Clinical trials: Pediatric Population
Diabetes Mellitus, Type 1, Type1diabetes
Group Education Trial to Improve Transition in Type 1 Diabetes
The investigators will conduct a randomized controlled trial (RCT) to examine group education visits as an innovative and potentially cost-effective approach to transition care delivery, that can be easily integrated into usual…
- Conditions
- Diabetes Mellitus, Type 1, Type1diabetes, Insulin Dependent Diabetes
- Trial name
- GET-IT-T1D (NCT03703440)
- Testing
- Active arm, Control arm
- Where
- 2 sites in Canada
- Volunteers
- 212 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Myopia
Myopia Control: a Comparison Study Between Atropine and MiSight
This research project aims to provide additional knowledge of pharmacological and optical methods of myopia control and to gain a better understanding of the biometry of the pediatric eye, which contributes to the onset and…
- Trial name
- NCT05815784
- Testing
- Atropine, MiSight contact lenses
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pediatric Disorder
Comparing the Difference in Pain Control in the Pediatric General Surgery Population: to Alternate or Combine Acetaminophen and Ibuprofen?
To examine the difference in pain control in the pediatric general surgery population alternating acetaminophen and Ibuprofen q 3 hours vs giving them simultaneous combination therapy around the clock.
- Trial name
- NCT06505148
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor Research Institute
Cardiac Toxicity, Unspecified Childhood Solid Tumor, Protocol Specific
Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as enalapril, may protect normal cells from the toxic effects of chemotherapy.
- Trial name
- NCT00003070
- Testing
- enalapril maleate, quality-of-life assessment
- Where
- 61 sites in United States, Canada and 1 more
- Volunteers
- 13 people
- Sponsor
- Children's Oncology Group
Neuroblastoma, Sarcoma
Pediatric Solid Tumor Metabolism [A Prospective Study Exploring Metabolism of Solid Tumors in Pediatrics]
To explore metabolic phenotypes of children with extra-cranial solid tumors and compare these with their histopathological and genetic alterations to discover potential novel biomarkers and therapeutic targets to improve outcomes…
- Conditions
- Neuroblastoma, Sarcoma, Pediatric Cancer
- Trial name
- NCT03686566
- Testing
- 13C-glucose, No glucose infusion
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Adiposity, Childhood Obesity
Early Life Intervention in Pediatrics Supported by E-health
Childhood obesity in early life contributes to the development of specific NCDs, i.e. adult obesity. Unhealthy diet and low level of physical activity are lifestyle risk behaviors associated with chronic, systemic inflammation…
- Conditions
- Adiposity, Childhood Obesity, Adolescent Obesity, Non-communicable Disease
- Trial name
- ELIPSE-I (NCT06208345)
- Testing
- Life-Style app
- Where
- Switzerland
- Volunteers
- 148 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pediatric Obesity, Pediatric Overweight
Reducing Barriers to Behavior Change Among Youth With Pediatric Overweight and Obesity
The purpose of the study is to examine the extent to which two different reward systems implemented in the context of a multi-family pediatric weight management group differentially promote adoption of healthy eating and activity…
- Trial name
- NCT00863083
- Testing
- Multifamily weight management intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical College of Wisconsin
Epilepsy, Focal Cortical Dysplasia
Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery
Refractory epilepsy, meaning epilepsy that no longer responds to medication, is a common neurosurgical indication in children. In such cases, surgery is the treatment of choice.
- Conditions
- Epilepsy, Focal Cortical Dysplasia, Tuberous Sclerosis, Hemimegalencephaly
- Trial name
- NCT04344626
- Testing
- Intra-operative brain tonometry
- Where
- 2 sites in United States, Canada
- Sponsor
- University of California, Los Angeles
SARS-CoV2
Impact of COVID-19 on Pediatric Dental Practice During First, Second And Third Wave.
Assessment of impact of covid-19 on pediatric dental practice during first, second and third wave among a group of pediatric dentists.
- Trial name
- NCT04592510
- Where
- Egypt
- Volunteers
- 345 people
- Sponsor
- Cairo University
Exercise
Active Play Intervention for Preschoolers
The goal of this randomized clinical trial is to examine the effects of a planned movement in preschool-aged children. The main question is to determine What are the effects of a planned movement program on physical activity…
- Trial name
- Active Play (NCT05744791)
- Testing
- Active Play planned movement program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Auburn University
Angulation Deformity of Long Bone (Disorder), Acquired Deformity of Knee Joint (Disorder)
Use of Motion Sensors in Correction Procedures of Long Bone Deformities in the Pediatric Age Group
Motion sensors will be used in long bone deformity surgery in pediatric patients. In patients whose deformity status is determined before the surgery, 2 wires will be placed in the same plane from the proximal and distal of the…
- Trial name
- NCT06516497
- Testing
- Group using traditional method in long bone deformity correction, Group using computer-aided sensors in long bone deformity correction
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ataturk University
Pediatric ALL, Surgery
Concealed Penis in Pediatric Age Group
Background: Comparison between three different surgical techniques in the management of concealed penis. Methods: This prospective interventional non-randomized study included 150 pediatric patients with concealed penis.
- Conditions
- Pediatric ALL, Surgery, Urologic Diseases
- Trial name
- NCT05565040
- Testing
- Circumcision in concealed penis
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Egyptian Biomedical Research Network
Arrhythmia
Electrocardiogram (ECG) Recordings in Paediatric Population
The primary goal of this protocol is to collect ECG signals from paediatric patients using 4 surface electrodes placed in the configurations proposed for the Cameron Health, Inc.
- Trial name
- NCT00399386
- Testing
- EP, ICD, Ablation
- Where
- United Kingdom
- Volunteers
- 62 people
- Sponsor
- Boston Scientific Corporation
Anesthesia
Oral Dexmedetomidine in Pediatric MRI
The objective of this preliminary study is to assess the utility of oral dexmedetomidine as the sole sedative agent in pediatric population undergoing MRI.
- Trial name
- NCT05619627
- Testing
- Dexmedetomidine, General Anesthesia (control group)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Soroush Merchant
Sickle Cell Disease
Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease
The purpose of the study is to Evaluate the Effect of Ticagrelor versus Placebo in Reducing the Rate of Vaso-Occlusive Crises in Paediatric Patients with Sickle Cell Disease
- Trial name
- HESTIA3 (NCT03615924)
- Testing
- Ticagrelor
- Where
- 55 sites in United States, Belgium and 14 more
- Volunteers
- 193 people
- Sponsor
- AstraZeneca
Atopic Dermatitis
Assessment of Pruritus Improvement With Pimecrolimus Treatment on the Areas Affected by Mild-to-moderate AD, in Patients 2- to 11- Year-old
The purpose of this study is to assess the efficacy and safety of pimecrolimus cream 1% in relation to the improvement of pruritus in pediatric patients (2- to 11- year-old) with mild to moderate atopic dermatitis.
- Trial name
- NCT00510003
- Testing
- Pimecrolimus
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- Novartis Pharmaceuticals
Disorder of Urinary Stent, Ureteral Spasm
Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal
This study plans to learn more about whether ibuprofen can reduce pain after removal of a ureteral stent more than a placebo. Some patients experience pain after removal of a ureteral stent.
- Conditions
- Disorder of Urinary Stent, Ureteral Spasm, Ureteropelvic Junction Obstruction, Urolithiasis
- Trial name
- NCT02140970
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Colorado, Denver
Asthma
Nebulized Fluticasone Propionate VS Oral Prednisone in Chinese Pediatric and Adolescent Subjects With an Acute Exacerbation of Asthma
This is a multicentre, randomized, double-blind, double-dummy, active-controlled, parallel-group study to determine the efficacy and safety of nebulized fluticasone propionate 1mg twice daily compared with oral prednisone…
- Trial name
- NCT01687296
- Testing
- fluticasone propionate inhalation solution, oral prednisone, salbutamol
- Where
- 11 sites in China
- Volunteers
- 261 people
- Sponsor
- GlaxoSmithKline
Mental Health Disorder
CoCo-20: a Longitudinal Follow-up Study of the French Paediatric Population During and After the Coronavirus Pandemic COVID-19
In the context of a viral outbreak and of widespread quarantine measures, a significant increase in psychological disorders, such as stress or fear behaviours, had previously been observed.
- Trial name
- CoCo-20 (NCT04498416)
- Testing
- Quantitative and qualitative assessments of mental health
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Fondation Lenval
Cancer
The Feasibility Of a Daily Diary Methodology With a Pediatric Cancer Population
This investigation seeks to determine the feasibility of an electronic diary methodology among pediatric cancer patients and healthy matched controls.
- Trial name
- DIARY1 (NCT01477255)
- Testing
- iPad
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital