Clinical trials: Pediatric Neurological Disorder
Breakthrough Pain, Palliative Medicine
Paediatric Breakthrough Pain Assessment
Many children and young people with life-limiting and life-threatening illnesses get sudden bursts of pain called breakthrough pain. At the moment, there aren't any good ways to measure this pain in children and young people.
- Conditions
- Breakthrough Pain, Palliative Medicine, Oncology Pain, Pediatric ALL
- Trial name
- BEACON (NCT06790719)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Epilepsy
Transcutaneous Auricular Vagus Nerve Stimulation for Pediatric Epilepsy
The purpose of this study is to determine whether transcutaneous auricular vagus nerve stimulation as a complementary therapy is effective in the treatment of pediatric epilepsy.
- Trial name
- NCT02004340
- Testing
- ear vagus nerve stimulator
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- China Academy of Chinese Medical Sciences
Pain, Anxiety
Estimation of Analgetic Effect and Cooperability of Pediatric Patients During Application of Gass Mixture of Oxygen:Nitrogen Suboxide 50%:50% for Minimal Invasive Procedures
The goal of this observational study is to observe analgetic and anxiolytic effect of gass mixture of oxygen:nitrigen suboxide 50%:50% in pediatric patients sujected to minimal invasive procedures.
- Conditions
- Pain, Anxiety, Sedation
- Trial name
- NCT07159425
- Where
- Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mother and Child Health Institute of Serbia Dr Vukan Cupic
Caregiver Burden, Stroke
Evaluation of Musculoskeletal System in Caregivers of Rehabilitation Patients
In this study, musculoskeletal-related pain, posture, spine function, the condition of the low back and neck regions, musculoskeletal system disorders, fatigue, and quality of life will be examined in caregivers of rehabilitation…
- Conditions
- Caregiver Burden, Stroke, Cerebral Palsy, Neurologic Disorder
- Trial name
- NCT05839795
- Testing
- Assessment study
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Cerebral Palsy (CP)
FES Implementation Pediatrics
Physical rehabilitation interventions that promote activity-dependent neuroplasticity are desired for children with CP as this will result in improved motor skill and function.
- Trial name
- NCT06689007
- Testing
- Implementation Intervention
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Amblyopia, Myopia
Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population
Screening of haitian children between the ages of 3 and 6 years old for amblyogenic risk factors with the use of the Spot photoscreener. The photoscreener results will be compared to the complete ophthalmologic evaluation.
- Conditions
- Amblyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- POPH (NCT02655432)
- Testing
- Spot photoscreener, Ophthalmologic evaluation, Cyclopleged refraction
- Where
- 3 sites in Haiti
- Volunteers
- healthy volunteers welcome
- Sponsor
- Université de Montréal
Diabetes Mellitus, Type 1, Behavior, Health
Game-based Pediatric Diabetes Education
The goal of this study is to evaluate the impact of a mobile app video game called Digital Vaccine for Type 1 Diabetes (DVx-T1D)™, proposed as a low-risk, non-invasive, digital therapeutic candidate for behavior change in…
- Trial name
- DVx-T1D (NCT06264258)
- Testing
- DVx-T1D™ app
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Demyelinating Disease
Pharmacological Recruitment of Endogenous Neural Precursors to Promote Pediatric White Matter Repair: Establishing Correlations Between Visual Outcomes, Saccadic Function and MEG Oscillations in Children With Demyelinating Disorders in Comparison to Healthy Control Children
The neural circuits in our brains require a layer of insulation in order to transmit signals in a rapid and efficient fashion. This insulation is called White Matter and is comprised of a specific type of brain cell called an…
- Trial name
- NCT03010826
- Where
- 2 sites in Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Spinal Cord Injury
The Effect of FES on Children With Spinal Cord Injury
Regular exercise is strongly recommended to help maintain a healthy lifestyle. Unfortunately, children and young adults with damaged spinal cords may not be able to exercise regularly.
- Trial name
- NCT00291317
- Testing
- RT 300-P FES Cycle
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's Specialized Hospital
Child, Epilepsy
Evaluation of the Efficiency of Mobile Application for Parents of Children With Epilepsy
Introduction: support to family and child related to epilepsy, controls or when they come for urgent reasons. Solutions must be found to ensure its continuity. this support.
- Conditions
- Child, Epilepsy, Education, Mobile Application
- Trial name
- NCT04343352
- Testing
- implementation of mobile epilepsy training program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- DILEK SAYIK
Migraine, Pediatric Migraine
PEDİATRİC MİGRAİNE PATİENTS İN FİNDİNGS
Migraine is a common neurological disease in the pediatric population. However, studies investigating the clinical symptoms associated with the different phases of migraine attacks (prodrome, aura, postdrome), particularly in…
- Trial name
- NCT07593287
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mersin University
Emergence Delirium
Emergence Agitation of Sevoflurane in Pediatric
Low dose nalbuphine versus dexmedetomidine on prevention of emergence agitation in children
- Trial name
- NCT06830564
- Testing
- we will give the patient 0.1 mg nalbuphine 15 min before the end of the procedure, we will give the patient 0.5 mg dexmedetomidine 15 min before the end of the procedure
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain Management, Orchiopexy
Comparison of the Analgesic Efficacy of Transversalis Fascia Plane Block and Posterior Quadratus Lumborum Block in Pediatric Patient Undergoing Orchiopexy: A Prospective Observational Study
It was planned to compare the analgesic efficacy of the transversalis fascia plane block and the posterior quadratus lumborum block in children aged 1 to 7 years undergoing orchiopexy, by evaluating their FLACC scores and the…
- Conditions
- Pain Management, Orchiopexy, Transversalis Fascia Plane Block, Quadratus Lumborum Block
- Trial name
- NCT07286799
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Obstructive Sleep Apnea, Balance
Functional Assessment and Sleep Apnea in Obese Children and Adolescents
Childhood obesity increases significantly, and determines several complications in childhood and adulthood, and the worldwide prevalence of childhood obesity has shown a rapid increase in recent decades.
- Conditions
- Obstructive Sleep Apnea, Balance, Obesity, Childhood
- Trial name
- NCT05563311
- Testing
- Exercise on High-intensity interval training
- Where
- Brazil
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Traumatic Brain Injury, Brain Injuries
Multimodal Monitoring of Cerebral Autoregulation After Pediatric Brain Injury
Various methods have been studied to evaluate autoregulation. However, there is currently no universally accepted technique to assess integrity of the cerebral autoregulation neurovascular system.
- Conditions
- Traumatic Brain Injury, Brain Injuries, Brain Injury, Vascular
- Trial name
- NCT04242602
- Testing
- Transcranial Doppler
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Pain
Clinical Assessment of Pain Processes in Pediatric Patients With Chronic Musculoskeletal Pain
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain during childhood does not only impact physical and psychological aspects of daily life but may…
- Trial name
- MSK (NCT04308044)
- Where
- Canada
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Obesity, Adolescent
Increased Protein at Breakfast for Weight Management in Overweight Adolescents
Adolescent obesity, negatively affecting the lives of over 18 million (34%) US adolescents, continues to be a major public health concern due to the increased risk of developing chronic diseases, including type 2 diabetes.
- Trial name
- NCT03146442
- Testing
- Breakfast
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Insomnia
Helping Young Children Sleep
The investigators are conducting a randomized trial of behavioral treatments for young children with insomnia. The investigators are comparing the improvement in sleep patterns after families are given access to Internet sleep…
- Trial name
- NCT01729715
- Testing
- Internet, DVD
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Concussion, Brain, Concussion, Mild
The Role of Cerebral Oximetry in Pediatric Concussion Assessment
The purpose of this study is to determine whether there is a difference in cerebral oxygenation as measured by near-infrared spectroscopy (NIRS) in children with concussion and healthy controls.
- Conditions
- Concussion, Brain, Concussion, Mild, Traumatic Brain Injury
- Trial name
- NCT02036333
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University