Clinical trials: Patients With Speech Disorders
Auditory Processing Disorder, Central, Stroke
Auditory Rehabilitation in Stroke Patients With Auditory Processing Disorders
This study aimed to evaluate long term benefits in speech reception in noise, after daily 10 week use of an assisting listening device (personal frequency-modulates systems) , in non-aphasic stroke patients with auditory…
- Trial name
- NCT02889107
- Testing
- personal frequency modulated systems
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University College, London
Aphasia, Stroke
tDCS Effects on Brain Plasticity in Aphasia Treatment
The efficacy of conventional speech therapy alone for aphasia recovery is inconclusive. The prospective study will monitor the effects of combined language therapy and tDCS through structural and functional MRI.
- Trial name
- NCT05483556
- Testing
- Real tDCS
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The Hong Kong Polytechnic University
Post-stroke Aphasia, PSA
Effectiveness of Electroacupuncture at Xuanzhong (GB39) and Tongli (HT5) Points in Post-Stroke Aphasia
Post-stroke aphasia (PSA) is a prevalent and debilitating condition that significantly impairs communication, social participation, and quality of life, often leading to increased long-term healthcare costs and psychological…
- Trial name
- NCT07684781
- Testing
- Electroacupuncture, Basic treatment + Speech therapy
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis)
Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS
This study evaluates potential of music therapy treatment to support breathing, speech, swallow and cough of persons with amyotrophic lateral sclerosis (ALS).
- Conditions
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis), Dysarthria, Flaccid, Dysarthria, Spastic
- Trial name
- NCT03604822
- Testing
- Music therapy
- Where
- 2 sites in Russia, United Kingdom
- Volunteers
- 8 people
- Sponsor
- Alisa Apreleva
Hearing Loss, Cochlear
Benefits From Bimodal Fittings With Cochlear Implant and Hearing Aid vs Bilateral Hearing Aids
Hearing-aid (HA) users with insufficient HA may be better helped with a "Bimodal solution" when replacing the HA with a Cochlear implant (CI) to the poorer hearing ear and a HA to the better hearing ear.
- Trial name
- NCT04919928
- Testing
- Cochlear Implant and Hearing aid in bimodal solution, Bilateral hearing aids
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Edentulous Jaw
The Effect of Implant-supported Prosthesis on Acoustic Voice Quality
The primary aim of this study was to compare the acoustic sound quality of edentulous patients rehabilitated with two-implant overdentures or the all-on-4 concept.
- Trial name
- NCT05692609
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Sleep Apnea, Obstructive, Hypertension Secondary
Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome
The purpose of this study is to analyze the effect of speech therapy on quality of life, sleep quality, daytime sleepiness level and apnea-hypopnea index in patients with hypertensive patients with mild obstructive apnea syndrome.
- Trial name
- NCT03753633
- Testing
- Speech therapy, Control
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Nonfluent Variant Primary Progressive Aphasia (nfvPPA)
Clinical Study of Neflamapimod in Patients With Primary Progressive Aphasia
The goal of this exploratory study is to evaluate the effect of neflamapimod in participants with nonfluent variant primary progressive aphasia (nfvPPA).
- Trial name
- NCT07033481
- Testing
- Neflamapimod
- Where
- 7 sites in United States, United Kingdom
- Volunteers
- 20 people
- Sponsor
- EIP Pharma Inc
Aphasia
Learning to Communicate Successfully Approach for Urdu Speaking Patients With Chronic Aphasia
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA), a culturally sensitive communication intervention manual for Urdu-speaking adults with chronic aphasia.
- Trial name
- LCSA (NCT07889778)
- Testing
- Learning to Communicate Successfully Approach (LCSA)
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
GERD
Pre- and Post-Therapy Evaluation of Air-Associated Symptoms in Patients With Gastro-esophageal Reflux Disease (GERD): Assessing the Role of Speech and Language Therapy
Patients with gastroesophageal reflux disease (GERD) may present with concomitant gas-related symptom (GRS) such as supragastric or gastric belching, and aerophagia.
- Trial name
- LAS (NCT07634614)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Prof Urs Zingg
Sensorineural Hearing Loss, Bilateral
Speech Perception of a Tonotopy-based Fitting for Cochlear Implant Recipients for 6 Months With Conventional Setting
Main objective: Compare speech recognition in noise with tonotopic fitting (FS4T) and with conventional non-tonotopic fitting (FS4noT) in adult patients implanted for 6 months with a MED-EL cochlear implant with FS4noT strategy.
- Trial name
- NCT06723262
- Testing
- Tonotopic cochlear implant fitting FS4T
- Where
- France
- Volunteers
- 25 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Frontotemporal Dementia, Dementia
Dopaminergic Therapy for Frontotemporal Dementia Patients
This is a phase IIa 24-week randomized, double-blind, placebo-controlled study. The study is designed to evaluate the efficacy and safety of Rotigotine (RTG) transdermal administration at the dosage of 4 mg or 6 mg per day versus…
- Conditions
- Frontotemporal Dementia, Dementia, Aphasia, Primary Progressive, Pick Disease of the Brain
- Trial name
- NCT04937452
- Testing
- Rotigotine 4Mg/24Hrs Patch, Rotigotine 6Mg/24Hrs Patch
- Where
- 3 sites in Italy
- Volunteers
- 75 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Aphasia
Effect of Stimulation of the Prefrontal Cortex on Language Production in Aphasic Patients
The purpose of this study is to investigate whether transcranial direct current stimulation (tDCS) of the prefrontal cortex (PFC) influences lexical access and language production.
- Trial name
- NCT02840370
- Testing
- transcranial direct current stimulation
- Where
- 3 sites in Switzerland
- Volunteers
- 19 people
- Sponsor
- Jean-Marie Annoni
Dysphagia, Oropharyngeal, Stroke, Ischemic
Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke
This study will evaluate the effectiveness of conventional speech therapy associated with functional electrical stimulation in patients with dysphagia after ischemic stroke.
- Trial name
- NCT03649295
- Testing
- Functional Electrical Stimulation, Conventional Speech Therapy
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Hospital Geral de Fortaleza
Hearing Loss
Electrophysiological Study of Interindividual Differences in Speech-understanding Among Cochlear Implant Patients
Differences in speech-understanding and the quality of the subjective perception among cochlear implant patients (Digisonic SP) depends on numerous factors.
- Trial name
- NCT01805167
- Testing
- Electrophysiological study of the interindividual variability of vocal performance
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Mild Cognitive Impairment (MCI) Amnestic, Parkinson Disease (PD)
Early Stage of Alzheimer's and Parkinson's Diseases, HearIng Relevance (SAPHIR)
The study aims to phenotype hearing in patients with early stage of neurodegenerative disorders to explore the prevalence of various hearing disorders in comparison to a control population.
- Conditions
- Mild Cognitive Impairment (MCI) Amnestic, Parkinson Disease (PD), Healthy Participants
- Trial name
- SAPHIR (NCT07083089)
- Testing
- Thorough Hearing assessment
- Where
- 4 sites in France
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Cilcare SAS
Stroke, Aphasia
Effects of rTMS Based on Neural Activation in Language Performance in Stroke Patients With Non-fluent Aphasia
The aim of this study is to assess the safety and clinical efficacy of repetitive transcranial magnetic stimulation (rTMS) based on hemodynamic brain activity pattern with functional near infrared spectroscopy (fNIRS) in early…
- Trial name
- NCT02591719
- Testing
- MagPro magnetic stimulator (HF rTMS), MagPro magnetic stimulator (LF rTMS)
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Seoul National University Bundang Hospital
Unilateral Vocal Cord Paralysis
Non-phonatory Exercises in Patients with Unilateral Vocal Fold Paralysis Post-thyroidectomy
Thyroidectomy is the most common iatrogenic cause of vocal fold paralysis. Patients complain of hoarseness caused by incomplete glottic closure and have effort to raise vocal intensity with consequent elevation of the larynx…
- Trial name
- ENFP (NCT05963165)
- Testing
- Non-phonatory exercises
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Aphasia
The Usage of High-resolution Magnetic Resonance Imaging in Patients With Post-stroke Aphasia for Predicting the Outcome
Combined analysis of functional and structural language network changes may be a good model for predicting language outcome.
- Trial name
- NCT03475745
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Aphasia
Effect of Music on Reading Comprehension in Patients With Aphasia
The purpose of this investigation is to examine the evidence on emotion, language, and music, and propose a first step, in the form of a single-subject research design, to determine the most effective and efficient method for…
- Trial name
- NCT03600987
- Testing
- Simultaneous music and reading lyrics, Priming with music, Control
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Carilion Clinic