Testing
- Tranexamic acid
- Where
- 3 sites in Canada
- Volunteers
- 151 people
- Sponsor
- University Health Network, Toronto
Spine Surgery
Preoperative Prevention and Early Rehabilitation for Patients Undergoing Elective Spine Surgery
Aim: The aim is to evaluate the outcome after spine surgery when using an integrated program that combined preoperative prevention and early postoperative rehabilitation compared to the routine procedures.
- Trial name
- NCT00459966
- Testing
- Preoperative rehabilitation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet