Clinical trials: Patients With Chronic Stroke
Chronic Ischemic Stroke
A Study of Modified Stem Cells in Stable Ischemic Stroke
The primary purpose of the clinical study is to determine the safety of a modified stem cell SB623 when administered to chronic, stable ischemic stroke patients.
- Trial name
- NCT01287936
- Testing
- SB623
- Where
- 5 sites in United States
- Volunteers
- 18 people
- Sponsor
- SanBio, Inc.
Stroke
Bilateral Robotic Rehabilitation in Chronic Stroke
This study investigated the effectiveness and neurophysiological correlates of Bilateral Robot-Assisted Training (BRAT) in right-handed individuals with chronic unilateral stroke, focusing on how lesion side (dominant vs.
- Trial name
- BILAT (NCT07145476)
- Testing
- Robotic arm exoskeleton integrated with cognitively engaging serious games
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Carmelo Chisari
Complex Regional Pain Syndromes, Fibromyalgia
Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
Motor neglect describes a loss of function without a loss of strength, reflexes or sensation. Motor neglect has been described in patients with traumatic brain injury, stroke and chronic pain conditions, e.g.
- Conditions
- Complex Regional Pain Syndromes, Fibromyalgia, Stroke, Traumatic Brain Injury
- Trial name
- VERMONT (NCT03887962)
- Testing
- Virtual Environment Biofeedback, Treadmill walking with no Virtual Environment Biofeedback
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Stroke, Acute Hemiplegia, Apraxia
Action Observation Treatment (AOT) as a Rehabilitation Tool
Epidemiological studies report that 85% of stroke survivors show hemiparesis and a percentage ranging from 55% to 75% report upper limb functional impairment.
- Trial name
- AOT (NCT02235350)
- Testing
- Action Observation Treatment (AOT), Observation of videos with no motor content (MNO)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Neuromed IRCCS
Chronic Stroke
Effect of Somatosensory Motor Intergration Training on Post-stroke Upper Limb Function.
Background: Most patients suffer from post-stroke somatosensory and motor impairments, and 50% to 70% of patients in the chronic stage still have upper extremity impairments that severely limit their functional independence and…
- Trial name
- NCT06057584
- Testing
- somatosensory-motor integration training, pure somatosensory training, pure motor training
- Where
- Taiwan
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Chronic Stroke Patient
Relationship Between Balance, Arm Function and Body Awareness in People With Stroke
Stroke is one of the leading causes of long-term disability worldwide and is frequently associated with impairments in balance, upper extremity function, and body awareness.
- Trial name
- NCT07652710
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Baskent University
Stroke
Treatment of Chronic Stroke With IpsiHand
The ultimate goal of this project is to develop a functioning and clinically feasible method for restoring function to motor-impaired stroke survivors. This ultimate goal will be approached through two different means.
- Trial name
- NCT02552368
- Testing
- IpsiHand Device
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stroke, Chronic Stroke Patients
The Safety and Effectiveness of Q Therapeutic System, Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Patients With Chronic Stroke.
This trial will test a promising new intervention to promote post-stroke neural reorganization and functional recovery. The overall aim is to identify a systematic, methodological approach to system fitting, training protocols…
- Trial name
- RESPARK (NCT07499310)
- Testing
- Experimental (Q Therapeutic System (BQ 3.0)
- Volunteers
- 25 people
- Sponsor
- Kessler Foundation
Stroke
Effect of Bilateral TENS With TOT on Upper Limb Function in Patients With Chronic Stroke
On the basis that the combined use of Uni-TENS and TRT is an effective intervention in upper limb recovery, and the advantage of Bi-TENS eliciting extra neural pathway in the intact hemisphere to facilitate the motor recovery…
- Trial name
- NCT03112473
- Testing
- Task-orientated training, Transcutaneous electrical nerve stimulation (TENS)
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) and Leber's hereditary optic…
- Trial name
- NCT06792500
- Testing
- Glycerol Tributyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Washington University
Chronic Stroke Patient, Motor Impairment
Multifocal Theta-Burst Stimulation to Enhance Upper Limb Motor Recovery After Stroke (INSPIRE)
Stroke is one of the leading causes of long-term disability worldwide. Many individuals who survive a stroke continue to experience weakness and reduced control of one arm, even months or years after the event.
- Conditions
- Chronic Stroke Patient, Motor Impairment, Neurorehabilitation, Theta Burst Stimulation
- Trial name
- INSPIRE (NCT07439367)
- Testing
- Active iTBS, Tablet-based upper limb training
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Stroke
Comparison of TSTVs NT Along With Conventional Therapy for Upper Limb Motor Function Among Chronic Stroke Patients
Comparison of Task Specific Training Vs Neurodevelopmental Training Along with Conventional Therapy for Upper Limb Motor Function Among Chronic Stroke Patients
- Trial name
- NCT05397366
- Testing
- Task Specific Training, Neurodevelopmental Training
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Superior University
Aphasia, Stroke
Effects of Recursive Self-feedback on Speech Production in Aphasia
The goal of this clinical trial is to test the effects of recursive self-feedback procedures on spontaneous speech production in stroke survivors with impaired speech production (aphasia).
- Trial name
- NCT06323629
- Testing
- Adaptive recursive self-feedback procedure, Non-adaptive recursive self-feedback procedure
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of South Florida
Diabetes, Hypertension
Exploring Folk Health Practices in Latinos With Chronic Medical Conditions
This study will explore how culture influences the use of folk healing practices and medical services in Latinos with chronic medical conditions.
- Conditions
- Diabetes, Hypertension, Asthma, Heart Disease
- Trial name
- NCT00224237
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Weill Medical College of Cornell University
Silent Stroke, Coronary Disease
Evaluation of Brain Damage Due to Coronary Angioplasty in Percutaneous Intervention Patients
This study examines the formation mechanism and patient-related factors of silent cerebral infarcts, whose importance has become increasingly recognized in patients undergoing percutaneous coronary intervention.
- Trial name
- NCT04734587
- Testing
- Blood serum Neuron-specific Enolase measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ondokuz Mayıs University
Chronic Stroke
Effects of Neuromuscular Electrical Stimulation on Individuals With Chronic Stroke in Patients With Chronic Stroke
Stroke is commonly associated with increased spasticity that affects patients' function and increased risk of fall. Interventional approaches have been used to decrease spasticity including pharmacological and non-pharmacological…
- Trial name
- NCT04673045
- Testing
- Active Electrical stimulation
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Qassim University
Stroke
Additional Effects of Scapular Stabilization Exercise With Exergaming Training in Stroke Patients
The World Health Organization has termed stroke to be a clinical syndrome, of presumed vascular origin, typified by rapidly developing signs of focal or global disturbance of cerebral functions and the leading cause of death…
- Trial name
- NCT05673733
- Testing
- scapular stabilization exercises with exergaming training, exergaming training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Telerehabilitation, Stroke Sequelae
Mobile App as a Guide to Exercises for Patients With Chronic Stroke
Introduction: Stroke continues to be one of the leading causes of disability in the Spanish adult population with the presentation of impairments such as alteration of mobility and a consequent reduction in quality of life.
- Conditions
- Telerehabilitation, Stroke Sequelae, Therapeutic Adherence and Compliance, Mobile Phone Use
- Trial name
- NCT04477252
- Testing
- App-core, Conventional physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Clínica de Neurorehabilitación
Stroke
Combined Effects of Tactile Kinesthetic Stimulation With Neural Mobilization in Stroke Patients
Combined Effects of Tactile -kinesthetic stimulation with Neural mobilization on sensory and motor functions of upper limb in stroke patients
- Trial name
- NCT07578961
- Testing
- Tactile kinesthetic stimulation with neural mobilization, kinesthetic therapy
- Where
- Pakistan
- Volunteers
- 53 people
- Sponsor
- Riphah International University
Gait, Hemiplegic, Quality of Life
Effect of Using a Lower Limb Robotic Device for Patients With Chronic Stroke
This study will investigate if a lower limb robotic device can be used in a community setting to increase the amount of physical activity that individuals undertake following stroke and consequently improve biomechanical…
- Conditions
- Gait, Hemiplegic, Quality of Life, Vascular Stiffness, Stroke
- Trial name
- NCT03104127
- Testing
- Alter G Bionic Leg, Normal therapy (physiotherapy)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Winchester