Clinical trials: Patients With Total Knee Arthroplasty
Osteo Arthritis Knee, Knee Arthroplasty
Physiotherapy and Therapeutic Education on Patients With Pain Catastrophism Scheduled for a Total Knee Arthroplasty
The purpose of this study is to test whether adding a treatment using pain neuroscience education (PNE) and multimodal physiotherapy to usual care, in subjects with knee osteoarthritis and pain catastrophizing, who are scheduled…
- Conditions
- Osteo Arthritis Knee, Knee Arthroplasty, Catastrophizing, Pain
- Trial name
- NCT03847324
- Testing
- Pain Neuroscience Education, Multimodal Physiotherapy, Usual Care
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Barcelona
Mobility After Total Knee Arthroplasty
Adductor Canal Blockade vs Femoral Nerve Blockade on Muscle Strength, Mobility and Pain After TKA
The purpose of the study is to compare the effect of a Adductor Canal Blockade (ACB) vs a Femoral Nerve Blockade (FNB), on muscle strength, mobility and pain in patients with severe pain (VAS pain score > 60) after Total Knee…
- Trial name
- NCT01922596
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Knee Surgeries, Total Ankle Arthroplasty
Adductor Canal Block With IPACK Versus 4-in-1 Block for Postoperative Analgesia in Knee Surgery
This randomized interventional study compares the analgesic efficacy of Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) versus the 4-in-1 block technique in patients undergoing knee…
- Conditions
- Knee Surgeries, Total Ankle Arthroplasty, Anterior Cruciate Ligament (ACL) Tear, Posterior Cruciate Ligament Tear
- Trial name
- NCT07700797
- Testing
- Adductor canal block with IPACK, 4 in 1 block
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Osteo Arthritis Knee, Central Nervous System Sensitization
Pregabalin for Central Sensitization in TKA
The study purpose is to determine if giving pregabalin before and after total knee arthroplasty (TKA) can improve pain and meaningful function after surgery in patients that have central sensitization (CS).
- Trial name
- NCT05460871
- Testing
- Pregabalin 75mg
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Knee Disease
Study Conducted on Patients Operated With a FHK ASYMETRIQUE to Confirm Security and Performance of the Device
This study is a post-market clinical follow-up conducted in order to collect long-term data on security and performance of the FHK asymetrique prosthesis, which is intended to be implanted in case of total knee replacement, when…
- Trial name
- NCT04221581
- Testing
- Knee prosthesis - FHK ASYMETRIQUE total knee prosthesis
- Where
- 3 sites in France
- Volunteers
- 43 people
- Sponsor
- FH ORTHO
Knee Osteoarthritis, Arthroplasty, Knee Replacement
Comparison of High Intensity Strength Training and Muscle Energy Techniques in TKR Patients
Globally, the prevalence of total joint replacement (TKR) procedures has been rising, providing patients with better joint function, decreased pain, and enhanced quality of life.
- Conditions
- Knee Osteoarthritis, Arthroplasty, Knee Replacement, Resistance Training
- Trial name
- NCT06407778
- Testing
- High Intensity Strength Training, Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Orthopedic Disorder
Effect of Preoperative Education Based on Roy Adaptation Model
This research was conducted as a randomized controlled experiment to determine the effect of the education given by the Physiological Mode of Roy Adaptation Model in patients with hip or knee arthroplasty on physical adaptation…
- Trial name
- NCT05248529
- Testing
- Education booklet
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Elderly, Knee Arthroplasty
Dexmedetomidine Combined With Ropivacaine for Postoperative Continuous Femoral Nerve Block
Delirium is common in the elderly after orthopedic surgery and is associated with worse outcomes. Continuous femoral nerve block is frequently used for postoperative analgesia after total knee arthoplasty.
- Conditions
- Elderly, Knee Arthroplasty, Nerve Block, Dexmedetomidine
- Trial name
- NCT03629483
- Testing
- Dexmedetomidine
- Volunteers
- 3 people
- Sponsor
- Peking University First Hospital
Arthroplasty, Replacement, Knee
Postoperative Hypothermia Control In Older Patients With Total Knee Arthroplasty: Effect Of Electric And Woolen Blanket
The purpose of this studywas to assess as experimental whether if electric blanket together withwoolen blanketwere effective in the postoperative period at patients with TKA.
- Trial name
- NCT05389579
- Testing
- electric blanket
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Esra Demirarslan
Posterior Knee Infiltration
Posterior Capsular Injection With Femoral Nerve Block for Total Knee Arthroplasty
To assess pain control after total knee replacement surgery using two different nerve block techniques. The 2 methods are: 1. Continuous femoral nerve block with ultrasound guided posterior capsular injection 2.
- Trial name
- NCT02701296
- Testing
- Ropivacaine with Epinephrine, Ropivacaine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Trinity Health Of New England
Obesity, Aseptic Loosening
Analysis of Varus Collapse in Obese Patients With Stem and Non-Stem Tibial Components Following Primary Total Knee Arthroplasty
The purpose of this study is to compare rates of varus collapse, aseptic loosening, and implant failure in female obese patients undergoing total knee arthroplasty (TKA) and will review the degree of influence of stemmed tibial…
- Conditions
- Obesity, Aseptic Loosening, Varus Collapse
- Trial name
- SvNS (NCT06019832)
- Testing
- Total Knee Arthroplasty (TKA), Stemmed Tibial Implant, Non-stemmed tibial implant
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Jacob M. Elkins
Arthrosis
Topical Versus Intravenous Tranexamic Acid in Total Knee Arthroplasty
This clinical trial investigated two different routes of administration of tranexamic acid in total knee arthroplasty: topical compared to intravenous.
- Trial name
- TRANEXTKA (NCT02323373)
- Testing
- Tranexamic Acid - topical, Tranexamic Acid - intravenous
- Volunteers
- 90 people
- Sponsor
- Irmandade da Santa Casa de Misericordia de Sao Paulo
Total Knee Arthroplasty
A Prospective Clinical Study Evaluating the Newton™ TKA Protocol
Evaluation of clinical outcomes and patient recovery in patients receiving TKA with traditional instrumentation systems compared to full arc of motion gap balancing using the Newton TM Knee Protocol
- Trial name
- NCT06678750
- Testing
- TKA using computer navigation, TKA
- Where
- United States
- Sponsor
- Newton-Wellesley Hospital
Total Knee Arthroplasty
Reliability, Concurrent Validity and Minimal Detectable Change of the Step Up and Down Test in Patients With Total Knee Arthroplasty
The aim of the study is to measure the validity and reliability of the StUD test in patients with TKA. Forty-seven patients with primary TKA included in this study.
- Trial name
- NCT06344182
- Testing
- Step Up and Down Test
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Dokuz Eylul University
Knee Osteoarthritis, Degenerative Joint Disease of the Knee
Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomized Insert Types
This study aims to evaluate patient outcomes following robotic-assisted total knee arthroplasty using the VELYS system. Patients undergoing surgery will receive either kinematic alignment or functional alignment as determined by…
- Trial name
- VELYS RCT (NCT07533188)
- Testing
- Medial Stabilized Insert, Cruciate Retaining Insert
- Where
- Singapore
- Volunteers
- 240 people
- Sponsor
- Singapore General Hospital
Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain
Postoperative Pain and Analgesic Use After Total Knee Arthroplasty
This prospective observational study evaluates postoperative pain intensity and analgesic consumption in patients undergoing total knee arthroplasty (TKA) under different anesthesia techniques.
- Conditions
- Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain, Analgesic Consumption
- Trial name
- NCT07457814
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Total Knee Arthroplasty
Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)
The purpose of this study is to find a better way to make patients comfortable after their knee surgery. The investigators compared three ways of providing pain relief, either by use of a nerve block at the femoral and sciatic…
- Trial name
- NCT02223364
- Testing
- Peripheral nerve blocks with Bupivacaine, Intra articular injection with Ropivacaine, Intra articular injection with liposomal bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Primary Knee Replacement
iAssist vs. Conventional Instrumentation in Total Knee Arthroplasty Using the Persona Knee System Among Patients With BMI>=30: Radiographic, Clinical and Economic Outcomes
The purpose of this prospective randomized study is to evaluate iAssist with respect to radiographic, clinical and economic outcomes in comparison to conventional instrumentation in primary total knee arthroplasty using the…
- Trial name
- NCT02117973
- Testing
- iAssist Technique using Persona system vs. the conventional technique using Persona system
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Predicting Outcome of Total Knee Replacement Surgery in Patients With Knee Osteoarthritis
Osteoarthritis (OA) is the main cause of pain and disability in elderly. For knee OA, a total knee replacement (TKR) is an effective surgical treatment, and the majority of patients report substantial pain relief and functional…
- Trial name
- NCT05380648
- Testing
- Total knee arthroplasty
- Where
- Belgium
- Volunteers
- 223 people
- Sponsor
- Universiteit Antwerpen
Knee Arthritis
Knee Arthroplasty Performed With Conventional and Customized Instrumentation
The main purpose of this study is to determine whether the surgical time required for primary total knee arthroplasty is significantly less when performed with Customized Patient Instrumentation (CPI) than with conventional…
- Trial name
- CPI (NCT01124305)
- Testing
- Customized Patient Instrumentation, Traditional Instrumentation
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Anderson Orthopaedic Research Institute