Clinical trials: Pediatric Chronic Pain
Chronic Pain, Child
Exercise as Medicine for Pediatric Chronic Pain
Youth with chronic pain struggle to go to school, play sports, or spend time with friends and family due to pain. Medications are often ineffective, and aerobic exercise may improve both pain sensitivity and participation in…
- Conditions
- Chronic Pain, Child, Adolescent
- Trial name
- NCT07182006
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Systemic Juvenile Idiopathic Arthritis (SJIA)
ß-SPECIFIC 4 Patients: Study of Pediatric EffiCacy and Safety wIth FIrst-line Use of Canakinumab
The purpose of this study was to evaluate the efficacy observed with canakinumab dose reduction in a subgroup of patients in the extension study CACZ885G2301E1.
- Trial name
- ß-SPECIFIC 4 (NCT02296424)
- Testing
- ACZ885 150 mg (Canakinumab)
- Where
- 50 sites in United States, Austria and 14 more
- Volunteers
- 182 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Migraine, Headache, Episodic Migraine
Occipital Blocks for Acute Migraine
Migraine affects 10-28% of children and adolescents and yet 20-30% of patients are ineffectively treated with current oral and nasal options.
- Trial name
- NCT03526874
- Testing
- Lidocaine 4% Topical Application Cream [LMX 4], Lidocaine Hydrochloride 2 mg/mL Injectable Solution, Normal Saline
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Children's Hospital of Philadelphia
Neuropathic Pain, Chronic Pain
Pediatric Electrocutaneous Analgesia for Children Experiencing Neuropathic Pain
This is a study evaluating the Scrambler Therapy device as a non-invasive treatment for neuropathic pain in pediatric oncology patients with metastatic bone disease.
- Trial name
- PEACE-NP (NCT07264920)
- Testing
- Scrambler Therapy MC-5A Device
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Chronic Pain, Pain
Effectiveness of a Pain Science Education Programme in Adolescent Students.
The aim of this study is to analyze the effectiveness of a Pain Science Education program to improve the conceptualization of pain in adolescents between 11 and 13 years old, schooled in the first year of Compulsory Secondary…
- Conditions
- Chronic Pain, Pain, Pediatric ALL
- Trial name
- EDEA (NCT06060431)
- Testing
- Pain Science Education
- Where
- Spain
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Pain, Postoperative, Scoliosis Idiopathic
Gabapentin and Chronic Post Surgical Pain
The purpose of this study is to investigate the effect of a common pain medication (gabapentin) on chronic postsurgical pain in pediatric patients who require surgery for idiopathic scoliosis.
- Trial name
- CPSP (NCT03867240)
- Testing
- Gabapentin
- Where
- United States
- Sponsor
- Emory University
Thoracic Surgery, Scoliosis; Adolescence
Chronic Pain After Scoliosis and Thoracic Surgery in Children
The aim of this epidemiologic prospective study is to determine the prevalence of CPSP defined as pain occurring 4 months after scoliosis and thoracic surgery and rated > 3 on a 10 point visual analogue scale or FLACC scale, in…
- Conditions
- Thoracic Surgery, Scoliosis; Adolescence, Pediatric ALL, Chronic Pain
- Trial name
- PEDIACHROII (NCT02995525)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Bordeaux
Chronic Pain in the Extremities, Chronic Abdominal Pain
Screening for Fabry Disease in a Pediatric Population at Risk
The purpose of this study is to assess the frequency of Fabry disease in children with chronic abdominal pain or chronic pain in the extremities
- Conditions
- Chronic Pain in the Extremities, Chronic Abdominal Pain, Fabry Disease
- Trial name
- NCT02152189
- Testing
- Screening for Fabry disease
- Where
- Germany
- Volunteers
- 1,422 people
- Sponsor
- University Hospital Heidelberg
Osteomyelitis Chronic
EFFICACY AND SAFETY OF ZOLEDRONATE VERSUS PLACEBO ON PAIN AT WEEK 12 IN PEDIATRIC PATIENTS WITH CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare auto-inflammatory bone disease that primarily affects children and/or adolescents at a median age of 10 years.
- Trial name
- POMREP (NCT07668583)
- Testing
- Zoledronic Acid / Zoledronate 4 MG/100 ML Intravenous Solution, NaCL 0.9% Intravenous Solution
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Migraine
Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine
This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and adolescents (12 to <18 years) with chronic migraine.
- Trial name
- OASIS(CM) (NCT03832998)
- Testing
- Erenumab Dose 1, Erenumab Dose 2, Erenumab Dose 3
- Where
- 101 sites in United States, Belgium and 11 more
- Volunteers
- 284 people
- Sponsor
- Amgen
Headache
Pediatric Chronic Headache Trial
The purpose of this trial is to evaluate the efficacy of combined behavioral and pharmacological treatment on chronic daily headache in children ages 10 to 17.
- Trial name
- NCT00389038
- Testing
- Coping Skills Training, Headache Education, Amitriptyline
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Pancreatitis, Chronic Pain
Pancreatic Quantitative Sensory Testing (P-QST)
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Conditions
- Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
- Trial name
- NCT06996535
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Postoperative Pain, Pediatric ALL
Chronic Postsurgical Pediatric Pain. Evaluation Risk Factors to Develop Chronic Postsurgical Pain in Children and Adolescents Undergoing Surgery in a First Level Hospital
Chronic postsurgical pain had number of prevalence on 20%. Its derivates from risk factors, but recent research provide new potential risk factors to develop chronic postsurgical pediatric pain.
- Trial name
- NCT04735211
- Testing
- Surgery
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Guillermo Ceniza Bordallo
Chronic Pain
A 15-day Study to Assess the Safety and Clinical Utility of Duragesic (Fentanyl Transdermal Patch) in the Treatment of Children With Continuous Pain Requiring Narcotic Pain Relief Therapy
The objective of this study is to assess the safety and clinical utility of Duragesic® 12.5 micrograms/hour (a transdermal patch delivering the narcotic pain-reliever fentanyl) in the treatment of children ages 2 to 12 with…
- Trial name
- NCT00271414
- Testing
- Duragesic® (fentanyl) Transdermal Therapeutic System (TTS)
- Volunteers
- 53 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Chronic Pancreatitis, Acute Recurrent Pancreatitis
Internet Based Cognitive Behavioral Therapy in Pediatric Chronic Pancreatitis
Abdominal pain is common in children with chronic and acute recurring pancreatitis (CP, ARP), and as they continue into adulthood, the disease progresses with increased pain and greater exposure to opioids.
- Trial name
- NCT03707431
- Testing
- Web-based CBT, Pain Education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Seattle Children's Hospital
Burns, Knee Injuries
Opioid Laws and Pediatric Use
The legitimate need for opioid medications for acute pain management in pediatric trauma patients is recognized, however, the high dose and duration of opioid drugs prescribed by medical providers has been associated with an…
- Conditions
- Burns, Knee Injuries, Opioid Use, Pain
- Trial name
- NCT04543227
- Testing
- Opioid Use 90-Days Post Treatment
- Where
- United States
- Volunteers
- 980 people
- Sponsor
- Nationwide Children's Hospital
Chronic Pain, Body Mass Index >=85th Percentile
Probiotics for Inflammation in Pediatric Chronic Pain
To examine benefits of a probiotic for youth with chronic pain and a Body Mass Index >=85th percentile.
- Trial name
- NCT05141890
- Testing
- Lactobacillus Plantarum
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Medical College of Wisconsin
Neuropathic Pain, Chronic Pain
Observational Study of the Use of 8% Capsaicin Patch in Children 0 to 18 Years Old
Patients aged less than 18-y with validated 8% capsaicin patch treatment in routine healthcare will be offered to participate the study. If they accept it as well as their parents, they will be included in the study .
- Trial name
- CAPSULE (NCT05299294)
- Testing
- Data collection
- Where
- 20 sites in France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Brest
Chronic Pain
A Study to Assess the Safety, Dose Conversion, and Dose Individualization of Duragesic® (Fentanyl Transdermal Patch) in the Treatment of Children With Chronic Pain Requiring Narcotic Pain Relief Therapy
The objective of this study is to assess the safety of treatment with Duragesic® (a transdermal patch delivering the narcotic pain-reliever fentanyl) in doses of 12.5, 25, 50, 75 and 100 micrograms/hour in pediatric subjects…
- Trial name
- NCT00271466
- Testing
- Duragesic® (fentanyl) Therapeutic Transdermal System (TTS)
- Volunteers
- 199 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Vomiting Syndrome, Irritable Bowel Syndrome
Autonomic Profiles in Pediatric Patients With Cyclic Vomiting Syndrome (CVS), Irritable Bowel Syndrome (IBS),Postural Orthostatic Tachycardia Syndrome (POTS), Functional Abdominal Pain (FAP) or Chronic Nausea
Retrospectively review the charts of all children who had heart rate variability, deep breathing test, valsalva maneuver, tilt table test, thermoregulatory sweat testing, quantitative sudomotor axon reflex test (QSART) completed…
- Conditions
- Vomiting Syndrome, Irritable Bowel Syndrome, Postural Orthostatic Tachycardia Syndrome, Abdominal Pain
- Trial name
- NCT00728026
- Volunteers
- 19 people
- Sponsor
- Medical College of Wisconsin