Clinical trials: Patients With Home Parenteral Nutrition
Catheter Related Blood Stream Infections, Intestinal Failure
Clinical Trial Comparing TaurolockTMHep100 (Taurolidine 1.35%) and 0.9% Saline As Prevention of Recurrent Catheter-related Bloodstream Infections
The purpose of the trial is to compare two catheter lock solutions (active: 1.35% taurolidine and placebo: 0.9% saline), on the occurence of catheter related blood stream infection, in patients with intestinal failure and a…
- Trial name
- NCT06660641
- Testing
- TaurolockTMHep100, 0.9 % saline
- Where
- Denmark
- Volunteers
- 61 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Patients Requiring Home Parenteral Nutrition
The HOME Study (HPN With OMEGA-3)
The aim of the trial is to investigate safety and tolerability of an Omega-3-FA-enriched lipid emulsion in adult patients with chronic intestinal failure in need of long-term HPN.
- Trial name
- HOME (NCT03282955)
- Testing
- Lipidem, Lipofundin MCT 20%
- Where
- 9 sites in France, Italy and 3 more
- Volunteers
- 74 people
- Sponsor
- B. Braun Melsungen AG
Chronic Intestinal Failure
Treatment Adherence of Home Parenteral Nutrition in Patients With Chronic Intestinal Failure. (QANPIC)
This observational, cross-sectionnal, multicentric study evaluates treatment adherence of home parenteral nutrition in patients with chronic intestinal failure.
- Trial name
- NCT05857254
- Testing
- Patient with chronic intestinal failure
- Where
- 6 sites in France
- Volunteers
- 126 people
- Sponsor
- University Hospital, Bordeaux
Vascular Access Complication
Complications Related to Vascular Access Devices in Home Parenteral Nutrition Patients
Central vascular access devices are required for home parenteral nutrition (HPN). There is few data available concerning their complications in adult HPN patients, and the potential link between venous thromboembolism and…
- Trial name
- CRVADHPNP (NCT05948514)
- Testing
- The complications related to central venous access device
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospices Civils de Lyon
Intestinal Failure, Catheter-Related Bloodstream Infection (CRBSI) Nos
Catheter Salvage in Intestinal Failure Patients
This is an observational study evaluating a catheter salvage strategy in relation to catheter-related bloodstream infections in patients with chronic intestinal failure dependent on home parenteral support.
- Trial name
- NCT03222232
- Testing
- catheter salvage
- Where
- Denmark
- Volunteers
- 715 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Crohn's Disease, Peritoneal Carcinomatosis With Intestinal Occlusion
CAre of Patients With PArenteral Nutrition At Home
This research aims to give an overview of a number of aspects related to the quality of care for adult patients on home parenteral nutrition.
- Conditions
- Crohn's Disease, Peritoneal Carcinomatosis With Intestinal Occlusion, Radiation Enteritis, Chronic Diarrhea
- Trial name
- CAPANAH (NCT01545063)
- Where
- 13 sites in Belgium
- Volunteers
- 39 people
- Sponsor
- KU Leuven
Short Bowel Syndrome
Short Bowel Syndrome and Teduglutide Versus Placebo
This research study was done to see what the effects are of Teduglutide on people with short bowel syndrome (SBS). Teduglutide is a synthetic medication administered as an injection, which has shown to increase intestinal blood…
- Trial name
- NCT02099084
- Testing
- Teduglutide
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mayo Clinic
Tumors and Home Parenteral Nutrition
Quality of Care of Oncological Patients With HPN
Medical care for patients with home parenteral nutrition (HPN) is challenging. Among other aspects, the transition from the inpatient to the outpatient setting (discharge management), the organization of HPN at home or in a care…
- Trial name
- VHPE-S (NCT03425435)
- Testing
- QoL and developed questionnaires for healthcare research
- Where
- Germany
- Volunteers
- 143 people
- Sponsor
- Fresenius Kabi
Short Bowel Syndrome
Exenatide on GI Motor Function and Permeability in Short Bowel Syndrome
We plan to examine the gastrointestinal (GI) physiologic profile of Exenatide, a glucagon-like peptide (GLP-1) analog as a possible intestino-trophic growth factor capable of inducing small bowel adaptation and regeneration in…
- Trial name
- NCT01818648
- Testing
- Exenatide
- Sponsor
- Mayo Clinic
Metastatic Gastric Cancer
Home Parenteral Nutrition for Malnourished Unresectable Stage IV Gastric Cancer
This survey is a single arm study to assess the effect of home parenteral nutrition on overall survival, cycles of salvage chemotherapy completed, side effects of salvage chemotherapy, quality of life, nutritional status…
- Trial name
- NCT03121807
- Testing
- Oliclinomel N4 Per bag 1.5 L, Oxaliplatin, 5Fluorouracil
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Sepsis
Effect of Taurolidin on Prevention of Bloodstream Infection
Home parenteral nutrition (HPN) is a validated technique for patients with various intestinal disease leading to chronic malabsorption or obstruction, whatever the aetiology.
- Trial name
- Nutrilock (NCT00545831)
- Testing
- Taurolidine, Physiologic Serum
- Where
- 7 sites in France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Rouen
Catheter Related Blood Stream Infections
Clinical Trial With Catheter Locking TauroSept® (Taurolidine 2%) or Saline Solution 0,9%
The purpose of this study is to determine if TauroSept® taurolidine 2% is more efficient than saline solution 0.9% as a catheter lock solution in preventing catheter related blood stream infections in patients with home…
- Trial name
- NCT01826526
- Testing
- TauroSept®
- Where
- 7 sites in Denmark, Germany and 4 more
- Volunteers
- 105 people
- Sponsor
- Geert Wanten
Patients With Home Parenteral Nutrition
Chronobiology and Home Parenteral Nutrition Study. CHRONO-HPN Study
Medical Nutritional Therapy (MNT) is critical for patients with impaired oral intake and is typically administered via parenteral nutrition (PN).
- Trial name
- NCT07554703
- Testing
- Patient recieving home parenteral nutrition
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Parenteral Nutrition
Crossover Study on the Effect of Omegaven in Combination With Different Lipid Emulsions in Home Parenteral Nutrition
The aim of this study was to evaluate the safety and tolerance of ClinOleic or Lipoplus or SMOFlipid lipid emulsions. After 6 weeks of each lipid emulsion, Omegaven (fish oil) was added for a further 4 weeks.
- Trial name
- NCT03149653
- Testing
- ClinOleic (baseline), ClinOleic + Omegaven, Lipoplus (baseline)
- Where
- Czechia
- Volunteers
- 24 people
- Sponsor
- General University Hospital, Prague
Catheter-related Bloodstream Infection (CRBSI) Nos
Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml.
The purpose of the investigation is to compare two catheter lock solutions (TaurolockTMHep100 and Heparin 100 IE/ml), on the occurence of catheter related blood stream infection, in patients with intestinal failure and a central…
- Trial name
- NCT01948245
- Testing
- TaurolockTMHep100, Heparin 100 IE/ml
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Palle Bekker Jeppesen
Chronic Intestinal Failure, Intestinal Failure
Anabolic Response To Intravenous Amino Acids In Chronic Intestinal Failure Patients
The purpose of this study is to gain insight into the actual protein requirements of patients with chronic intestinal failure (CIF) receiving home parenteral nutrition, which could improve clinical management of these patients.
- Conditions
- Chronic Intestinal Failure, Intestinal Failure, Home Parenteral Nutrition
- Trial name
- NCT07422792
- Testing
- Intravenous Amino Acids
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- Institute of Oncology Ljubljana