Clinical trials: Pediatrics
Obesity
Anthropometric Assessment of Abdominal Obesity and Health Risk in Children and Adolescents
Childhood obesity is a major public health issue, and the identification of children who are at increased risk of health problems due to their obesity is a priority for modern health care.
- Trial name
- Waist (NCT01595100)
- Where
- United States
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Hypercholesterolemia
Screening for Hypercholesterolemia in Children Using Dried Blood Spot
Purpose: Heterozygous Familial Hypercholesterolemia (HeFH) is a common genetic disease responsible for premature atherosclerosis.
- Trial name
- CHOLESPOT (NCT05191355)
- Testing
- blood test
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cardiomyopathy, Dilated, Cardiomyopathy, Hypertrophic
Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy
This study will investigate whether there is an association between insulin resistance and cardiac function in children with dilated or hypertrophic cardiomyopathy.
- Conditions
- Cardiomyopathy, Dilated, Cardiomyopathy, Hypertrophic, Insulin Resistance
- Trial name
- NCT04222101
- Testing
- Oral glucose tolerance test
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Le Bonheur Children's Hospital
Diabetes, Pre-diabetes
Metformin at the Cellular Level and Dosing for Diabetes Mellitus (DM)
The investigators know that metformin works at the level of the cells in the body by acting on a protein called Cyclic amine monophosphate- Response Binding Elements (CREB) binding protein or Constitutive Reverter of eIF2α…
- Conditions
- Diabetes, Pre-diabetes, Obesity
- Trial name
- NCT01876992
- Testing
- Metformin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Preoperative Anxiety
A Mobile Application for Child-focused Perioperative Education
The investigators developed a child-friendly mobile application to support accessible, interactive patient/caregiver education about pediatric tonsillectomy.
- Trial name
- NCT06054282
- Testing
- "Ready for Tonsillectomy" educational mobile application
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Anxiety, Lacerations
Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department
Laceration repair can cause significant anxiety in children. As open wounds account for 21-25% of injuries in children presenting to the emergency department, the management of anxiety is of great importance.
- Trial name
- NCT02618772
- Testing
- Midazolam, Saline
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Diabetes Type 1, Proteomics
Proteomic Analysis in Paediatric Diabetes Type 1 (PAPD)
The aim of the present study is to investigate a targeted proteomic analysis in plasma of children - of Greek origin- with type 1 diabetes (DT1) and its correlation with the electrophysiological findings that accompany diabetic…
- Conditions
- Diabetes Type 1, Proteomics, Diabetic Peripheral Neuropathy
- Trial name
- PAPD (NCT04257877)
- Testing
- Blood sampling
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Arrest, Bone
Anabolic Steroid and Propranolol in Paediatric Burn
propranolol and anabolic steroids have a role in pediatric burn patients and their combined effects are to be studied here. They decrease the catabolic response to burn trauma and minimize the duration of growth arrest hence…
- Conditions
- Arrest, Bone, Development, Growth
- Trial name
- NCT05805553
- Testing
- Propranolol, Nandrolone Decanoate
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Surgery
Immersive Care - Virtual Reality(VR) 360 Pediatric Surgery Preparation.
Context: This study is part of the larger Immersive Care project which (in short) seeks the connection between technology and care by conducting feasibility studies with promising technological interventions tailored to care.
- Trial name
- NCT04658030
- Testing
- VR 360 video surgery preparation, Care as usual
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Thomas More University of Applied Sciences
Pediatric Adenotonsillectomy, Post Operative Analgesia
Dexmedetomidine in Pediatric Tonsillectomy
The hypothesis of this study is that the administration of an intra-operative dose of dexmedetomidine will result in adequate analgesia without respiratory depression thereby resulting in an early discharge from the post…
- Trial name
- NCT01057381
- Testing
- Dexmedetomidine 0.75 mcg/kg, Morphine 50 mcg/kg, Morphine 100 mcg/kg
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Myopia
Contact Lenses and Myopia
The objective of this study is to determine if multifocal contact lenses affect accommodation and/or binocular vision when worn by pediatric patients.
- Trial name
- CLAM (NCT02180347)
- Testing
- Contact lenses
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Solid Organ Transplant
iParent2Parent Program for Parents of Pediatric Solid Organ Transplant Recipients
The iParent2Parent (iP2P) program is a new, innovative virtual mentorship program that will connect parents one-to-one with other parents of pediatric solid organ transplant (SOT) recipients who are trained to offer vital peer…
- Trial name
- NCT05968807
- Testing
- iParent2Parent Program
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Peripheral Intravenous Catheter
The Effect of the Vein Imaging Device Used in Peripheral Intravenous Catheter Application on the Success of the Procedure in Patients Coming to the Pediatric Emergency Department
Peripheral Intravenous Catheter (PIC) application in pediatric wards of hospitals; It is used in the administration of drugs that require diarrhea, vomiting, dehydration or high serum concentration, resistant infections…
- Trial name
- NCT06233214
- Testing
- vein imaging device
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Community-Acquired Pneumonia, Vitamin a
The Effect of Adjunct Vitamin a on Community-Acquired Pneumonia in Southern Iranian Children: a Randomized Clinical Trial
This randomized clinical trial included 105 children with CAP who were admitted to Bandar Abbas Children's Hospital. Participants were randomly assigned to two groups: a control group receiving standard antibiotic therapy and an…
- Trial name
- CAP Vitamin A (NCT06677684)
- Testing
- Vitamin A
- Where
- Iran
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hormozgan University of Medical Sciences
Magnetic Field Exposure, Temperature Change, Body
Increase in Temperature in Children Undergoing MRI
An increasing number of children undergo Magnetic Resonance Imaging (MRI). In MRI, radio waves and magnetism are used to form images of the body's interior, to diagnose and monitoring diseases in children.
- Conditions
- Magnetic Field Exposure, Temperature Change, Body, Children, Only
- Trial name
- HOT-MR (NCT04317378)
- Testing
- Braun thermoscan /, IRT 6520
- Where
- Denmark
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Paediatric Trauma
Paediatric Rural vs Urban Trauma
Retrospective cohort study examining paediatric trauma admission over 1 year in a rural hospital vs urban centre
- Trial name
- NCT04760886
- Testing
- Type of hospital (rural DGH vs Urban MTC)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mrs Jennifer M Dunn
Pain, Pediatrics
Pain Neuroscience Education for Middle School Students
This project was designed as a single-blind, randomised controlled, prospective intervention study. The research question of the project is 'Is pain neuroscience education an effective method to improve various aspects of child…
- Conditions
- Pain, Pediatrics, Neuroscience Pain Education, Physical Activity
- Trial name
- NCT06869369
- Testing
- Turkish PNE4Kids
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Immunization
Testing Educational Materials in a Paediatric Setting
Immunization procedures are a common source of iatrogenic pain for infants. A recently developed clinical practice guideline, led by Taddio et al., created evidence-based strategies for management of immunization pain.
- Trial name
- NCT01713322
- Testing
- Pain management education, No pain management education
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Brain Cancer
Controlling Coordination After Childhood Cerebellar Cancer, a Pilot Study
Posterior fossa tumours (PFT) account for 2/3 of childhood brain cancers. They can be highly malignant requiring combined chemotherapy and radiotherapy post-surgery for a >50% chance of cure.
- Trial name
- 5C-pilot (NCT04501731)
- Testing
- Transcranial Magnetic Stimulation (TMS), Magnetic Resonance Imaging (MRI), Motor assessment
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Respiratory Tract Infections
A Comparison of Respiratory Sample Collection by a Parent or by a Healthcare Worker
The investigators are aiming to learn more about respiratory infections in young children in the community. To prepare for a larger project, the investigators are conducting this study to get information about the best way to…
- Trial name
- ReSPeCT (NCT00966069)
- Testing
- Parent collection, Healthcare worker home visit
- Where
- Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The University of Queensland