Clinical trials: Pediatric Critical Illness
Dobutamine, Milrinone , Pediatrics , Low Cardiac Output
Dobutamine Versus Milrinone in Management of Critically Ill Low Cardiac Output Pediatric Patients at Cairo University Children's Hospital
The aim of the study is to detect wither dobutamine or milrinone have a privilege in the management of low cardiac output pediatric patients over the other.
- Trial name
- NCT05999487
- Testing
- Dobutamine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Sepsis, Hyperglycemia
Gluconeogenesis Rates and Its Precursors in Pediatric Sepsis
Critically ill children have abnormal utilization of nutrients such as glucose, lipids and protein. Often sick children have increased glucose concentrations in blood.
- Conditions
- Sepsis, Hyperglycemia, Critical Illness
- Trial name
- NCT01890928
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Hemoglobin Results
Comparing Validity of Non-Invasive Hemoglobin Monitoring to Laboratory Results in Critically Ill Children
This is a prospective study to determine the accuracy of the Masimo Pronto Non-Invasive Hemoglobin Monitor and associated Rainbow® probes in the detection of hemoglobin concentration in critically ill children.
- Trial name
- NCT01750463
- Testing
- Masimo Pronto Rad 7 Non-Invasive hemoglobin monitor, Standard Laboratory Blood Draw and Hemoglobin Analysis
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of North Carolina, Chapel Hill
Critical Illness, Multiple Organ Dysfunction Syndrome
pSOFA Score in Predicting Mortality in Pediatric Intensive Care
This prospective observational cohort study aims to evaluate the predictive performance of the Pediatric Sequential Organ Failure Assessment (pSOFA) score for mortality and selected clinical outcomes among critically ill children…
- Trial name
- NCT07858487
- Volunteers
- 121 people
- Sponsor
- Assiut University
Delirium
Quetiapine Treatment for Pediatric Delirium
This is a prospective, double-blind, randomized controlled trial to begin determining the efficacy of quetiapine as a treatment for pediatric delirium in patients admitted to the pediatric intensive care unit (PICU)
- Trial name
- NCT03572257
- Testing
- Quetiapine
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Low Cardiac Output
Comparison of Techniques for Assessing Cardiac Output and Preload in Critically Ill Pediatric Patients
Each year in the United States more than 30,000 children are admitted to intensive care units. The majority of these children have some degree of heart instability during their stay, yet there is currently no routine way to…
- Trial name
- NCT00167440
- Where
- United States
- Sponsor
- University of Rochester
Lung Collapse
Brochoscopic Intervention Versus Conventional Management in Acute Lung Collapse in the Pediatric Intensive Care Unit
This prospective RCT at Cairo University Children Hospitals enrolls critically ill pediatric patients (intubated, NIV, or post-extubation) with lung atelectasis unresponsive to 48 hours of conventional recruitment.
- Trial name
- picu (NCT07383129)
- Testing
- bronchoscope, chest physiotherapy and suction
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Critical Illness, Sedation Complication
Dexmedetomidine Cycling and Sleep in the Pediatric ICU
This is a study of mechanically ventilated pediatric intensive care unit (ICU) teenage patients and the effects of the medication dexmedetomidine on sleep, delirium, and sedation level.
- Conditions
- Critical Illness, Sedation Complication, Delirium
- Trial name
- NCT05003102
- Testing
- Dexmedetomidine Hydrochloride - Cycling, Fentanyl - PICU Standard, Dexmedetomidine Hydrochloride - PICU Standard
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Critical Illness, Pediatric Intensive Care Unit
COPM-Based Goal Setting Strategies in the PICU
COPM-Based Goal Setting Strategies in the PICU
- Trial name
- NCT07128446
- Testing
- Standard physical and occupational therapy
- Where
- 2 sites in South Korea
- Volunteers
- 5 people
- Sponsor
- Samsung Medical Center
Eye Injuries, Critically Ill
Does the Use of a Moisture Chamber Decrease the Incidence of Corneal Abrasions in Critically Ill Pediatric Patients?
The purpose of this study is to identify the incidence of scratches on the surface of the eye in children who cannot blink due to medication use and to identify how best to reduce the risk of a scratch on the surface of the eye…
- Trial name
- NCT00129077
- Testing
- plastic wrap over eye & lubrication applied q6 hrs
- Where
- 2 sites in United States
- Volunteers
- 207 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Multiple Organ Failure
Feasibility Study of MicroKine Dx System in Critically-ill Pediatric Patients.
This study will enroll approximately 25 pediatric patients to assess the performance and real-world feasibility of multi-biomarker based prognostic and predictive algorithms to aid in the clinical management of pediatric…
- Trial name
- NCT04295278
- Testing
- MicroKine Dx system
- Volunteers
- 25 people
- Sponsor
- PreDxion Bio, Inc.
Critical Illness, Pediatric Intensive Care
Continuous vs Bolus Protein (Protein Regimen Outcomes) in Critically Ill Children (Kids In Distress)
The goal of this intervention study is to evaluate the difference in nutrition status markers (weight and muscle mass) when giving dietary protein by continuous or bolus delivery in critically ill children ages 1-11y.
- Conditions
- Critical Illness, Pediatric Intensive Care, Enteral Nutrition Therapy, Dietary Protein
- Trial name
- PRO-KID (NCT06721923)
- Testing
- Dietary protein
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Airway Management
Apneic Intubation Critically Ill Children
This study compares the actual standard of care of intubation in Swiss pediatric intensive care units vs the use of apneic oxygenation using either high flow or low flow oxygen to prevent hypoxemia and to prolong apnea time…
- Trial name
- Penguin (NCT04890288)
- Testing
- Interventional randomized controled trial (RCT) comparing two oxygenation methods to reduce desaturation during intubation vs standard of care.
- Where
- 7 sites in Switzerland
- Volunteers
- 210 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern