Clinical trials: Patients Undergoing Spine Surgery
Postoperative Recovery, Lumbar Disc Herniation
Lower Back Muscle Size and Recovery After Lumbar Disc Herniation Surgery
Recovery after surgery for a herniated disc in the lower back differs from person to person. The size of the muscles around the lower spine may be related to recovery, but this relationship is not well understood.
- Trial name
- NCT07768241
- Testing
- Preoperative Psoas and Multifidus Muscle Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Oliceridine Fumarate
Effect of Postoperative Analgesia of Oliceridine Fumarate for Gastrointestinal Function Recovery in Patients Undergoing Lumbar Spine Surgery
Osemitidine fumarate is a novel G protein-biased ligand μ-opioid receptor agonist. Previous studies have confirmed its potent analgesic effects and safety: compared with morphine, it reduces respiratory depression and…
- Trial name
- NCT07307495
- Testing
- Sufentanil, Oiceridine
- Where
- China
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Cardiovascular, Neurologic (Spine), and General Surgery
A Study to Compare Human Thrombin Against Bovine Thrombin in Its Ability to Stop Bleeding After Surgery
The purpose of this study is to see if Human Thrombin is as effective as Bovine Thrombin in stopping surgical bleeding within 10 minutes of application.
- Trial name
- NCT00196534
- Testing
- Human Thrombin, Bovine Thrombin
- Where
- 17 sites in United States
- Volunteers
- 304 people
- Sponsor
- Ethicon, Inc.
Spine Tumor, Spine Metastases
Spine Oncology Registry
This is an observational study to evaluate hardware related and oncologic outcomes in adult patients with primary and metastatic spine disease undergoing separation surgery followed by radiation treatment.
- Conditions
- Spine Tumor, Spine Metastases, Spine Cancer
- Trial name
- NCT07225491
- Where
- 5 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Prone Position, Blood Volume
The Effect of High vs. Low Fluid Volume on Ocular Parameters in Prone Spine Surgery
The purpose of this trial is to compare the effect of different fluid volume infusion on ocular parameters in patients undergoing spine surgery in prone position.
- Conditions
- Prone Position, Blood Volume, Intraocular Pressure
- Trial name
- NCT03890510
- Testing
- Ringer's Lactate solution, Spine surgery under general Anesthesia in the prone position
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Huashan Hospital
Intubation, Intratracheal
Intubation Success Rate_Rigid Video Stylet Vs Video Laryngoscope
This study compare the intubation success rate between video laryngoscope and rigid video stylet in cervical spine surgery patients.
- Trial name
- NCT02769221
- Testing
- Rigid video stylet, Video laryngoscope
- Volunteers
- 370 people
- Sponsor
- Seoul National University Hospital
Sleep Disturbance, Anesthesia; Adverse Effect
Effects of Anesthetics and Surgery on Sleep Quality in Patients Undergoing Posterior Spinal Instrumentation Surgery
Investigators aimed to evaluate the impact of the anesthesia method and surgical procedure on the sleep patterns and sleep quality of patients undergoing posterior spinal instrumentation using the Pittsburgh Insomnia Rating…
- Trial name
- NCT06523881
- Testing
- Sevoflurane (Sevorane® liquid 100%, Abbvie Pharmaceuticals, Istanbul, Turkey), Propofol (Propofol-PF® 1% (Polifarma Pharmaceuticals, Tekirdag, Turkey)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uludag University
Cervical Spine Instability
Comparing Ease of Endotracheal Intubation Using C Blade and D Blade of CMAC Videolaryngoscope in Patients Undergoing Elective Cervical Spine Surgery
This study was done to compare the ease of tracheal intubation using the conventional C blade and the D blade of CMAC videolaryngoscope in patients undergoing cervical spine surgery.
- Trial name
- NCT05561231
- Testing
- Intubation with C blade, Intubation with D blade
- Where
- India
- Volunteers
- 68 people
- Sponsor
- King Edward Memorial Hospital, Mumbai
Spinal Disease
General Anesthesia and Regional Cerebral Oxygenation inSpine Surgery Prone Position
Elderly patients are reportedly at higher risk of postoperative cognitive dysfunction (POCD).The authors hypothesized that the incidence of POCD would be affected by several factors including, the age of the patient, the degree…
- Trial name
- NCT05148637
- Testing
- Maintenance of general anesthesia by Sevoflurane, Maintenance of general anesthesia by Desflurane, Anesthesia was maintained by inhalational anesthesia (total intravenous anesthesia by lidocaine, propfol and fentanyl infusions)
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Coagulation
Use of ROTEM for Multi-level Spine Surgery
The purpose of this study is to obtain coagulation profiles of patients undergoing multi-level spine surgeries with ROTEM® and routine coagulation tests.
- Trial name
- ROTEM (NCT00839995)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Weill Medical College of Cornell University
Pressure Injury
Preventing Pressure Injuries in Patients Undergoing Lumbar Spine Surgery
Background：Pressure injuries (PI) are one of the common comorbidities in surgery, meaning PI that occurs immediately after surgery or within hours to 3 days after surgery. The incidence of PI in spine surgery is about 5% ~ 66%.
- Trial name
- NCT06015139
- Testing
- cotton roll-coated viscoelastic polymer pads, viscoelastic polymer pads
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Taiwan University of Science and Technology
Pulmonary Complications
Effect of Perioperative Lung Protective Strategies on the Occurrence of Postoperative Pulmonary Complications in Patients Undergoing Lumbar Spinal Surgery in the Prone Position
Postoperative pulmonary complications are main cause of overall perioperative morbidity and mortality in the patients following general anesthesia.
- Trial name
- NCT02373475
- Testing
- Conventional ventilation, Protective lung ventilation
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Yonsei University
Surgical Site Infection
Incisional Negative Pressure Wound Therapy in Patients Undergoing Spine Surgery
Introduction: Posterior post-operative spine wounds involving surgery at multiple levels are known to have higher rates of wound complications relative to other areas of the body.
- Trial name
- NCT03820219
- Testing
- Prevena™ system, Standard sterile wound dressing
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Nova Scotia Health Authority
Delirium in Old Age
The Incidence and Risk Factors of Postoperative Delirium
Delirium is known to be one of the most common postoperative complications in elderly patients undergoing surgery. Because postoperative delirium can affect the length of hospital stay and prognosis significantly, it is important…
- Trial name
- NCT04656379
- Testing
- spine surgery
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Seoul National University Hospital
Orthopedic Disorder of Spine, Smell Disorder
Olfaction Changes in Patients Undergoing Spine Surgery
This observational prospective study evaluates perioperative olfaction alterations, comprising changes in threshold value, discrimination and identification, which occur in spine patients.
- Trial name
- NCT04194788
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Stress
Intermediate Cervical Plexus Block on Stress Response
The aim of the present study is to investigate the effect of Bilateral Ultrasound-Guided intermediate cervical plexus Block combined with general anesthesia on the stress and inflammatory response in patients undergoing anterior…
- Trial name
- NCT06064214
- Testing
- u/s guided intermediate cervical plexus block
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Emergence From Anesthesia
Comparison Between Total Intravenous Anesthesia With Magnesium Sulphate Versus Total Intravenous Anesthesia With Dexmedetomidine in Patients Undergoing Lumbar Spine Surgeries
Although total intravenous anesthesia (TIVA) provides advantages such as accelerated recuperation and diminished postoperative nausea, it also has constraints, such as the potential for hemodynamic instability and inadequate…
- Trial name
- NCT07443163
- Testing
- Dexmedetomidine (Precedex®), magnesium sulfate
- Volunteers
- 40 people
- Sponsor
- Cairo University
Spine Disease
GDFT Based on PPV Compared With Standard Fluid Therapy in Patients Undergoing Complex Spine Surgery: RCT
The investigators will do the Goal directed fluid therapy by protocolized fluid management in the experimental group, using PPV to guide the fluid administration, compare with standard fluid management in patients undergoing…
- Trial name
- NCT03164811
- Testing
- goal directed fluid therapy, Controlled
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Intubation; Difficult or Failed
Comparison of Two Different Lightwand Intubation Techniques in Cervical Immobilized Patients
This study compares two different approaches of lightwand intubation techniques in cervical immobilized patients.
- Trial name
- NCT06119360
- Testing
- Face-to-face approach, Conventional approach
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Postoperative Pain
Peri-Operative Lidocane, Ketamine, or Lidocane and Ketamine Combination, Infusion for Patients Undergoing Spine Surgery
This study has been designed as a controlled clinical trial to evaluate the efficacy of brief lidocaine infusion, brief ketamine infusion and a lidocaine/ketamine combined infusion when added to conventional opioid therapy…
- Trial name
- NCT01983020
- Testing
- Lidocaine, Ketamine, Saline
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Beth Israel Medical Center