Clinical trials: Patients With Rectal Cancer
Colorectal Neoplasms
Risk-adapted Screening in First-degree Relatives of Patients With Colorectal Cancer
BACKGROUND: First-degree relatives of patients with colorectal cancer are at increased risk for colorectal cancer as well. Nevertheless, participation in the German national screening program stagnates at 2-3 percent per year…
- Trial name
- FAMKOL (NCT01903395)
- Testing
- Nurse-led counselling
- Where
- 33 sites in Germany
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Colorectal Cancer
Brief Self-Compassion Program in Colorectal Cancer
In this study, between 1 December 2024-31 March 2025, who met the inclusion and exclusion criteria, a total of 66 patients with colorectal cancer at the Etlik City Hospital General Surgery Department.
- Trial name
- NCT06707337
- Testing
- Brief Self-compassion Program
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kübra DAKDEVİR
Breast Cancer, Colorectal Cancer
Family Quality of Life Among Families With a Member Who is a Cancer Patient
RATIONALE: Developing a questionnaire that can be used to assess the quality of life among people who have a family member with cancer may help the study of cancer in the future.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00544336
- Testing
- questionnaire administration, survey administration, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Breast Cancer, Colorectal Cancer
Nurse-led Proactive Telephone Follow-up With Patients After Completion of Primary Cancer Treatment
The goal of this randomized study is to test and evaluate nurse-led telephone follow-up intervention in patients primarily curatively treated for breast cancer, colorectal cancer, and prostate cancer.
- Conditions
- Breast Cancer, Colorectal Cancer, Prostate Cancer
- Trial name
- NCT06223022
- Testing
- Proactive nurse-led telephone follow-up
- Where
- Sweden
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Umeå University
Gastrointestinal Cancer, Rectal Cancer
A Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Weekly Procrit Given to Gastric or Rectal Patients
To demonstrate the effectiveness of epoetin alfa on reduction in red blood cell transfusions in gastric and rectal cancer patients undergoing preoperative chemoradiation therapy followed by surgery.
- Trial name
- NCT00254436
- Testing
- Procrit (epoetin alfa)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Neoplastic Cells, Circulating
The Detection of Circulating Tumor Cells (CTCs) in Patients With Colorectal Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Circulating tumor cells (CTCs) have the potential to provide a surrogate for'real-time biopsy' of tumor biological activity. Enumeration and molecular characterization of CTCs in colorectal cancer could play an important role in…
- Trial name
- NCT02450422
- Testing
- Flow cytometry (FCM), RT-PCR
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Colorectal Neoplasms
Characteristics of Gut Microbiota in Patients With Colon Cancer of Different Traditional Chinese Medicine Syndromes
Guided by the idea of combining disease differentiation with syndrome differentiation in traditional Chinese medicine, this study used the form of questionnaire to summarize the changes of TCM syndromes, TCM constitution types in…
- Trial name
- NCT03892252
- Testing
- No intervention
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Wei Xu
Colon Cancer
The Efficiency of Colon Capsule Endoscopy in Colon Cancer Screening
Main objective is to improve colorectal cancer (CRC) screening programme in the Czech Republic and decrease the disease incidence and mortality.
- Trial name
- NCT03052335
- Testing
- Pillcam® COLON 2 Capsule, Colonoscopy
- Where
- Czechia
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Military University Hospital, Prague
Rectal Cancer, Gut Microbiomes
Autologous Probiotics in Patients With Defunctioning Ileostomy Following LAR for Rectal Cancer
Rectal cancer patients who received low anterior resection combined with ileostomy may effectively reduce the probability of anastomotic leakage after surgery.
- Conditions
- Rectal Cancer, Gut Microbiomes, Autologous Probiotic Transplantation, Defunctioning Ileostomy
- Trial name
- NCT07366047
- Testing
- Autologous Probiotics
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Liver Cancer, Esophageal Cancer
Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease…
- Conditions
- Liver Cancer, Esophageal Cancer, Colorectal Cancer, Lung Adenocarcinoma
- Trial name
- TEG (NCT05517811)
- Testing
- TEG indices
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Bladder Cancer, Glioma
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
The objective of this study is to assess two novel positron emission tomography (PET) radiotracers, [64Cu]CM500 and [68Ga]CM500, for Positron Emission Tomography-Magnetic Resonance Imaging (PET-MR) and Positron Emission…
- Conditions
- Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer
- Trial name
- NCT07781852
- Testing
- [64Cu]CM500, [68Ga]CM500, PET/MR
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lumina Pharmaceuticals Inc
Colorectal Cancer (CRC)
Fecal Immunochemical Test in Diagnosing Colorectal Cancer Among Vietnamese Patients with Lower Gastrointestinal Symptoms
The goal of this clinical trial is to evaluate the diagnostic value of fecal immunochemical tests (FIT) in identifying colorectal cancer (CRC) among Vietnamese individuals presenting with lower gastrointestinal symptoms.
- Trial name
- NCT06776120
- Testing
- Fecal chemical test (FIT)
- Where
- Vietnam
- Volunteers
- 1,575 people, healthy volunteers welcome
- Sponsor
- Luu Ngoc Mai
HPV-Related Carcinoma, HPV Infection
Determining the Frequency of Occurrence and Defining the Most Appropriate Screening Test for Anal Intraepithelial Neoplasia (AIN) in Patients With Human Papillomavirus (HPV) Related Gynecological Diseases.
The primary aim of the study is to determine the total risk of AIN in group of HPV-RGD survivors and additionally to establish an exact risk for each of HPV-related gynecological precancers/cancers.
- Trial name
- NCT06574087
- Testing
- hrHPV test and cytology
- Where
- Poland
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- PCK Marine Hospital in Gdynia
Metastatic Colorectal Carcinoma
Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer
The aim of this work is to assess the antitumor effect of Pentoxiphylline in patients with metastatic colorectal cancer receiving stomatal chemotherapy ± targeted therapy.
- Trial name
- CRC - PTX (NCT06115174)
- Testing
- Pentoxifylline, FOLFOX, XELOX
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tanta University
Patient Empowerment, Low Anterior Resection Syndrome
Interactive Online Informational and Peer Support App for Patients with Low Anterior Resection Syndrome
After surgery for rectal cancer, many people undergo changes in bowel habits, which may include the need to empty their bowels more often, accidental leakage of stool or gas, the sudden urge to go to the bathroom, and more.
- Conditions
- Patient Empowerment, Low Anterior Resection Syndrome, Colo-rectal Cancer, Peer Group
- Trial name
- NCT04469426
- Testing
- Interactive online informational and peer support app
- Where
- 5 sites in Canada
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Colon Cancer, Rectum Cancer
Evaluating Factors Affecting Survival in Colon and Rectum Cancer
Colorectal cancers are frequent among cancers of the gastrointestinal system. Whether there are any differences between survival in rectum and colon cancer patients is controversial.
- Trial name
- NCT05388513
- Testing
- Surgical Resection
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Diet, Healthy, Colorectal Cancer
Introducing a Plant-Based Diet for Patients With Colorectal Diseases
Dietary patterns are a potentially modifiable risk factor for colon cancer recurrence, flares in inflammatory bowel diseases, and for chronic diseases. Nutritional counseling is rarely brought up during medical appointment.
- Trial name
- NCT05526846
- Testing
- Plant-based diet education
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colorectal Cancer
The Role of Coenzyme Q10 in the Prophylaxis of Oxaliplatin Induced Peripheral Neuropathy in Patients With Colorectal Cancer
This study aims to evaluate the possible beneficial role of coenzyme Q10 against oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.
- Trial name
- NCT06856447
- Testing
- Coenzyme Q10, Oxaliplatin, 5-Fluorouracil (5-FU)
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- toqa saad mohammed mohammed
Gastrointestinal Disease, Colorectal Cancer
Randomized Controlled Study Comparing Colon Evaluation With The Pure-Vu System To A Standard Colonoscopy In Patients Who Are High Risk For Inadequate Bowel Preparation
The primary objective of this multi-center, prospective, randomized controlled trial is to evaluate the bowel cleansing after Pure-Vu use in outpatient subjects at high risk for inadequate colon preparation as compare to standard…
- Trial name
- RESCue (NCT04285008)
- Testing
- Pure-Vu System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Patient Empowerment, Patient Activation
Educational Nursing Intervention Among Patients With Colorectal Cancer During Chemotherapy
The prevalence of malnutrition is common among patients with colorectal cancer. Chemotherapy induced side effects may impact negatively on nutrition intake thus increase the risk of malnutrition and serious complications for…
- Conditions
- Patient Empowerment, Patient Activation, Self Care, Cancer of Colon
- Trial name
- NCT04160650
- Testing
- Educational nursing intervention on nutrition intake related chemotherapy induced side-effects' self-care among the patients with colorectal cancer
- Where
- Finland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Turku