Clinical trials: Pediatric Health
Obesity, Childhood
Addressing Health Disparities in Childhood Obesity, One Summer at a Time
Almost 50% of Native American and Hispanic children are overweight or obese by the 5th grade. Research has demonstrated that the 'obesity gap' facing minority students is largely due to summer weight gain.
- Trial name
- NCT03595332
- Testing
- Summer activity program
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Smoking Cessation
The OneFlorida Cancer Control Alliance: Implementing the 6As in Pediatric Primary Care
The primary purpose of our study is to conduct a pilot, practice-based intervention focused on increasing adherence to the 6As for youth ages 11 through 17 years.
- Trial name
- NCT03044691
- Testing
- ResearchACTS software
- Where
- 3 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pediatric Cancer, Febrile Neutropenia
Feasibility of Monitoring Health Data in Pediatric Patients Undergoing Chemotherapy
In this pilot study the feasibility of continous monitoring of health data with a small, on-skin wearable device (the Everion®, by Biovotion, Zurich) in pediatric patients under chemotherapy for cancer, is studied.
- Conditions
- Pediatric Cancer, Febrile Neutropenia, Chemotherapy-induced Neutropenia, Oncology
- Trial name
- NCT04134429
- Testing
- Everion
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Multiple Chronic Conditions, Children With Medical Complexity
Understanding Factors in Decision Making for Children With Medical Complexity
The goal of this clinical trial is to compare different strategies to communicate around potential risks and benefits related to treatment decision making in parents/adult caregivers of children with medical complexity.
- Trial name
- NCT05913206
- Testing
- Ambiguity, Complexity, Normalizing language
- Where
- 2 sites in United States
- Volunteers
- 831 people
- Sponsor
- University of Utah
Obesity, Infant, Language Development
Music and Child Health and Development
The goal of this clinical trial is to learn about the effects of a music enrichment program on the quality of parent child interactions, a child's motivation to eat, and a child's language environment in 9 to 24 month-old…
- Conditions
- Obesity, Infant, Language Development, Parent-Child Relations
- Trial name
- NCT05868811
- Testing
- Music Together, Play Group
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
HIV
A Phase II/III Trial of Lopinavir/Ritonavir Dosed According to the WHO Pediatric Weight Band Dosing Guidelines
Treatment of children and infants with HIV requires modification of medication dosing according to a child's specific weight. For lopinavir/ritonavir (LPV/r), a second line treatment option that is increasingly necessary due to…
- Trial name
- NCT01172535
- Testing
- Lopinavir/ritonavir
- Where
- 19 sites in United States, Brazil and 2 more
- Volunteers
- 97 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chronic Toxic Stress, Developmental/ Behavioral Regression in Young Children
(YMP) Young Moms Program
Young Moms Program (YMP) is designed to address systemic barriers to the health and stability of young moms and their children such as the lack of coordination of service delivery or logistical barriers within the health system.
- Trial name
- YMP (NCT05082857)
- Testing
- "traditional" Parents as Teachers (PAT), "hybrid" PAT model
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Mental Health Issue, Teamwork
Team-Focused Implementation in Child Advocacy Centers
Child Advocacy Centers (CACs) are well-positioned to identify children at risk for mental health problems and to facilitate access to evidence-based treatments.
- Trial name
- NCT05679154
- Testing
- Team-focused Implementation, Standard Implementation
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- University of Pittsburgh
Pediatric Obesity, Executive Function
Cognitive Aspects of Response to Treatment for Weight-related Health to Improve Eating and Exercise Earlier in Life
We plan to examine whether child and parental cognitive/executive function predict body composition outcomes and adherence to a 6-month protocol of Family-Based Behavioral Treatment (FBT), for pediatric obesity.
- Trial name
- CARTWHEEL (NCT03329300)
- Testing
- Family-based Behavioral Treatment (FBT)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Alabama at Birmingham
Sickle Cell Trait
Increasing Documentation and Disclosure of Sickle Cell Trait Status: An Implementation Science Approach
The hemoglobinopathy newborn screen (NBS) performed on all neonates in the U.S. allows for early life-saving medical care for infants with sickle cell disease (SCD), an autosomal recessive genetic disorder.
- Trial name
- NCT05387564
- Testing
- SCT Documentation and Disclosure Toolkit (SCT-DD)
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Nemours Children's Clinic
Pediatric Cancer
Mindfulness-based Intervention for Teenagers With Cancer
The purpose of this study is to evaluate the effects of a mindfulness-based meditation intervention on quality of life, sleep and mood in adolescents with cancer compared to a control group.
- Trial name
- NCT01783418
- Testing
- Mindfulness Intervention
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- St. Justine's Hospital
Stem Cell Transplant, Adherence, Medication
BMT4me: Post-HSCT Medication Adherence mHealth App
This is a mixed methods, prospective longitudinal pilot RCT to evaluate the 1) acceptability of a newly developed mHealth app (BMT4me), 2) the feasibility of enrolling and retaining caregivers of children in the acute phase…
- Conditions
- Stem Cell Transplant, Adherence, Medication, Digital Health
- Trial name
- Bmt4me 2 (NCT05515497)
- Testing
- BMT4me 2.0 app
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Micah Skeens
Crohn Disease
Bone Health in Pediatric Crohn's Disease: A Low Magnitude Mechanical Stimulus Trial
The purpose of this 12-month double blind, placebo controlled randomized trial is to evaluate the effects of daily treatments with low magnitude mechanical stimuli on bone in 160 children with Crohn disease.
- Trial name
- NCT00364130
- Testing
- Low magnitude mechanical stimulus
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Children's Hospital of Philadelphia
Caries, Dental, Health Behavior
Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children
This is a randomized clinical trial to test the efficacy of a parent-targeted text message-based intervention program on caries incidence and oral health behaviors (child and parent).
- Trial name
- iSmile (NCT03294590)
- Testing
- OHT Parent targeted text messages, CWT Parent targeted text messages
- Where
- United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Boston University
Obesity
W8Loss2Go: mHealth Weight Management Strategy
The investigators will test a recent mobile technology based (mHealth) behavioral weight loss intervention (W8Loss2Go), which is designed for children and adolescents, and uses an addiction model to promote withdrawal from…
- Trial name
- NCT02689154
- Testing
- W8Loss2Go
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital Los Angeles
Obesity, Cancer
Targeting Caregivers to Enhance Health Behaviors in Pediatric Cancer Survivors
This purpose of this pilot study is to investigate the feasibility of and optimal time post cancer treatment to offer caregivers a new health behavior change intervention (NOURISH-T), as well as assess its preliminary efficacy on…
- Trial name
- NOURISH-T (NCT02815982)
- Testing
- NOURISH-T, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 106 people
- Sponsor
- University of South Florida
Smoking Cessation
An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients
This study will test the efficacy of a cessation intervention for caregivers in a large, inner-city Pediatric Emergency Department.
- Trial name
- NCT02531594
- Testing
- SBIRT, HHC
- Where
- United States
- Volunteers
- 770 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Health Knowledge, Attitudes, Practice
Impact, Feasibility, and Acceptability of Bladder Basics
PLUTS remains a common childhood condition despite effective treatment options. It is important to improve delivery of UT at the clinical level, with future studies that shift pediatric bladder health into a broader community…
- Trial name
- Bladder Basics (NCT05852353)
- Testing
- Digital Pediatric Bladder Health Patient Education Curriculum
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Stanford University
Transfusion-dependent Anemia
Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload
This was a randomized, open-label, multicenter, two arm, phase II study to evaluate treatment compliance and change in serum ferritin of a deferasirox granule formulation and a deferasirox dispersible tablet (DT) formulation in…
- Trial name
- NCT02435212
- Testing
- Deferasirox granule formulation, Deferasirox DT formulation
- Where
- 43 sites in United States, Belgium and 15 more
- Volunteers
- 224 people
- Sponsor
- Novartis Pharmaceuticals