Clinical trials: Patients with Multiple Sclerosis
Secondary Progressive Multiple Sclerosis
A Study for Patients With Multiple Sclerosis
To obtain additional safety data in subjects who have previously completed the MBP8298-01 study "A Double Blind Placebo Controlled Multi-Centre to Evaluate the Efficacy and Safety of MBP8298 in Subjects with Secondary Multiple…
- Trial name
- MAESTRO-02 (NCT00870155)
- Testing
- dirucotide
- Where
- 10 sites in Canada, Denmark and 8 more
- Volunteers
- 546 people
- Sponsor
- Eli Lilly and Company
Multiple Sclerosis, Relapsing-Remitting
Assessment of Deep Gray Matter Anatomic Changes in RRMS Patients Treated With Gilenya® With and Without Cognitive Impairment Over a 2 Year Period Using NeuroQuant, NeuroQuarc and ANAM
The purpose of the research study is to investigate whether the extent and severity of lesions in the brain as measured by special MRI techniques can distinguish between Multiple Sclerosis (MS) patients with or without memory…
- Trial name
- NeuroQuant (NCT05684016)
- Testing
- NeuroQuant, Automated Neuropsychological Assessment Matrices, EDSS
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- George Washington University
Multiple Sclerosis
Study of Fampridine-SR Tablets in Multiple Sclerosis Patients
The purpose of the study is to show that individuals treated with Fampridine-SR tablets are significantly more likely to have consistent improvements in their walking than those treated with placebo tablets.
- Trial name
- NCT00483652
- Testing
- Fampridine-SR
- Where
- 40 sites in United States, Canada
- Volunteers
- 240 people
- Sponsor
- Acorda Therapeutics
Nursing Caries
The Effect of the Human Care Model on Patients With Multiple Sclerosis
Purpose: This study was conducted to determine the effect of nursing care based on Watsons Human Caring Model on the quality of life of patients with MS.
- Trial name
- NCT06634758
- Testing
- Nursing interventions based on the Watson Human Caring Model
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Saglik Bilimleri Universitesi
Multiple Sclerosis
Multiple Sclerosis Falls Insight Track
The purpose of this study is to develop an application: MS Falls Insight Track (MS FIT) which allows patients to log their falls and near falls, view their MS relevant data and responses to the clinic intake survey as well as…
- Trial name
- MS FIT (NCT05837949)
- Testing
- MS FIT: Falls Insight Track
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Progressive Multiple Sclerosis, Neuromyelitis Optica.
Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica
Multiple sclerosis (MS) has been classically regarded as a chronic inflammatory autoimmune demyelinating disease of the central nervous system, along with a considerable pathological heterogeneity.
- Trial name
- NCT01364246
- Testing
- human umbilical cord mesenchymal stem cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shenzhen Beike Bio-Technology Co., Ltd.
Relapsing Remitting Multiple Sclerosis
Evaluation of Patient Reported Outcomes in RRMS Patients Candidates for MS Therapy Change and Transitioned to Fingolimod 0.5 mg (EPOC)
A 6-month, Randomized, Active Comparator, Open-label, Multi-Center Study to Evaluate Patient Outcomes, Safety and Tolerability of (fingolimod) 0.5 mg/day in Patients with Relapsing Remitting Multiple Sclerosis who are candidates…
- Trial name
- EPOC (NCT01534182)
- Testing
- Fingolimod, Interferon beta - 1a (IFN), Glatiramer acetate (GA)
- Where
- 26 sites in Russia
- Volunteers
- 298 people
- Sponsor
- Novartis Pharmaceuticals
Multiple Sclerosis
The 'Wearing Off' Effect of DMT
This is a non-interventional, cross-sectional, qualitative study in which patients diagnosed with MS and clinicians with experience treating MS will be interviewed regarding patient experiences with the wearing off effect from…
- Trial name
- NCT05627271
- Testing
- ocrelizumab, natalizumab, ofatumumab
- Where
- Switzerland
- Volunteers
- 39 people
- Sponsor
- Novartis Pharmaceuticals
Multiple Sclerosis, Dysphagia
Myotonometer Analyses of Muscles in Multiple Sclerosis Patients With Dysphagia
Multiple Sclerosis is a chronic inflammatory autoimmune neurological disease characterized by the destruction of myelin in the central nervous system, grey matter and axonal loss.
- Conditions
- Multiple Sclerosis, Dysphagia, Swallowing Disorder, Deglutition Disorders
- Trial name
- NCT04369092
- Testing
- DYMUS
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Tuba Maden
Neurologic Signs and Symptoms
Incidence, and Survival Medical Expenditure of Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a disease of autoimmune system which attacks the central nervous system and that is one of the most common inflammatory diseases and has caused a heavy disease burden on patients.
- Trial name
- NCT04022564
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- Chun-Ming Liao
Multiple Sclerosis, Urinary Bladder Diseases
Bladder Management in Patients With Multiple Sclerosis: Optimizing Practice Patterns
This study will assess the impact of a systematic bladder health screening and disease education regimen as well as the implementation of a referral process on the quality of life of multiple sclerosis patients with bladder…
- Trial name
- NCT01930799
- Testing
- Systematic Screening and Education Regimen
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Allergan
Multiple Sclerosis
Association Between Fatigue and Balance in Patients With Multiple Sclerosis
The relationship between fatigue and balance was established. Fatigue was correlated with 8 parameters of balance scales. Moreover, there was a strong correlation between the level of fatigue from one side and depression, quality…
- Trial name
- NCT04215354
- Testing
- Magnetic field, Virtual reality
- Where
- Saudi Arabia
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Secondary Progressive Multiple Sclerosis (SPMS)
Study of NG01 Cell Therapy in Secondary Progressive Multiple Sclerosis
The goal of this clinical trial is to assess the safety and efficacy of repeated intrathecal (IT) injection of NG01, autologous bone marrow derived human stromal cells, in treating Secondary Progressive Multiple Sclerosis (SPMS)…
- Trial name
- NCT06961383
- Testing
- NG01 - Autologous bone marrow derived human stromal cells, Sodium Chloride 0.9%
- Where
- 2 sites in United States, Israel
- Volunteers
- 45 people
- Sponsor
- NeuroGenesis Ltd.
Asthma
A Study of the Effect of FTY720 on Pulmonary Function in Patients With Moderate Asthma
This study will evaluate the effect of FTY720 on the lung function of patients with moderate asthma
- Trial name
- NCT00785083
- Testing
- FTY720
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Novartis
Multiple Sclerosis
Effectiveness of Exergaming in Adittion to Conventional Treatment for Physical Therapy in People with Multiple Sclerosis
The present study aims to evaluate the effectiveness of two different exergaming systems in addition to conventional treatment on physical functional capacity, balance, muscle strength, spasticity in lower limbs and quality of…
- Trial name
- NCT06196866
- Testing
- Conventional Therapy, Nintendo Ring Fit Adventure + Conventional Therapy, Nintendo Wii Fit + Conventional Therapy
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad de Córdoba
Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
The Effects of In-phase Bilateral Exercise in People with Progressive Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. MS, typical presents with progression of clinical symptoms which mainly include motor and cognitive impairment, as well as…
- Trial name
- NCT06436131
- Testing
- In-phase Bilateral Exercise, Conservative exercises
- Where
- Cyprus
- Volunteers
- 20 people
- Sponsor
- Cyprus University of Technology
Spasticity, Multiple Sclerosis
A Study of Sativex® for Relief of Spasticity in Subjects With Multiple Sclerosis.
The purpose of this study is to evaluate the efficacy, safety and tolerability of Sativex® in subjects diagnosed with MS and spasticity.
- Trial name
- NCT00711646
- Testing
- Sativex®
- Where
- United Kingdom
- Volunteers
- 189 people
- Sponsor
- Jazz Pharmaceuticals
Multiple Sclerosis
Effect of the Vojta Therapy in Patients Multiple Sclerosis
Multiple sclerosis is the most common disabling neurological disease in young adults. Inflammation, demyelination, neurodegeneration, gliosis and repair processes are involved in its process, which are responsible for the…
- Trial name
- NCT05558683
- Testing
- Randomized clinical trial.
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Aymara Abreu Corrales
Multiple Sclerosis, Sexual Dysfunction
Sexual Dysfunction in Patients With Relapsing Remitting Multiple Sclerosis and Associated Comorbidities
This work aims to: 1. Investigate and correlate Sexual Dysfunction in relapsing-remitting Multiple Sclerosis patients with specific focus on 1. Specific neurologic deficit. 2. Depressive symptoms. 3. Comorbid factors. 4.
- Trial name
- NCT04157283
- Testing
- MRI brain, visual evoked potential, Cerebrospinal Fluid, Sexual dysfunction measure, Depressive symptoms assessment and Multiple Sclerosis Quality of Life-54(MSQOL-54)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University Hospital
Multiple Sclerosis
Effects of Reiki and Self-Acupressure Applications
Reiki, the subject of our research, is a complementary medicine practice within energy approaches. Discovered in Sanskrit texts by Dr.
- Trial name
- NCT07083856
- Testing
- Reiki, Self-Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Firat University
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