Clinical trials: Pediatric Adenotonsillectomy
Procedural Anxiety, Procedural Pain
Auditory Intraoperative Stimulation Effects on Pain and Agitation at Awakening (AUDIOPAW)
Adenotonsillectomy (AT) is one of the most common pediatric surgical procedures. The management of postoperative pain and agitation after AT is still a controversial issue.
- Conditions
- Procedural Anxiety, Procedural Pain, Adenotonsillitis
- Trial name
- AUDIOPAW (NCT04112979)
- Testing
- Music, Mother's lap, Soundproof earplugs
- Where
- Italy
- Volunteers
- 115 people
- Sponsor
- IRCCS Burlo Garofolo
Emergence Delirium
Namsos Anaesthesia Children Outcome Study
Behavioral disturbances are often seen in children after anesthesia both immediately after surgery (emergence delirium) and after discharge from hospital.
- Trial name
- NACOS (NCT04292457)
- Testing
- Propofol, Sevoflurane
- Where
- 2 sites in Norway
- Volunteers
- 761 people
- Sponsor
- Helse Nord-Trøndelag HF
Sleep-Disordered Breathing
Pediatric Adenotonsillectomy Trial for Snoring
The purpose of this study is to evaluate the effects of early adenotonsillectomy (eAT) on the behavior, sleep-disordered breathing symptoms and quality of life for children who snore, but do not have obstructive sleep apnea, as…
- Trial name
- PATS (NCT02562040)
- Testing
- Early Adenotonsillectomy (eAT), Watchful Waiting with Supportive Care (WWSC)
- Where
- 7 sites in United States
- Volunteers
- 459 people
- Sponsor
- Brigham and Women's Hospital
Tonsillitis, Tonsillectomy
Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy
The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic…
- Trial name
- NCT03625011
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Emergence Agitation, Emergence Delirium
Transcutaneous Auricular Vagus Nerve Stimulation for Prevention of Emergence Agitation and Delirium in Children Undergoing Tonsillectomy and Adenoidectomy
Brief Summary This study is designed to find out whether transcutaneous auricular vagus nerve stimulation (taVNS) can safely reduce restlessness and confusion when children wake up from anesthesia after tonsillectomy and…
- Trial name
- NCT07394647
- Testing
- Active taVNS Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Obesity, Childhood, Cancer
NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors
Pediatric cancer survivors are at an increased risk of excessive weight gain and reduced exercise behaviors with the potential for this risk to worsen over time.
- Conditions
- Obesity, Childhood, Cancer, Survivorship
- Trial name
- NOURISH-T+ (NCT04656496)
- Testing
- NOURISH-T+, Brief NOURISH-T+
- Where
- 10 sites in United States
- Volunteers
- 520 people
- Sponsor
- University of South Florida
Obstructive Sleep Disordered Breathing
Adeno-tonsillectomy in Treatment of Obstructive Sleep Apnea
The aim of the study is to evaluate adenoidectomy with bilateral partial tonsillectomy compared with adenoidectomy with classical unilateral complete tonsillectomy for management of pediatric Obstructive Sleep-Disordered…
- Trial name
- NCT03475329
- Testing
- adenotonsillectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Molar-Incisor Hypomineralization (MIH)
Impact of Glass-Hybrid Restoration on Occlusal Force Distribution and Masticatory Muscle Activity in Children With Molar-Incisor Hypomineralization
This prospective pilot study evaluates the effect of restoring symptomatic, carious molar-incisor hypomineralization (MIH)-affected permanent molars using a glass-hybrid restorative material on occlusal force distribution and…
- Trial name
- NCT07336212
- Testing
- Glass-Hybrid Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Marmara University
Effect of Drug, Anxiety
Comparison Between Oral Melatonin and Hydroxyzine in Pediatric Patients Undergoing Adenotonsillectomy
Comparison between the effect of oral Melatonin and Hydroxyzine for Preventing Preoperative Anxiety in pediatric Patients Undergoing Adenotonsillectomy
- Trial name
- NCT05680584
- Testing
- Melatonin 3 MG, Hydroxyzine Pill
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Minia University
Pediatric Adenotonsillectomy, Post Operative Analgesia
Dexmedetomidine in Pediatric Tonsillectomy
The hypothesis of this study is that the administration of an intra-operative dose of dexmedetomidine will result in adequate analgesia without respiratory depression thereby resulting in an early discharge from the post…
- Trial name
- NCT01057381
- Testing
- Dexmedetomidine 0.75 mcg/kg, Morphine 50 mcg/kg, Morphine 100 mcg/kg
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Adenotonsillectomy
Impact of Problematic Media Use on Postoperative Pain in Children Undergoing Tonsillectomy
This observational study aims to investigate whether problematic media use is associated with postoperative pain severity in children aged 4-11 years undergoing tonsillectomy.
- Trial name
- NCT07297784
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Tokat Gaziosmanpasa University
Postoperative Pain
Perfusion Index as an Objective Measure for Postoperative Pain Assessment in Pediatric Patients.
It has been demonstrated that infants and children experience pain in a similar manner to adults, however it used to be undertreated when compared to adult.
- Trial name
- NCT03854604
- Testing
- postoperative pain assessment
- Where
- 3 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Adenotonsillectomy Surgery
Evaluation of Difficult Airway With Ultrasound
An unexpected difficult airway can lead to severe hypoxia and even death. Accurate airway assessment can reduce the incidence of difficult endotracheal intubation and related complications.
- Trial name
- NCT07057661
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Izmir City Hospital
Laryngeal Mask Airway, Tonsillectomy
Use of Laryngeal Mask Airway in Pediatric Adenotonsillectomy
The aim of the current study is to compare the use of laryngeal mask airway (LMA) and endotracheal tube (ETT) in pediatric adenotonsillectomy.
- Trial name
- NCT01141660
- Testing
- Endotracheal Tube, Laryngeal mask airway
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Virginia Commonwealth University
Emergence Delirium
Emergency Delirium in Pediatrics Undergoing Tonsillectomy and Adenoidectomy
Primary outcom Compare the effectiveness of study drugs on reducing the incidence of emergence delirium . Secondary outcomes: Sedation score Intensity of pain by FLACC Extubation time Iength of stay in Post anesthetic care unite…
- Trial name
- NCT06215768
- Testing
- Dexmedetomidine and Midazolam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Esraa Abdel Azez Soltan Mohamed Zayed
Emergence Delirium
Effect of Ketamine/Midazolam Premedication Versus Pre-extubation Ketofol on Recovery Profile in Pediatrics Undergoing Adenotonsillectomy.
An optimum recovery profile after AT includes a rapid, smooth awakening without emergence agitation (EA), stable vital signs and oxygenation, reduced postoperative nausea and vomiting (PONV), controlled postoperative pain, and…
- Trial name
- NCT06010927
- Testing
- ketamine/midazolam, Ketofol
- Where
- 2 sites in Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University
Adenotonsillectomy, Analgesia
Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity
The goal of this study is determine if an oral systemic course of steroids is a safe and effective option in lowering pain and complications following adenotonsillectomy in various pediatric age groups.
- Conditions
- Adenotonsillectomy, Analgesia, Surgery
- Trial name
- NCT04879823
- Testing
- Dexamethasone, Ibuprofen, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 222 people
- Sponsor
- David Chi, MD
Sleep Disorder; Breathing-Related, Pain, Postoperative
Comparison of Peritonsillar Infiltration of Tramadol Ketamine and Placebo on Pediatric Posttonsillectomy Pain
Adenotonsillectomy is one of the most common ambulatory surgical procedures performed to children. Tonsillectomy or adenotonsillectomy have a high incidence of postoperative pain.
- Conditions
- Sleep Disorder; Breathing-Related, Pain, Postoperative, Child, Only
- Trial name
- NCT03067103
- Testing
- Tramadol, Ketamine
- Where
- Brazil
- Volunteers
- 108 people
- Sponsor
- Universidade Federal de Goias
Pain
iPad for Post Operative Pain After Tonsillectomy
The purpose of this study is to determine the clinical effectiveness of presenting iPads (Tablet Based Interactive Distraction) to pediatric patients following tonsillectomies/adenotonsillectomies.
- Trial name
- NCT07770529
- Testing
- iPad, Intervention Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Tonsillectomy
Muscle Relaxation for Pediatric Adenotonsillectomy
The goal of this clinical trial is to compare general anesthesia with muscle relaxation and reversal of the relaxation at the end of surgery or without muscle relaxation in high-risk children having adenotonsillectomy surgery.
- Trial name
- NCT06225466
- Testing
- Rocuronium, Sugammadex, Anesthesia without neuromuscular blockade
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- University of Texas Southwestern Medical Center