Clinical trials: Pediatric Sedation
Anxiety, Anesthesia
The Association Between Parent Anxiety and Sedation Anesthesia Doses in Pediatric Endoscopy
Our study was planned as a prospective, single-center study between 20 January 2022 and 20 April 2022. All patients between the ages of 1-18 who will undergo upper or lower gastrointestinal endoscopy and their parents will be…
- Trial name
- NCT05210829
- Testing
- stationary and trait anxiety scale
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Ventilator Lung; Newborn
NIPE as an Indicator of Pain in Sedated/Ventilated Patient Under 3 Years-old Hospitalized in Intensive Care Unit
The main objective is to assess correlation between Newborn Infant Parasympathetic Index values and external evaluation by Comfort Behaviour Scale during painful medical cares in sedated intubated children admitted in pediatric…
- Trial name
- NIPE (NCT04195672)
- Testing
- NIPE (MDoloris®) and CBS values
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Lille
Dental Anxiety in Children, Child Behaviour
Comparative Evaluation of Intranasal Atomized Midazalom Combined With Nitrous Oxide Versus Nitrous Oxide Monotherapy
The rationale of this trial is to evaluate whether combining intranasal atomized midazolam with nitrous oxide offers better behavior management leading to successful treatment completion in comparison with using nitrous oxide…
- Trial name
- NCT07876024
- Testing
- Midazolam (Intranasal), Nitrous oxide/oxygen inhalation sedation alone
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Nurse's Role, Bispectral Index
Nurse-Led BIS-Guided Sedation Protocol in Pediatric Intensive Care
Pediatric intensive care sedation is traditionally based on subjective clinical scales. Bispectral Index (BIS) monitoring provides an objective EEG-based assessment of sedation depth.
- Conditions
- Nurse's Role, Bispectral Index, Pediatric Sedation
- Trial name
- NCT07252024
- Testing
- BIS-Guided Sedation Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Caries of Infancy, Dental Anxiety
Intranasal Sedation With Dexmedetomidine and Ketamine in Pediatric Dentistry (NASO II)
Parallel clinical trial focusing on procedural pediatric sedation in the dental setting. Children will be randomized to treatment according to a predetermined sequence of interventions consisting of: 1.
- Trial name
- NCT03290625
- Testing
- Dexmedetomidine Hydrochloride, Ketamine Hydrochloride
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Upper Gastrointestinal Endoscopy
Sedation for Upper Gastrointestinal Endoscopy in Pediatric Patients
The purpose of this study is to compere between Propofol-Ketamine combination and Dexmedetomidine-Ketamine combination for sedation in upper gastrointestinal endoscopy in paediatric patients.
- Trial name
- NCT02863861
- Testing
- Dexmedetomidine-ketamine, propofol-ketamine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sedation
Safety And Efficacy Of Dexmedetomidine Sedation In Intubated Mechanically Ventilated Infants With Respiratory Failure
Dexmedetomidine is a highly selective α2-agonist with hypnotic, analgesic, and anxiolytic properties. Despite off-label administration, dexmedetomidine has found a niche in critically ill mechanically ventilated neonates and…
- Trial name
- DEXinPICU (NCT02996058)
- Testing
- Dexmedetomidine 0.35µg/kg /h, Dexmedetomidine 0.5µg/kg /h
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Failed Conscious Sedation During Procedure
The Efficacy and the Safety of Dexmedetomidine Sedation on the Pediatric Intensive Unit(PICU) Patients.
To observe the efficacy and safety of dexmedetomidine sedation on the patients admitted to the pediatric intensive care unit after surgery.
- Trial name
- NCT02296073
- Testing
- Midazolam, Dexmedetomidine, Fentanyl
- Volunteers
- 120 people
- Sponsor
- Anhui Provincial Children's Hospital
Respiration Disorders
Randomized Study of Propofol Versus Fentanyl and Midazolam in Pediatric Patients Requiring Mechanical Ventilation and Sedation Therapy
OBJECTIVES: I. Assess the degree of amnesia afforded by study sedatives relative to the patient's intensive care unit experiences. II.
- Trial name
- NCT00004424
- Testing
- fentanyl, Midazolam, propofol
- Volunteers
- 120 people
- Sponsor
- FDA Office of Orphan Products Development
Child Behavior, Dental Caries
Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment
Randomised clinical trial to test the efficacy, safety and cost-effectiveness of sedatives; masked, controlled, parallel design with three arms, phase 4.
- Trial name
- NASO (NCT02447289)
- Testing
- Intranasal ketamine, Oral ketamine, Intranasal midazolam
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Adverse Event
Comparison of the Sedation Effect of Esketamine and Sevoflurane for Pediatric Ophthalmological Procedure
Emergence agitation is the most common reason for post-anesthesia care unit delay. Sevoflurane is used frequently inhalational anaesthetic agent to provide pediatric anaesthesia because of the nonirritant nature.
- Trial name
- NCT05321160
- Testing
- Esketamine, Sevoflurane
- Where
- China
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Child, Intensive Care Unit Acquired Weakness
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
While mortality in U.S. pediatric intensive care units (PICUs) is improving, surviving children frequently develop persistent physical, cognitive, and psychological impairments.
- Conditions
- Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
- Trial name
- PICU Up! (NCT04989790)
- Testing
- PICU Up!
- Where
- 11 sites in United States
- Volunteers
- 1,470 people
- Sponsor
- Johns Hopkins University
Sedation
Effect & Safety of Inhaled Isoflurane vs IV Midazolam for Sedation in Mechanically Ventilated Children 3-17 Years Old
This is a study to compare safety and efficacy of inhaled isoflurane delivered by the AnaConDa-S (Anaesthetic Conserving Device (ACD)) versus intravenous midazolam for sedation in mechanically ventilated children admitted to an…
- Trial name
- IsoCOMFORT (NCT04684238)
- Testing
- Midazolam, Isoflurane
- Where
- 24 sites in France, Germany and 3 more
- Volunteers
- 94 people
- Sponsor
- Sedana Medical
Stress
Evaluation Of Stress Levels Of Pediatric Dentist Performing Dental Treatment In The Operating Room
This study will measure the stress levels of pediatric dentists performing dental treatments under deep sedation and general anesthesia.
- Trial name
- NCT07541508
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Pediatric Cancer, Analgesia
Intranasal Versus Intravenous Drug in Painful Procedure for Outpatient Oncologic Participants
Pain is a vital sign that depends on personal experience involving different factors such as previous sensory and emotional experience, age, spiritual and cultural aspects, that makes it harder to evaluate, especially in young…
- Conditions
- Pediatric Cancer, Analgesia, Procedural Pain
- Trial name
- NAIVe (NCT04621110)
- Testing
- intranasal dexmedetomidine, intranasal fentanyl, intravenous ketamine (ketalar®)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Sedation
A Study to Learn About the Study Medicine - Precedex in Children From Japan.
The purpose of this study is to look at the safety of Precedex when it was used to calm children at procedures or tests under actual medical practice in Japan.
- Trial name
- NCT06085573
- Testing
- Dexmedetomidine Hydrochloride
- Where
- Japan
- Volunteers
- 111 people
- Sponsor
- Pfizer
Improving Informed Consent Process
Use of a Multimedia Presentation for Informed Consent
This is a prospective cohort study in which the standard verbal informed consent process for ketamine sedation is compared to a multimedia informed consent process.
- Trial name
- NCT01955070
- Testing
- Multimedia Presentation for Ketamine sedation
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Nationwide Children's Hospital
Laceration
Intranasal Ketamine for Procedural Sedation in Pediatric Laceration Repair
The purpose of this study is to compare how well three different doses of ketamine, given as a spray into the nose, help to sedate children and help them tolerate repairs of cuts on their faces.
- Trial name
- NCT00451724
- Testing
- Intranasal ketamine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Pediatric, ED95
The ED95 of Single Intravenous Bolus Remimazolam Besylate in Pediatric Patients During General Anesthesia Induction
Due to the incomplete development of systems and low pain thresholds in the pediatric population, good general anesthesia is required during the perioperative period to ensure the smooth progress of the surgery.Propofol is often…
- Conditions
- Pediatric, ED95, Sedation, General Anesthesia
- Trial name
- NCT06061159
- Testing
- Remimazolam besylate
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Deep Sedation, Dental Treatment
High-flow Nasal Oxygenation During Deep Sedation in Pediatric Dental Patients
It is important to choose an appropriate oxygenation technique during intravenous deep sedation in pediatric dental treatment. The study is to evaluate the efficacy and safety of high-flow nasal oxygenation in intravenous deep…
- Conditions
- Deep Sedation, Dental Treatment, Pediatric Patients
- Trial name
- NCT05762692
- Testing
- High-flow nasal oxygenation device
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University