Clinical trials: Patients with Multiple Sclerosis
Multiple Sclerosis
Noninterventional Study Assessing Cognitive Function and Physical Activity in People With Multiple Sclerosis
Study assessing cognitive function and physical activity in people with relapsing remitting multiple sclerosis.
- Trial name
- CogniPlus (NCT01491100)
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046)
- Where
- 17 sites in Albania, Algeria and 15 more
- Volunteers
- 1,085 people
- Sponsor
- Bayer
Multiple Sclerosis
An International, Multicenter, Randomized, Double-Blind, Double-Masked Study of the Efficacy and Safety of BCD-132 (JSC BIOCAD, Russia) Using an Active Reference Drug (Teriflunomide) for the Treatment of Patients With Multiple Sclerosis
Clinical study BCD-132-4/MIRANTIBUS is an international, multicenter, randomized, double-blind, double-masked study using an active reference drug (teriflunomide).
- Trial name
- MIRANTIBUS (NCT05385744)
- Testing
- BCD-132, Teriflunomide
- Where
- Russia
- Volunteers
- 336 people
- Sponsor
- Biocad
Multiple Sclerosis
Quantifying Gait Alteration in Multiple Sclerosis Using a Wearable Device
Gait alteration is frequent in MS and limitation in walking ability is a major concern in MS patients. The development of wearable device offers the opportunity to collect data during daily activity including walking.
- Trial name
- eMSGait (NCT04969848)
- Testing
- Wearable sensor
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Nantes University Hospital
Multiple Sclerosis
Study of Ovarian Reserve Concerning Patients With Multiple Sclerosis (MS), Compared to a Control Group
The investigators want to evaluate ovarian reserve concerning patients with multiple sclerosis, compared to a control group of healthy women. This study will include women from 25 to 35 years old.
- Trial name
- FEMINISEP (NCT05754593)
- Testing
- Anti-Mullerian hormone (AMH) level, Antral follicle count (AFC), Clinical assessment
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Traumatic Brain Injury, Stroke
Remote Neuropsychological Assessment of Patients With Neurological Disorders and Injuries
For the last decades, many aspects of human life have been altered by digital technology. For health care, this have opened a possibility for patients who have difficulties travelling a long distance to a hospital to meet with…
- Conditions
- Traumatic Brain Injury, Stroke, Multiple Sclerosis, Parkinson Disease
- Trial name
- NCT05819008
- Testing
- Neuropsychological Assessment
- Where
- Sweden
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Umeå University
Multiple Sclerosis
The Reliability and Validity of the L-test in Patients With Multiple Sclerosis
Walking safely inside or outside is an important function in patients with Multiple Sclerosis (PwMS) that affects their daily life activity and participation.
- Trial name
- NCT05641714
- Testing
- L test, Timed Up and Go test, 10 meter walk test
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Gazi University
Multiple Sclerosis
Open Label Study to Evaluate Effect, Safety and Tolerability of Betaferon Standard Dose of 250µg in Patients of Chinese Origin With Multiple Sclerosis
The purpose of this study is to determine if the study drug is effective and safe in the treatment of Multiple Sclerosis (MS) in patients of Chinese origin.
- Trial name
- NCT00370071
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046)
- Where
- 3 sites in China
- Volunteers
- 39 people
- Sponsor
- Bayer
Multiple Sclerosis
Correlation Between the 'Nine Holes Peg Test' Performance and the Triple Stimulation Technique Within a Group a Patients With Multiple Sclerosis
The main goal of this study is to determine if the Triple Stimulation Technique (TST) can be correlated to performance in the manual dexterity 'nine holes peg' test, within a control group and a group of patients with multiple…
- Trial name
- NCT02805634
- Testing
- Nine Hole Test, Triple Stimulation Technique
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Multiple Sclerosis
Famciclovir in Multiple Sclerosis
This is a proof-of-concept study in 30 patients with established Relapsing Remitting Multiple Sclerosis (RRMS). IMP is Famciclovir. It is a phase II type A open label study.
- Trial name
- NCT05283551
- Testing
- Famciclovir
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Queen Mary University of London
Multiple Sclerosis, Physical Disability
Measuring Consequences of Disability for Patients With Multiple Sclerosis and Caregivers on Economic Burden
The objective of this study is to measure economic burden of Multiple Sclerosis (MS) from a new point of view that includes consequences of disability on Quality Of Life (QOL), social participation and capabilities of patients…
- Conditions
- Multiple Sclerosis, Physical Disability, Economic Burden, Social Interaction
- Trial name
- ECOPASEP (NCT02592265)
- Volunteers
- 233 people
- Sponsor
- Lille Catholic University
Patients With Multiple Sclerosis
Clinical Correlates of Psychiatric Comorbidities in Patients With Multiple Sclerosis
Many neuropsychiatric abnormalities associated with multiple sclerosis (MS). These may be broadly divided into 2 categories: disorders of mood, affect,and behavior and abnormalities affecting cognition.
- Trial name
- NCT05382195
- Testing
- hospital anxiety and depression scale
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Multiple Sclerosis
Safety and Efficacy of Intrathecal Rituximab in Patients With Multiple Sclerosis
Considering the accumulated data on the pathogenesis of multiple sclerosis, indicating a significant role of B cells in the progression of the disease, the use of monoclonal antibodies to CD20 antigen, administered intrathecally…
- Trial name
- NCT05078177
- Testing
- Rituximab
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Multiple Sclerosis, Intestinal Dysfunction
Characteristics of INTESTINAL DYSFUNCTION in Patients With MULTIPLE SCLEROSIS
MS (Multiple Sclerosis) is the most common neurological disease involving disabilities in young adults, with bowel symptoms, in particular constipation and fecal incontinence.
- Conditions
- Multiple Sclerosis, Intestinal Dysfunction, Anal Incontinence, Microbiota
- Trial name
- NCT04599595
- Testing
- Peristeen (Coloplast)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University Hospital of Ferrara
Multiple Sclerosis, Exercise
Impact of Exercise Training on Serum Neurofilament Light Chain (NfL), Brain Volumetry, and Functional Outcomes in Multiple Sclerosis
This single-blind, randomized controlled trial will employ a two-arm parallel design (exercise group vs. control group) with a 12-week intervention period.
- Conditions
- Multiple Sclerosis, Exercise, Neurofilament Light Chain
- Trial name
- NCT07520812
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Firat University
Multiple Sclerosis, Cognitive Decline
Computerized Cognitive Training in MS
WHO: 40 participants with a confirmed diagnosis of Multiple Sclerosis (MS) able to engage in moderate physical activity. WHY: The purpose of this study is to evaluate two computerized brain training tools, which include light…
- Trial name
- NCT03737825
- Testing
- Computerized gaming rehabilitation Program 1, Computerized gaming rehabilitation Program 2
- Where
- 2 sites in United States, Switzerland
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Multiple Sclerosis
A Study to Evaluate the Safety, Tolerability and Efficacy of AIN457 in Patients With Relapsing-remitting Multiple Sclerosis
The study will assess the long-term safety and tolerability of AIN457 in patients with relapsing-remitting multiple sclerosis (RRMS).
- Trial name
- NCT01433250
- Testing
- AIN457
- Where
- 14 sites in Czechia, Russia and 1 more
- Volunteers
- 39 people
- Sponsor
- Novartis Pharmaceuticals
Spasticity Due to Multiple Sclerosis
BX-1 in Spasticity Due to Multiple Sclerosis
To investigate the efficacy and safety of orally administered BX-1 compared to placebo in patients with spasticity due to multiple sclerosis not sufficiently controlled by current anti-spasticity medication
- Trial name
- NCT03756974
- Testing
- BX-1
- Where
- 40 sites in Czechia, Germany and 3 more
- Volunteers
- 397 people
- Sponsor
- Bionorica SE
Multiple Sclerosis, Mood Disorders
Study of Brain Activations and Physiological Responses Using NeuroBiofeedback in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by inflammation, demyelination, gliosis, and neuronal loss.
- Conditions
- Multiple Sclerosis, Mood Disorders, Cognitive Impairment
- Trial name
- NBF2023 (NCT06239090)
- Testing
- Rehacor-T
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Multiple Sclerosis
Novel Immune Markers in Patients With Multiple Sclerosis
The investigators hypothesize that the endogenous cannabinoid signalling system has lost homeostasis in the disease multiple sclerosis (MS).
- Trial name
- NIMMS (NCT01026272)
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Washington
Tuberous Sclerosis Complex
Predicting Epileptogenic Tubers in Patients with Tuberous Sclerosis Complex
Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging because ETs lack distinct pathological or genetic markers that differentiate them from other…
- Trial name
- NCT06789419
- Volunteers
- 112 people
- Sponsor
- Beijing Children's Hospital
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