Clinical trials: Patients Undergoing Spine Surgery
Metastatic Disease, Spinal Cord Injury
Negative Pressure Wound Therapy vs. Sterile Dressing for Patients Undergoing Thoracolumbar Spine Surgery
The purpose of this study is to determine if the use of the Prevena™ System decreases the rate of subcutaneous seroma, superficial wound dehiscence and infection.
- Conditions
- Metastatic Disease, Spinal Cord Injury, Spinal Degeneration, Spinal Deformity
- Trial name
- NCT03632005
- Testing
- Vacuum Assisted Closure, Sterile dressing
- Where
- Canada
- Volunteers
- 550 people
- Sponsor
- John Street
Anemia, Venous Thrombosis
A Study to Confirm the Safety and Efficacy of Epoetin Alfa (PROCRIT) Administered Perioperatively vs. the Standard of Care in Blood Conservation in Patients Undergoing Major Elective Spinal Surgery (SPINE Study)
This study is designed to investigate the incidence of deep vein thrombosis in patients receiving a perisurgical regimen of epoetin alfa (PROCRIT®) as compared to patients receiving standard of care blood conservation management.
- Trial name
- NCT00211146
- Testing
- epoetin alfa
- Volunteers
- 680 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Patients Undergoing Spine Surgery
The Influence of a Bupivacaine Digital Nerve Block Using Rev G.
The investigators are proposing to continue investigation to improve the accuracy of the SpHb (continuous hemoglobin monitoring device) by administering an intermediate acting digital nerve block in the finger connected to the…
- Trial name
- NCT01750554
- Testing
- intermediate-acting digital nerve block
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, San Francisco
Nursing Care, Spine Surgery
Dependence, Frailty, and Kinesiophobia on Early Postoperative Mobilization and Self-Care Ability in Patients Undergoing Lumbar Disc Herniation Surgery
Lumbar disc herniation is a common condition that may impair physical functioning and reduce independence in activities of daily living.
- Conditions
- Nursing Care, Spine Surgery, Perioperative Care
- Trial name
- NCT07762183
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Aydin Adnan Menderes University
Postoperative Nausea and Vomiting, Scoliosis
A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine Surgery
The aim of this clinical trial is to compare the effectiveness of two Serotonin (5- HT3) receptor antagonist, palonosetron and granisetron, administered along with dexamethasone as a preventive measure against early and delayed…
- Trial name
- PONV (NCT06540885)
- Testing
- Palonosetron (Group P), Granisetron (Group G)
- Where
- 2 sites in Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Postoperative Pain
Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery
The goal of this study is to compare whether oral or intravenous acetaminophen works better for pain control in patients undergoing lumbar spine fusion surgery
- Trial name
- NCT07203079
- Testing
- Acetaminophen Oral Tablet, Acetaminophen infusion
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Stanford University
Asana Adjustment
Effects of Postural Adjustment on Hemodynamics in Patients Undergoing Prone Spine Surgery Under General Anesthesia
The prone position is a special position often used for spinal surgery. As a special position of general anesthesia, after induction of general anesthesia, severe hemodynamic fluctuations often occur when the supine position is…
- Trial name
- NCT05749978
- Testing
- Asana adjustment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhuan Zhang
Spinal Tumors
Liquid Biopsy Following BBB Disruption Using Barrier Disrupting Fields in Patients Undergoing Spine Surgery
Objective: To identify new central nervous system (CNS) biomarkers to be used for blood-derived liquid biopsy once the blood-brain barrier (BBB), specifically the blood-arachnoid barrier (BAB), has been transiently disrupted by…
- Trial name
- BDF002 (NCT07224451)
- Testing
- spinal surgery, BDF
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Anxiety and Fear, Pain, Postoperative
Virtual Reality as a Digital Premed to Alleviate Pain and Anxiety Preoperatively in Patients Undergoing Spine Surgery
The aim of this research study is to evaluate the impact of immersive VR exposure on preoperative anxiety and pain. Additionally, to assess whether VR intervention would significantly alleviate pain and anxiety levels of patients…
- Conditions
- Anxiety and Fear, Pain, Postoperative, Stress
- Trial name
- NCT06917300
- Testing
- Virtual Reality
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Lodz
Dexmedetomidine VS Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
Evaluation of the Analgesic Effect of Dexmedetomidine Versus Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
To determine if the epidural route provide an acceptable analgesia in spine surgeries and avoided the need for excessive IV analgesics.
- Trial name
- NCT03463083
- Testing
- Dexmedetomidine, Bupivacaine, Fentanyl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spine Surgery
Effect of Protein Supplement on Paraspinal Muscles in Spine Surgery
Protein intake in spinal fusion surgery can prevent paraspinal muscle atrophy by maintaining muscle mass, regeneration, and growth.
- Trial name
- NCT04300517
- Testing
- Three sachet of protein supplement to be mixed in with water used daily
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University