Clinical trials: Pediatric Health
Heart Disease, Health
Molecular Forms of Plasma and Urinary B-type Natriuretic Peptide and Its N-terminal Prohormone in Health and Disease in Pediatric Cardiology
B-type natriuretic Peptide (BNP) is a cardiac hormone secreted from the cardiac myocytes in response to volume load. Plasma levels of BNP, as measured by immunoassay methods, are elevated in patients with heart diseases.
- Trial name
- NCT01603888
- Testing
- no intervention
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Obesity, Childhood
Teens Committed to Health Through Activity, Relationships, and Good Eating
This study will evaluate the preliminary efficacy of a school-based weight management program for underserved adolescents. The program was designed with a phased treatment structure to provide more intensive treatment to…
- Trial name
- Take CHARGE! (NCT04362280)
- Testing
- ReCHARGE, TAU
- Where
- United States
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- University of Houston
Lymphangioma, Lymphatic Malformations
Bleomycin as an Effective and Curative Adjunct Therapy for Lymphangioma
Lymphatic malformations (LM), or lymphangiomas, are common vascular anomalies in children, most often occurring in the head and neck, less commonly in the axilla, abdomen, thorax, groin, and extremities.
- Trial name
- NCT06943703
- Testing
- Sclerotherapy with intralesional bleomycin injection
- Where
- Vietnam
- Volunteers
- 809 people
- Sponsor
- National Children's Hospital, Vietnam
Childhood Obesity
Computerised Decision-Support Tool for Childhood Obesity Management
The objective of the present study was to examine the effectiveness of a computerised decision-support tool, developed to assist paediatric clinicians in delivering personalised nutrition and lifestyle optimization advice to…
- Trial name
- NCT03819673
- Testing
- Intervention Group Care
- Where
- Greece
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Ear Infection
Application of the Belle.AI Comparative Image Reference System for Describing Chronic Ear Infections in Pediatric Patients From Low-Resource Communities
The purpose of this research is to examine the clinical effectiveness of an investigational AI-powered smartphone app that describes the physical characteristics of an otoscopy image. It is not intended to make any diagnosis.
- Trial name
- Otoscopy AI (NCT07025473)
- Testing
- Smartphone-enabled otoscopy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- BelleTorus Corporation
Congenital Heart Disease
TORCH-LATAM: A Regional Pathway to Improve Transplant Evaluation for Congenital Heart Disease
Congenital heart disease can progress to advanced cardiac or cardiopulmonary failure requiring heart, heart-lung, or, in selected congenital conditions, bilateral lung transplantation with cardiac repair.
- Trial name
- TORCH-LATAM (NCT07799272)
- Testing
- TORCH Integrated Transplant Access Pathway (TORCH-ITAP)
- Volunteers
- 600 people
- Sponsor
- CardioVision International Tech, S.A.S. de C.V.
Pediatric Obesity
Effects of Digital Health Interventions on the Motivation, Health-related Behavior and Mental Health of Middle School Students
The goal of this cluster-randomized clinical trial is to learn whether digital interventions, especially a motivational interviewing (MI) chatbot can improve adolescents' physical activity motivation and behavior, as well as…
- Trial name
- NCT06547567
- Testing
- MI chatbot Intervention, General-counseling chatbot intervention, Graphic-text intervention
- Where
- China
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Peking University
Asthma
Investigation of the Role of Pictorial Asthma Action Plans to Promote Self-management in Rural Youth With Asthma
The aim of this study is to investigate the potential benefit of Pictorial versus Written Asthma Action Plans (AAPs) to support asthma management among young people with persistent asthma.
- Trial name
- TAAC (NCT03187119)
- Testing
- Pictorial Asthma Action Plan, Written Asthma Action Plan
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- West Virginia University
Obesity, Adolescent
The Effects of a Combined Exercise Training Program on Vascular Health and Metabolic Profile in Obese Adolescent Girls.
The purpose of this study was to examine the impact of 12 weeks of combined exercise training (CET) on arterial stiffness, endothelial function, inflammatory markers, insulin resistance, and body composition in obese adolescent…
- Trial name
- NCT03146026
- Testing
- Combined Exercise Training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pusan National University
Hematopoietic Stem Cell Transplantation
Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors
The purpose of this pilot study is to investigate the safety and preliminarily assess efficacy of early intervention with zoledronate in high risk pediatric hematopoietic stem cell transplantation (HSCT) patients to prevent the…
- Trial name
- NCT07375290
- Testing
- Zoledronate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cochlear Implant, Hearing Loss
CRESCENDO: ChildREn's muSiC ENhancement in Cochlear Implant Users
This exploratory, single-center, single-arm study investigates the impact of a 12-week Multimodal Acoustic Therapy (MAT) intervention followed by a 12-week follow-up period on both objective and subjective auditory perception in…
- Trial name
- NCT07297524
- Testing
- Mobile Auditory Rehabilitation
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Seoul National University Hospital
Mental Health, Mental Disorders
An Innovative Model of Pediatric Acute Mental Health and Addictions Care
The investigators will implement and evaluate an integrated, evidence-based bundle of family-centred, pediatric emergency mental health and addictions care.
- Conditions
- Mental Health, Mental Disorders, Pediatrics, Emergency Psychiatric
- Trial name
- NCT04292379
- Testing
- Standard care, Care Bundle
- Where
- 2 sites in Canada
- Volunteers
- 1,992 people
- Sponsor
- University of Alberta
Pediatric Obesity, Mobile Technology
An Addiction-Based Mobile Health Weight Loss Intervention With Coaching
The proposed multi-site randomized control trial (RCT) will test the effectiveness of an addiction-based weight loss intervention, embodied first as a smartphone app with telephone coaching and second as an identical approach…
- Conditions
- Pediatric Obesity, Mobile Technology, Addiction
- Trial name
- NCT03500835
- Testing
- App, Coaching, Clinic: Modified KidsNFitness
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- Children's Hospital Los Angeles
Pediatric Obesity, Health Literacy
Enhancing Childhood Obesity Interventions Through Digital Media Tools
This study evaluated the effectiveness of a LINE Official Account (a mobile messaging platform) as a digital health education tool to enhance parental engagement with childhood obesity-related health literacy content.
- Trial name
- NCT07501546
- Testing
- Immediate Automated Push Notifications, Delayed Automated Push Notifications
- Where
- Taiwan
- Volunteers
- 567 people
- Sponsor
- Taipei City Hospital
Long Bone Fractures
Registry of Pediatric Orthopedic Trauma and Health Outcomes in Skeletally Immature Children
International registry to collect prospective treatment and outcomes data on specific, key non-pathological fractures in children with open physes.
- Trial name
- NCT04207892
- Testing
- Conservative (non-surgical) treatment, Surgical treatment
- Where
- 17 sites in United States, Australia and 10 more
- Volunteers
- 1,000 people
- Sponsor
- AO Innovation Translation Center
Chronic Health Condition, Cognitive Disability
Primary Care Transition Study
This study is looking at ways to help young people with chronic health conditions take better care of their health and find an adult doctor.
- Trial name
- NCT01750892
- Testing
- REACH for Independence, Transition Consult, Study Materials
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Children's Hospital of Philadelphia
Specific Learning Disabilities, Dental Caries
Dental Caries and Oral Hygiene Status in Children With Specific Learning Disabilities
This study aims to evaluate dental caries and oral hygiene status in children aged 7-12 years with specific learning disabilities (SLD) and to compare the findings with healthy children.
- Conditions
- Specific Learning Disabilities, Dental Caries, Oral Hygiene
- Trial name
- SLD-OH (NCT07611981)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Postoperative Pulmonary Complications, Postoperative Pulmonary Atelectasis
Evaluation of the Effect of Perioperative Recruitment Maneuver Practice on Lung Ultrasound Score and Mechanical Power in Pediatric Patients
Pulmonary atelectasis is common during general anesthesia and increases the risk of hypoxemia, especially in pediatric patients. PEEP and recruitment maneuvers (RM) are effective in preventing atelectasis.
- Conditions
- Postoperative Pulmonary Complications, Postoperative Pulmonary Atelectasis, Pediatric Surgery
- Trial name
- LUS RM PEEP (NCT07294560)
- Testing
- recruitment maneuver, right and left lateral decubitus position recruitment maneuvers
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Istanbul University - Cerrahpasa
Pediatric, Well Child Care
Comparing a Team-Based Approach to Standard Well-Child Visits To Improve Preventive Care Services
Parent-focused Redesign for Encounters, Newborns to Toddlers (PARENT) is a team-based approach to care that utilizes a community health worker in a health educator role ("Parent's Coach") to provide many of the Well-Child Care…
- Trial name
- NCT05852392
- Testing
- Adapted PARENT Model
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Persistent Allergic Rhinitis
Oxymetazoline Bridge Therapy With Intranasal Corticosteroids in Pediatric Allergic Rhinitis
Persistent allergic rhinitis in children is commonly treated with intranasal corticosteroids (INS), which are considered first-line therapy.
- Trial name
- NCT07593898
- Testing
- Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg, Oxymetazoline 0.05% nasal solution
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Dr. Behcet Uz Children's Hospital